Identifiers and Description

Gene Model Identifier

TTHERM_00127000

Standard Name

TMLH1 (Tetrahymena homolog of budding yeast MLH1)

Aliases

PreTt09363 | 9.m00384 | 3699.m00093

Description

TMLH1 DNA mismatch repair protein putative; DNA mismatch repair protein- C-terminal domain containing protein

Genome Browser (Macronucleus)

Full Screen View


Genome Browser (Micronucleus)

Full Screen View

Gene Ontology Annotations

Molecular Function

Biological Process

  • obsolete protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine (IEA) | GO:0050743
  • photosynthetic electron transport in photosystem II (IEA) | GO:0009772

Domains

  • ( PF01119 ) DNA mismatch repair protein, C-terminal
  • ( PF02518 ) ATPase, histidine kinase-, DNA gyrase
  • ( TIGR00585 ) DNA mismatch repair protein MutL

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_09117.1 9.997093137033517e-262
Description: DNA mismatch repair protein domain-containing protein (747 aa)
SGD YMR167W 8.999119107228014e-72
Description: MLH1 Protein required for mismatch repair in mitosis and meiosis as well as crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; human homolog is associated with hereditary non-polyposis colon cancer
DictyBase DDB_G0287393 9.999565105288807e-71
Description: mlh1 on chromosome: 5 position 247623 to 250277
Oxytricha Contig14864.0.g42 6.9991332754409754e-68
Description: DNA mismatch repair protein, C-terminal domain
WormBase WBGene00003373 9.004195835458823e-61
Description: locus:mlh-1 status:Confirmed UniProt:Q9XU10 protein_id:CAB07283.2
Stentor Coeruleus SteCoe_23547 2.3802664086944007e-26
Description: None

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:23935123: Lukaszewicz A, Howard-Till RA, Loidl J (2013) Mus81 nuclease and Sgs1 helicase are essential for meiotic recombination in a protist lacking a synaptonemal complex. Nucleic acids research 41(20):9296-309

