Identifiers and Description

Gene Model Identifier

TTHERM_00077090

Standard Name

PCP4 (PARP Correlated Protein 4)

Aliases

PreTt10055 | 5.m00406 | 3828.m01316 | PZN1

Description

Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger family protein putative. Vertebrate PARPs contain PADR and zinc finger (zf)–PARP domains. None of the Tetrahymena putative PARPs carry these domains. Instead, Tetrahymena has at least six additional proteins carrying PADR1 and zf–PARP domains(Kanwal Ashraf et al., 2019)

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Molecular Function

Domains

  • ( PF00645 ) Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger
  • ( PF02037 ) SAP domain
  • ( PF08063 ) PADR1 (NUC008) domain
  • ( TIGR01634 ) phage tail protein I

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_07117.1 4.001113299181986e-136
Description: hypothetical protein (232 aa)
DictyBase DDB_G0291872 0.0005997485943342685
Description: DDB_G0291872 on chromosome: 6 position 855161 to 857960
SGD YMR306W 0.0005997485943342685
Description: FKS3 Protein involved in spore wall assembly, has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:30796450: Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ):
  2. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences 

>TTHERM_00077090(coding)
ATGACAGATTTTAAGTCCTTTTATTACGAGTGCTATTGTGCTGAATTAGCTAAGAGCAAT
AAATCAGAATGCAAAGGATGCTAAAAAACTATTGATCAAGGAACTTTGAGAATTGGCCAT
ACAGTTTATTTTGATGAGGAACACACTCATATTAACAAAAAGTGGTACCATCCAAGTTGC
TTAACACTGCCTGAAAAATTCAAAAATCTCAAAGTTTGGGACATTTAGGACATAGATGAA
CTAGATGAAAAATATCATAAGGAAATTAGAGATGCTCTCAAAATATAATAAGGTGATAAA
AATAAAAGAGTAAAGCATCTCCCAAAAGTTGTTGTCCGTTAACACAGACCAGTAGAAAAA
GTTGAGTAACAAAAAACATTAACAAAGGCTCAATGGAAGGAATACTAATCATACAGGAAA
TTGTTCGAGAAAAAAACAGTGAAACAATTATAAGAATTGTTAACTAAAAATAATGCTTCA
GTAAGTGGAGCTAAGGAATAACTAGTTTATAGATGTGCACTTTCTAAGGTATTAGGCATT
CAGCCTAATTGTCCTTCTTGTGGTGGGTAAAATCTCAGATTCTACTTTGCTGATGGCTAA
TATTATTGCCCTGGATATCTTGATGATACCGATTGGGTTAATTGTAAAAACTGGTTCGAT
TTAGATGAAGTAGAAAGAACCAAATGGGTTGATTGA


>TTHERM_00077090(gene)
ATGACAGATTTTAAGTCCTTTTATTACGAGTGCTATTGTGCTGAATTAGCTAAGAGCAAT
AAATCAGAATGCAAAGGATGCTAAAAAACTATTGATCAAGGAACTTTGAGAATTGGCCAT
ACAGTTTATTTTGATGAGGAACACACTCATATTAACAAAAAGTGGTACCATCCAAGTTGC
TTAACACTGCCTGAAAAATTCAAAAATCTCAAAGTTTGGGACATTTAGGACATAGATGAA
CTAGATGAAAAATATCATAAGGAAATTAGAGATGCTCTCAAAATATAATAAGGTGATAAA
AATAAAAGAGTAAAGCATCTCCCAAAAGTTGTTGTCCGTTAACACAGACCAGTAGAAAAA
GTTGAGTAACAAAAAACATTAACAAAGGCTCAATGGAAGGAATACTAATCATACAGGAAA
TTGTTCGAGAAAAAAACAGTGAAACAATTATAAGAATTGTTAACTAAAAATAATGCTTCA
GTAAGTGGAGCTAAGGAATAACTAGTTTATAGATGTGCACTTTCTAAGGTATTAGGCATT
CAGCCTAATTGTCCTTCTTGTGGTGGGTAAAATCTCAGATTCTACTTTGCTGATGGCTAA
TATTATTGCCCTGGATATCTTGATGATACCGATTGGGTTAATTGTAAAAACTGGTTCGAT
TTAGATGAAGTAGAAAGAACCAAATGGGTTGATTGA


>TTHERM_00077090(protein)
MTDFKSFYYECYCAELAKSNKSECKGCQKTIDQGTLRIGHTVYFDEEHTHINKKWYHPSC
LTLPEKFKNLKVWDIQDIDELDEKYHKEIRDALKIQQGDKNKRVKHLPKVVVRQHRPVEK
VEQQKTLTKAQWKEYQSYRKLFEKKTVKQLQELLTKNNASVSGAKEQLVYRCALSKVLGI
QPNCPSCGGQNLRFYFADGQYYCPGYLDDTDWVNCKNWFDLDEVERTKWVD