Identifiers and Description

Gene Model Identifier

TTHERM_01031060

Standard Name

MCM8 (DNA replication licensing factor MCM8)

Aliases

PreTt22652 | 205.m00041

Description

MCM8 DNA replication licensing factor MCM8 putative; MCM2/3/5 family protein; Component of the MCM complex involved in DNA replication

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• DNA binding (IEA) | GO:0003677

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF00004 ) ATPase family associated with various cellular activities (AAA)
• ( PF00451 ) Scorpion short toxin, BmKK2
• ( PF00493 ) MCM P-loop domain
• ( PF01078 ) Magnesium chelatase, subunit ChlI
• ( PF07726 ) ATPase family associated with various cellular activities (AAA)
• ( PF07728 ) AAA domain (dynein-related subfamily)
• ( TIGR00129 ) formate dehydrogenase family accessory protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_20039.1	9.997093137033517e-262
	Description: MCM2/3/5 family protein (817 aa)
Oxytricha	Contig19212.0.g9	9.997093137033517e-262
	Description: MCM2/3/5 family
DictyBase	DDB_G0283009	7.002029054921595e-161
	Description: mcm8 on chromosome: 4 position 149067 to 151575
WormBase	WBGene00003156	3.000361869300436e-85
	Description: locus:mcm-4 status:Confirmed UniProt:Q95XQ8 protein_id:CCD69913.1
SGD	YGL201C	1.0001478224244938e-84
	Description: MCM6 Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex; forms a subcomplex with Mcm4p and Mcm7p
Stentor Coeruleus	SteCoe_14996	2.3455513385429143e-59
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01031060(coding)
ATGTCTAGTTTTAAAAGAGAATCAGATTTTTATTATAAAAGTCCAGGGAGATTAACTCAT
CCAAAAAAGAATAACGAGTCTTCGCTTAGCATAATTTAGCCTGAAATGAATAATAACAGT
AACTTTGATCATACATTACTACTCGAAAAGTGGAAGGACTACTTTTAAGATGACTGCAAA
ACATTTTATGATAACGATCCAAGACATGTGATGTTGCTTTCATTTTTTGAATGTTATAGA
TTGTATTAATAATTTAAAGATATTATAGAATGGACTAACTTAAAAAGAAATGATTTATCA
GAAGCCTATGTTGATTTTATAAAACTAAAGAATTTCGATGATGAAACTTGTAAGGAAGCT
GAATTATTTAAATAAGAAATAGAAAAGGATGTTAATGATACTATAAATTCTCTTAGCTTG
GCTTTGGATTGCGTAAGAGTTCATCTGTTAGGCTAAAAAAGAAAGAAAGTGATAGTTCGC
TTATACAATTATGATTAATCAGTTTAGCTGAGAGATATTAAAGCTAATATAATTAATAAA
TATCTTTAAGTAAAGGGTGTTGTTTTGAAGACTTCTCCTGTTTAAGTTATGATTAACGAA
ATGACTTTTTAGTGTCTTGATTGCAAATAAAACTAAGTCATTAAATTTCTTTATGGCATT
TATTCCTAACCTACAAAATGCCTGAATACAAAATGCAAGGGAACTAAATTTAATCCAGAT
AAAACTAGAGCAAAAGCCAGCTTGTATCAAAGAATCAAGCTTTAAGAAATAGAAGAAGAT
GACAAAGGAAGTGGAAGAGTTCCTCGTACTTTAGAATGTGAACTAAGAGATAATCTTGTT
AATACTACAATTAATGGAGATATTGTTACTGTTTCTGGATTATTAAGAACTGAAGCTGCA
GATTTAAGCTAATAAGGCAAAAAAACAATTGGTCTGCAATCTAATGTTATGGATGTAAAC
TGTTTGACTAATTCTAAAAATGAAAATAAACTTTTAAACGAAGATGAAGAAGAATTCTCT
GAAGAAGATATAATTATGGCTTAGACTTTGAGTGATGATCCACGTGTATTCCCAAGACTT
GTTAAATCTGTTTGTCCTACAATCTTTGGGCATGAGCTAGTAAAGGCAGGACTTTTGCTT
TCTATTCTAGGTGGAGCTCCAGTTAATGAGCTTTAAGGTATTTCTAATCCATTTGCTGAT
GACAATAAAATTTCATTTAGAAGCGACTGTCATGTTCTTTTAATTGGTGATCCTGGTTTA
GGTAAATCTTAGTTATTGAAATTTTTAGCCAATATCACTACTAGATCAATATATACATGT
GGAAGCAGCTCTTCTAACGCTGGTTTGACTGTTACAGTTACAAAAGATCCAGTTACTGGT
GAAAGTACGCTCGAAGCTGGTGCTCTTATTTTGAGTGATTAAGGTGTTTGTTGTATTGAT
GAATTTGATAAAATGTCTGCTGATCATTATGTCTTGTTAGAAGCTATGGAACAATAAACA
GTTTCTCTAGCTAAAAGTGGTGTCCTTTGCTCACTTTAATCAAGAGCAACTATTATAGCT
TCAGCTAATCCAAAAGAAGGACATTATAATAAATCAAAATAAATCAAGGATAATATTAAA
ATTAATAACGCAATTCTATCTAGATTTGATTTAATTTTCCTTCTATTAGATACTCCTGAT
CCAATGAGAGATTAAAAATTATCAGAACATATTATGAAACTGCATTCAAGAAAAAGAAAG
AAAGATGAAATGGGATAGTTTGTTTAGAAATAGCCTTAATACATGCAAGATACTGAATAC
AGTTCTTTGACAGAAAAATTATAAGCTGAGTGTGCAGAAGTTACTGAAAATCTAATTCTC
TCTCCTGCTATAATGAGAAAATATATTTAGTATGTGAAGAAATTTGTTCAGCCAGTACTT
AGTAGAGAAGCTGCTGAAATTATAAAGGAATTTTATTTAACTTTGAGAGAATCACATTTT
AATACTTCATCTATTCCAATTACAAACAGACAACTTGAGTCTCTAGTAAGACTTTCATAA
GCCCGTGCAAAAATAGAATGCAGAGATATAGTGACGAAAAAGGATGCTCTTGAAGTTGTT
GAGCTGATGTAAGAAAGTTTATTTGATTCTCTTGAAGATCTAAACTACGCTCGTGGAGCA
GGTGGCACTTCTTTATAAGTTAATAAGGGTTTGAAAAATATAAACCCAAACAATATAGGA
AGTCTTAGTGTGATGAAATAAACAAAGGTCTTCTTAGAAAGATTATAATAAGAAGCATCA
ATTAAAGGTTCATATTAATTCTCCTATAACGATTTAACAACTATAGCAAAGAGCATTAAC
ATGAATGTTGGAGATTTCAGTGAGTTTATTTCAAAGCTTAATCATTAATCTATGCTTATT
TTTAGAGGTAACAAAAACTATGAATTGGCAGCAAAAAGAAATTACTGA

