Identifiers and Description
Gene Model Identifier
TTHERM_00123780Standard Name
Aliases
PreTt27292 | 8.m00552 | 3812.m02580Description
Transient receptor potential cation channel subfamily VGenome Browser (Macronucleus)
Genome Browser (Micronucleus)
External Links
Gene Ontology Annotations
No Data fetched for Gene Ontology Annotations
Domains
- ( PF08016 ) Polycystin cation channel
Gene Expression Profile
Vegetative Cell Cycle (Zhang et al., 2023)
GeneMania
Tetrahymena Stock Center
No Data fetched for Tetrahymena Stock Center
Homologs
No Data fetched for Homologs
General Information
No. Gene Name(s) Paragraph Text 2324 (no standard gene name) This protein is a homolog of proteins in the polycystic cation channel transmembrane protein family. It contains one domain; the domain (E-value = 1.2 -10) is known as CL0030, which contains the cation channel region of PKD1 and PKD2 proteins. PKD1 and PKD2 functions through a common signaling pathway that is necessary for normal tubulogenesis. Tubulogenesis is the formation of tubules in epithelial or endothelial cells that transport liquid and gas throughout the body. In humans, the mutations in PKD1 and PKD 2 form thousands of cysts which inhibits the protein from efficiently carrying liquid and gas throughout the body. It is possible that in Tetrahymena this protein is an integral membrane protein. Paragraph by: Deborah Yi-an Lin, Keck Science Department, Scripps College 2330 (no standard gene name) This protein is a homolog of proteins in the polycystic cation channel transmembrane protein family. It contains one domain; the domain (E-value = 1.2 -10) is known as CL0030, which contains the cation channel region of PKD1 and PKD2 proteins. PKD1 and PKD2 functions through a common signaling pathway that is necessary for normal tubulogenesis. Tubulogenesis is the formation of tubules in epithelial or endothelial cells that transport liquid and gas throughout the body. In humans, the mutations in PKD1 and PKD 2 form thousands of cysts which inhibits the protein from efficiently carrying liquid and gas throughout the body. It is possible that in Tetrahymena this protein is an integral membrane protein. Paragraph by: Deborah Yi-an Lin, Keck Science Department, Scripps College
Associated Literature
No Data fetched for Associated Literature
Sequences