Sequences 

>TTHERM_00127000(coding)
ATGAATCATTCCTAACCCTTAGAAAATACTGGTCCTCAGATCAAGAAGCTCCCATAAGAG
CTTATCGATAAGATTGCAGCTGGTGAAGTAGTACAACGTCCATCTGCAGCTGTTAAGGAG
CTTATTGAGAACTGTCTTGATGCTGGATCAAGTGAAATTTCAGTAGGGTTAGTATAAGGA
GGGTTAAAGTAGCTTATTGTAGAAGATAATGGTTCTGGAATTCACAAAGACGATTTTCCA
CTTCTCTGCGAAAGGTTTGCTACCTCTAAGATAAATGAGTTTAATGACCTTTAGAGTTTA
GTTTCATTTGGCTTTAGAGGAGAAGCGTTAGCCTCTATTTCTTTTGTCTCCAACTTGAAA
ATCACATCTCGAAAACCTAATTCTGACCTAGGATATAAAGCTAGTTTCAAAAACGGTGTT
ATGCTTGGTGAAGAGCCTGAAGCAGTGAACTGTACTGAAGGGACTACAGTAGATGTCTAG
GATTTATTTTTTAACTATGATGCAAGGAGAAAAAGTTTAAATGTTAACGAAGAAAAAAAA
AGAGTACTCAAATTGATCGGACAATTTGCTATGCATCATGCTAAATTGAGATTTAAATTT
AAAAGTGATAACCAAATTCAATTCTCATCTCACAGTGTGCTTGGCTCTACAGAATTGCAA
AGAAGAGAATAAATTATGTAGCAAATTACTAAGATTGCAGATAAAAGCTTTACTTCATGT
GAAAGTGAGTCGACAGAATATTAAGTTAAATTTAAAGGAACTTTTTCCAACATTGGAGCT
ACTAAAAAATACAAAGAAATCACTCTCTTTATAAATAATCGTTTGGTTGAATGTGAATCT
ATCAAAAAAGCAGTAGAACGCTCTTACCAGTCTTGTTATTAAAGTATTCATGAAGAAGAA
GGTGGATATTTTTGCTACTTGAGCTTAGAAATGAATCCAAAGAACTTGGATCCTAATGTT
CACCCAACAAAAAAAGAAGTCAAATTCTTATTTGAGTACGAAATAGCAAAAGAAATTGAA
TCATGGATTTTCGAAAATTTGAAAAATTGTGGAGTTATCAAACAACTTTCAGCAAATATT
TCATAAAGAACATCTTCATTTGAAACTTCAAATGTGAAAAGAAGTAGCTCAAGTCAATTA
TATTTTGGTTCTTAGAGCAATTTATCTAAGCAAAATTCTGATTACTATCAACCCACCAAG
CAAATTCGTGTAGATCCCAGAGATTAGAAAATTACTAGATTCTTTTCAGTAGAAAGCTCT
GAAGATGGAAATAACAATTCAAATCAAAAAAATTATCAAAGTATTAATTATATTGAAGAG
CAGAAAGAAGAACATCTAAACAGTCAAGATGATATTGCTGAAGAACCTGTTGATATGATT
AAAAAGAAAAAGATGCTCAATGAAGAAAGAAATTAAACTTCAATCAGTAATATAGGAAGC
TCTGACTAATTAGATGCTAATAATGCTCGTTCAAGTGTCATCGATAGGGCAAATTCTTAA
GTTAATGACCCACGTATTTAAGTATAATAATAGTTATTGTCTTTAAGGAATCAAGATATC
CATGATACAACAAGTTCTTTCTTTAAAAATCTTACGTATGTTGGCTGTATTTCTTCTAAT
CACTTTCTAGCTCAATTTAGAGATGATCTCTACCTTATAAACTCTATTCCATTATGTTAA
GAAATATTTAAATTTGAAATTCTGAGAAACTTTGGATAGATTAAGCCTGTAGAGCTAAAT
TAAGCAATAGGTTTGAAGGATATTTTAGAGTATTTTTTATTAAATTTTGATGAGATACCG
AATGAGAAAAAGGAGTTCCATCTGTCAAATATGGATACTTACATCGAGTAATTTGGCTTA
TTGAGTGACTTTTTAAGAGACTCCGTAGGCATAGTCATCAAAGATTAAAAGCTCTTGGCT
TTCCCTAATTTATTTAATTTATTTGAAAATGATAATAACTTTAAAGATATCTCATACATT
CTGTTGAGAATAATCACCAAAGTTAATTTTAGCGAAATACTCTAATCAGGTATGGGCTTA
GCAAACGAATTATCATTCTACTTTGCTTGGCAATTAGAAAAATCGTTTAAAAATTAATTG
TAAAGACAGCATTTCTAGGAAACGCAAAAGCAGAAATGGGACGATTTCTTTGAATAAAAA
ATGCTCCCAATGATTAAAAAAAAACTTTCACTCCCTAAATTAGATATTAGCGAGTTTACA
GTTAAGCTATTTAAGCAAGAAGATGCATACAAGATCTTCGAAAGATGTTGA