>TTHERM_01031060(gene)
ATGTCTAGTTTTAAAAGAGAATCAGATTTTTATTATAAAAGTCCAGGGAGATTAACTCAT
CCAAAAAAGAATAACGAGTCTTCGCTTAGCATAATTTAGCCTGAAATGAATAATAACAGT
AACTTTGATCATACATTACTACTCGAAAAGTGGAAGGACTACTTTTAAGATGACTGCAAA
ACATTTTATGTAAAAAAAAAATAATAATTTTTAAAGAATTAAATGTAAAAGGATTTGGTC
ATATTTAATTTATTCGAAAGAAGACATATTTTTTAAGTGAATTATCAAAATAATTTATGA
TATAAAATTGATTAAATTTTTAAGATAGATATTTTTTAAATGAAAAAAAGGATAACGATC
CAAGACATGTGATGTTGCTTTCATTTTTTGAATGTTATAGATTGTATTAATAATTTAAAG
ATATTATAGAATGGACTAACTTAAAAAGAAATGATTTATCAGAAGCCTATGTTGATTTTA
TAAAACTAAAGAATTTCGATGATGAAACTTGTAAGGAAGCTGAATTATTTAAATAAGAAA
TAGAAAAGGATGTTAATGATACTATAAATTCTCTTAGCTTGGCTTTGGATTGCGTAAGAG
TTCATCTGTTAGGCTAAAAAAGAAAGAAAGTGATAGTTCGCTTATACAATTATGATTAAT
CAGTTTAGCTGAGAGATATTAAAGCTAATATAATTAATAAATATCTTTAAGTAAAGGGTG
TTGTTTTGAAGACTTCTCCTGTTTAAGTTATGATTAACGAAATGACTTTTTAGTGTCTTG
ATTGCAAATAAAACTAAGTCATTAAATTTCTTTATGGCATTTATTCCTAACCTACAAAAT
GCCTGAATACAAAATGCAAGGGAACTAAATTTAATCCAGATAAAACTAGAGCAAAAGCCA
GCTTGTATCAAAGAATCAAGCTTTAAGAAATAGAAGAAGATGACAAAGGAAGTGGAAGAG
TTCCTCGTACTTTAGAATGTGAACTAAGAGATAATCTTGTTAATACTACAATTAATGGAG
ATATTGTTACTGTTTCTGGATTATTAAGAACTGAAGCTGCAGATTTAAGCTGTATTTAAC
ATTTTTAAAATGAACTACAATAAAATTAATTATTGCTTAAAATAAACTTAAATTTAATAC
ATTTTATTTTTGACTTTCTTTTAATTCATATTTTAAAATTTAAAAGAATAAGGCAAAAAA
ACAATTGGTCTGCAATCTAATGTTATGGATGTAAACTGTTTGACTAATTCTAAAAATGAA
AATAAACTTTTAAACGAAGATGAAGAAGAATTCTCTGAAGAAGATATAATTATGGCTTAG
ACTTTGAGTGATGATCCACGTGTATTCCCAAGACTTGTTAAATCTGTTTGTCCTACAATC
TTTGGGCATGAGCTAGTAAAGGCAGGACTTTTGCTTTCTATTCTAGGTGGAGCTCCAGTT
AATGAGCTTTAAGGTATTTCTAATCCATTTGCTGATGACAATAAAATTTCGTAATTTACT
TAGATACATTCAAGTTTCTTATTTGAAATTTTAAACTATTTATTTATTTTAGATTTAGAA
