Identifiers and Description

Gene Model Identifier

TTHERM_00112550

Standard Name

TKT1 (TransKeTolase)

Aliases

PreTt27069 | 8.m00329 | 3812.m02366

Description

TKT1 pyridine-binding domain transketolase; Transketolase; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• catalytic activity (IEA) | GO:0003824

Biological Process

• metabolic process (IEA) | GO:0008152

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_5405	0
	Description: None
WormBase	WBGene00008506	9.997093137033517e-262
	Description: locus:tkt-1 status:Confirmed UniProt:O17759 protein_id:CAB02889.1
Tetrahymena borealis	EI9_03959.1	9.997093137033517e-262
	Description: transketolase, pyridine binding domain-containing protein (652 aa)
SGD	YPR074C	9.000270655364168e-50
	Description: TKL1 Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
DictyBase	DDB_G0272618	3.9990760533890984e-36
	Description: tkt-1 on chromosome: 2 position 2357975 to 2360086
Oxytricha	Contig9079.0.0.g83	0.0004000184047659232
	Description: Dehydrogenase E1 component

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00112550(coding)
ATGAATACAAGAAGCGGCAAAAAATCTAGTGCCTCCAACTCCAAGCCCGAAACCACCACT
TCTACCACTAAGAATTCTACCAATAAGAAGGTTAAGGCCAACGAAGAACATGACATCGAA
GCTCTTCAAGACGTTGCTAACAGATTGAGAATTCTTTCCATGAAGATGACCAACGCCTCT
AATAGTGGTCACCCTACCAGTTGTGCATCTATGGCTGAATTCCTTTCAGTTATGTTCTTC
GACAAGTCTGGTATGAGAATCAAGAGTGATAACCCCAAGTCATTTGTTGCTGACAGATTA
GTTTTATCTAAGGGCCACACTGCCCCTATTTTGTATGCTGCATGGGGAATTGCAGGCTTA
TACACTGAAGAATAATTAATGACCCTCCGTAAATTCGACTCTGATTTAGAAGGTCACCCT
ACTCCTAGACTTCCCTTCGTCGATGTTGCTACTGGTTCTTTGGGTCAAGGTTTAGGTGTT
GCTTGCGGTATGGCTTATACTTCTAAATACCACGACAGCCTTAACAACCGTTTCTGGTGT
ATCCTCGGTGATGGTGAATGCGCTGAAGGTTCTGTTTGGGAAGCTGCTCACTTTGCTGGT
ATTTACAAGTTAGATAACTTGATTGCTGTCGTTGATGTCAACAGATTAGGTTAATCTGAA
GCTACCTCTTTGGGTCATAATACTAACGTTTATAAGAAGAGATTCGAAGCCTTTGGCTGG
AATGCTTTGGTTGTTGATGGACACGATATTGAAGCCCTCATTAAGGCTTTCAATGAATGC
AAGCACAAGGCTAACTAACCCAGTATCATTATTGCTAAGACCTTAAAAGGAAAGGGTCTT
CCTAATATTGAAGACTAAGAAAACTGGCACGGTAAGCCCGTCGGCAACAAGATTGACGAT
TTGATCAAGCACCTTGAAGAATAGCTTGTCGATAAGAACAGAAAGCTTACTACCATCCCC
CCTGAGAATGCTGAAGAAATTACTCTTCATTCAGATGCAATTAAATTACCCGAACTTAGC
TACAAGAAAGGACAACAAGTTGCTACCAGATTCGCTTATGGTGATGCCTTGAAGAGACTC
GGTGGTGTTGACACTTACAGAAGAATTTGCTCTTTGGATGGTGATACCAAGAACTCTACT
TATGCCCTTACTTTCAAGAACGCATTCCCTGACAGATTTGTTGAATGCTACATTGCTGAA
TAAAACTTAGTCTCTGTTTCTATTGGTTTATCTGCCAGAAACAAGATTCCTTTTGCCTCC
ACTTTTGGTGCTTTCTTCTCTAGAGCTTACGATCACATTAGAATGGCTGGTGTTTCTAAG
GTTAACATTAAATTAGTAGGTTCTCACTCTGGTGTTTCTATTGGTGAAGATGGTCCTTCA
TAAATGGCTTTGGAAGACTTTGCCATGTTCAGAGCTATTCCTGATGCTGTCGTCCTCTAT
CCTTCTGATGCTGTTTCTTGTGAAAGAGCTGTTGAATTAGCTACTAATCATCACGGTATC
GTATACATCCGTACTTCAAGACCTGCTACTGAAGTAGTTTATGATAACCATGAAGAATTC
CATCTCGGTTAGTCTAAGGTACATGGTAAGACTGATTCTGATAAGATTCTTATTATTGGT
GGTGGTATTACATTCGAATCTGCCATGAAGGCTCAAAAAACTTTGGCTGCTGAAGGAATC
CACGCTAGAGTTATGGATATCTTTTCTATTAAACCTATTGATAGAGATGGTATCATCAAC
AATGCTAAAGAATGCAATAATACTATCCTCACTGTTGAAGATCACTACATCGAAGGTGGT
ATCCATGAGGCTGTTTGCAATGCTGTTGCTTCTCTCGGTAGCATCAAGGTTCACGCTATT
GCCGTCGATAGCGTTCCTAGAAGTGGTACTCCTGAAGATCTCTTAAATCATTATAAACTT
ACTGCTCCTCACGTAGTTGAAAAGGTTAAGAGCATCCTTCAATGA

