Identifiers and Description

Gene Model Identifier

TTHERM_00112430

Standard Name

MYO1 (MYOsin)

Aliases

PreTt27057 | 8.m00317 | 3812.m02353

Description

MYO1 unconventional myosin heavy chain; Myosin heavy chain; molecular motor involved in phagocytosis and macronuclear elongation; has putative ATP-binding and phosphorylation sites; member of proposed Class XX, distinct from previously defined myosin classes, putative; FERM central domain

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• chloroplast ribosome (IEA) | GO:0043253
• EGFR-Grb2-Sos complex (IEA) | GO:0070620
• heterochromatin domain (IEA) | GO:1990343
• M band (IEA) | GO:0031430
• myosin complex (ISS) | GO:0016459
• obsolete integral component of mitochondrial membrane (IEA) | GO:0032592
• obsolete transforming growth factor beta1-type II receptor complex (IEA) | GO:0070020
• protein storage vacuole (IEA) | GO:0000326
• synaptobrevin 2-SNAP-25-syntaxin-3 complex (IEA) | GO:0070046

Molecular Function

• 11-deoxycorticosterone binding (IEA) | GO:1903878
• 17alpha-hydroxyprogesterone binding (IEA) | GO:1903880
• 2-octaprenyl-6-methoxyphenol hydroxylase activity (IEA) | GO:0008681
• alpha-humulene synthase activity (IEA) | GO:0080017
• arsenate reductase (glutaredoxin) activity (IEA) | GO:0008794
• ATP binding (ISS) | GO:0005524
• cAMP-dependent protein kinase regulator activity (IEA) | GO:0008603
• corticotrophin-releasing factor receptor activity (IEA) | GO:0015056
• cytoskeletal motor activity (ISS) | GO:0003774
• G protein-coupled serotonin receptor binding (IEA) | GO:0031821
• glucuronate-2-sulfatase activity (IEA) | GO:0015024
• GTP:coenzyme F420 guanyltransferase activity (IEA) | GO:0052754
• Janus kinase activity (IEA) | GO:0004718
• kappa-type opioid receptor binding (IEA) | GO:0031851
• lysine:proton symporter activity (IEA) | GO:0015493
• methane monooxygenase [NAD(P)H] activity (IEA) | GO:0015049
• microtubule severing ATPase activity (IEA) | GO:0008568
• minus-end directed microfilament motor activity (IEA) | GO:0060001
• mitochondrial heavy strand promoter sense binding (IEA) | GO:0070364
• obsolete cation:cation antiporter activity (IEA) | GO:0015491
• obsolete GPI-anchored membrane-bound receptor (IEA) | GO:0015025
• obsolete phosphatidylinositol 3-kinase, class I, catalyst activity (IEA) | GO:0015072
• obsolete protein tagging activity (IEA) | GO:0008638
• obsolete RNA polymerase I transcription regulator recruiting activity (IEA) | GO:0001186
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• obsolete tubulin GTPase activity (IEA) | GO:0008550
• obsolete type II protein secretor activity (IEA) | GO:0015447
• phosphatidylinositol-3-phosphate binding (IEA) | GO:0032266
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• protein tyrosine kinase activity (IEA) | GO:0004713
• Pup ligase activity (IEA) | GO:0061664
• RNA 2',3'-cyclic 3'-phosphodiesterase activity (IEA) | GO:0008664
• silver ion transmembrane transporter activity (IEA) | GO:0015080
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• telomerase RNA binding (IEA) | GO:0070034
• type 4 neuropeptide Y receptor binding (IEA) | GO:0031844
• UFM1 ligase activity (IEA) | GO:0061666

