Identifiers and Description

Gene Model Identifier

TTHERM_00079530

Standard Name

CYC2 (CYClin 2)

Aliases

PreTt10198 | 5.m00549 | 3828.m01462 | COI5

Description

CYC2 amine-terminal domain cyclin; Cyclin; N-terminal domain containing protein; phosphorylates nucleotides in the middle of DNA strands during Meiosis I

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF00134 ) cyclin, N-terminal domain
  • ( PF07780 ) Spb1 C-terminal domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_06992.1 8.00224171858215e-126
Description: hypothetical protein (451 aa)
Oxytricha Contig3932.0.g1 8.997498379799854e-17
Description: Cyclin, N-terminal domain
SGD YLR210W 0.0000020007268868677913
Description: CLB4 B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:27008457: Xu Q, Wang R, Ghanam AR, Yan G, Miao W, Song X (2016) The key role of CYC2 during meiosis in Tetrahymena thermophila. Protein & cell 7(4):236-49
  2. Ref:27192402: Yan GX, Dang H, Tian M, Zhang J, Shodhan A, Ning YZ, Xiong J, Miao W (2016) Cyc17, a meiosis-specific cyclin, is essential for anaphase initiation and chromosome segregation in Tetrahymena thermophila. Cell cycle (Georgetown, Tex.) 15(14):1855-64
  3. Ref:26688337: Kataoka K, Mochizuki K (2015) Phosphorylation of an HP1-like Protein Regulates Heterochromatin Body Assembly for DNA Elimination. Developmental cell 35(6):775-88
  4. Ref:26205990: Hayashi A, Mochizuki K (2015) Targeted Gene Disruption by Ectopic Induction of DNA Elimination in Tetrahymena. Genetics 201(1):55-64
  5. Ref:25588944: Woehrer SL, Aronica L, Suhren JH, Busch CJ, Noto T, Mochizuki K (2015) A Tetrahymena Hsp90 co-chaperone promotes siRNA loading by ATP-dependent and ATP-independent mechanisms. The EMBO journal 34(4):559-77

Sequences 

>TTHERM_00079530(coding)
ATGTACATAAGTGGTAAATCAGTTATTTGCGAAAATTTGTTCAGCTCTAATTACTCGAAT
GTCACAAACTCTAACTTTTCTAATCCTCCTCTAGCTAAGTAAGAACCTATAAGTTAAAAT
CTAGTATAAAAGATGTAGTCCAATCCAAACAAGTAGAACTTACAATAAGGCTCAACATTT
GAAAAGCATACCTAGTAAAATTATGCTCTTAAGAGTTGCTCAAGCTAATTTGGTAATAAA
TAATTGGGGATCTTAAAATAAATTGATTAGAATGTAAGTAGAGACACTTAATAATCTTCA
CTGGATCGTTTGGATACTGCAAGACATTATGACAGAGTTATTTAAAGAAATGCTGTAGTA
AATTAAAAGAGTGAATTTTATGAGCATAAGCCAAACTAAGTAGCAAATCAAATGAATGAG
GAAAGCAATCTATTATCTCAACTAGCTTCTCATTGCTTTGCTGCACTAAAAAACTAAAAG
AAGCGAGAAAAAAAATAGAAACAAGATCTTATTAATTACAATAGATTTAATATTCACAAG
AGAGAATTTAATGCTAAAGCATCTAGAGAAAGCTCAAAAGAAAACTTCAAAGGGGCACCT
TCAAATCATGTAAGAAGCAATCTAAGTAGGAAGCAAAGAAGTGAAAGTAGCAACTCGTAA
AAAAATCAATCTTTGGGAAGGAGCAATAAAAAAATAACAGTTGGAATCTTGATGCAATAA
AATGGTAGCCTGTAGAAGAATGGTAATGATTAAAATAGCATGAATAAGATGTAATAGCAA
GAAAACATACACACAAAGTAAATAAGAAATACTTTAAAAGAAATTACAAACATAAAAGTG
AGACACACCAAAAATTCCAGTTAAGACATTCGTAACAACTAGCATATCTAATTTAAAAAA
GTGATGTCCTAATAAGAGACACAAAAAATATCTTCACCATAAAAAGAAGAAAACTTAATC
TCGTAAGAAAGGCTCGAGAATCCCTTGATCAAAGAGCCTTTTATTGCTCTTCAAACTATT
TCTCCAAGAGTTTTCACTAATGAATACTTTTGTTCTCTTGTAAAGCAACAATTGAATCTA
ACAAAACCTCTTGCCAGGCACTAAATAACTGATCCTATACGCTAAAAAATGATAGATTGG
ATGATTGAAGTAGTTGTGTTTGTTTTTACAAAACCTAACATCTCAGCATTTTTTAAAACA
ATAAACTTGATGGATCTATTTTTAAAAAAATCCTAAAAAAAATTTTAAGACAGCGATATT
CACTTAATAGGTGTTTGTTGTTTGATAATTAGCAATCATTTTGAATAAAGAGTTGAAGTT
GGTTTAAATCACTTCTGTCGTGAAATTGCTCATCAAGCTTTCGAAAAGAAAGATATCATA
AATATGAAAATGCATATTCTGTAAACAATAGACTATGATCTAAATTTTTCTACAGTTGCT
GACTTTAACAATTAATATATCGCATTTCTCAAGAAATATTAGAAATTAGGGAACTAATTC
TTGCAATAGTTGACTGAATTATCCTACTATTACATATTGTAATCTCACTATTTTTAAGAG
TAGCTGAGCTATCAACCTAGGATTATATCCCTTGCTTCTATTTTTGTAGCTTTAGAGTTT
TTAATTAATAATAGTAAAGACACTATCCAGGTCATAGATACATAGCTTTCTTCAATTTAA
AAAGCTTTACTTGGAGAATTTAGCTATGAAATGGATCCTTTAATGACAAGTCTTGCATTT
TGCATCAAAAATGTCAAAATGATACATCAAAACTTTGAATAAATCAATCCTAAACTTTTT
AACTATAGAGATAAATTCTAAAAGTTTATCTTGAATTGA