GCGACTGTCATGTTCTTTTAATTGGTGATCCTGGTTTAGGTGTGACTTACTTTTTATAAT
TCTATCATTTTTAATAAACTAATTAATTATTGTTTTTACTCAAAAAGGTAAATCTTAGTT
ATTGAAATTTTTAGCCAATATCACTACTAGATCAATATATACATGTGGAAGCAGCTCTTC
TAACGCTGGTTTGACTGTTACAGTTACAAAAGATCCAGTTACTGGTGAAAGTACGCTCGA
AGCTGGTGCTCTTATTTTGAGTGATTAAGGTGTTTGTTGTATTGATGAATTTGATAAAAT
GTCTGCTGATCATTATGTCTTGTTAGAAGCTATGGAACAATAAACAGTTTCTCTAGCTAA
AAGTGGTGTCCTTTGCTCACTTTAATCAAGAGCAACTATTATAGCTTCAGCTAATCCAAA
AGAAGGACATTATAAGTAATTTAATGTTTTTTATCAATAAAAAATAACACATTATTTAAA
ATAAAAAGTAAATCAAAATAAATCAAGGATAATATTAAAATTAATAACGCAATTCTATCT
AGATTTGATTTAATTTTCCTTCTATTAGATACTCCTGATCCAATGAGAGATTAAAAATTA
TCAGAACATATTATGAAAGTAATTTTTAAAAAATTAATTTTTATTTTATTAAATTAAATT
AAAAATATTTTTGTTAAAGGGTTTTTTTTTAATTTTAAAATTATTTAATTCAATTCTTTA
CAATTTTTTAAAGATTATATTCTTTATTTTGAATAATGAATAAATTAATCAACAGCTGCA
TTCAAGAAAAAGAAAGAAAGATGAAATGGGATAGTTTGTTTAGAAATAGCCTTAATACAT
GCAAGATACTGAATACAGTTCTTTGACAGAAAAATTATAAGCTGAGTGTGCAGAAGTTAC
TGAAAATCTAATTCTCTCTCCTGCTATAATGAGAAAATATATTTAGTATGTGAAGAAATT
TGTTCAGCCAGTGTAAATAATTTATTTAGTTTTGATATTTAAATAAATCCTTTAAAATAA
TAAATAAATATTTAGACTTAGTAGAGAAGCTGCTGAAATTATAAAGGAATTTTATTTAAC
TTTGAGAGAATCACATTTTAATACTTCATCTATTCCAATTACAAACAGACAACTTGAGTC
TCTAGTAAGACTTTCATAAGCCCGTGCAAAAATAGAATGCAGAGATATAGTGACGAAAAA
GGATGCTCTTGTATTTTGATTTTCGAATAATTTAGACCAAATAAATTTATTGACATCAAA
TTTATTTAAAAATTAGGAAGTTGTTGAGCTGATGTAAGAAAGTTTATTTGATTCTCTTGA
AGATCTAAACTACGCTCGTGGAGCAGGTGGCACTTCTTTATAAGTTAATAAGGGTTTGAA
AAATATAAACCCAAACAATATAGGAAGTCTTAGTGTGATGAAATAAACAAAGGTCTTCTT
AGAAAGATTATAATAAGAAGCATCAATTAAAGGTTCATATTAATTCTCCTATAACGATTT
AACAACTATAGCAAAGAGCATTAACATGAATGTTGGAGATTTCAGTGAGTTTATTTCAAA
GCTTAATCATTAATCTATGCTTATTTTTAGAGGTAACAAAAACTATGAATTGGCAGCAAA
AAGAAATTACTGA