Biological Process

• (R)-mevalonic acid biosynthetic process (IEA) | GO:1901737
• 3-keto-sphinganine metabolic process (IEA) | GO:0006666
• 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process (IEA) | GO:1901949
• activation of MAPKKK activity involved in osmosensory signaling pathway (IEA) | GO:0000167
• alkaloid biosynthetic process (IEA) | GO:0009821
• amitosis (IMP) | GO:0051337
• carotenoid metabolic process (IEA) | GO:0016116
• cellular response to dimethyl sulfoxide (IEA) | GO:1904620
• cellular response to dopamine (IEA) | GO:1903351
• cellular response to hydroxyurea (IEA) | GO:0072711
• copper ion homeostasis (IEA) | GO:0055070
• detection of stimulus involved in sensory perception of pain (IEA) | GO:0062149
• embryonic process involved in female pregnancy (IEA) | GO:0060136
• establishment of bipolar cell polarity (IEA) | GO:0061171
• evoked neurotransmitter secretion (IEA) | GO:0061670
• fat cell proliferation (IEA) | GO:0070341
• fatty acid transmembrane transport (IEA) | GO:1902001
• fibroblast growth factor receptor signaling pathway (IEA) | GO:0008543
• flower phyllotactic patterning (IEA) | GO:0060773
• gibberellic acid mediated signaling pathway (IEA) | GO:0009740
• glycolytic process from glycerol (IEA) | GO:0061613
• GMP salvage (IEA) | GO:0032263
• hair cycle process (IEA) | GO:0022405
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• high density lipoprotein particle mediated signaling (IEA) | GO:0055097
• high-affinity hexose transport (IEA) | GO:0008646
• IMP salvage (IEA) | GO:0032264
• induction of apoptosis by extracellular signals (IEA) | GO:0008624
• interleukin-19 production (IEA) | GO:0032622
• interleukin-2 production (IEA) | GO:0032623
• iodide transmembrane transport (IEA) | GO:1904200
• leaf phyllotactic patterning (IEA) | GO:0060772
• low-density lipoprotein particle mediated signaling (IEA) | GO:0055096
• lung growth (IEA) | GO:0060437
• Malpighian tubule tip cell differentiation (IEA) | GO:0061382
• mannosyl-inositol phosphorylceramide metabolic process (IEA) | GO:0006675
• mast cell differentiation (IEA) | GO:0060374
• maternal process involved in parturition (IEA) | GO:0060137
• mesonephric glomerular mesangial cell fate commitment (IEA) | GO:0061264
• mesonephric interstitial fibroblast differentiation (IEA) | GO:0061266
• mitochondrial membrane organization (IEA) | GO:0007006
• mitotic cytokinetic cell separation (IEA) | GO:1902409
• mitotic nuclear division (IEA) | GO:0007067
• modulation by organism of innate immune response in other organism involved in symbiotic interaction (IEA) | GO:0052306
• negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902642
• negative regulation of axon guidance (IEA) | GO:1902668
• negative regulation of cellular glucuronidation (IEA) | GO:2001030
• negative regulation of chemokine-mediated signaling pathway (IEA) | GO:0070100
• negative regulation of filamentous growth (IEA) | GO:0060258
• negative regulation of interleukin-1 production (IEA) | GO:0032692
• negative regulation of interleukin-17-mediated signaling pathway (IEA) | GO:1903882
• negative regulation of interleukin-4-mediated signaling pathway (IEA) | GO:1902215
• negative regulation of L-glutamine biosynthetic process (IEA) | GO:0062133
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• negative regulation of phospholipid translocation (IEA) | GO:0061093
• negative regulation of postsynaptic membrane organization (IEA) | GO:1901627
• neosartoricin metabolic process (IEA) | GO:1902048
• neutral lipid metabolic process (IEA) | GO:0006638
• nitrate transmembrane transport (IEA) | GO:0015706
• obsolete activation of MAPK activity (IEA) | GO:0000187
• obsolete di-, tri-valent inorganic cation homeostasis (IEA) | GO:0055066
• obsolete energy taxis in environment of other organism involved in symbiotic interaction (IEA) | GO:0052215
• obsolete histone succinylation (IEA) | GO:0106077
• obsolete loss of asymmetric budding (IEA) | GO:0007122
• obsolete metal ion homeostasis (IEA) | GO:0055065
• obsolete modulation of catalytic activity in other organism involved in symbiotic interaction (IEA) | GO:0052203
• obsolete modulation of molecular function in other organism involved in symbiotic interaction (IEA) | GO:0052205
• obsolete modulation of peptidase activity in other organism involved in symbiotic interaction (IEA) | GO:0052198
• obsolete mRNA endonucleolytic cleavage involved in unfolded protein response (IEA) | GO:0070055
• obsolete multi-organism cellular localization (IEA) | GO:1902581
• obsolete negative regulation by host of symbiont defense response (IEA) | GO:0052196
• obsolete negative regulation of histone H3-K18 acetylation (IEA) | GO:1902030
• obsolete negative regulation of L-leucine import (IEA) | GO:0060358
• obsolete positive regulation by host of symbiont defense response (IEA) | GO:0052197
• obsolete positive regulation of nucleic acid-templated transcription (IEA) | GO:1903508
• obsolete regulation of apurinic/apyrimidinic endodeoxyribonuclease activity (IEA) | GO:0052721
• obsolete regulation of nucleic acid-templated transcription (IEA) | GO:1903506
• obsolete response to lipoic acid (IEA) | GO:1990479
• obsolete response to long exposure to lithium ion (IEA) | GO:0043460
• obsolete telomere binding (IEA) | GO:0007003
• ommochrome biosynthetic process (IEA) | GO:0006727
• P granule disassembly (IEA) | GO:1903864
• peptidyl-lysine propionylation (IEA) | GO:0061921
• peripheral tolerance induction to nonself antigen (IEA) | GO:0002464
• phagocytosis (IEA) | GO:0006909
• phagocytosis (IMP) | GO:0006909
• photosynthesis, light harvesting in photosystem I (IEA) | GO:0009768
• photosynthetic NADP+ reduction (IEA) | GO:0009780
• phyllotactic patterning (IEA) | GO:0060771
• plant-type cell wall modification (IEA) | GO:0009827
• polyamine acetylation (IEA) | GO:0032917
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of actin binding (IEA) | GO:1904618
• positive regulation of ATF6-mediated unfolded protein response (IEA) | GO:1903893
• positive regulation of cell cycle (IMP) | GO:0045787
• positive regulation of cell-cell adhesion (IEA) | GO:0022409
• positive regulation of double-strand break repair via nonhomologous end joining (IEA) | GO:2001034
• positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization (IEA) | GO:0061646
• positive regulation of interleukin-4-mediated signaling pathway (IEA) | GO:1902216
• positive regulation of protein processing (IEA) | GO:0010954
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• prostate induction (IEA) | GO:0060514
• protein K27-linked deubiquitination (IEA) | GO:1990167
• protein localization to nucleoplasm (IEA) | GO:1990173
• protein localization to old growing cell tip (IEA) | GO:1903858
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902646
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of atrial cardiac muscle cell membrane repolarization (IEA) | GO:0060372
• regulation of cellular respiration (IEA) | GO:0043457
• regulation of chitin metabolic process (IEA) | GO:0032882
• regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
• regulation of dendrite extension (IEA) | GO:1903859
• regulation of flocculation (IEA) | GO:0060256
• regulation of frizzled signaling pathway (IEA) | GO:0008590
• regulation of interleukin-27-mediated signaling pathway (IEA) | GO:0070107
• regulation of pentose-phosphate shunt (IEA) | GO:0043456
• regulation of positive chemotaxis to cAMP by DIF-1 (IEA) | GO:0061120
• regulation of protein localization to cell cortex (IEA) | GO:1904776
• regulation of protein localization to cell division site (IEA) | GO:1901900
• regulation of Wnt signaling pathway, calcium modulating pathway (IEA) | GO:0008591
• response to high density lipoprotein particle (IEA) | GO:0055099
• response to iron(II) ion (IEA) | GO:0010040
• response to low-density lipoprotein particle stimulus (IEA) | GO:0055098
• response to methamphetamine hydrochloride (IEA) | GO:1904313
• response to oxygen radical (IEA) | GO:0000305
• response to reactive oxygen species (IEA) | GO:0000302
• semaphorin-plexin signaling pathway involved in outflow tract morphogenesis (IEA) | GO:0071527
• single-organism intracellular transport (IEA) | GO:1902582
• striated muscle myosin thick filament assembly (IEA) | GO:0071688
• T cell mediated immune response to tumor cell (IEA) | GO:0002424
• trabecula morphogenesis (IEA) | GO:0061383
• vacuolar acidification (IEA) | GO:0007035