>TTHERM_00079530(gene)
ATGTACATAAGTGGTAAATCAGTTATTTGCGAAAATTTGTTCAGCTCTAATTACTCGAAT
GTCACAAACTCTAACTTTTCTAATCCTCCTCTAGCTAAGTAAGAACCTATAAGTTAAAAT
CTAGTATAAAAGATGTAGTCCAATCCAAACAAGTAGAACTTACAATAAGGCTCAACATTT
GAAAAGCATACCTAGTAAAATTATGCTCTTAAGAGTTGCTCAAGCTAATTTGGTAATAAA
TAATTGGGGATCTTAAAATAAATTGATTAGAATGTAAGTAGAGACACTTAATAATCTTCA
CTGGATCGTTTGGATACTGCAAGACATTATGACAGAGTTATTTAAAGAAATGCTGTAGTA
AATTAAAAGAGTGAATTTTATGAGCATAAGCCAAACTAAGTAGCAAATCAAATGAATGAG
GAAAGCAATCTATTATCTCAACTAGCTTCTCATTGCTTTGCTGCACTAAAAAACTAAAAG
AAGCGAGAAAAAAAATAGAAACAAGATCTTATTAATTACAATAGATTTAATATTCACAAG
AGAGAATTTAATGCTAAAGCATCTAGAGAAAGCTCAAAAGAAAACTTCAAAGGGGCACCT
TCAAATCATGTAAGAAGCAATCTAAGTAGGAAGCAAAGAAGTGAAAGTAGCAACTCGTAA
AAAAATCAATCTTTGGGAAGGAGCAATAAAAAAATAACAGTTGGAATCTTGATGCAATAA
AATGGTAGCCTGTAGAAGAATGGTAATGATTAAAATAGCATGAATAAGATGTAATAGCAA
GAAAACATACACACAAAGTAAATAAGAAATACTTTAAAAGAAATTACAAACATAAAAGTG
AGACACACCAAAAATTCCAGTTAAGACATTCGTAACAACTAGCATATCTAATTTAAAAAA
GTGATGTCCTAATAAGAGACACAAAAAATATCTTCACCATAAAAAGAAGAAAACTTAATC
TCGTAAGAAAGGCTCGAGAATCCCTTGATCAAAGAGCCTTTTATTGCTCTTCAAACTATT
TCTCCAAGAGTTTTCACTAATGAATACTTTTGTTCTCTTGTAAAGCAACAAGTAAATTTT
ATTTAAATTCTATTTTGGATTTCAGTAATCTAAATATATATTTTTTAAGCATTTAATTTT
TAAATTTAATATTAAAACAATTTTTTAATTGCTGATTTTTATAAATTCATTATTTATTTG
CTTTTTGTTAAAGAAAATTTATTGGTTAATATAAAAATTATTTTTTATTAAAAGTTGAAT
CTAACAAAACCTCTTGCCAGGCACTAAATAACTGATCCTATACGCTAAAAAATGATAGAT
TGGATGATTGAAGTAGTTGTGTTTGTTTTTACAAAACCTAACATCTCAGCATTTTTTAAA
ACAATAAACTTGATGGATCTATTTTTAAAAAAATCCTAAAAAAAGTAATAAAATATTTAT
TATTTGATCTTTTTTTACATCTTATTGTAAATAAAACAGATTTTAAGACAGCGATATTCA
CTTAATAGGTGTTTGTTGTTTGATAATTAGCAATCATTTTGAATAAAGAGTTGAAGTTGG
TTTAAATCACTTCTGTCGTGAAATTGCTCATCAAGCTTTCGAAAAGAAAGATATCATAAA
TATGAAAATGCATATTCTGTAAACAATAGACTATGATCTAAATTTTTCTACAGTTGCTGA
CTTTAACAATTAATATATCGCATTTCTCAAGAAATATTAGAAATTAGGGAACTAATTCTT
GCAATAGTTGACTGAATTATCCTACTATTACATATTGTAATCTCACTATTTTTAAGAGTA
GCTGAGCTATCAACCTAGGATTATATCCCTTGCTTCTATTTTTGTAGCTTTAGAGTTTTT
AATTAATAATAGTAAAGACACTATCCAGGTCATAGATACATAGCTTTCTTCAATTGTAAA
TTATTATTAAATATTTTTAATTTAATATTTAACAAAATTAATAGTAAAAAGCTTTACTTG
GAGAATTTAGCTATGAAATGGATCCTTTAATGACAAGTCTTGCATTTTGCATCAAAAATG
TCAAAATGATACATCAAAACTTTGAATAAATCAATCCTAAACTTTTTAACTATAGAGATA
AATTCTAAAAGTTTATCTTGAATTGA


