Identifiers and Description

Gene Model Identifier

TTHERM_00095530

Standard Name

DRH10 (DExD/H box RNA Helicase 10)

Aliases

PreTt22852 | 7.m00301

Description

DRH10 DEAD/DEAH-box helicase; DEAD/DEAH box helicase family protein; sequence similarity to a protein kinase family unique to Tetrahymena thermophila; associated with ribosome biogenesis

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• nucleolus (IDA) | GO:0005730

Molecular Function

• ATP binding (IEA) | GO:0005524
• ATP-dependent helicase activity (IEA) | GO:0008026
• helicase activity (IEA) | GO:0004386
• nucleic acid binding (IEA) | GO:0003676

Biological Process

• ribosome biogenesis (IEP) | GO:0042254

Domains

• ( PF00270 ) DEAD/DEAH box helicase
• ( PF00271 ) Helicase conserved C-terminal domain
• ( PF04851 ) type III restriction enzyme, res
• ( TIGR00614 ) ATP-dependent DNA helicase, RecQ family
• ( TIGR01587 ) CRISPR-associated helicase Cas3

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
WormBase	WBGene00012059	9.997093137033517e-262
	Description: Putative ATP-dependent RNA helicase T26G10.1 status:Confirmed UniProt:P34580 protein_id:CAA82362.1
Tetrahymena borealis	EI9_00258.1	9.997093137033517e-262
	Description: DEAD/DEAH box helicase (522 aa)
DictyBase	DDB_G0280147	9.997093137033517e-262
	Description: ddx47 on chromosome: 3 position 3015956 to 3017596
Oxytricha	Contig22569.0.g63	9.997093137033517e-262
	Description: DEAD/DEAH box helicase
SGD	YHR065C	2.0000633521090825e-149
	Description: RRP3 Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; homologous to eIF-4a, which is a DEAD box RNA-dependent ATPase with helicase activity
Stentor Coeruleus	SteCoe_16450	5.440559879258653e-75
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00095530(coding)
ATGTCAACTAAACAAATTCAGAAAAAAGCCAACACAGCAGTTCAAAGCAAGAAATCTTAA
AAGATAGAAGAAAAGAAAAAAGATTAGCTTAAGAAACTTGCTGAAGAAGAAGATGAAGTA
GAATAAAGTAGTGACGAAGAACAAGAAGAATCCTAAGAATTAAATGATGATTCAGCTGAA
AAATAATAGGCTAAACAAGAAAATAAGAATGGAGATTAAGAAAATAAAAGCGGAAGCGAA
TACTTAAAAGAAATTTAAATTGATGAAACTGAAGAAAAAGAAGATGTGACCTTTTAAAGC
TTAGGAGTTTGTGAAGAATTAGTAGAAGCTTGCAATAGATTAAAATATGTGAAACCCACT
GCAATTTAAAGAGAATCTTTAGTTTATACATTAAAGCAAAGAGATATTATTGCTTTAGCA
GAAACAGGTTCTGGTAAAACTTTAGCTTTTGCTTTACCTGTTATTCAAAATTTGTTAGAT
GCTCCTCAACCTTTCTACGCTTTAGTTCTTTCTCCTACAAGAGAATTGTGTATGTAAATT
GCTGAGCACTTTGAAGCTTTGGGTGTTGGTATAAGCTTAAAGACAACAGTTATTGTTGGT
GGTCTTGATCCTATGGCTTAGGCTATTGCTCTCTCTAAAAAGCCCCACATCATCATTGGT
ACTCCAGGTAGAATACTTTATCACATGCAAAACACCAAAGGATTTAATTTCAAGGCACTC
AAGTTCTTAGTTTTGGATGAAGCTGATAAGTTATTGAATATGGATTTCGAAAAGGATATC
AACCAAATTTTGGATATCATTCCTAAAAAGCGTAACACATTCTTATTCTCTGCCACTATG
ACTAATAAGGTTCATAAGCTTCAGAGAGCTTCACTCAAAGATCCTGTTAAAATTGAAGTT
TCTTCAAAGTATCAAATGGTTTCAACTTTAGTTGCTTAGTATGCTTTCATACCTGCCAAG
TACAAAGACTGCTACCTTGTCTATTCCCTCAATGAATTTGCAGGAAACACCTCAATTATT
TTCGTTCAAACTTGCTTAAATGCTATCAAGTTAACTTTGATGCTTAGAAATCTTGGATTC
TCAGCTGTTACTATCCATGGTTAAATGAGTTAGGTCAAGCGTTTGGGTGCTATTAATAAA
TTTAAATCAGGAGAGAAAAAAATATTAGTTGCTACTGATGTTGCTTCTAGAGGTTTAGAT
ATTCCAAGTGTTGATTTAGTTATAAACTACGATATTCCTACAAATGCCAAGGAATACGTC
CACAGAGTAGGTAGAACTGCAAGAGCTGGTAGAGCTGGTAAAGCCATTAGCTTTGTTACT
CAATATGATGTTGAAATGTATTTAAAGATTGAAGCTTTGATTGGTAAAAAACTTGATCAA
TATAAATGTGAAGAATATTAAGTTTTAGTTTTCAACGAAAGAGTTTAAGAAGCTCAAAGA
ATCGCTGCATAAGAAATAAAAGAAATTATGGAAAAAAAGAACAATCCTCTCCATGATGTT
GATGATGAAGGTGAAAAATACAGTAAGAAAAATGCAAATAACAACAGAAAGAAAAGCTTC
AATAATTCTAAGAATATGAAAAAAATGAAAATAGATATTTGA