Domains

• ( PF00063 ) Myosin head (motor domain)
• ( PF00373 ) FERM central domain
• ( PF00784 ) MyTH4 domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No.	Gene Name(s)	Paragraph Text
2217	MYO10, MYO11, MYO1, MYO4, MYO9, MYO5, MYO12, MYO3, MYO13, MYO4a, MYO2	Proteins of the myosin superfamily are ATP-dependent molecular motors that travel unidirectionally along actin filaments. The myosin heavy chain proteins are comprised of three domains: a head (motor) domain responsible for ATP hydrolysis at the N-terminus, a neck (lever arm) region, and a C-terminal tail region. Thirteen predicted myosin heavy chain genes have been identified in the Tetrahymena genome and named MYO1-MYO13. A phylogenetic analysis comparing these predicted proteins with the 19 previously identified myosin classes suggests that Myo1p-Myo12p belong to a previously undescribed class of myosins. This new family, designated Class XX, does not include Myo13p, which did not branch with this class or any of the other classes in the analysis. The neck and tail regions of the Tetrahymena myosins include a variety of domains characterized in other myosin classes, with each protein containing one or more of the following domains: coiled-coil (which may support dimerization); IQ motif (binding sites for calmodulin or calmodulin-like proteins); FERM domain (Four-point-one protein, Ezrin, Radixin, Moesin homology); and MyTH4 domain (Myosin Tail Homology 4).

Associated Literature

1. Ref:17688250: Hosein RE, Gavin RH (2007) Myo1 localizes to phagosomes, some of which traffic to the nucleus in a Myo1-dependent manner in Tetrahymena thermophila. Cell motility and the cytoskeleton 64(12):926-35
2. Ref:16505385: Foth BJ, Goedecke MC, Soldati D (2006) New insights into myosin evolution and classification. Proceedings of the National Academy of Sciences of the United States of America 103(10):3681-6
3. Ref:15988740: Williams SA, Gavin RH (2005) Myosin genes in Tetrahymena. Cell motility and the cytoskeleton 61(4):237-43
4. Ref:15810016: Hosein RE, Williams SA, Gavin RH (2005) Directed motility of phagosomes in Tetrahymena thermophila requires actin and Myo1p, a novel unconventional myosin. Cell motility and the cytoskeleton 61(1):49-60
5. Ref:11128708: Williams SA, Hosein RE, Garcés JA, Gavin RH (2000) MYO1, a novel, unconventional myosin gene affects endocytosis and macronuclear elongation in Tetrahymena thermophila. The Journal of eukaryotic microbiology 47(6):561-8
6. Ref:9627986: Garcés J, Gavin RH (1998) A PCR screen identifies a novel, unconventional myosin heavy chain gene (MYO1) in Tetrahymena thermophila. The Journal of eukaryotic microbiology 45(3):252-9