>TTHERM_00127000(gene)
ATGAATCATTCCTAACCCTTAGAAAATACTGGTCCTCAGATCAAGAAGCTCCCATAAGAG
CTTATCGATAAGATTGCAGCTGGTGAAGTAGTACAACGTCCATCTGCAGGTATTTGAATC
CGTCCTTTTCTATTTTTCAATATCCTGATGATAGTTTCTTTCAAATCAAAGCATCACTTC
TTTGATTAAATAATTATCATATATCATTAAGCAGATTATTAATATCAAGAAATAAATATG
GGTTTTTAAAATTAAATTTTGCATTCCATTTTTCCTACGCTAGAAATCTAATTAAAGAAT
TTTTATTGCTGAATATTTTGTAGAAGTTATGATGCATTTTATTTACCCAATAAACTGTTT
GCTCTCATCAGCTTAAATTTAGAGTAAAATTAAGCTGCTTGCTATTCCTGATTATTTTCT
TTAGTATAAATTAGATTTTCAGTAAATTTAGGAATATTGTTTGTTTAGTATTTTAACATA
CAATAAATAATAAGGGCAAATAAATATGTTAGTTAACAAATGAAAGGACATAAAGGAGTT
GATTAAATGAAAGGATAAAATTTTAATTGATCATTTTATTAAATTTTTTTGTTTATTTAT
AATTAATTATAGCTGTTAAGGAGCTTATTGAGAACTGTCTTGATGCTGGATCAAGTGAAA
TTTCAGTAGGGTTAGTATAAGGAGGGTTAAAGTAGCTTATTGTAGAAGATAATGGTTCTG
GAATTCACAAAGACGATTTTCCACTTCTCTGCGAAAGGTTTGCTACCTCTAAGATAAATG
AGTTTAATGACCTTTAGAGTTTAGTTTCATTTGGCTTTAGAGGAGAAGCGTTAGCCTCTA
TTTCTTTTGTCTCCAACTTGAAAATCACATCTCGAAAACCTAATTCTGACCTAGGATATA
AAGCTAGTTTCAAAAACGGTGTTATGCTTGGTGAAGAGCCTGAAGCAGTGAACTGTACTG
AAGGGACTACAGTAGATGTCTAGGATTTATTTTTTAACTATGATGCAAGGTAAATTCAAT
TATAAATTAAAAATATGTTGTTGAAATAACAATTATCGCGTTAAAGCCATTCATTCATTT
ATCATAAAATCAAAATACTAATATATATTTTGATAATTTTCAAGAAAAATTTATAGTTTA
GAAACAAAGGTGTTAAAATTTTGTCATTCAATCAATCAATTTTCATTAATTTGATTACTA
TTTAATGTTTATTTCTCTCTCATTAACATTCATTTTAATGGCAATTAATCATTCATAATT
CTCAAATAAATTCTTCTTAAAGCTACGAAAATATTTAATTCTAGTAAAAGTGTATTGAAA
AAGGCTTGAACATATAAAAATATTTTTAATTCCTTCAAAGATTAACAGAAAGTTAGCAAA
AATAATTTATAGTTTTATACTTTTAAGGTGTTTAATTAATTGAATCAACCATAGCAAAGC
AAAAATAACAGCCCAATTTAGATAGCTTTTTTATTTAAAAATGCAAACAATATTATACAG
TTTATAAATGCTGCTCTGTAGCTATTGAAGAGAAAGAGAGAGATTTATTTTTGGCTGTTA
TGAATTGAATGAAATTGATAATGATAATTGAGATTAGAAAGTAAGTATTATTAAATAAAA
TAGGGGGTCTACGAATATTCGAAAGAATTATAATCAATTGGCTTTACTTTTTTTTTCTTT
TTGATTTAGAAGGTGAAAGTAAATTTACAAAATATGTTAATAGAGATAAAAATTTTTGGT
ATTTCCTTCAGCTTACGTTAATTTATTTAATTTAAATGCAAATAAATTACTAAAACTTAA
TACCTTGCCATTTTTGGAAGTAAAGAAATAAATAAAAAAATATAATTTTGAAGAAATCCT
TTTTATCTTTTTAATTTTCCTAAATTTTATCTTCTAATTCAATAATTTTGAATGAATGAT
TTCTTTGCCACTAATAAAAATTAAGTTTTGAGATAGAAATAAAATAATTAAATTGATTTA
GATTATTATTAAATTAATGAATGCGCACAATTTTTTTTTATAAATGAATTAATATTTGAC
TCAATCAATCAACCTAAACTAAAAACTCTACCCAGTTGATTATTTTTTATATCTACTAAT
TATTAATTTAAATTTCTTGTTCGTTCACCCATAAAACAAACAAAAAAGTTTTTACTTTAA
ACCAAATATTTTAAAATATTGTCCACGTAATTAAATAACAAAGGGTTATTTTAATATTAA
TAATTATAAATATATTCATTGATTAATACACTCATAATAAATACCTTCTACTTTATAAAA
AATATAATTAATTAATTAATTAATTAAATAAATAAATTTCTCACTTTAACTTATAATTCT
ATTTTAAATAATTAGGAGAAAAAGTTTAAATGTTAACGAAGAAAAAAAAAGAGTACTCAA