>TTHERM_00079530(protein)
MYISGKSVICENLFSSNYSNVTNSNFSNPPLAKQEPISQNLVQKMQSNPNKQNLQQGSTF
EKHTQQNYALKSCSSQFGNKQLGILKQIDQNVSRDTQQSSLDRLDTARHYDRVIQRNAVV
NQKSEFYEHKPNQVANQMNEESNLLSQLASHCFAALKNQKKREKKQKQDLINYNRFNIHK
REFNAKASRESSKENFKGAPSNHVRSNLSRKQRSESSNSQKNQSLGRSNKKITVGILMQQ
NGSLQKNGNDQNSMNKMQQQENIHTKQIRNTLKEITNIKVRHTKNSSQDIRNNQHIQFKK
VMSQQETQKISSPQKEENLISQERLENPLIKEPFIALQTISPRVFTNEYFCSLVKQQLNL
TKPLARHQITDPIRQKMIDWMIEVVVFVFTKPNISAFFKTINLMDLFLKKSQKKFQDSDI
HLIGVCCLIISNHFEQRVEVGLNHFCREIAHQAFEKKDIINMKMHILQTIDYDLNFSTVA
DFNNQYIAFLKKYQKLGNQFLQQLTELSYYYILQSHYFQEQLSYQPRIISLASIFVALEF
LINNSKDTIQVIDTQLSSIQKALLGEFSYEMDPLMTSLAFCIKNVKMIHQNFEQINPKLF
NYRDKFQKFILN