Sequences

>TTHERM_00112430(coding)
ATGAATAAAAGTTATTAAGAATGGATTAATCCTAATGTAGAGTGTTGGGTTTGGCTCAAA
TATGAAAATTCTTAGCAAAATTAAAACAATTCTGAAAATGGATAATATTTCTAGTGCGTT
ATTCAATCAGTATAAAAAGAAAAGAATTTAGCAAAGATAAAAGTTACTTGTAAAGAAGAA
TAATTAGGAAATCGAATATCAGATTAAGCAATTAATGGATAATTAGATGTTTAATTTGAA
AGATTATTAGAAAAGGAAATTATGGTTGATTCTCTTCAAACTTTAGGTTATTCAGATATG
GTTCATATGAAGTATTTAAATGAGGCTGAAATAATCAATAATTTGAGAAAGCGATATTAA
AATAATATGATTTTCACATATATTGGACCAACTTTGGTAGTTATGAATCCATATAAAGAA
ATAGAAGGAGTATAAGATAATCAAGTAATAGATAAAATAAAATCTGATCTAGGCATAAAA
TTTGAAGAGGATTTCAAAATGAATAATCTGAGCACCAACTAAAATATTATAAACACACCT
CATACATATACTGTAAGCGGATTAGCCTACAAATAAATGTTTAGCAATAAGAAAAATTAA
GCAATAGTTATATCAGGCGAAAGTGGAGCAGGTAAAACAGAAAATGCTAAATTATCGATG
CAATTTTTAACAAGTTTGAGTTCAGGGTCTGATAAATAAAATGATTTACTCAATTAATTA
AAGACTCAAACAGCTAAGAATATTCTATTAGAAGAGTTTAACTAATTTGCAATAGAAGTA
AAAATACTTGCTTGTAATCCTATTCTAGAAGCTTTTGGTAATGCTAAAACAGTAAGAAAT
AATAATTCCTCTAGATTTGGTAAATACGTAAAAATCTACATAGATAAAACATCTTAAAAG
ATAAATGGAGCCTCCATTGATAGCTACTTACTCGAAAAGAGCAGAATACCTTGTCCAGGA
AAGGGAGAGAGAAATTATCACATTTTTTACCACATGCTAAAAGGAAATCAAGAACTATCT
AATTTGAGATTGAGTTAGTTCAAAAATTTATCTGATTTTGATTATCTAAAGAAAAGTGAC
TGCTTTGAGGTTGAGAACATTTAAGATGCTAAACTCTATTTGGAAGTAAAGAAGTCCTTC
AGATAAATGAATTTCTCTAACTAAGAGTAAGAAGCTATATTTTCTCTAATATCTGCGATA
CTACTGTTAGGCAATGCAAATTTAGACTCATCAAAAGCTAGCGACACTCAGGCTCCAACT
TTTTTGAACATGAGTTTACCGACACATCATAAAGAATTCAAAAATGCCTCTGAGTTACTC
TAAGTTAATCCTAAAGACCTTGAAGAGTCTTTAGTATTTAAGGTAAGGAAAGTTGGAACT
ACAGTAATTAAATCTCCATAAACTGCTGAAGAATGCTTGTCTATGAGAGACAGTCTAAGT
AAAAATCTATATGATAGTCTTTTTAACTTTTTGGTTTGGAAGTTAAATTAAAATTTGTTG
CCACCTTAAGATTTGCTAAATAAATCATTAAGCATAGGCCTTTTAGATATATTTGGTTTT
GAGAGCTTTGATATAAACTCATTTGAGCAGCTTTGCATTAATTTTACCAATGAAAAATTT
TAGTAATTGTATGTTTAATATGTTTTCAAAAGCGAAGAAGAAGATTATAAATAAGAAGGA
ATTTTGGATGTATTTTCTGATTTATAATATTAAGAGAATTAGCTCATTATTGATACAATT
GAAAAAAAACCCAATGGAATCATGGTGCTTTTAGATGAAAATTGCTCATTGGGATCAGGG
ACGGATGATTCTTTTTTAAATTAAATTACAAAAAACCACTCTAAAAATCAACTTGTCAGC
TTCCCTAAAAAAGATAAATATTCTTTCAGCCTTAGTCATACAGCAAAACAAGTTGTATAT
GATGTGCGCGGATTTAGAGATAAAAATAAAGATGAAGTGAGTACCGAAGTAGAAAAATGT
CTTTAAAGTAGTAAATGTCCAGTTATTGCGAATTTATTATCTTATTAAGGGTCTTAAACT
TAGTAGAATAAAGAAACTTAAAATCTTCAAAATTTTGGAAATAATTTAAATTTTAAAAAA
GCTGAAATTAGTAATCAAATGAACTCAAGTAAAAAGAATGTAAAGTTTCTAGGCTAAAAA
TTTAGATAATCTTTATAGGAATTAATGATAGAATTGAATAATAGCGATGTTCACTTCATA
AGATGTATAAAACCAAACGAAGAAAAGAAAAAGAATTTTTTTAAGTATGATTATGTTTAT
TAGCAAGTACAGTATTTAGGCATACTTGATTCCATTAAAATCCGCAAAGTTGGATATTCT
TACAGAATGACTTATGAAAACTTTTTCTTAGAATACCAAGAACTGGGATAGAAAACAAAA
GGATTAACATTGTAGAAGGTTTAGCAATAAAAGTTAGATTTAAAATAATTAATTACAACA
GAAATATTTGAAAAGACCAATTTATTGCAAAATAAATAACTTCCTTAGAAATGTGTAGCA
TTTGGAAAAACAAAAATATTTCTCAAAAATGAAGTTATGAAGATTTTGCATGAAAAAATT
TAAGAAATTATTTAATAAAGAAAAAAATATGCAAAGCGAATTATTGTCTCAATTTAAAAA
TATCTGTTTAGGAAATACTTCCATAAGAATTTAATGAAAATAAAAAATTAATTAATTAAA
TTGCAATCATTTGCTAGAATGGCTATTTAAAGATAAAAATTCCTAAGGAAAAAGAAATCA
ATATTAAAAATGAAGAAGCTTATTAGGCTAAGAATGTTGGGATAAGGAATCTCTGCATTT