>TTHERM_00123780(coding)
ATGAGTCAAAACAAAAAGCTCAATCTTTTAGATACCTTGCAGCCTGTTTCTGCAGAAAGG
TTTATCTCTTCTCGAAATACTTAGAAGGGATTTGAGCTCGCAAGTCCATCTGTTTAATCT
AATTTTTTTGAGGATTAGATTTTAAACATAGAGAACTAGTTGGATGAATATTTAGAGCTA
ATGGAAAATAAAATGAAAGAAATAAGCGAACAAAGATTATAAGATAATTTGTAATTTATG
AATGAGCTAAAATTCATAGTTGCAGAAAGCAAAAACAATTAGTAAAAAAAAGAAGGAGTT
TTTAAAATACTATCATTATTTTTAAGCTATTATGGATGCTGGAGAGAAGCAGAAACCTTA
ATGAGATAAATATAAAGCAATAACAACTTAGGAAGTAGGGGAGGAAGCTAACCAAAAAGA
GAAGTTTATGATATATATGATTTTATTTTGGAGCTTATTGAAAATGAGAATGAAATGAGC
AAAATGATGAAAGTTTTGTTTTCATAGGAAAGTAGAATCTAATAGGAACAAAGAGAATAA
ATGGATACATCTTCTTAAATTTACAATTTTAAATAAAATATATTTTTAGCTATTATACAA
ACATTTAACATAAGAATGAATTCAATAAATGATGAGATATTCAGCTGGCTAATAGACAAC
TAAAAACTCAGGATAATTGAGATAATTTTAGAAAATGACAGATTTAGCGCATCATTAAAA
TAAGGCAATTATTAAAGAATGAAAAAACAAGAAAGAAAAATGCTGAAATACTTGCATCAG
AATTTAATTTTGAAAAACTACAACAACGAAATTGAGTTGATTTTAAACATGAATGAAAAT
AATTTAGAGCTTTTATCCTCTAAATATGTTCTTTATATTGCTAAATATGAACGTATTCCG
CCTAATTATATATTAAATAGGACTCTAATTAAGTAGGTTGTTTATTAGTAAAATGTACCA
TTAATGTCTGCTATGCTCAAACTAGATAGAGTTATCACTTAGTAAACACTTCATTCAAAG
AAGGTTTAGGCTTAAATTAATGTGTTTCTTTCTTAAGCTGACACTTTTTGTATGGGATTA
TATTTTCTTAAAAAAATGTCTTAAAAAAAGTAAATTATTTCTTAATCATCTGAATATTTA
GAGACCATTTTGAGATTGCTAGAGAAACCTAAAAGCGATGAAAAATTCGCCTTTGAAATT
TTTAGTCATGTGCTTCATCCACTAATTTTATGCTTAGTCGCAAGTAAAATTTTGTTAAAA
CTATCATTCTTCAAAAATCCTTTCAGCTCAGAGATGCTCAAACTAGCAAAATACTATTTG
GAAAGAGCTTTACTGTTTAGAGATACAATTTTTGATGCAAGAGAAATGAGCCTCATTCTC
TTTAAACCCCTTTTCCCTAGCGATAAGCCTTTAGTTAAAGCTTTGAGAAACAGAAATTAC
TGCTAGTTTTTTACAGAGTTTTTTATTCATCCATGCATAACATATCTTCTTGAACAGAAA
TGGATGAGTACGTATGGTTTTGACTACTCACTTTTAAGCACATTTACTCCTTTATGTCAT
TTTTAAAAGTAAGCCAGAATCAAAAATACAATTGCTAAAGGCTCAAAATCATCATCATCT
TCAACAAGTTCATTTTAAAAATCAATGAAATCAACAGGTTCTTCAGCTTCTTTTTCTCTT
GAACCACAGAAATAAAACTGGATAATTTTCAGAGATATTGAGGTCAGTTAACTGAAGAAA
GCAACAAAAAATAATCATTTTTATTAATTTGTTATTTATAACAAATCAGTTTAAGTGAGA
ACTTTTTTCGAGTTTATCCTTTTTCTGGCAATCTTTTGTTTCACTTTATATGAACTATTT
CTATTTATAGAAAATCTAAATAGCTATGCTTCAGTTGATGATCCTGTAAAAATAATGTTA
TTCTCATCAACTGTACCGTAAGATTGGTAAAGTAAAGTGAATGACTTCAAAAAGTAAAAT
CCAACACCACCTCCATTAGATATTTAAATAGATAATACTACAAATCTTAATATTTAAACA
ACAGATCCTTAGATTTTTTGTAAACTAATCTTATACTAAATATCTTCGGGTTATCAAGAA
TTTATGGATTTTTTTTAAAGTTAGTGCGTTAAATTAATTTATGTTGGTACTTAATTTGAA
AAACTCTGTAACGATACAATCAGAGTACTTTGGTTCATTTTCTGTATTGGAGCAAATGCC
ATTTAAAAGCAAATTTATGTATATCTTATAAGACGAAAAACTGATCCCTAAATATTAGAT