>TTHERM_00112550(gene)
ATGAATACAAGAAGCGGCAAAAAATCTAGTGCCTCCAACTCCAAGCCCGAAACCACCACT
TCTACCACTAAGAATTCTACCAATAAGAAGGTTAAGGCCAACGAAGAACATGACATCGAA
GCTCTTCAAGACGTTGCTAACAGATTGAGAATTCTTTCCATGAAGATGACCAACGCCTCT
AATAGTGGTCACCCTACCAGTTGTGCATCTATGGCTGAATTCCTTTCAGTTATGTTCTTC
GACAAGTCTGGTAAGCTTAAAACCCAAAGCATTAACTTTACGGCTATATCTTCTTACAGT
TTATTAAAGAAAAATGTTATTAATTGACATTCAGAAACTCTTTTTAACCTAAATTTAAAC
TTAATAGCCATCTGATTTTTATTTTAAATTTTTTATATGAATTTATAAAAATGAAGATAA
ATGATGTATTTATACTTCGTAACTTCATTTAATAAATCATTTCTAAATGGAGAAATGTGT
TTAATCAATTTTTTGTTCATAATTTAGGTATGAGAATCAAGAGTGATAACCCCAAGTCAT
TTGTTGCTGACAGATTAGTTTTATCTAAGGGCCACACTGCCCCTATTTTGTATGCTGCAT
GGGGAATTGCAGGCTTATACACTGAAGAATAATTAATGACCCTCCGTAAATTCGACTCTG
ATTTAGAAGGTCACCCTACTCCTAGACTTCCCTTCGTCGATGTTGCTACTGGTTCTTTGG
GTCAAGGTTTAGGTGTTGCTTGCGGTATGGCTTATACTTCTAAATACCACGACAGCCTTA
ACAACCGTTTCTGGTGTATCCTCGGTGATGGTGAATGCGCTGAAGGTAATTTTATACTTT
TAATTCAGATTTTTAGAGGTTAAAAATAATATTTATGAAATCCATTTCATATCATATTCC
ATTGAATAAAATCTACTTATTATTTGCAGAGATAACTTGTTTTAATTTCAAGTGTCTAGA
CTTTGTTTCTACTGCATAGGAAGATATCTTCTTTAAAAGCATTTTCAAAGAGAAAAATCT
ATAATAAATTTATTATCTTTGTGTATAGACTGCGATTTGGTATGACAGATAACAAAAAAT
TTGAAATAGAGTGTAAAAAAGCACAAAAATACAAAAAAATGAAAAAATATCTTTCGCATT
TTACTAACTCTACTTTGTAAATTTATTAATAGAACAAATTAAGGATTTTTTATTATTTTT
AGATTTTATTTGAAAAAAATTGATAGTTATTTTGAGAGATATCTATTTATCTATCAATCT
ATCTATTTAGCTAATAAGCTAATATCTATTTGCTTGCTTTAAAATGATCAATTCAAGCTT
TTATACACTTGATAGAACTTTTGTCTATTTAATATATCAAAATTAATGATTTTCATTCAA
AGATATATTTGTTTAGTTTTAAAAAGAGCATAAAATTATGGAATCGAAGCAAACAAATAA
ATGTTAATTACGATTTACTCATTTTTTCTTAATTGGAATACTTTAAAAGAAATCAAAAGA
AGCACACACACAATCAGAAAATAAAAGTCTATTTTTTAATTTGCTTTAATAAGAAATGTA
AATAATACAAGCTTTACATAGAATTGAATGATAATTAGTTCAAGTTAAGCTTTTCTAGAA
ATTTTAATCAGTAAACACCGCAAATCAAAAACTTTTTTCAATTTTATTAAAATAACCTCA
AATTAAATCTTAAAAATTGCATTAATTTAACTAACATCTTTTAATTACTAATATAGGTTC
TGTTTGGGAAGCTGCTCACTTTGCTGGTATTTACAAGTTAGATAACTTGATTGCTGTCGT
TGATGTCAACAGATTAGGTTAATCTGAAGCTACCTCTTTGGGTCATAATACTAACGTTTA
TAAGAAGAGATTCGAAGCCTTTGGCTGGAATGCTTTGGTTGTTGATGGACACGATATTGA
AGCCCTCATTAAGGCTTTCAATGAATGCAAGCACAAGGCTAACTAACCCAGTATCATTAT
TGCTAAGACCTTAAAAGGAAAGGGTCTTCCTAATATTGAAGACTAAGAAAACTGGCACGG
TAAGCCCGTCGGCAACAAGATTGACGATTTGATCAAGCACCTTGAAGAATAGCTTGTCGA
TAAGAACAGAAAGCTTACTACCATCCCCCCTGAGAATGCTGAAGAAATTACTCTTCATTC
AGATGCAATTAAATTACCCGAACTTAGCTACAAGAAAGGACAACAAGTACAAAAATAATT
TTAATTACAATATTTTCAATAAAATTTATTTTTCTTGGCTAACATCTTATTTAATTTTAA
TAAAAGGTTGCTACCAGATTCGCTTATGGTGATGCCTTGAAGAGACTCGGTGGTGTTGAC
ACTTACAGAAGAATTTGCTCTTTGGATGGTGATACCAAGAACTCTACTTATGCCCTTACT
TTCAAGAACGCATTCCCTGACAGATTTGTTGAATGCTACATTGCTGAATAAAACTTAGTC
TCTGTTTCTATTGGTTTATCTGCCAGAAACAAGGTAAAAAATATAATACAAATAAAATTA
GCAAAATAAAAAAGATTATTCCTACCTAGATTTTTAATAGCTTAATATAATCAGTTTTTA
ATAGAGCATAAATAAAATAAAATAATATAATATAAAGAATAGATTTTATTATAAAAATAT
ATATTTAGTTGATTAGAGCAATTATTAATAAGTTAAAGAAAGCCCATATTTATTTATTAG
TTAAAGAAAATAAGCAAGCAAAAGCAAATTTATAAAGGAATTTAAAAACCAAATTGCATT
AATTAGCTTCTAAAATTATTTTTTTAAATTTAATGAATTTATTTATTTATTTGTATGATA
GATTCCTTTTGCCTCCACTTTTGGTGCTTTCTTCTCTAGAGCTTACGATCACATTAGAAT
GGCTGGTGTTTCTAAGGTTAACATTAAATTAGTAGGTTCTCACTCTGGTGTTTCTATTGG
TGAAGATGGTCCTTCATAAATGGCTTTGGAAGACTTTGCCATGTTCAGAGCTATTCCTGA
TGCTGTCGTCCTCTATCCTTCTGATGCTGTTTCTTGTGAAAGAGCTGTTGAATTAGCTAC
TAATCATCACGGTATCGTATACATCCGTACTTCAAGACCTGCTACTGAAGTAGTTTATGA
TAACCATGAAGAATTCCATCTCGGTTAGTCTAAGGTACATGGTAAGACTGATTCTGATAA
GATTCTTATTATTGGTGGTGGTATTACATTCGAATCTGCCATGAAGGCTCAAAAAACTTT
GGCTGCTGAAGGAATCCACGCTAGAGTTATGGATATCTTTTCTATTAAACCTATTGATAG
AGATGGTATCATCAACAATGCTAAAGAATGCAATAATACTATCCTCACTGTTGAAGATCA
CTACATCGAAGGTGGTATCCATGGTAATAATATATTTTTTTTTAGAAATTAATTTTTATT
TAATTGAATTTCTTTAATTAATAACAGAGGCTGTTTGCAATGCTGTTGCTTCTCTCGGTA
GCATCAAGGTTCACGCTATTGCCGTCGATAGCGTTCCTAGAAGTGGTACTCCTGAAGATC
TCTTAAATCATTATAAACTTACTGCTCCTCACGTAGTTGAAAAGGTTAAGAGCATCCTTC
AATGA