AGGTTAAACTATATCTCATTTGTGTGGGATTTGGTTTGTTTTATGATATTTGATAAAACA
AATATTCATATTGCATTTTAGTAAATTAAATATTATCGTAACCCAAATAAAACTAAGCCT
GTTGTTCAAAATTAAACATCTACAATTTAGTAAAATAAATAGTAAAATCAACAACCTTAA
AAAAGCCAAAATTAAGTTACTTCATCATTTTAAGTAAATAATTAAATGATGCAATAAAAA
TAAAGTCTTGTAGGCCAATAAATTTAATCTATTGTAAACGAGCTTAATTTAGGTGAGATA
TAAATTAATAAAACCTAACAAGATTTAAAAGACTTTAGAAAATCAAAGATTATACCTTAA
GTTAACTTGAATCCATCACATAGTAGTAAGAGGGCCAGCAATGCTTGGAGATAAACCCTA
ATTGCAAGTAGTAGTTAAAATAAAATTAATAAAGATTTGTAGCTATCTGAATTAGGAGAG
TAGAAGCTGATAAATATGAAAGAAACAACTGACTAAAAAGAAAAAATTAAATATACTAAA
CCTCTGATATTATAATTTACAGAGTATAACCCTGCTTATTAGTATGCAGAGTTTAATATG
GAGAGTGCAATAGATTTAGAAGATGTTCCTAATAGTTTAGATTTTGAGGGTGAATTAAAT
GATTTGATAAGTGAAGAAATCATTCAATAAATAAAAAAAAATAACTTTTATTCACACCTT
TCTTTTATTCTTGCAAAAAGAACAAAATGGGGAATCACACAAACTTAAGAGAAAATAATG
AGGCACTAGCTTAAACCAATTTCAAATCCACTAACAAATATTGCTGATTTGAAGAATATA
ATCACCTATGAAGACACAAAAGATGCTGTTTAATCAATTAGGAGTATTATTCAATAAAAT
AATTTATATAATGACACATCAACATAGACTTAAAGACCAATTAATTATGAAGATGCTAGA
ACTGGAAAATTAGATAAGTAAGTATCTAAATAAATTACTAACGATTAATCACAAAAATTA
GCAACTGTCTTTTCGAAATATTCTCTGATGAACCCAAGAAAAGCTAGTGTTAGAGACACA
AACTCACTTGAACAAATTGTCCTATAATAAAGAAAACTTACAAAATTAATTTAGTATAAA
AAATTTTCTCCTTCAGAAAAAGCTATTAACATATTTAAAACTCTCTTAAAGTGCACAGGA
GAAAGAAAATCCCGATATAACAGACACAACAATATCATAAAGCTTCTTACCCTTTGTAAC
GAAGAGTCAATCGACCTAAAAGAAGAAGTTTACGTTTAATTATGCAAATAATTAAGTGCA
AATGATAAAAAGGAGTCAAGAATAAAATATTTAAAGCTGTTTGCTATTATAAGCAGCATA
CTGCCAACAACCAGTAGATTTTATTATCCTTTACTTCACTTTTTATATATGAGAAATACA
GATACTCAAATAGAATAGGATGAGAGAAAATGGTACTAATACTGTTTTCAAAGAATTTAT
AAAAGTGAGTAAATACAAAGAGGATGCATCCCAACTGATACTGAAATTGTAATGATTGAG
AATAAGAAACAAATTTTGATTAGAGTTTATCTTCTAAATGAAATCCCAATTACTGTAGGA
GTAGAAAGCTATACTAGTGTGAAGATGCTTAAGCAGGAGCTACTTTAGAAAATAGGTATA
ACCTAAAGACATGAATATTATGGCCTTATGGAAGTAAGAAACAATATTAAGAAAAAGAGA
AAAGAAACGAGATTTATAGATGAAAGTGAGAGAGTAATGGATGTGATAGCTTTTTGGGAA
AATGAGTAGTATTTATTTGGATCTCAATTAAATTCTTCTTTCATACATAGCAACTCAAAA
TAAAATGATGAAGGTATTGAGCAATTCAACCTTTAAAATTATTAGGATCTTGAAGGACTT
AAAATTTACCTTGGAATCAGAATACTTTTTTCATTTTAAGAAAACGATAAAGAAGCAATA
AGCGTTTTCTACACTTAGCTATCTTCAGAAGTACTTGAAGGAAAGTATGCACCTTTGGAG
GAAAAAGATTACTTGAATTTGGCTGCTTTATAACTGTGCATAGATTTTCCAAGAGACGTC
ATTTTAAAAGAAATATCTAAAAGATAGAGTATCAATGCAGATAGTGGGTCTCCATAAAGA
ACATAGAGTAATTTTTTGAGTGCTACTAGCTAAAGTGAAAGCGGTGCATCACAGCTTAAA
AAGCTTTCTTATTAAGATATTGAACAGATTGATGAATAAGATGAATACGAACAATTCATA
TAAAATAGAAATGAAATTTTAATTGATCCGGTTTTTTACATACCAGCTAAAATGTATTTC
TAAAAAGATATTCAGTAATGGTAACACTTAATACTATAGAATTTGGTTGATAATAGACTT
TTAAAGAAAGAGTACACTCCATCTTAAGCAAAGTTAGCCTACATACTTTATCTTAGTAAG
TAAGATTTGTTTATGAGTACAATATTTAGAGATGTAAAATACCAAAGAATCAAAATTAAA
ACACTAAATGACACACTTTCTTCTAAAGAAAAATATGAGCAAATGATTTAATAAAATTAA
CAAATTCCCATTAAAGACGAGATACTTTTAGCAATAAACCCATCTAATATTCTGATGTGC
GATTCTATAGGTTTAAATAGACCAAAAAGAAGAGTGCAAATTAAAAATATCTAAAAATTT
TGCTGCACTGAGAAGGAAGTTATAGTAATATCTCATGATAATACAAAACATATTTTTGAA
ACTCCCCAATACTGTAGAGAAATAGCTTTCTTAATTCGCTCTTACTTGAGAATATTTTAT
TAAAAATAATAGTAACAACAATAATAAGAAAAAAGTCAATGA