TTGTATGATTTACTCCTCTACATAGCTTGTGGCTCATTTTTATTGACAAAGCAAATATTT
ATTCCTGAAGGTATATCTGCTAATTATACTTTTGAATACTTCAACAATTGTTAATTTGCT
TTGAAAATTGAATGCTGTGCTATAGTGTTTATTTTATGGCTTAGAATGTTTATATTTTTA
ATTAGAACTTAAAAATTTGGATTACTAGTCAAAGTAATAATACTATTTACTAAAGACCTT
TTATATTTTATGGTCATTCTTATTACTGTCACAGTCGCTTTTGGGCTAATCAATTACATT
CTTTTTTAAAATAGCCTTGAACTATATAAATCTATTGATAAATCCATATTCAATCTATTT
GCTGCAGCTTTTGGTGCATTCGATTTTAACAATTAAACTGGAATTTAGTCAGCGATTCTA
ATTGTTTTTTTAGTTGTAGTGAATGTTATCCTTCTTAATTTACTAATTGCTATATTAAAC
ACGAGATATGAGAAGACAATGCAACAATCAGAGATGGAATACTCTTTAGTAGTATATAAT
GACTATATTAATTCAAGATTTAACCCTATATACATGTCTATGATTTCACTACCTCCACCT
TTTAATATCCTTAATTTTATATTTGGAATAATTTCTTTTATAACTAAGTCTAGAATATGG
AATAAAATAGCTTTAAAAATTGGATACACATTAGTTATATTTCTTCCTTGTATTTTACTC
TACATAGCTCTTTCTTTGGTTCTCATTCCTTTTTCTTATTTATATTTTATCCATTAAGTA
TCAATGTATTCTTTTTCTGATAATATGATGTATGCCAGAAAGAAAAATAAATGCTTCAAG
ATTACACTTTATTTATTTCGATTACTGACTTGGATTACATTAGGTATTCCTTATTTACTT
GTAGTGTTTTTTTCAAATGATCTGCCTTTGTTTTGTAAATCGGCCTTTGCTCATAACAAT
AATAAGTACAATTTCACTAAAAATCCTGTCCTTGACTTAAGAGTAATAAAGTATGTGTCT
CTTTACTCTAATTATTTAAATTTAGCAAAAAAAGATGTATTTAACTATTTAGAATTTAGG
TCTTCGCTTGAGCAAAAAAAGGAAGTAAAATATAAAAAATCTTACTTTCAAAGATTTGCA
CAACCTTCTATCAAATCTAATAGCTAGCCTCTATAATAAATTAGGAAAGGATTTTAAAAT
AATGTAAAGCATAATTTTAAATCAGAAACCATATTTGAAAAAAATTTTAATGATGCAGTT
AAAAAATTTGGAGATTCTAAAGTAAAATAAGAAGTAGAAAATATCCAGCTTAATAATCTT
TTAAAAGCAATAAAATATTCAGCAATCTTCTTTAAAAAATCAAAGAGTACTTCGTTTAAC
TTGTCTAAACTTCTTTACATTGTAAAGAAAAAAGAAATAAATTTAAATCTTCTGTAATTA
AATACTGATAATTTTTTCTTAAATAGATCATTTAGCTCATAACCTAACATAAATGTTAAT
AACTTAAATTGA>TTHERM_00123780(gene)
AAGAATAGCAACAAAATTTAAAGATCTGTTAATATTGTTTGTATTTATTTAATTGAGTTT
ATAGATTTTATTTTTACTAATTAACAGTAACTTAACTATAATATTTAAAATTAATTATGA
GTCAAAACAAAAAGCTCAATCTTTTAGATACCTTGCAGCCTGTTTCTGCAGAAAGGTTTA
TCTCTTCTCGAAATACTTAGAAGGGATTTGAGCTCGCAAGTCCATCTGTTTAATCTAATT
TTTTTGAGGATTAGATTTTAAACATAGAGAACTAGTTGGATGAATATTTAGAGCTAATGG
AAAATAAAATGAAAGAAATAAGCGAACAAAGATTATAAGATAATTTGTAATTTATGAATG
AGCTAAAATTCATAGTTGCAGAAAGCAAAAACAATTAGTAAAAAAAAGAAGGAGTTTTTA
AAATACTATCATTATTTTTAAGCTATTATGGATGCTGGAGAGAAGCAGAAACCTTAATGA
GATAAATATAAAGCAATAACAACTTAGGAAGTAGGGGAGGAAGCTAACCAAAAAGAGAAG
TTTATGATATATATGATTTTATTTTGGAGCTTATTGAAAATGAGAATGAAATGAGCAAAA
TGATGAAAGTTTTGTTTTCATAGGAAAGTAGAATCTAATAGGAACAAAGAGAATAAATGG
ATACATCTTCTTAAATTTACAATTTTAAATAAAATATATTTTTAGCTATTATACAAACAT
