Identifiers and Description

Gene Model Identifier

TTHERM_00036960

Standard Name

VPS41 (Vacuolar Protein Sorting 4-1)

Aliases

PreTt14431 | 2.m02094 | 3825.m02804

Description

vacuolar protein sorting-associated protein 4b; VPS4-like ATPase- AAA family protein; associated with vesicle formation and programmed nuclear death; localizes to cytoplasm and oral apparatus during growth and to parental macronucleus during conjugation

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IDA) | GO:0005737
• macronucleus (IDA) | GO:0031039
• oral apparatus (IDA) | GO:0031912

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_00957.1	9.997093137033517e-262
	Description: ATPase, AAA family protein (444 aa)
Oxytricha	Contig13722.0.g102	3.0011260078469234e-135
	Description: ATPase family associated with various cellular activities (AAA)
SGD	YPR173C	9.001601097193671e-134
	Description: VPS4 AAA-ATPase involved in multivesicular body (MVB) protein sorting, ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism
WormBase	WBGene00021334	1.9999788875029746e-125
	Description: locus:vps-4 status:Confirmed UniProt:Q9BL83 protein_id:CCD68056.1
DictyBase	DDB_G0284347	9.996261361959507e-120
	Description: vps4 on chromosome: 4 position 1865073 to 1866634
Stentor Coeruleus	SteCoe_25506	1.733141042341547e-58
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00036960(coding)
ATGTTTTACGGAGGTAATAACGCTCCCTCATTTAAGTTAGATAATACTTAAATTCGTAAT
GAAACATAGTACCTGATTGAGAAAGGTAGAAGATCTTTCAATGAAGGTGATACAATTGAA
GAAAAGGATAAGGGTATTTCAACCTTTTTACAAGGTTTAAAGAAGTTAGAACTATGGATA
TAAAGAGAAACTGATACTTTAATTCTAAATACTTTAAAAACCTAATACCAAAATAACTAT
AAAGAAGTAGAAACTATGCTTACAAAATTAGAATAAATTAAAAAAAATGGAAACTAGCCT
ATGGCAATAGCATAAGGCGGCGGCGGTGGTAACAACAATAGTAACAAAGATGAAAACACT
AAATTTAAGGAAGCTTTGTAAGAAACAATTGTGCCCGAAAAACCTAACATAAAATGGGAT
GATATTGCTGGTTTAGTGAAGGCTAAGGAATCCTTAAAAGAAGCAGTCATTCTTCCAATT
AGATTCCCTGAAATATTTAAAGGTGCTCGTAAGCCATGGAAAGGTATCCTTCTTTATGGA
CCTCCAGGTACTGGTAAAACTTATTTAGCTAAAGCTTGTGCTACAGAAACTGAAGGTACT
TTCTTTTCAGTATCCTCTGCAGATCTTGTCAGCAAATATGTTGGTGAATCAGAAAAATTA
ATTAAGAACTTATTTGCTTTAGCTAGAGAGAAAAAGCCTTCTATTATATTTATTGATGAA
GTAGACAGTTTATGTGGTAATAGAAGTGACGGAGAAAATGATGCTTCAAGAAGAGTAAAA
ACAGAGTTTTTGGTTTAGATGCAAGGTGTTGGTAATGATGATTAAGGTGTTTTGGTACTT
GGAGCAACCAATTTACCATGGGCTCTCGATCCTGCTATTAGAAGAAGATTTGAAAAAAGA
ATCTACATCCCCTTGCCTGACTAACCCGCCAGAAAATTCTTGCTCAAACATAACCTTAAA
AATACTCCAAACACTCTTAAAGAAGAAGATTTTGAAAGATTATCCTAATTAACAGACGGA
TTCTCAGGAGCTGATATGTCTATATTTGTAAGAGATGCAGTACTAGAACCAGTTAGAAGA
TTATAGATTGCAACTAAATTCAAAAAGTTACCAGGAGACAAATACATGCCTGTAGAAGAT
AATGCTTCAGGTCCTGATATTGTTAACCTTAACTATTTAAGCTTAAATCAGTAATAGCTT
GAGCTTCCATAAATATCTGCACAAGATTTTGAAATCGCCATTAAAAAAGCCAAAGGTACT
GTTGGAAAAGATTAGCTCAAAGATTATGAAAAGTGGACTACTGAATTTGGTCAAGATGGT
TGA

