Identifiers and Description

Gene Model Identifier

TTHERM_00011230

Standard Name

AKM1 (Advancer of K+ through the cell Membrane 1)

Aliases

PreTt11729 | 1.m00777

Description

AKM1 cation channel family protein

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

Domains

  • ( PF00520 ) transporter, cation channel family
  • ( PF01465 ) GRIP domain
  • ( PF05767 ) Poxvirus virion envelope protein A14
  • ( PF07197 ) Protein of unknown function (DUF1409)
  • ( PF07885 ) Ion channel

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_02827.1 3.0001680331469735e-143
Description: cation channel family protein (327 aa)
Oxytricha Contig21657.0.g92 4.999617891954556e-16
Description: Ion channel
WormBase WBGene00012967 0.0000000000019997478866288316
Description: locus:kvs-4 status:Partially_confirmed UniProt:Q9XXD1 protein_id:CAA19530.3
DictyBase DDB_G0282291 0.0004000184047659232
Description: potA on chromosome: 3 position 5660926 to 5663954
SGD YJL093C 0.0007003012208360162
Description: TOK1 Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin

General Information

No. Gene Name(s) Paragraph Text
46 AKM1 Tetrahymena thermophilia AKM1 (Advancer of K+ through the cell Membrane) contains one identified functional domain: the ion channel family (E-value 1.8 X 10 〖10〗^(-12)). It is most closely related to Ichthyophthirius multifilis EGR28840.1, a small-conductance, calcium-activated potassium channel protein. It is likely that AKM1 has a similar conformation as this protein. AKM1 is expected to be a tetrameric potassium channel, located in the phospholipid bilayer and contains a “loop” which is involved in the selectivity of ions that may pass through the channel. Paragraph by: Makari Krause and Amanda McQuade (undergraduates), Keck Science Department, Claremont McKenna, Pitzer, and Scripps Colleges.

Associated Literature

No Data fetched for Associated Literature

Sequences 

>TTHERM_00011230(coding)
ATGGTATCTTTAATAAGATACATCGATATCAACAGAAAAGGAGAACTAATTAATTTACTA
ATGATTAATTTTTAAATCAAAAATAATTTAGAATAATCAAAAATTAATAATTTAATGTAA
AATATGAAGATAATGAGAAATCATAAACTCTATACAATACTGTGCTCAATTAATGGATTA
ATCCAATGTTGTGAAAGCTATTATTTCACAAAGTAGACTTTGACATAATAAGAAGATAAT
CTAATTATATTGCTCAATCAAAATGAAGATGCAGTCTTTTTTTTTTTAAGAATTGTATGC
TTGATATTAAGTTGTGCAAGTGTCTTTTTTTATTATAGAGAGAATAAGAAAAATTTGAAT
ATTGTTACCATTCTTATTTTACTTATTTGCACACCTCCAAGAGTGAATGCTATTGTTCAT
ATTGAAGTAGATTATCAAATAGACTCTATAATTAGCATATTTTCAACTCTCAAGTTTATT
GAAATTATCAAATATATTTTAATCAATAATGAATATTACAATAAGAAGCATTCTTTTTGG
TTTTCTTTTAAGAGTCTTAACTAGTTTAGACCTTTAATGCTAATTTCATCAATTACCCTT
CTTTTTATTTTTGTTTTCAGTTATATAATATTTGTGCTTGAACTTAACAAACAGCCTGAA
TAATTTAATTCAATATTGTAAAGTGGATATTTTGTTATTGTCGCAGTAACAACAGTCGGT
TATGGAGATCTGATACCTAAAACTTACCTTGGAAAAATATTTACTAATTTTCTATGTCTT
TCAGGTTAAGTTTTATTGAGTCTTCTAGTCATAATACTTATAAGCTTATTCAACCTTACT
GATTAAGATTAAGAAAAAATAAAAGCTTTTGAAAGACCTTATTCAGAAGATAATCAATTT
AGAATGCTTTTAGGAAGGGTTGACATACACTCAAATATATCTAAAGTTTAATAAGGAATT
TTAGATGAATTAGAATTCTTGATAGAATCATTCGAATACTAAAAACAACAATAGGTAAAT
AAATAAATAAATAAATAAATATTCTTTTTTATTATATTTAATCGATGTTTATATAAAACA
TTTTAATAAATCCTAAAATTTATAAATAGAAGCTAGCTAAAATGGTTAAGTGTTGTATAT
CTTCATAAGATTTTATATTTAAATCAGAATAATTTAAATTAATAAATTATTTTTTGGATA
ATTGATATTAAATATACTTAAAAGTAAGTTTTTTCTTTTAAAACTCAAATATTTTAAGAA
AAATAAATAAATCTTTTAAATAATTTAAATAAATTATAGCATAACCAACTAAAATTTTTT
AAATTGAGAATTAAGTTAAAGCTTGGAATAAATCCTCTTTTGTTAATTTAAATAAAATAA
AATAAAAATTGTCAATCCAATAGATAGATTGAGAAATAATATCAAAACCCAGATTAATAA
TAAATATTAGTTAACAATATTTTTTAGATATTTATTAAATAAAACTAAAACATTTAAAAA
ATTTTTTAGGTTAATAATTTTTTGTAAAAAGTAAACTCTTAAAGAATTTGA