TTAACATAAGAATGAATTCAATAAATGATGAGATATTCAGCTGGCTAATAGACAACTAAA
AACTCAGGATAATTGAGATAATTTTAGAAAATGACAGATTTAGCGCATCATTAAAATAAG
GCAATTATTAAAGAATGAAAAAACAAGAAAGAAAAATGCTGAAATACTTGCATCAGAATT
TAATTTTGAAAAACTACAACAACGAAATTGAGTTGATTTTAAACATGAATGAAAATAATT
TAGAGCTTTTATCCTCTAAATATGTTCTTTATATTGCTAAATATGAACGTATTCCGCCTA
ATTATATATTAAATAGGACTCTAATTAAGTAGGTTGTTTATTAGTAAAATGTACCATTAA
TGTCTGCTATGCTCAAACTAGATAGAGTTATCACTTAGTAAACACTTCATTCAAAGAAGG
TTTAGGCTTAAATTAATGTGTTTCTTTCTTAAGCTGACACTTTTTGTATGGGATTATATT
TTCTTAAAAAAATGTCTTAAAAAAAGTAAATTATTTCTTAATCATCTGAATATTTAGAGA
CCATTTTGAGATTGCTAGAGAAACCTAAAAGCGATGAAAAATTCGCCTTTGAAATTTTTA
GTCATGTGCTTCATCCACTAATTTTATGCTTAGTCGCAAGTAAAATTTTGTTAAAACTAT
CATTCTTCAAAAATCCTTTCAGCTCAGAGATGCTCAAACTAGCAAAATACTATTTGGAAA
GAGCTTTACTGTTTAGAGATACAATTTTTGATGCAAGAGAAATGAGCCTCATTCTCTTTA
AACCCCTTTTCCCTAGCGATAAGCCTTTAGTTAAAGCTTTGAGAAACAGAAATTACTGCT
AGTTTTTTACAGAGTTTTTTATTCATCCATGCATAACATATCTTCTTGAACAGAAATGGA
TGAGTACGTATGGTTTTGACTACTCACTTTTAAGCACATTTACTCCTTTATGTCATTTTT
AAAAGTAAGCCAGAATCAAAAATACAATTGCTAAAGGCTCAAAATCATCATCATCTTCAA
CAAGTTCATTTTAAAAATCAATGAAATCAACAGGTTCTTCAGCTTCTTTTTCTCTTGAAC
CACAGAAATAAAACTGGATAATTTTCAGAGATATTGAGGTCAGTTAACTGAAGAAAGCAA
CAAAAAATAATCATTTTTATTAATTTGTTATTTATAACAAATCAGTTTAAGTGAGAACTT
TTTTCGAGTTTATCCTTTTTCTGGCAATCTTTTGTTTCACTTTATATGAACTATTTCTAT
TTATAGAAAATCTAAATAGCTATGCTTCAGTTGATGATCCTGTAAAAATAATGTTATTCT
CATCAACTGTACCGTAAGATTGGTAAAGTAAAGTGAATGACTTCAAAAAGTAAAATCCAA
CACCACCTCCATTAGATATTTAAATAGATAATACTACAAATCTTAATATTTAAACAACAG
ATCCTTAGATTTTTTGTAAACTAATCTTATACTAAATATCTTCGGGTTATCAAGAATTTA
TGGATTTTTTTTAAAGTTAGTGCGTTAAATTAATTTATGTTGGTACTTAATTTGAAAAAC
TCTGTAACGATACAATCAGAGTACTTTGGTTCATTTTCTGTATTGGAGCAAATGCCATTT
AAAAGCAAATTTATGTATATCTTATAAGACGAAAAACTGATCCCTAAATATTAGATTTGT
ATGATTTACTCCTCTACATAGCTTGTGGCTCATTTTTATTGACAAAGCAAATATTTATTC
CTGAAGGTATATCTGCTAATTATACTTTTGAATACTTCAACAATTGTTAATTTGCTTTGA
AAATTGAATGCTGTGCTATAGTGTTTATTTTATGGCTTAGAATGTTTATATTTTTAATTA
GAACTTAAAAATTTGGATTACTAGTCAAAGTAATAATACTATTTACTAAAGACCTTTTAT
ATTTTATGGTCATTCTTATTACTGTCACAGTCGCTTTTGGGCTAATCAATTACATTCTTT
TTTAAAATAGCCTTGAACTATATAAATCTATTGATAAATCCATATTCAATCTATTTGCTG
CAGCTTTTGGTGCATTCGATTTTAACAATTAAACTGGAATTTAGTCAGCGATTCTAATTG
TTTTTTTAGTTGTAGTGAATGTTATCCTTCTTAATTTACTAATTGCTATATTAAACACGA
GATATGAGAAGACAATGCAACAATCAGAGATGGAATACTCTTTAGTAGTATATAATGACT
ATATTAATTCAAGATTTAACCCTATATACATGTCTATGATTTCACTACCTCCACCTTTTA