>TTHERM_01031060(protein)
MSSFKRESDFYYKSPGRLTHPKKNNESSLSIIQPEMNNNSNFDHTLLLEKWKDYFQDDCK
TFYDNDPRHVMLLSFFECYRLYQQFKDIIEWTNLKRNDLSEAYVDFIKLKNFDDETCKEA
ELFKQEIEKDVNDTINSLSLALDCVRVHLLGQKRKKVIVRLYNYDQSVQLRDIKANIINK
YLQVKGVVLKTSPVQVMINEMTFQCLDCKQNQVIKFLYGIYSQPTKCLNTKCKGTKFNPD
KTRAKASLYQRIKLQEIEEDDKGSGRVPRTLECELRDNLVNTTINGDIVTVSGLLRTEAA
DLSQQGKKTIGLQSNVMDVNCLTNSKNENKLLNEDEEEFSEEDIIMAQTLSDDPRVFPRL
VKSVCPTIFGHELVKAGLLLSILGGAPVNELQGISNPFADDNKISFRSDCHVLLIGDPGL
GKSQLLKFLANITTRSIYTCGSSSSNAGLTVTVTKDPVTGESTLEAGALILSDQGVCCID
EFDKMSADHYVLLEAMEQQTVSLAKSGVLCSLQSRATIIASANPKEGHYNKSKQIKDNIK
INNAILSRFDLIFLLLDTPDPMRDQKLSEHIMKLHSRKRKKDEMGQFVQKQPQYMQDTEY
SSLTEKLQAECAEVTENLILSPAIMRKYIQYVKKFVQPVLSREAAEIIKEFYLTLRESHF
NTSSIPITNRQLESLVRLSQARAKIECRDIVTKKDALEVVELMQESLFDSLEDLNYARGA
GGTSLQVNKGLKNINPNNIGSLSVMKQTKVFLERLQQEASIKGSYQFSYNDLTTIAKSIN
MNVGDFSEFISKLNHQSMLIFRGNKNYELAAKRNY