>TTHERM_00112430(gene)
CAATAATTTTAATAGATAGATATGTTTTTATGAGTTGATAAGATCCATTAATTAATTGAC
TAGTAATCAATCAAAAAGATTAGAGATTAAAGCTTTTTATTAATTGGAATTTAACTAAAA
GATATAGCAATTAATTAAAAAGCATTAAAAGGAAGAAATAAGAAATAATATAGATATATT
CTAAAGTAGTCTGAATATTCTAATTTTTTAAAAATTAGCATAGCATAATATTATATAAAT
TGTACAATATACTAGTTTATTTATTATCAATAGTTTTTATTTAGTAAAAATAAATATAGT
TTTTTCCTAGTTTGTTTTATGAATAAAAGTTATTAAGAATGGATTAATCCTAATGTAGAG
TGTTGGGTTTGGCTCAAATATGAAAATTCTTAGCAAAATTAAAACAATTCTGAAAATGGA
TAATATTTCTAGTGCGTTATTCAATCAGTATAAAAAGAAAAGAATTTAGCAAAGATAAAA
GTTACTTGTAAAGAAGAATAATTAGGAAATCGAATATCAGATTAAGCAATTAATGGATAA
TTAGATGTTTAATTTGAAAGATTATTAGAAAAGGAAATTATGGTTGATTCTCTTCAAACT
TTAGGTTATTCAGATATGGTTCATATGAAGTATTTAAATGAGGCTGAAATAATCAATAAT
TTGAGAAAGCGATATTAAAATAATATGATTTTCACATATATTGGACCAACTTTGGTAGTT
ATGAATCCATATAAAGAAATAGAAGGAGTATAAGATAATCAAGTAATAGATAAAATAAAA
TCTGATCTAGGCATAAAATTTGAAGAGGATTTCAAAATGAATAATCTGAGCACCAACTAA
AATATTATAAACACACCTCATACATATACTGTAAGCGGATTAGCCTACAAATAAATGTTT
AGCAATAAGAAAAATTAAGCAATAGTTATATCAGGCGAAAGTGGAGCAGGTAAAACAGAA
AATGCTAAATTATCGATGCAATTTTTAACAAGTTTGAGTTCAGGGTCTGATAAATAAAAT
GATTTACTCAATTAATTAAAGACTCAAACAGCTAAGAATATTCTATTAGAAGAGTTTAAC
TAATTTGCAATAGAAGTAAAAATACTTGCTTGTAATCCTATTCTAGAAGCTTTTGGTAAT
GCTAAAACAGTAAGAAATAATAATTCCTCTAGATTTGGTAAATACGTAAAAATCTACATA
GATAAAACATCTTAAAAGATAAATGGAGCCTCCATTGATAGCTACTTACTCGAAAAGAGC
AGAATACCTTGTCCAGGAAAGGGAGAGAGAAATTATCACATTTTTTACCACATGCTAAAA
GGAAATCAAGAACTATCTAATTTGAGATTGAGTTAGTTCAAAAATTTATCTGATTTTGAT
TATCTAAAGAAAAGTGACTGCTTTGAGGTTGAGAACATTTAAGATGCTAAACTCTATTTG
GAAGTAAAGAAGTCCTTCAGATAAATGAATTTCTCTAACTAAGAGTAAGAAGCTATATTT
TCTCTAATATCTGCGATACTACTGTTAGGCAATGCAAATTTAGACTCATCAAAAGCTAGC
GACACTCAGGCTCCAACTTTTTTGAACATGAGTTTACCGACACATCATAAAGAATTCAAA
AATGCCTCTGAGTTACTCTAAGTTAATCCTAAAGACCTTGAAGAGTCTTTAGTATTTAAG
GTAAGGAAAGTTGGAACTACAGTAATTAAATCTCCATAAACTGCTGAAGAATGCTTGTCT
ATGAGAGACAGTCTAAGTAAAAATCTATATGATAGTCTTTTTAACTTTTTGGTTTGGAAG
TTAAATTAAAATTTGTTGCCACCTTAAGATTTGCTAAATAAATCATTAAGCATAGGCCTT
TTAGATATATTTGGTTTTGAGAGCTTTGATATAAACTCATTTGAGCAGCTTTGCATTAAT
TTTACCAATGAAAAATTTTAGTAATTGTATGTTTAATATGTTTTCAAAAGCGAAGAAGAA
GATTATAAATAAGAAGGAATTTTGGATGTATTTTCTGATTTATAATATTAAGAGAATTAG
CTCATTATTGATACAATTGAAAAAAAACCCAATGGAATCATGGTGCTTTTAGATGAAAAT
TGCTCATTGGGATCAGGGACGGATGATTCTTTTTTAAATTAAATTACAAAAAACCACTCT
AAAAATCAACTTGTCAGCTTCCCTAAAAAAGATAAATATTCTTTCAGCCTTAGTCATACA
GCAAAACAAGTTGTATATGATGTGCGCGGATTTAGAGATAAAAATAAAGATGAAGTGAGT
ACCGAAGTAGAAAAATGTCTTTAAAGTAGTAAATGTCCAGTTATTGCGAATTTATTATCT
TATTAAGGGTCTTAAACTTAGTAGAATAAAGAAACTTAAAATCTTCAAAATTTTGGAAAT
AATTTAAATTTTAAAAAAGCTGAAATTAGTAATCAAATGAACTCAAGTAAAAAGAATGTA
AAGTTTCTAGGCTAAAAATTTAGATAATCTTTATAGGAATTAATGATAGAATTGAATAAT
AGCGATGTTCACTTCATAAGATGTATAAAACCAAACGAAGAAAAGAAAAAGAATTTTTTT
AAGTATGATTATGTTTATTAGCAAGTACAGTATTTAGGCATACTTGATTCCATTAAAATC
CGCAAAGTTGGATATTCTTACAGAATGACTTATGAAAACTTTTTCTTAGAATACCAAGAA
CTGGGATAGAAAACAAAAGGATTAACATTGTAGAAGGTTTAGCAATAAAAGTTAGATTTA
AAATAATTAATTACAACAGAAATATTTGAAAAGACCAATTTATTGCAAAATAAATAACTT
CCTTAGAAATGTGTAGCATTTGGAAAAACAAAAATATTTCTCAAAAATGAAGTTATGAAG
ATTTTGCATGAAAAAATTTAAGAAATTATTTAATAAAGAAAAAAATATGCAAAGCGAATT
ATTGTCTCAATTTAAAAATATCTGTTTAGGAAATACTTCCATAAGAATTTAATGAAAATA
AAAAATTAATTAATTAAATTGCAATCATTTGCTAGAATGGCTATTTAAAGATAAAAATTC