ATATCCTTAATTTTATATTTGGAATAATTTCTTTTATAACTAAGTCTAGAATATGGAATA
AAATAGCTTTAAAAATTGGATACACATTAGTTATATTTCTTCCTTGTATTTTACTCTACA
TAGCTCTTTCTTTGGTTCTCATTCCTTTTTCTTATTTATATTTTATCCATTAAGTATCAA
TGTATTCTTTTTCTGATAATATGATGTATGCCAGAAAGAAAAATAAATGCTTCAAGATTA
CACTTTATTTATTTCGATTACTGACTTGGATTACATTAGGTATTCCTTATTTACTTGTAG
TGTTTTTTTCAAATGATCTGCCTTTGTTTTGTAAATCGGCCTTTGCTCATAACAATAATA
AGTACAATTTCACTAAAAATCCTGTCCTTGACTTAAGAGTAATAAAGTATGTGTCTCTTT
ACTCTAATTATTTAAATTTAGCAAAAAAAGATGTATTTAACTATTTAGAATTTAGGTCTT
CGCTTGAGCAAAAAAAGGAAGTAAAATATAAAAAATCTTACTTTCAAAGATTTGCACAAC
CTTCTATCAAATCTAATAGCTAGCCTCTATAATAAATTAGGAAAGGATTTTAAAATAATG
TAAAGCATAATTTTAAATCAGAAACCATATTTGAAAAAAATTTTAATGATGCAGTTAAAA
AATTTGGAGATTCTAAAGTAAAATAAGAAGTAGAAAATATCCAGCTTAATAATCTTTTAA
AAGCAATAAAATATTCAGCAATCTTCTTTAAAAAATCAAAGAGTACTTCGTTTAACTTGT
CTAAACTTCTTTACATTGTAAAGAAAAAAGAAATAAATTTAAATCTTCTGTAATTAAATA
CTGATAATTTTTTCTTAAATAGATCATTTAGCTCATAACCTAACATAAATGTTAATAACT
TAAATTGATTTTTATTTAACTAAGAAAATAATCTTATTTATGTTTGCAAAAATATATTTA
TTTTCTTACAGTCAAAATAATTAATTATTCTCAAAAATTATTTTACCAAT>TTHERM_00123780(protein)
MSQNKKLNLLDTLQPVSAERFISSRNTQKGFELASPSVQSNFFEDQILNIENQLDEYLEL
MENKMKEISEQRLQDNLQFMNELKFIVAESKNNQQKKEGVFKILSLFLSYYGCWREAETL
MRQIQSNNNLGSRGGSQPKREVYDIYDFILELIENENEMSKMMKVLFSQESRIQQEQREQ
MDTSSQIYNFKQNIFLAIIQTFNIRMNSINDEIFSWLIDNQKLRIIEIILENDRFSASLK
QGNYQRMKKQERKMLKYLHQNLILKNYNNEIELILNMNENNLELLSSKYVLYIAKYERIP
PNYILNRTLIKQVVYQQNVPLMSAMLKLDRVITQQTLHSKKVQAQINVFLSQADTFCMGL
YFLKKMSQKKQIISQSSEYLETILRLLEKPKSDEKFAFEIFSHVLHPLILCLVASKILLK
LSFFKNPFSSEMLKLAKYYLERALLFRDTIFDAREMSLILFKPLFPSDKPLVKALRNRNY
CQFFTEFFIHPCITYLLEQKWMSTYGFDYSLLSTFTPLCHFQKQARIKNTIAKGSKSSSS
STSSFQKSMKSTGSSASFSLEPQKQNWIIFRDIEVSQLKKATKNNHFYQFVIYNKSVQVR
TFFEFILFLAIFCFTLYELFLFIENLNSYASVDDPVKIMLFSSTVPQDWQSKVNDFKKQN
PTPPPLDIQIDNTTNLNIQTTDPQIFCKLILYQISSGYQEFMDFFQSQCVKLIYVGTQFE
KLCNDTIRVLWFIFCIGANAIQKQIYVYLIRRKTDPQILDLYDLLLYIACGSFLLTKQIF
IPEGISANYTFEYFNNCQFALKIECCAIVFILWLRMFIFLIRTQKFGLLVKVIILFTKDL
LYFMVILITVTVAFGLINYILFQNSLELYKSIDKSIFNLFAAAFGAFDFNNQTGIQSAIL
IVFLVVVNVILLNLLIAILNTRYEKTMQQSEMEYSLVVYNDYINSRFNPIYMSMISLPPP
FNILNFIFGIISFITKSRIWNKIALKIGYTLVIFLPCILLYIALSLVLIPFSYLYFIHQV
SMYSFSDNMMYARKKNKCFKITLYLFRLLTWITLGIPYLLVVFFSNDLPLFCKSAFAHNN
NKYNFTKNPVLDLRVIKYVSLYSNYLNLAKKDVFNYLEFRSSLEQKKEVKYKKSYFQRFA
QPSIKSNSQPLQQIRKGFQNNVKHNFKSETIFEKNFNDAVKKFGDSKVKQEVENIQLNNL
LKAIKYSAIFFKKSKSTSFNLSKLLYIVKKKEINLNLLQLNTDNFFLNRSFSSQPNINVN
NLN