Identifiers and Description

Gene Model Identifier

TTHERM_00449390

Standard Name

PKD1 (protein kinase domain)

Aliases

PreTt15452 | 52.m00230 | 3811.m00988

Description

PKD1 kinase domain protein; Protein kinase domain containing protein. Sequence similarity to a protein kinase family unique to Tetrahymena thermophila (Eisen et al.- 2006).

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Molecular Function

Biological Process

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_16860.1 9.995938456217754e-149
Description: protein kinase domain-containing protein (437 aa)
WormBase WBGene00018860 9.995938456217754e-149
Description: status:Partially_confirmed UniProt:H2KYF2 protein_id:CCD62874.1
DictyBase DDB_G0276465 2.999758165421992e-18
Description: sepA on chromosome: 2 position 6942806 to 6946733
Oxytricha Contig15160.0.g60 5.000468829272308e-18
Description: Protein kinase domain
WormBase WBGene00017033 9.997764199084386e-16
Description: locus:nekl-4 Serine/threonine-protein kinase D1044.8 status:Partially_confirmed UniProt:P84199 protein_id:CCD68375.1
SGD YAR019C 9.997764199084386e-16
Description: CDC15 Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II
Tetrahymena borealis EI9_20691.1 9.997764199084386e-16
Description: hypothetical protein (480 aa)
Stentor Coeruleus SteCoe_37998 0.0000000001026187963170189
Description: None

General Information

No. Gene Name(s) Paragraph Text
35 PKD1 Tetrahymena thermophila PKD1 (protein kinase domain) is homologous with other protein kinase-like proteins that are involved in catalytic functions and phosphorylation in cellular processes. PKD1 is located near the C-terminus of the protein appears to contain only one known domain (E-value= 1.2x10-42) in the protein kinase family although the substrate specificity of the PKD1 is unknown. Paragraph by: Victoria Nguyen and Joseph Grotts (undergraduates), Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges.

Associated Literature

  1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences 

>TTHERM_00449390(coding)
ATGGCATTTTAAAGATGCTATATACAACAAAGTGCTTTCTTTTAAATAAAGAAGTTTAAT
TAAAGTAGTATTGTAATTGGCTAAATTATATACCCTTAAACTCTACCGATTTTTTGGAAC
TCTAATGGAATTTCGTCTGAAAATAGTTTTTAGACTGTTTCATAGGAATTAGAGGTTAAT
GGAGATGAAAATGAAAATGATGAATTGGAAGATATTTTAACAAATGGAAATAACAGTTTT
ATAGTGAATACTCAAAAAAATTCTTATGTAATTGAAGATAATTTAATTACTAAAATTTTA
CCTTAAACAAATGTTTACTTATTCTTATATAACCTTCAATTTAATGGTAAATTTTATGAT
GAAATATAAGACATTAGTGAGGAGGTTTAGAAATATGCAGATTTTCCAAAATTCAACTAT
AACTTATAATAAAGAGATTAATATAACAAAATTATGAGTTACAGAGATCCATTTTCTGAA
AATGAACAAAAAATTGAATATGTTTATTAGATCAAATTAAAATATGGATAATTTATTTAA
AAACTTTATCAATAAGAAAATAAAACAAGTCTTTATTTAACTTATACTTCAAATTTTGTT
GTAATATCTTAAATAAATGATGGAGACACAATATCATTTATTTTATCATTTGCTTTTAGT
CTCTTGATATTTAGAAGATCGAAAAAGAGAAAAGAAATTAGAGCTCAAACTGAGGATTTG
ATATATAAATAGGTTATTTAAATTTCTAGATAGGAATTTTAAAAGAAATATGAACTAAAT
TATAGAGATTCTATTGGATGTGGTAGCTTTGGACAGGTCTATAAAGTTAAAAATAAATAT
AAACAAATTATAAAAAATCCTGATATTTTACAAAACATGCCAGATTATTACGCTTGCAAG
CAAATACATATATCTTAAGATGGAGAAAACTAGAGTTAATAGATTTTCCATGAAATCGAA
GTGTTAGAAAAGCTAAAAAAATATGAATATGTAATTAAATTACAAAATTATATTATTGAA
GAAAGGTCAGCATATCTTGTCTTAGATCTAGCAGAGTCCACATTATAGGATAAAATAAAT
GAAAAGTAGGCAAATTCAGAAAAGTTTGATGAGAGCGAAATTGTGAAGTTTTTATCCTAA
ATAGGTAAAACTTTAGCATTAATATACATTGAAGAAGGGATAGCTCATAGAGATATTAAG
CCTTCAAATATACTAATTAAAGATGACAATTTTTACTTATCTGATTTCGGATGTGCAGAA
ATACTATTTGAATCGCAAGAAGCTAGAAACAATTTAGTCATGGGAACTTTAAAATGGATG
TCACCTGAATTAAAAGAAATGAAGAAAAATCAAGTAGTTGACTATTTCAAAAGTGACATA
TTTAGTTTGGGAATGTTATTGCTTTATATGCTTACTCTTTCAGATATTTCTTCTGTAAAC
TCAGATGAGTTTACTAAGAACCAAAAGATAAGAATCATGAAAAATTATTGTAAAGGTATT
TCTAATGAAATAATTTTACTTATAAAAAGAATGTTAGAAACAAACCCTGACAATAGGCCT
GATGCAGCAATAATAATTAATGCAATTTAAGATATAGAAAATAACTTTAAATAAAAAAAT
TTAAGCAAAGATTTATGA