>TTHERM_00095530(gene)
ATGTCAACTAAACAAATTCAGAAAAAAGCCAACACAGCAGTTCAAAGCAAGAAATCTTAA
AAGATAGAAGAAAAGAAAAAAGATTAGCTTAAGAAACTTGCTGAAGAAGAAGATGAAGTA
GAATAAAGTAGTGACGAAGAACAAGAAGAATCCTAAGAATTAAATGATGATTCAGCTGAA
AAATAATAGGCTAAACAAGAAAATAAGAATGGAGATTAAGAAAATAAAAGCGGAAGCGAA
TACTTAAAAGAAATTTAAATTGATGAAACTGAAGAAAAAGAAGATGTGACCTTTTAAAGC
TTAGGAGTAAAATTTAAATTAATATTTTGAAAAAAATATCATTTTTGTACATAAAATTAA
TGTTTAGGTTTGTGAAGAATTAGTAGAAGCTTGCAATAGATTAAAATATGTGAAACCCAC
TGCAATTTAAAGAGAATCTTTAGTTTATACATTAAAGCAAAGAGATATTATTGCTTTAGC
AGAAACAGGTTCTGGTAAAACTTTAGCTTTTGCTTTACCTGTTATTCAAAATTTGTTAGA
TGCTCCTCAACCTTTCTACGCTTTAGTTCTTTCTCCTACAAGAGAATTGTGTATGTAAAT
TGCTGAGCACTTTGAAGCTTTGGGTGTTGGTATAAGCTTAAAGACAACAGTTATTGTTGG
TGGTCTTGATCCTATGGCTTAGGCTATTGCTCTCTCTAAAAAGCCCCACATCAGTAATTT
CTTTTAAATTTTAAAATATGAAAATATAAAATTAAATTTTGCTATTTTGAAGATTTAAGT
GTACTTAATTAGTTTATACACTTACTTGAACTTGTAGCAATTATTATTCATACTATTTTT
GCAAAACCAGTGAAATGAATATAAAGAAATTAATTGCTTTGTTTTAATAAATAGTCATTG
GTACTCCAGGTAGAATACTTTATCACATGCAAAACACCAAAGGATTTAATTTCAAGGCAC
TCAAGTTCTTAGTTTTGGATGAAGCTGATAAGTTATTGAATATGGATTTCGAAAAGGATA
TCAACCAAATTTTGGATATCATTCCTAAAAAGCGTAACACATTCTTATTCTCTGCCACTA
TGACTAATAAGGTTCATAAGCTTCAGAGAGCTTCACTCAAAGATCCTGTTAAAATTGAAG
TTTCTTCAAAGTATCAAATGGTTTCAACTTTAGTTGCTTAGTATGCTTTCATACCTGCCA
AGTACAAAGACTGCTACCTTGTCTATTCCCTCAATGAATTTGCAGGAAACACCTCAATTA
TTTTCGTTCAAACTTGCTTAAATGCTATCAAGTAACAAATAAATAAAAACAATTTTTGAA
TTTATTTTTAGAATTAAATTTACTAACAAATTAGGTTAACTTTGATGCTTAGAAATCTTG
GATTCTCAGCTGTTACTATCCATGGTTAAATGAGTTAGGTCAAGCGTTTGGGTGCTATTA
ATAAATTTAAATCAGGAGAGAAAAAAATATTAGTTGCTACTGATGTTGCTTCTAGGTAAT
TAAATTAATTGATAATTTTATATGTCTTTCTGTATAAAGATTTTTGATTAAATTTTATAT
TAAATAATATATAGAGGTTTAGATATTCCAAGTGTTGATTTAGTTATAAACTACGATATT
CCTACAAATGCCAAGGAATACGTCCACAGAGTAGGTAGAACTGCAAGAGCTGGTAGAGCT
GGTAAAGCCATTAGCTTTGTTACTCAATATGATGTTGAAATGTATTTAAAGATTGAAGCT
TTGATTGGTAAAAAACTTGATCAATATAAATGTGAAGAATATTAAGTTTTAGTTTTCAAC
GAAAGAGTTTAAGAAGCTCAAAGAATCGCTGCATAAGAAATAAAAGAAATTATGGAAAAA
AAGAACAATCCTCTCCATGATGTTGATGATGAAGGTGAAAAATACAGTAAGAAAAATGCA
AATAACAACAGAAAGAAAAGCTTCAATAATTCTAAGAATATGAAAAAAATGAAAATAGAT
ATTTGA

>TTHERM_00095530(protein)
MSTKQIQKKANTAVQSKKSQKIEEKKKDQLKKLAEEEDEVEQSSDEEQEESQELNDDSAE
KQQAKQENKNGDQENKSGSEYLKEIQIDETEEKEDVTFQSLGVCEELVEACNRLKYVKPT
AIQRESLVYTLKQRDIIALAETGSGKTLAFALPVIQNLLDAPQPFYALVLSPTRELCMQI
AEHFEALGVGISLKTTVIVGGLDPMAQAIALSKKPHIIIGTPGRILYHMQNTKGFNFKAL
KFLVLDEADKLLNMDFEKDINQILDIIPKKRNTFLFSATMTNKVHKLQRASLKDPVKIEV
SSKYQMVSTLVAQYAFIPAKYKDCYLVYSLNEFAGNTSIIFVQTCLNAIKLTLMLRNLGF
SAVTIHGQMSQVKRLGAINKFKSGEKKILVATDVASRGLDIPSVDLVINYDIPTNAKEYV
HRVGRTARAGRAGKAISFVTQYDVEMYLKIEALIGKKLDQYKCEEYQVLVFNERVQEAQR
IAAQEIKEIMEKKNNPLHDVDDEGEKYSKKNANNNRKKSFNNSKNMKKMKIDI