Identifiers and Description

Gene Model Identifier

TTHERM_00058820

Standard Name

AXE1 (Ankyrin/histone H3 methyl transferase and EXosome 3-5 exoribonuclease 1)

Aliases

PreTt13067 | 4.m00466 | 3707.m00111

Description

AXE1 3-prime-5-prime exonuclease; Fusion of ankyrin/histone H3 methyl transferase and exosome 3-5 exoribonuclease; 3'-5' exonuclease family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Molecular Function

• rhamnulokinase activity (IEA) | GO:0008993

Biological Process

• detection of virus (IEA) | GO:0009597
• protein import into peroxisome matrix, receptor recycling (IEA) | GO:0016562
• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00023 ) Ankyrin repeat
• ( PF01612 ) 3'-5' exonuclease
• ( PF07620 ) SLEI
• ( PF08128 ) Double glycine cleavage site bacteriolysin
• ( TIGR00255 ) conserved hypothetical protein TIGR00255

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_01987.1	9.997093137033517e-262
	Description: 3-5 exonuclease (1059 aa)
Oxytricha	Contig6366.0.g39	8.001824328206442e-49
	Description: Ankyrin repeats (3 copies)
DictyBase	DDB_G0271572	7.999528511121947e-28
	Description: exosc10 on chromosome: 2 position 601251 to 605014
WormBase	WBGene00000796	4.0013320766793207e-25
	Description: locus:crn-3 status:Confirmed UniProt:G5EBX6 protein_id:CAA90108.1
SGD	YOR001W	4.0006511639687014e-23
	Description: RRP6 Nuclear exosome exonuclease component; has 3-5 exonuclease activity; involved in RNA processing, maturation, surveillance, degradation, tethering, and export; has similarity to E. coli RNase D and to human PM-Sc1 100 (EXOSC10); mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay
Stentor Coeruleus	SteCoe_12809	2.8625185805493937e-20
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00058820(coding)
ATGTATAAAACAGAAGTTAATTTGCTTAATAAAATATGCAAAACAGATTATTTTAGTAAA
TTAAATACTAAACTTGACAATCTGGTTGATTATAATATCATTTTTAATGAATACTGCGAT
TTTTTAATGATTGAGAAATACTCCCTACTTTTAAATGAGCCTAGAATAAATTAATTTAAA
TATAATCAATTTTATTATGATGAAGTGAATCTCAGACAGCAGCTATTTTCCTAATTTTAA
CTAAGTCGAATTAACCAAACAATAAAGATTTCTAATATACTTGTTCAACCATATAGTAAC
AAGGGAACTTATCAATTAGTAAAAGACTTAGACTCTGAATTAGAAGCATAGGCTTATTTT
TTAGATAATACAGAATATTCTTTTTTAGATGTGATAGTCTTTTCTTCTTTACAAAAATGT
AGAATATGGCCAAAGCTCTACAAAGATGGGAAGAAGTCAAAAAAGGAATTACCTTAGCTT
ATTGATTGGTATAAAGTATTTATGAATACATACAAACATGAAATTGAATACTAATTTGAT
CCCAATATTGTGACAAGTAAATACTAAAAAAGACTAGAAATATAAAAGAAAGAAAAAAGA
TTAGATAAAAAATTAATTGAAGCTGTTTAAAGTAAATAATATGATTTAATCCGGAGTCTC
ATAGAAGAAGGCTCAGATATAGAAAGCATAGAGTAGTAGATGTACAAAAAACCAGCTCAT
ATAGCATGTGAACTAGGAGATATAGAGCTTTGTAGGTTTATAGACTAGTTTGGGTGTGAT