>TTHERM_00112550(protein)
MNTRSGKKSSASNSKPETTTSTTKNSTNKKVKANEEHDIEALQDVANRLRILSMKMTNAS
NSGHPTSCASMAEFLSVMFFDKSGMRIKSDNPKSFVADRLVLSKGHTAPILYAAWGIAGL
YTEEQLMTLRKFDSDLEGHPTPRLPFVDVATGSLGQGLGVACGMAYTSKYHDSLNNRFWC
ILGDGECAEGSVWEAAHFAGIYKLDNLIAVVDVNRLGQSEATSLGHNTNVYKKRFEAFGW
NALVVDGHDIEALIKAFNECKHKANQPSIIIAKTLKGKGLPNIEDQENWHGKPVGNKIDD
LIKHLEEQLVDKNRKLTTIPPENAEEITLHSDAIKLPELSYKKGQQVATRFAYGDALKRL
GGVDTYRRICSLDGDTKNSTYALTFKNAFPDRFVECYIAEQNLVSVSIGLSARNKIPFAS
TFGAFFSRAYDHIRMAGVSKVNIKLVGSHSGVSIGEDGPSQMALEDFAMFRAIPDAVVLY
PSDAVSCERAVELATNHHGIVYIRTSRPATEVVYDNHEEFHLGQSKVHGKTDSDKILIIG
GGITFESAMKAQKTLAAEGIHARVMDIFSIKPIDRDGIINNAKECNNTILTVEDHYIEGG
IHEAVCNAVASLGSIKVHAIAVDSVPRSGTPEDLLNHYKLTAPHVVEKVKSILQ