CTAAGGAAAAAGAAATCAATATTAAAAATGAAGAAGCTTATTAGGCTAAGAATGTTGGGA
TAAGGAATCTCTGCATTTAGGTTAAACTATATCTCATTTGTGTGGGATTTGGTTTGTTTT
ATGATATTTGATAAAACAAATATTCATATTGCATTTTAGTAAATTAAATATTATCGTAAC
CCAAATAAAACTAAGCCTGTTGTTCAAAATTAAACATCTACAATTTAGTAAAATAAATAG
TAAAATCAACAACCTTAAAAAAGCCAAAATTAAGTTACTTCATCATTTTAAGTAAATAAT
TAAATGATGCAATAAAAATAAAGTCTTGTAGGCCAATAAATTTAATCTATTGTAAACGAG
CTTAATTTAGGTGAGATATAAATTAATAAAACCTAACAAGATTTAAAAGACTTTAGAAAA
TCAAAGATTATACCTTAAGTTAACTTGAATCCATCACATAGTAGTAAGAGGGCCAGCAAT
GCTTGGAGATAAACCCTAATTGCAAGTAGTAGTTAAAATAAAATTAATAAAGATTTGTAG
CTATCTGAATTAGGAGAGTAGAAGCTGATAAATATGAAAGAAACAACTGACTAAAAAGAA
AAAATTAAATATACTAAACCTCTGATATTATAATTTACAGAGTATAACCCTGCTTATTAG
TATGCAGAGTTTAATATGGAGAGTGCAATAGATTTAGAAGATGTTCCTAATAGTTTAGAT
TTTGAGGGTGAATTAAATGATTTGATAAGTGAAGAAATCATTCAATAAATAAAAAAAAAT
AACTTTTATTCACACCTTTCTTTTATTCTTGCAAAAAGAACAAAATGGGGAATCACACAA
ACTTAAGAGAAAATAATGAGGCACTAGCTTAAACCAATTTCAAATCCACTAACAAATATT
GCTGATTTGAAGAATATAATCACCTATGAAGACACAAAAGATGCTGTTTAATCAATTAGG
AGTATTATTCAATAAAATAATTTATATAATGACACATCAACATAGACTTAAAGACCAATT
AATTATGAAGATGCTAGAACTGGAAAATTAGATAAGTAAGTATCTAAATAAATTACTAAC
GATTAATCACAAAAATTAGCAACTGTCTTTTCGAAATATTCTCTGATGAACCCAAGAAAA
GCTAGTGTTAGAGACACAAACTCACTTGAACAAATTGTCCTATAATAAAGAAAACTTACA
AAATTAATTTAGTATAAAAAATTTTCTCCTTCAGAAAAAGCTATTAACATATTTAAAACT
CTCTTAAAGTGCACAGGAGAAAGAAAATCCCGATATAACAGACACAACAATATCATAAAG
CTTCTTACCCTTTGTAACGAAGAGTCAATCGACCTAAAAGAAGAAGTTTACGTTTAATTA
TGCAAATAATTAAGTGCAAATGATAAAAAGGAGTCAAGAATAAAATATTTAAAGCTGTTT
GCTATTATAAGCAGCATACTGCCAACAACCAGTAGATTTTATTATCCTTTACTTCACTTT
TTATATATGAGAAATACAGATACTCAAATAGAATAGGATGAGAGAAAATGGTACTAATAC
TGTTTTCAAAGAATTTATAAAAGTGAGTAAATACAAAGAGGATGCATCCCAACTGATACT
GAAATTGTAATGATTGAGAATAAGAAACAAATTTTGATTAGAGTTTATCTTCTAAATGAA
ATCCCAATTACTGTAGGAGTAGAAAGCTATACTAGTGTGAAGATGCTTAAGCAGGAGCTA
CTTTAGAAAATAGGTATAACCTAAAGACATGAATATTATGGCCTTATGGAAGTAAGAAAC
AATATTAAGAAAAAGAGAAAAGAAACGAGATTTATAGATGAAAGTGAGAGAGTAATGGAT
GTGATAGCTTTTTGGGAAAATGAGTAGTATTTATTTGGATCTCAATTAAATTCTTCTTTC
ATACATAGCAACTCAAAATAAAATGATGAAGGTATTGAGCAATTCAACCTTTAAAATTAT
TAGGATCTTGAAGGACTTAAAATTTACCTTGGAATCAGAATACTTTTTTCATTTTAAGAA
AACGATAAAGAAGCAATAAGCGTTTTCTACACTTAGCTATCTTCAGAAGTACTTGAAGGA
AAGTATGCACCTTTGGAGGAAAAAGATTACTTGAATTTGGCTGCTTTATAACTGTGCATA
GATTTTCCAAGAGACGTCATTTTAAAAGAAATATCTAAAAGATAGAGTATCAATGCAGAT
AGTGGGTCTCCATAAAGAACATAGAGTAATTTTTTGAGTGCTACTAGCTAAAGTGAAAGC
GGTGCATCACAGCTTAAAAAGCTTTCTTATTAAGATATTGAACAGATTGATGAATAAGAT
GAATACGAACAATTCATATAAAATAGAAATGAAATTTTAATTGATCCGGTTTTTTACATA
CCAGCTAAAATGTATTTCTAAAAAGATATTCAGTAATGGTAACACTTAATACTATAGAAT
TTGGTTGATAATAGACTTTTAAAGAAAGAGTACACTCCATCTTAAGCAAAGTTAGCCTAC
ATACTTTATCTTAGTAAGTAAGATTTGTTTATGAGTACAATATTTAGAGATGTAAAATAC
CAAAGAATCAAAATTAAAACACTAAATGACACACTTTCTTCTAAAGAAAAATATGAGCAA
ATGATTTAATAAAATTAACAAATTCCCATTAAAGACGAGATACTTTTAGCAATAAACCCA
TCTAATATTCTGATGTGCGATTCTATAGGTTTAAATAGACCAAAAAGAAGAGTGCAAATT
AAAAATATCTAAAAATTTTGCTGCACTGAGAAGGAAGTTATAGTAATATCTCATGATAAT
ACAAAACATATTTTTGAAACTCCCCAATACTGTAGAGAAATAGCTTTCTTAATTCGCTCT
TACTTGAGAATATTTTATTAAAAATAATAGTAACAACAATAATAAGAAAAAAGTCAATGA
GTCTCTGTTCCTTTTATTTATAAGTAACAGAACATTTCAAAAAATAATATATTCTCTTGT
TTCAATATTCTATTTATTTAATTTAAATATAAATTACCATTAAGTCTTCTTAATATATAT
TGTTTATATACTAGTTATTTTAATAATTTTAAAA