TGGGAATCATTAGATAATGAAGAATAGACTCCTATATTCTATGCAGTTACGAGTGGAAAT
TTAGAAGTTGTAAAATTTCTCATTGAAGAAAAAAATGTCAATCATTAACATAAAGAATTT
TAAGATAGGACTCCATTTTATTTGGCTTGTTTCTTAGGAAATATGCCTATTATTGAATAT
TTATATGAAAAAGGTGTGAATATTAATGAGCCATCAAAGCTCAAGCGCTGTGCACTAAGC
AAGGCTTGCTATTTAGGGCATGTAGAAGTAGTAAAATTCCTCGTATCGAAGCCTGAAACT
GATATTACTATGTAAGATTCTAAAGGTAGAACGGGGATGCATAATGCAGCATGGGGAATT
GAAGGTGGGAAAGAAGGAAAGAGGAGGGGAACTTTGAAACTCCCAGACTCTCCTTAATCT
ATAGAAATACTTCATGATTATGGTCATCCTATTGATTTTTAAGATTTTGAAGGAAACACT
CCTTTACTTAGTGCAGCATCCAGCGATGCAAGGGAATCCTTAAGAGTACTAATAAATAGA
GGCGCAAATAGAAATATTAGGAATTTTTATGGAGAAACTCCAGTCTTTTTAGCAGCTAAA
TATGGTCATACTGAGATCTTAAAAACCTTAATTAATGAATATAAATGTGATTGGGAAATG
AGAGATATTAGAAACACTACTCCTTGCGAAATAGCTGCTATAAACTAGAAATATGAATGT
TTTGATATACTTTTAAATTTAGAAATTCAAAACAATACAGTTAATGTTGAGAGTTTCATA
AAAAAAATCAATGATGACTACATCACTCATGAAGAATAACTTAAAATATTTGAATTGTAC
AATAGTAAAGTAGATATTAAGAATCGTATTTAAGATATAGAAAGTGTAATCTCTTTTTTG
ACTAATTGTACTAATCCATAATTAATGCTTAGAATTTAAGAAATAATATTAGATAGATTA
AATCCTTCTCACATTAAACAATTTTTCATTAACTTAGCTGATAATGGCAAGTATGATACA
GCATTTTAAATCTTAGAGACATTTGAATTAAAATATAAAGCTTCAGATAATCAAATTTAG
GGAATTCTGTTTGATCCATAAGAAATTTATAATTTTATTATTAAGGGAGTTAGTGCCACT
GATGAAACAATAAGTAAACTTCTATTTAAGGTTAATAGTGATTGGATCAATTACACAGAT
GATTCAACTAAAAATAACTTTTTACATATATTATGTGAATAGAGGAGAATGAAAATAATA
GTAGATTTAATTACCATAATCAAAGAAAAGAGCATTAATCCTGCTTACTCTTTTACATCT
AACATATATTTGCTAAATAATAATTAGTTTTACACATAGGATTTTGTTAGAAAATACTTA
AATGCAGTCAACTCTTAAAACTTAAATTCGTTAGATATATGTTTACTTTCAAAAGCAAAC
GACATTCATTTGATCATAGATAATTTTATTAGGAGCTTTCTTCATGAAGAACCTTCTTAT
CATTATGTTATACCAAGTTATGACTTTGAAATGATTTCCCAAAGAGACACAGATGTAAAA
TAAATTATTACACTTGAAGCCAATATATTTTTGTCTCAAACAATTCACTTATTTATATTT
TATTTTAAAATAAATTAGCATGCTTTAATCGGTGAATTAGAAGAAGAAGCGAAAAAGCTC
TAAGAACAAATCAAATAAAAAAGTGGAGATCTTTAGCATTTGAATTGTTATTCTTTCTTA
GACGACTTAAGTGTAATTGATTAGTAAAAAGTGACAGTTGAGGACAATTCAGAATAAAAC
CAGAACATTGAAAAATTATATCCAAATAGAAAGTTGTATTTTATAAATTAGATTGATTCA
GATGAATCAAGAATTCTTAAGGAAGAAATCGAAAAAAACAGTATTTTTGGTATTGACCTT
GAGTATTACTCTGAAAATAAAGATAAAAATCTAGGATTTGTATGTACTATTCAGATATCT
ACAGTTAATATGGATTTTATGATAGATGCTATGGCATTAAGAAATTAGATAAATTAATTA
CTAAATAAATCTCTCTTTTTAAATAAAACAAAAATTAAAATTTTGCATGGCTGCGAAAAC
GATATCAAGTGGCTTAAAAACGACTTCGATATTGATATAGTTAATCTATTTGATACAATG
TTTGCAGAAATGATTATTAAAAACAAGCAGCAATCTTACTCTCTCAAAAATTTATCTTAA
GACTATCTAGGTGTAGAACTAGATAAATCATATTAAATTTCAGATTGGAGAATTAGACCT
CTTCCAACTCCAATGATGAATTATGCAAGAGTCGATTCTTTTATTCTGTTGAGACTATTC
CCCATCATGAAATAAATGCTAACATCCAAAAATTTGTTAAATCAAATGTTCCTAAAGTGC
CTTCTTTTCATAATTCGTTAAAGCAATTCCAAAAAAACACAACAATTATAATAATGCTAG
TAAAATAATAATAAGTGA

