Identifiers and Description

Gene Model Identifier

TTHERM_00085220

Standard Name

MRK1 (MAP-related kinase )

Aliases

MRK | PreTt16370 | 6.m00444 | 3836.m02037

Description

MRK1 MEK kinase; MAP-related kinase; recombinant MRK autophosphorylates- and phosphorylates myelin basic protein (MBP); transcription increases with temperature downshift from 35 to 15 degrees C- or with osmotic shock

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Molecular Function

• glutathionylspermidine synthase activity (IEA) | GO:0008885
• methylammonium channel activity (IDA) | GO:0015264 | Ref:10187773

Biological Process

• adaxial/abaxial axis specification (IEA) | GO:0009943
• courtship behavior (IEA) | GO:0007619
• learning (ISS) | GO:0007612 | Ref:10187773
• peptidyl-cysteine acetylation (IEP) | GO:0018533 | Ref:10187773
• regulation of juvenile hormone metabolic process (IEA) | GO:0007556

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase
• ( PF08194 ) DIM protein

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_02429.1	7.996875492733741e-171
	Description: protein kinase domain-containing protein (625 aa)
Oxytricha	Contig10155.0.g64	2.0007864815129413e-165
	Description: Protein kinase domain
DictyBase	DDB_G0286353	2.9998512931988133e-83
	Description: erkA on chromosome: 4 position 4355028 to 4356796
Stentor Coeruleus	SteCoe_12365	8.854771883513433e-70
	Description: None
WormBase	WBGene00003401	4.001968334034435e-68
	Description: locus:mpk-1 Mitogen-activated protein kinase mpk-1 status:Confirmed UniProt:P39745 protein_id:CAA87057.1
SGD	YHR030C	5.999140071902665e-66
	Description: SLT2 Serine/threonine MAP kinase; involved in regulating maintenance of cell wall integrity, progression through the cell cycle, and nuclear mRNA retention in heat shock; required for mitophagy and pexophagy; affects recruitment of mitochondria to the phagophore assembly site (PAS); regulated by the PKC1-mediated signaling pathway

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,
2. Ref:10735176: Nakashima S, Nozawa Y (1999) Stress-responsive gene expression in Tetrahymena. Acta biologica Hungarica 50(4):413-24
3. Ref:10187773: Nakashima S, Wang S, Hisamoto N, Sakai H, Andoh M, Matsumoto K, Nozawa Y (1999) Molecular cloning and expression of a stress-responsive mitogen-activated protein kinase-related kinase from Tetrahymena cells. The Journal of biological chemistry 274(15):9976-83

Sequences

>TTHERM_00085220(coding)
ATGGACAAAAAGTTATCTTCCAAGAATTTTTCCGACTGGGAGGTTGGTGATAGATATGAT
CTTATTAAGGTTGTAGGTAGTGGTTCTTATGGTTCTGTAGCTGAAGCTACTGACAAGAAA
TCAGGCAAGAAAGTTGCCATTAAGAGATTGAATGGTATCTTCGAAGACAATGTTGACTGC
AAACGTATTCTTAGAGAAATTCACTTGTTACGTATTTTAAATCACCCTAACCTTATTAGA
ATCAATGAAATTATTGAACCTAAGGACTTATAGAACTTCGACACTCTTTATGTCGTTACT
GAATATTGCTAATCCGACCTTAAAAAGCTCTTCAAGTCACCTATTCACTTGTGCATGATC
CAAGTTTAAACATTAACCTACAACATTCTCACTGGTATTAAATATCTCCACTCTGCTGAA
GTACTTCATAGAGATCTCAAGCCTGCTAACGTCCTTATCAATGAAGATTGCTCTGTCAAG
ATTTGTGACTTTGGTCTCGCCAGATCTGTAGAAGGTATTGAAGGTGCACATATTTATGAT
GATAGAAATAGCAACAGCCCTCAAAAGTAATAAACCAGTAGCCAAAGCCCTGAAAAGCCT
GCAGCTACCAGCAGTGGAAGACCTAAACTTTCTAAAGAAAAGGGAATTAACTCTAAAACC
ACTAAGAGAGAATTGACTGGCCACGTAGTTACTCGTTGGTACAGAGCTCCCGAATTGATT
CTTTTGGAAAAAGATTACACTGCTGCCATTGATATCTGGAGTATTGGTTGTATCTTCGCT
GAATTGATGAATATGATCAAGGAAAACTCCCCCACCTTCTTAGATAGATCTCCTCTTTTC
CCTGGTAGCAGCTGCTTCCCCCTCTCACCTGATAGAAACAACACAGTTAAGTAGGGTGGA
TTCCCCCACAGCCACAGTGATTAATTGAATGTCATCTTCTCAGTCTTGGGTACCCCTAAT
GAAGAAGATATGGACTTCGTCACTGATGCTAAGGCTATCGAATATTTAAAGAGCTTCAAG
CAAAAGAAGAGAGTCGACTTCAAGGATTTATTCCCAGCTGCCACCCCTGAATGTATTGAT
TTCTTGAACAAAACCCTTGTCTTCAACCCTCGTAAAAGAATTACTATTGATGCTGCCCTC
AACCATCCTCTCTTTACCCCTGTCAGAGATATCAAGAAAGAAGTATTTGCTGATGGCTCC
GTTGTTCTTCCCTTTGAAAAAGAAGGAGACATGGCTATACCTAGACTCCGTGAACTCTTC
ATCGAAGAAATCAAGCGTTATCACACTAAGTGA