>TTHERM_00449390(gene)
ATGGCATTTTAAAGATGCTATATACAACAAAGTGCTTTCTTTTAAATAAAGAAGTTTAAT
TAAAGTAGTATTGTAATTGGCTAAATTATATACCCTTAAACTCTACCGATTTTTTGGAAC
TCTAATGGAATTTCGTCTGAAAATAGTTTTTGTATTTATTAAATATTAGATAATAATTTA
CAGATAAAGTTTTATTATCATTATTAAGAGACTGTTTCATAGGAATTAGAGGTTAATGGA
GGTAATTTGTTTTTTATTAATTAATTTTATGAATAAATAATTAAGTAGAATTAATTTATA
ATTGATTTTTAAAGGGCATAGCTTTAAATTAGGTTAAATATATCGATTTAAATCTGAAGT
ATTTTAAATAAATTTGCTTCATAAAATCATATTATTTTACCAATTATTTTAAAAATTATA
ATTTCAAATATAAAATAATATAAAATATGAATCTTTTGTGTAATAATTCTTTTATTGTAA
ATAAATTAATAAATAAGTGAAGGAGATTTTGCAAGTATCTTAGTCAAATGATAGCTATTA
CTTTTATATTTTAGATAATCAGAATTAGGCTATATTATATTATGTAACTAAAAAACTCAT
TCTTAAATATTTATTGGATGAAAAACCTAAATTAATAAAGACTAATCTATTTACCTAACA
AATGAATAAATGCTTATATAAAATAGATAATATACAGTAGAATTTGTAATAAACAATTAT
TTTTTGTATAGATGAAAATGAAAATGATGAATTGGAAGATATTTTAACAAATGGAAATAA
CAGTTTTATAGTGAATACTCAAAAAAATTCTTATGTAATTGAAGATAATTTAATTACTAA
AATTTTACCTTAAACAAATGTTTACTTATTCTTATATAACCTTCAATTTAATGGTAAATT
TTATGATGAAATATAAGACATTAGTGAGGAGGTTTAGAAATATGCAGATTTTCCAAAATT
CAACTATAACTTATAATAAAGAGATTAATATAACAAAATTATGAGTTACAGAGATCCATT
TTCTGAAAATGAACAAAAAATTGAATATGTTTATTAGATCAAATTAAAATATGGATAATT
TATTTAAAAACTTTATCAATAAGAAAATAAAACAAGTCTTTATTTAACTTATACTTCAAA
TTTTGTTGTAATATCTTAAATAAATGATGGAGACAGTATTTATTAATATTATAGTTTTTT
ACTGAATAATAATCAAAAAGATTTACCTAGCAGCGCATTTATAACTTAATTTGTATATTT
TTAAACAGCAATATCATTTATTTTATCATTTGCTTTTAGTCTCTTGATATTTAGAAGATC
GAAAAAGAGAAAAGAAATTAGAGCTCAAACTGAGGATTTGATATATAAATAGGTTATTTA
AATTTCTAGATAGGAATTTTAAAAGAAATATGAACTAAATTATAGAGATTCTATTGGATG
TGGTAGCTTTGGACAGGTCTATAAAGTTAAAAATAAATATAAACAAATTATAAAAAATCC
TGATATTTTACAAAACATGCCAGATTATTACGCTTGCAAGCAAATACATATATCTTAAGA
TGGAGAAAACTAGAGTTAATAGATTTTCCATGAAATCGAAGTGTTAGAAAAGCTAAAAAA