>TTHERM_00058820(gene)
ATGTATAAAACAGAAGTTAATTTGCTTAATAAAATATGCAAAACAGATTATTTTAGTAAA
TTAAATACTAAACTTGACAATCTGGTTGATTATAATATCATTTTTAATGAATACTGCGAT
TTTTTAATGATTGAGAAATACTCCCTACTTTTAAATGAGCCTAGAATAAATTAATTTAAA
TATAATCAATTTTATTATGATGAAGTGAATCTCAGACAGCAGCTATTTTCCTAATTTTAA
CTAAGTCGAATTAACCAAACAATAAAGATTTCTAATATACTTGTTCAACCATATAGTAAC
AAGGGAACTTATCAATTAGTAAAAGACTTAGACTCTGAATTAGAAGCATAGGCTTATTTT
TTAGATAATACAGAATATTCTTTTTTAGATGTGATAGTCTTTTCTTCTTTACAAAAATGT
AGAATATGGTACAATTTATTGATTTAAATGAATTAAATTTAGCAATCCTTTTTACCATAC
AATAAATAACTTTATTATCAAAACAAAATCAGGCCAAAGCTCTACAAAGATGGGAAGAAG
TCAAAAAAGGAATTACCTTAGCTTATTGATTGGTATAAAGTATTTATGAATACATACAAA
CATGAAATTGAATACTAATTTGATCCCAATATTGTGACAAGTAAATACTAAAAAAGACTA
GAAATATAAAAGAAAGAAAAAAGATTAGATAAAAAATTAATTGAAGCTGTTTAAAGTAAA
TAATATGATTTAATCCGGAGTCTCATAGAAGAAGGCTCAGATATAGAAAGCATAGAGTAG
TAGATGTACAAAAAACCAGCTCATATAGCATGTGAACTAGGAGATATAGAGCTTTGTAGG
TTTATAGACTAGTTTGGGTGTGATTGGGAATCATTAGATAATGAAGAATAGACTCCTATA
TTCTATGCAGTTACGAGTGGAAATTTAGAAGTTGTAAAATTTCTCATTGAAGAAAAAAAT
GTCAATCATTAACATAAAGAATTTTAAGATAGGACTCCATTTTATTTGGCTTGTTTCTTA
GGAAATATGCCTATTATTGAATATTTATATGAAAAAGGTGTGAATATTAATGAGCCATCA
AAGCTCAAGCGCTGTGCACTAAGCAAGGCTTGCTATTTAGGGCATGTAGAAGTAGTAAAA
TTCCTCGTATCGAAGCCTGAAACTGATATTACTATGTAAGATTCTAAAGGTAGAACGGGG
ATGCATAATGCAGCATGGGGAATTGAAGGTGGGAAAGAAGGAAAGAGGAGGGGAACTTTG
AAACTCCCAGACTCTCCTTAATCTATAGAAATACTTCATGATTATGGTAAACTTATGGTA
TTATGTAAGACTTTTTAAAAAAAAAGAATTATTTTTATTAAAAAAAGGTCATCCTATTGA
TTTTTAAGATTTTGAAGGAAACACTCCTTTACTTAGTGCAGCATCCAGCGATGCAAGGGA
ATCCTTAAGAGTACTAATAAATAGAGGCGCAAATAGAAATATTAGGAATTTTTATGGAGA
AACTCCAGTCTTTTTAGCAGCTAAATATGGTCATACTGAGATCTTAAAAACCTTAATTAA
TGAATATAAATGTGATTGGGAAATGAGAGATATTAGAAACACTACTCCTTGCGAAATAGC
TGCTATAAACTAGAAATATGAATGTTTTGATATACTTTTAAATTTAGAAATTCAAAACAA
TACAGTTAATGTTGAGAGTTTCATAAAAAAAATCAATGATGACTACATCACTCATGAAGA
ATAACTTAAAATATTTGAATTGTACAATAGTAAAGTAGATATTAAGAATCGTATTTAAGA
TATAGAAAGTGTAATCTCTTTTTTGACTAATTGTACTAATCCATAATTAATGCTTAGAAT
TTAAGAAATAATATTAGATAGATTAAATCCTTCTCACATTAAACAATTTTTCATTAACTT
AGCTGATAATGGCAAGTATGATACAGCATTTTAAATCTTAGAGACATTTGAATTAAAATA
TAAAGCTTCAGATAATCAAATTTAGGGAATTCTGTTTGATCCATAAGAAATTTATAATTT
TATTATTAAGGGAGTTAGTGCCACTGATGAAACAATAAGTAAACTTCTATTTAAGGTTAA
TAGTGATTGGATCAATTACACAGATGATTCAACTAAAAATAACTTTTTACATATATTATG
TGAATAGAGGAGAATGAAAATAATAGTAGATTTAATTACCATAATCAAAGAAAAGAGCAT
TAATCCTGCTTACTCTTTTACATCTAACATATATTTGCTAAATAATAATTAGTTTTACAC
ATAGGATTTTGTTAGAAAATACTTAAATGCAGTCAACTCTTAAAACTTAAATTCGTTAGA
TATATGTTTACTTTCAAAAGCAAACGACATTCATTTGATCATAGATAATTTTATTAGGAG
CTTTCTTCATGAAGAACCTTCTTATCATTATGTTATACCAAGTTATGACTTTGAAATGAT
TTCCCAAAGAGACACAGATGTAAAATAAATTATTACACTTGAAGCCAATATATTTTTGTC
TCAAACAATTCACTTATTTATATTTTATTTTAAAATAAATTAGCATGCTTTAATCGGTGA
ATTAGAAGAAGAAGCGAAAAAGCTCTAAGAACAAATCAAATAAAAAAGTGGAGATCTTTA
GCATTTGAATTGTTATTCTTTCTTAGACGACTTAAGTGTAATTGATTAGTAAAAAGTGAC
AGTTGAGGACAATTCAGAATAAAACCAGAACATTGAAAAATTATATCCAAATAGAAAGTT
GTATTTTATAAATTAGATTGATTCAGATGAATCAAGAATTCTTAAGGAAGAAATCGAAAA
AAACAGTATTTTTGGTATTGACCTTGAGTATTACTCTGAAAATAAAGATAAAAATCTAGG
ATTTGTATGTACTATTCAGATATCTACAGTTAATATGGATTTTATGATAGATGCTATGGC
ATTAAGAAATTAGATAAATTAATTACTAAATAAATCTCTCTTTTTAAATAAAACAAAAAT
TAAAATTTTGCATGGCTGCGAAAACGATATCAAGTGGCTTAAAAACGACTTCGATATTGA
TATAGTTAATCTATTTGATACAATGTTTGCAGAAATGATTATTAAAAACAAGCAGCAATC
TTACTCTCTCAAAAATTTATCTTAAGACTATCTAGGTGTAGAACTAGATAAATCATATTA
AATTTCAGATTGGAGAATTAGACCTCTTCCAACTCCAATGATGAATTATGCAAGAGTCGA
TTCTTTTATTCTGTTGAGACTATTCCCCATCATGAAATAAATGCTAACATCCAAAAATTT
GTTAAATCAAATGTTCCTAAAGTGCCTTCTTTTCATAATTCGTTAAAGCAATTCCAAAAA
AACACAACAATTATAATAATGCTAGTAAAATAATAATAAGTGA