>TTHERM_00112430(protein)
MNKSYQEWINPNVECWVWLKYENSQQNQNNSENGQYFQCVIQSVQKEKNLAKIKVTCKEE
QLGNRISDQAINGQLDVQFERLLEKEIMVDSLQTLGYSDMVHMKYLNEAEIINNLRKRYQ
NNMIFTYIGPTLVVMNPYKEIEGVQDNQVIDKIKSDLGIKFEEDFKMNNLSTNQNIINTP
HTYTVSGLAYKQMFSNKKNQAIVISGESGAGKTENAKLSMQFLTSLSSGSDKQNDLLNQL
KTQTAKNILLEEFNQFAIEVKILACNPILEAFGNAKTVRNNNSSRFGKYVKIYIDKTSQK
INGASIDSYLLEKSRIPCPGKGERNYHIFYHMLKGNQELSNLRLSQFKNLSDFDYLKKSD
CFEVENIQDAKLYLEVKKSFRQMNFSNQEQEAIFSLISAILLLGNANLDSSKASDTQAPT
FLNMSLPTHHKEFKNASELLQVNPKDLEESLVFKVRKVGTTVIKSPQTAEECLSMRDSLS
KNLYDSLFNFLVWKLNQNLLPPQDLLNKSLSIGLLDIFGFESFDINSFEQLCINFTNEKF
QQLYVQYVFKSEEEDYKQEGILDVFSDLQYQENQLIIDTIEKKPNGIMVLLDENCSLGSG
TDDSFLNQITKNHSKNQLVSFPKKDKYSFSLSHTAKQVVYDVRGFRDKNKDEVSTEVEKC
LQSSKCPVIANLLSYQGSQTQQNKETQNLQNFGNNLNFKKAEISNQMNSSKKNVKFLGQK
FRQSLQELMIELNNSDVHFIRCIKPNEEKKKNFFKYDYVYQQVQYLGILDSIKIRKVGYS
YRMTYENFFLEYQELGQKTKGLTLQKVQQQKLDLKQLITTEIFEKTNLLQNKQLPQKCVA
FGKTKIFLKNEVMKILHEKIQEIIQQRKKYAKRIIVSIQKYLFRKYFHKNLMKIKNQLIK
LQSFARMAIQRQKFLRKKKSILKMKKLIRLRMLGQGISAFRLNYISFVWDLVCFMIFDKT
NIHIAFQQIKYYRNPNKTKPVVQNQTSTIQQNKQQNQQPQKSQNQVTSSFQVNNQMMQQK
QSLVGQQIQSIVNELNLGEIQINKTQQDLKDFRKSKIIPQVNLNPSHSSKRASNAWRQTL
IASSSQNKINKDLQLSELGEQKLINMKETTDQKEKIKYTKPLILQFTEYNPAYQYAEFNM
ESAIDLEDVPNSLDFEGELNDLISEEIIQQIKKNNFYSHLSFILAKRTKWGITQTQEKIM
RHQLKPISNPLTNIADLKNIITYEDTKDAVQSIRSIIQQNNLYNDTSTQTQRPINYEDAR
TGKLDKQVSKQITNDQSQKLATVFSKYSLMNPRKASVRDTNSLEQIVLQQRKLTKLIQYK
KFSPSEKAINIFKTLLKCTGERKSRYNRHNNIIKLLTLCNEESIDLKEEVYVQLCKQLSA
NDKKESRIKYLKLFAIISSILPTTSRFYYPLLHFLYMRNTDTQIEQDERKWYQYCFQRIY
KSEQIQRGCIPTDTEIVMIENKKQILIRVYLLNEIPITVGVESYTSVKMLKQELLQKIGI
TQRHEYYGLMEVRNNIKKKRKETRFIDESERVMDVIAFWENEQYLFGSQLNSSFIHSNSK
QNDEGIEQFNLQNYQDLEGLKIYLGIRILFSFQENDKEAISVFYTQLSSEVLEGKYAPLE
EKDYLNLAALQLCIDFPRDVILKEISKRQSINADSGSPQRTQSNFLSATSQSESGASQLK
KLSYQDIEQIDEQDEYEQFIQNRNEILIDPVFYIPAKMYFQKDIQQWQHLILQNLVDNRL
LKKEYTPSQAKLAYILYLSKQDLFMSTIFRDVKYQRIKIKTLNDTLSSKEKYEQMIQQNQ
QIPIKDEILLAINPSNILMCDSIGLNRPKRRVQIKNIQKFCCTEKEVIVISHDNTKHIFE
TPQYCREIAFLIRSYLRIFYQKQQQQQQQEKSQ