ATATGAATATGTAATTAAATTACAAAATTATATTATTGAAGAAAGGTCAGCATATCTTGT
CTTAGATCTAGCAGAGTCCACATTATAGGATAAAATAAATGAAAAGTAGGCAAATGTAAG
AAGAAGAATTTTTTTTAATTTTCTTTACTTCATTTTCAAATAAAATTTTGTTTGATATTT
ATTATAGAATTAATATTTTTTTGAATAACTTACTTCAAAAGTTATTTAAACAATACAAAT
TTCTTTTTATTCATAAAATTAATTATCCCAAAACTCAAATTACTACTTTTATTGTTTTTC
TTTTTATATTCAAGATTAAAAATCTTTTTATTGTCTGTCTTACTGTTTTTTACCATAACA
TAACATAAGATAAATTTAAATTTTATTGCTTTGAAAATTTTATAAAATAATTTTGATTAA
TTTAATTAATTACTACTTTCAAAGATTTTATCAATAAATTTCAAGCTCTTTTTGTGTTAA
ATTATTTTTAAGTTATTAAAAATTTAAATTTCATTTAAAAAAATCGAAAAAAAGTCAGAA
AAGTTTGATGAGAGCGAAATTGTGAAGTTTTTATCCTAAATAGGTAAAACTTTAGCATTA
ATATACATTGAAGAAGGGATAGCTCATAGAGATATTAAGCCTTCAAATATACTAATTAAA
GATGACAATTTTTACTTATCTGATTTCGGATGTGCAGAAATACTATTTGAATCGCAAGAA
GCTAGAAACAATTTAGTCATGGGAACTTTAAAATGGATGTCACCTGAATTAAAAGAAATG
AAGAAAAATCAAGTAGTTGACTATTTCAAAAGTGACATATTTAGTTTGGGAATGTTATTG
CTTTATATGCTTACTCTTTCAGATATTTCTTCTGTAAACTCAGATGAGTTTACTAAGAAC
CAAAAGATAAGAATCATGAAAAATTATTGTAAAGGTATTTCTAATGAAATAATTTTACTT
ATAAAAAGAATGTTAGAAACAAACCCTGACAATAGGCCTGATGCAGCAATAATAATTAAT
GCAATTTAAGATATAGAAAATAACTTTAAATAAAAAAATTTAAGCAAAGATTTATGA


>TTHERM_00449390(protein)
MAFQRCYIQQSAFFQIKKFNQSSIVIGQIIYPQTLPIFWNSNGISSENSFQTVSQELEVN
GDENENDELEDILTNGNNSFIVNTQKNSYVIEDNLITKILPQTNVYLFLYNLQFNGKFYD
EIQDISEEVQKYADFPKFNYNLQQRDQYNKIMSYRDPFSENEQKIEYVYQIKLKYGQFIQ
KLYQQENKTSLYLTYTSNFVVISQINDGDTISFILSFAFSLLIFRRSKKRKEIRAQTEDL
IYKQVIQISRQEFQKKYELNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQNMPDYYACK
QIHISQDGENQSQQIFHEIEVLEKLKKYEYVIKLQNYIIEERSAYLVLDLAESTLQDKIN
EKQANSEKFDESEIVKFLSQIGKTLALIYIEEGIAHRDIKPSNILIKDDNFYLSDFGCAE
ILFESQEARNNLVMGTLKWMSPELKEMKKNQVVDYFKSDIFSLGMLLLYMLTLSDISSVN
SDEFTKNQKIRIMKNYCKGISNEIILLIKRMLETNPDNRPDAAIIINAIQDIENNFKQKN
LSKDL