>TTHERM_00058820(protein)
MYKTEVNLLNKICKTDYFSKLNTKLDNLVDYNIIFNEYCDFLMIEKYSLLLNEPRINQFK
YNQFYYDEVNLRQQLFSQFQLSRINQTIKISNILVQPYSNKGTYQLVKDLDSELEAQAYF
LDNTEYSFLDVIVFSSLQKCRIWPKLYKDGKKSKKELPQLIDWYKVFMNTYKHEIEYQFD
PNIVTSKYQKRLEIQKKEKRLDKKLIEAVQSKQYDLIRSLIEEGSDIESIEQQMYKKPAH
IACELGDIELCRFIDQFGCDWESLDNEEQTPIFYAVTSGNLEVVKFLIEEKNVNHQHKEF
QDRTPFYLACFLGNMPIIEYLYEKGVNINEPSKLKRCALSKACYLGHVEVVKFLVSKPET
DITMQDSKGRTGMHNAAWGIEGGKEGKRRGTLKLPDSPQSIEILHDYGHPIDFQDFEGNT
PLLSAASSDARESLRVLINRGANRNIRNFYGETPVFLAAKYGHTEILKTLINEYKCDWEM
RDIRNTTPCEIAAINQKYECFDILLNLEIQNNTVNVESFIKKINDDYITHEEQLKIFELY
NSKVDIKNRIQDIESVISFLTNCTNPQLMLRIQEIILDRLNPSHIKQFFINLADNGKYDT
AFQILETFELKYKASDNQIQGILFDPQEIYNFIIKGVSATDETISKLLFKVNSDWINYTD
DSTKNNFLHILCEQRRMKIIVDLITIIKEKSINPAYSFTSNIYLLNNNQFYTQDFVRKYL
NAVNSQNLNSLDICLLSKANDIHLIIDNFIRSFLHEEPSYHYVIPSYDFEMISQRDTDVK
QIITLEANIFLSQTIHLFIFYFKINQHALIGELEEEAKKLQEQIKQKSGDLQHLNCYSFL
DDLSVIDQQKVTVEDNSEQNQNIEKLYPNRKLYFINQIDSDESRILKEEIEKNSIFGIDL
EYYSENKDKNLGFVCTIQISTVNMDFMIDAMALRNQINQLLNKSLFLNKTKIKILHGCEN
DIKWLKNDFDIDIVNLFDTMFAEMIIKNKQQSYSLKNLSQDYLGVELDKSYQISDWRIRP
LPTPMMNYARVDSFILLRLFPIMKQMLTSKNLLNQMFLKCLLFIIRQSNSKKTQQLQQCQ
QNNNK