>TTHERM_00036960(gene)
ATGTTTTACGGAGGTAATAACGCTCCCTCATTTAAGTTAGATAATACTTAAATTCGTAAT
GAAACATAGTACCTGATTGAGAAAGGTAGAAGATCTTTCAATGAAGGTGATACAATTGAA
GAAAAGGATAAGGGTATTTCAACCTTTTTACAAGGTTTAAAGAAGTTAGAACTATGGATA
TAAAGTAATTTATTTAGATTTACAAATTCGAATCGTTTAAGCTTAAAAAAATAACGCGAA
TCAATTGAAAAATTAACCATTTTTTATTATAATTAACAGGAGAAACTGATACTTTAATTC
TAAATACTTTAAAAACCTAATACCAAAATAACTATAAAGAAGTAGAAACTATGCTTACAA
AATTAGAATAAATTAAAAAAAATGGAAACTAGCCTATGGCAATAGCATAAGGCGGCGGCG
GTGGTAACAAGTAAAATATATTGCAAAATTAGCTAAGTTTAAATATAAAATTTGGTTTTA
AAATAAAATGAAAGCTTATTCTTTAAATTATTTATAGTGGCATTAATTCTTTCATGTATT
ATCACTTAGATTAATTTTATTTTATCTTAAATAGCAATAGTAACAAAGATGAAAACACTA
AATTTAAGGAAGCTTTGTAAGAAACAATTGTGCCCGAAAAACCTAACATAAAATGGGATG
ATATTGCTGGTTTAGTGAAGGCTAAGGAATCCTTAAAAGAAGCAGTCATTCTTCCAATTA
GATTCCCTGAAATATTTAAAGGTGCTCGTAAGCCATGGAAAGGTATCCTTCTTTATGGAC
CTCCAGGTACTGGTAAAACTTATTTAGCTAAAGCTTGTGCTACAGAAACTGAAGGTACTT
TCTTTTCAGTATCCTCTGCAGATCTTGTCAGCAAATATGTTGGTGAATCAGAAAAGTAAT
TTAATTTAATTTAATTTACATTCATTTTCTTTCAGCAAAAAAAACATTATCAATATTTGA
TTAATTAGTGTCTTTAATTATTAAGACAAAATCAACTCTTTAAAAATTTATTAGAATTTC
ATGCTTCACTTTCAAAATATCTTTTGATTGTAATATAAATCAGTCAAAATGAATGAAAAA
ATTCATTCATTCATTCATTCTTTATTTATTATTTTTCTAAAATTTGAAAGTTCATTATTT
GCATGAAAACAAATAAGTTATTATAGATAAAATTAATTTGGTTTATTTCACAATATTTCT
GATCGCATCAATAGGAAATATTGATCAGCATTTGAATATTTATTTATTTAATAAATATCT
CATTTTTCTTTTAAGATTAGAAAATATTTTTACAGTCTATCAAGAAATATAAAAATTTTT
TGAATGCATTTTCATAGGATAAATATATTTTTAAAATAAAAAATAATAGATTAATTAAGA
ACTTATTTGCTTTAGCTAGAGAGAAAAAGCCTTCTATTATATTTATTGATGAAGTAGACA
GTTTATGTGGTAATAGAAGTGACGGAGAAAATGATGCTTCAAGAAGAGTAAAAACAGAGT
TTTTGGTTTAGATGCAAGGTGTTGGTAATGATGATTAAGGTGTTTTGGTACTTGGAGCAA
CCAATTTACCATGGGCTCTCGATCCTGCTATTAGAAGAAGATTTGAAAAAAGAATCTACA
TCCCCTTGCCTGACTAACCCGCCAGAAAATTCTTGCTCAAACATAACCTTAAAAATACTC
CAAACACTCTTAAAGAAGAAGATTTTGAAAGATTATCCTAATTAACAGACGGGTAAAATG
ATTATAAAAGAAATATACAGAATTTTAACATGTTAATTAAAAACAATATATAGATTCTCA
GGAGCTGATATGTCTATATTTGTAAGAGATGCAGTACTAGAACCAGTTAGAAGATTATAG
ATTGCAACTAAATTCAAAAAGTTACCAGGAGACAAATACATGCCTGTAGAAGATAATGCT
TCAGGTCCTGATATTGTTAACCTTAACTATTTAAGCTTAAATCAGTAATAGCTTGAGCTT
CCATAAATATCTGCAGTAAAATTTTTTATTTTTTTATTTTATATTTTTAATAAATAAATT
CTATTTAATAATAAAGCAAGATTTTGAAATCGCCATTAAAAAAGCCAAAGGTACTGTTGG
AAAAGATTAGCTCAAAGATTATGAAAAGTGGACTACTGAATTTGGTCAAGATGGTTGA

>TTHERM_00036960(protein)
MFYGGNNAPSFKLDNTQIRNETQYLIEKGRRSFNEGDTIEEKDKGISTFLQGLKKLELWI
QRETDTLILNTLKTQYQNNYKEVETMLTKLEQIKKNGNQPMAIAQGGGGGNNNSNKDENT
KFKEALQETIVPEKPNIKWDDIAGLVKAKESLKEAVILPIRFPEIFKGARKPWKGILLYG
PPGTGKTYLAKACATETEGTFFSVSSADLVSKYVGESEKLIKNLFALAREKKPSIIFIDE
VDSLCGNRSDGENDASRRVKTEFLVQMQGVGNDDQGVLVLGATNLPWALDPAIRRRFEKR
IYIPLPDQPARKFLLKHNLKNTPNTLKEEDFERLSQLTDGFSGADMSIFVRDAVLEPVRR
LQIATKFKKLPGDKYMPVEDNASGPDIVNLNYLSLNQQQLELPQISAQDFEIAIKKAKGT
VGKDQLKDYEKWTTEFGQDG