>TTHERM_00085220(gene)
ATGGACAAAAAGTTATCTTCCAAGAATTTTTCCGACTGGGAGGTTGGTGATAGATATGAT
CTTATTAAGGTTGTAGGTAGTGGTTCTTATGGTTCTGTAGCTGAAGCTACTGACAAGAAA
TCAGGCAAGAAAGTTGCCATTAAGAGATTGAATGGTATCTTCGAAGACAATGTTGACTGC
AAACGTATTCTTAGAGAAATTCACTTGTTACGTATTTTAAATCACCCTAACCTTATTAGA
ATCAATGAAATTATTGAACCTAAGGACTTATAGAACTTCGACACTCTTTATGTCGTTACT
GAATATTGCTAATCCGACCTTAAAAAGCTCTTCAAGTCACCTATTCACTTGTGCATGATC
CAAGTTTAAACATTAACCTACAACATTCTCACTGGTATTAAATATCTCCACTCTGCTGAA
GTACTTCATAGAGATCTCAAGCCTGCTAACGTCCTTATCAATGAAGATTGCTCTGTCAAG
ATTTGTGACTTTGGTCTCGCCAGATCTGTAGAAGGTAATTAAAATCTCAGATTTTCATTT
TTCACTTTCTCACTTTTGATTGGCTTTATCATTTATTTAACACTTTTAAGGATGAAAATG
ATCCTCCTTCTTCTATTTCTCAAATACCATAAAGTCAAATAGTAATAATAAATGTTAAAT
AACAATATCATGTTAAATTGCTATACAACTTCTACTTTTTGATTCATTTAAAACTCATTT
TTATACATTTTTCTATCAAATATAATCTAATTGGTTTTAAAAAAACCGAATTTCTAAAAC
TAATCTAAAGAAATTCTTAAACAGAATTAATATCCACAGGCAATGACTTCAAGAAGTCGT
TGTTTAAACAAACACTACTCCAAAATATTATTAAAATTAAAAAAAAATCTCCACATTGAA
GATGATCTGCAAGAGTTTATCCTAAAAACTCGAGTAATAAATAAATAAAAGAAATATAAA
TAGATCAAATTGTTAAATGAATAATCGAGTTTGTTTCTAAAAAAATAAAATAAACAATAA
AAGTCTACTTAACATAGCTCATTTCATGATGAATTTAGCTAATAAATAGATGATAACCTA
GCAATCTTAGTAAATTAGGAAAATATAATTCAAGATTAATAATAGATAGTCAAGGCGATA
GAAACAAAGAAAGAAAGAAAAAATAAAAATAGATATTTCAGCAAACAAAATAGCAAAATA
AAATTCTATGAAAAAAAAACATAAAGAAATTTAAATAATTATCAGCAAGCATCAAATTAA
TTATTGTAAAAAGCAGATAGATAGATAGATTAAAAATTCTTATGTTAATCTAAGAATAAA
TTTTAGCCAACAATAATTTTTTTAATTAAAAAATTGTCTTTTTTATTTTTATTAAATAAA
TAATTAATTAAATTAATAAAATAAAGGTATTGAAGGTGCACATATTTATGATGATAGAAA
TAGCAACAGCCCTCAAAAGTAATAAACCAGTAGCCAAAGCCCTGAAAAGCCTGCAGCTAC
CAGCAGTGGAAGACCTAAACTTTCTAAAGAAAAGGGAATTAACTCTAAAACCACTAAGAG
AGAATTGACTGGCCACGTAGTTACTCGTTGGTACAGAGCTCCCGAATTGATTCTTTTGGA
AAAAGATTACACTGCTGCCATTGATATCTGGAGTATTGGTTGTATCTTCGCTGAATTGAT
GAATATGATCAAGGAAAACTCCCCCACCTTCTTAGATAGATCTCCTCTTTTCCCTGGTAG
CAGCTGCTTCCCCCTCTCACCTGATAGAAACAACACAGTTAAGTAGGGTGGATTCCCCCA
CAGCCACAGTGATTAATTGAATGTCATCTTCTCAGTCTTGGGTACCCCTAATGAAGAAGA
TATGGACTTCGTCACTGATGCTAAGGCTATCGAATATTTAAAGAGCTTCAAGCAAAAGAA
GAGAGTCGACTTCAAGGATTTATTCCCAGCTGCCACCCCTGAATGTATTGATTTCTTGAA
CAAAACCCTTGTCTTCAACCCTCGTAAAAGAATTACTATTGATGCTGCCCTCAACCATCC
TCTCTTTACCCCTGTCAGAGATATCAAGAAAGAAGTATTTGCTGATGGCTCCGTTGTTCT
TCCCTTTGAAAAAGAAGGAGACATGGCTATACCTAGACTCCGTGAACTCTTCATCGAAGA
AATCAAGCGTTATCACACTAAGTGA

>TTHERM_00085220(protein)
MDKKLSSKNFSDWEVGDRYDLIKVVGSGSYGSVAEATDKKSGKKVAIKRLNGIFEDNVDC
KRILREIHLLRILNHPNLIRINEIIEPKDLQNFDTLYVVTEYCQSDLKKLFKSPIHLCMI
QVQTLTYNILTGIKYLHSAEVLHRDLKPANVLINEDCSVKICDFGLARSVEGIEGAHIYD
DRNSNSPQKQQTSSQSPEKPAATSSGRPKLSKEKGINSKTTKRELTGHVVTRWYRAPELI
LLEKDYTAAIDIWSIGCIFAELMNMIKENSPTFLDRSPLFPGSSCFPLSPDRNNTVKQGG
FPHSHSDQLNVIFSVLGTPNEEDMDFVTDAKAIEYLKSFKQKKRVDFKDLFPAATPECID
FLNKTLVFNPRKRITIDAALNHPLFTPVRDIKKEVFADGSVVLPFEKEGDMAIPRLRELF
IEEIKRYHTK