>TTHERM_00011230(gene)
ATGGTATCTTTAATAAGATACATCGATATCAACAGAAAAGGAGAACTAATTAATTTACTA
ATGATTAATTTTTAAATCAAAAATAATTTAGAATAATCAAAAATTAATAATTTAATGTAA
AATATGAAGATAATGAGAAATCATAAACTCTATACAATACTGTGCTCAATTAATGGATTA
ATCCAATGTTGTGAAGTAAATTTTTAAAATAAATGCCTTTGTTGAACCTTACAAAAATAT
TTTGTCTCAATTTCTTACTTAATAAGTAGTTAAAAATTATTTCATACTTAAAATTGTAGA
GCTATTATTTCACAAAGTAGACTTTGACATAATAAGAAGATAATCTAATTATATTGCTCA
ATCAAAATGAAGATGCAGTCTTTTTTTTTTTAAGAATTGTATGCTTGATATTAAGTTGTG
CAAGTGTCTTTTTTTATTATAGAGAGAATAAGAAAAATTTGAATATTGTTACCATTCTTA
TTTTACTTATTTGCACACCTCCAAGAGTGAATGCTATTGTTCATATTGAAGTAGATTATC
AAATAGACTCTATAATTAGCATATTTTCAACTCTCAAGTTTATTGAAATTATCAAATATA
TTTTAATCAATAATGAATATTACAATAAGAAGCATTCTTTTTGGTTTTCTTTTAAGAGTC
TTAACTAGTTTAGACCTTTAATGCTAATTTCATCAATTACCCTTCTTTTTATTTTTGTTT
TCAGTTATATAATATTTGTGCTTGAACTTAACAAACAGCCTGAATAATTTAATTCAATAT
TGTAAAGTAAATTGCCTAAAATTATAAGTAAATATTAGAAAATCTATTTTATATATATTA
GGTGGATATTTTGTTATTGTCGCAGTAACAACAGTCGGTTATGGAGATCTGATACCTAAA
ACTTACCTTGGAAAAATATTTACTAATTTTCTATGTCTTTCAGGTTAAGTTTTATTGAGT
CTTCTAGTCATAATACTTATAAGCTTATTCAACCTTACTGATTAAGATTAAGAAAAAATA
AAAGCTTTTGAAAGACCTTATTCAGAAGATAATCAATTTAGAATGCTTTTAGGAAGGGTT
GACATACACTCAAATATATCTAAAGTTTAATAAGGAATTTTAGATGAATTAGAATTCTTG
ATAGAATCATTCGAATACTAAAAACAACAATAGGTAAATAAATAAATAAATAAATAAATA
TTCTTTTTTATTATATTTAATCGATGTTTATATAAAACATTTTAATAAATCCTAAAATTT
ATAAATAGAAGCTAGCTAAAATGGTTAAGTGTTGTATATCTTCATAAGATTTTATATTTA
AATCAGAATAATTTAAATTAATAAATTATTTTTTGGATAATTGATATTAAATATACTTAA
AAGTAAGTTTTTTCTTTTAAAACTCAAATATTTTAAGAAAAATAAATAAATCTTTTAAAT
AATTTAAATAAATTATAGCATAACCAACTAAAATTTTTTAAATTGAGAATTAAGTTAAAG
CTTGGAATAAATCCTCTTTTGTTAATTTAAATAAAATAAAATAAAAATTGTCAATCCAAT
AGATAGATTGAGAAATAATATCAAAACCCAGATTAATAATAAATATTAGTTAACAATATT
TTTTAGATATTTATTAAATAAAACTAAAACATTTAAAAAATTTTTTAGGTTAATAATTTT
TTGTAAAAAGTAAACTCTTAAAGAATTTGA


>TTHERM_00011230(protein)
MVSLIRYIDINRKGELINLLMINFQIKNNLEQSKINNLMQNMKIMRNHKLYTILCSINGL
IQCCESYYFTKQTLTQQEDNLIILLNQNEDAVFFFLRIVCLILSCASVFFYYRENKKNLN
IVTILILLICTPPRVNAIVHIEVDYQIDSIISIFSTLKFIEIIKYILINNEYYNKKHSFW
FSFKSLNQFRPLMLISSITLLFIFVFSYIIFVLELNKQPEQFNSILQSGYFVIVAVTTVG
YGDLIPKTYLGKIFTNFLCLSGQVLLSLLVIILISLFNLTDQDQEKIKAFERPYSEDNQF
RMLLGRVDIHSNISKVQQGILDELEFLIESFEYQKQQQVNKQINKQIFFFIIFNRCLYKT
FQQILKFINRSQLKWLSVVYLHKILYLNQNNLNQQIIFWIIDIKYTQKQVFSFKTQIFQE
KQINLLNNLNKLQHNQLKFFKLRIKLKLGINPLLLIQIKQNKNCQSNRQIEKQYQNPDQQ
QILVNNIFQIFIKQNQNIQKIFQVNNFLQKVNSQRI