ATTGATCGGACAATTTGCTATGCATCATGCTAAATTGAGATTTAAATTTAAAAGTGATAA
CCAAATTCAATTCTCATCTCACAGTGTGCTTGGCTCTACAGAATTGCAAGTAAACTTTCG
TAAACATTAAATACATTTTAATTAATTCTAATTAAATTCTAGAGAAGAGAATAAATTATG
TAGCAAATTACTAAGATTGCAGATAAAAGCTTTACTTCATGTGAAAGTGAGTCGACAGAA
TATTAAGTTAAATTTAAAGGAACTTTTTCCAACATTGGAGCTACTAAAAAATACAAAGAA
ATCACTCTCTTTATAAATAATCGTTTGGTTGAATGTGAATCTATCAAAAAAGCAGTAGAA
CGCTCTTACCAGTCTTGTTATTAAGTAAAACCTTTTTACCTAATTAACTAATGAGATTTA
ATCAACAATTTTAATTATCATTAGAACTGCTTTAAATTTAATTTTATATAATAATTACAT
AACAATAATAATAATATATATATAGAGTATTCATGAAGAAGAAGGTGGATATTTTTGCTA
CTTGAGCTTAGAAATGAATCCAAAGAACTTGGATCCTAATGTTCACCCAACAAAAAAAGA
AGTCAAATTCTTATTTGAGTACGAAATAGCAAAAGAAATTGAATCATGGATTTTCGAAAA
TTTGAAAAATTGTGGAGTTATCAAACAACTTTCAGCAAATATTTCATAAAGAACATCTTC
ATTTGAAACTTCAAATGTGAAAAGAAGTAGCTCAAGTCAATTATATTTTGGTTCTTAGAG
CAATTTATCTAAGCAAAATTCTGATTACTATCAACCCACCAAGCAAATTCGTGTAGATCC
CAGAGATTAGAAAATTACTAGATTCTTTTCAGTAGAAAGCTCTGAAGATGGAAATAACAA
TTCAAATCAAAAAAATTATCAAAGTATTAATTATATTGAAGAGCAGAAAGAAGAACATCT
AAACAGTCAAGATGATATTGCTGAAGAACCTGTTGATATGATTAAAAAGAAAAAGATGCT
CAATGAAGAAAGAAATTAAACTTCAATCAGTAATATAGGAAGCTCTGACTAATTAGATGC
TAATAATGCTCGTTCAAGTGTCATCGATAGGGCAAATTCTTAAGTTAATGACCCACGTAT
TTAAGTATAATAATAGTTATTGTCTTTAAGGAATCAAGATATCCATGATACAACAAGTTC
TTTCTTTAAAAATCTTACGTATGTTGGCTGTATTTCTTCTAATCACTTTCTAGCTCAATT
TAGAGATGATCTCTACCTTATAAACTCTATTCCATTATGGTAAATTCATCTTTAAATCAT
TCGCTCTTTCTTTTAAATTTTAATGGAAACAAAAAAATAAACCAAAATATTTATTTATCA
TTTTAGAAACATTTTTTTGATTTTAATAACCAAAATATTTATTTTAAAAAAAGTTAAGAA
ATATTTAAATTTGAAATTCTGAGAAACTTTGGATAGATTAAGCCTGTAGAGCTAAATTAA
GCAATAGGTTTGAAGGATATTTTAGAGTATTTTTTATTAAATTTTGATGAGATACCGAAT
GAGAAAAAGGAGTTCCATCTGTCAAATATGGATGTATGTTAGTTATTTGTTAATTTTATC
AATAAATAAAATATTTTGATTAAAATTAGACTTACATCGAGTAATTTGGCTTATTGAGTG
ACTTTTTAAGAGACTCCGTAGGCATAGTCATCAAAGATTAAAAGCTCTTGGCTTTCCCTA
ATTTATTTAATTTATTTGAAAATGATAATAACTTTAAAGATATCTCATACATTCTGTTGA
GAATAATCACCAAAGTAAATAAATAAATAAAAAGCTATTTGCTTATTTACAAACAATATA
TAATAAACTTTTTAAATTCAAAGGTTAATTTTAGCGAAATACTCTAATCAGGTATGGGCT
TAGCAAACGAATTATCATTCTACTTTGCTTGGCAATTAGAAAAATCGTTTAAAAATTAAT
TGTAAAGACAGCATTTCTAGGAAACGCAAAAGCAGAAATGGGACGATTTCTTTGAATAAA
AAATGCTCCCAATGATTAAAAAAAAACTTTCACTCCCTAAATTAGATATTAGCGAGTTTA
CAGTTAAGCTATTTAAGCAAGAAGATGCATACAAGATCTTCGAAAGATGTTGA


>TTHERM_00127000(protein)
MNHSQPLENTGPQIKKLPQELIDKIAAGEVVQRPSAAVKELIENCLDAGSSEISVGLVQG
GLKQLIVEDNGSGIHKDDFPLLCERFATSKINEFNDLQSLVSFGFRGEALASISFVSNLK
ITSRKPNSDLGYKASFKNGVMLGEEPEAVNCTEGTTVDVQDLFFNYDARRKSLNVNEEKK
RVLKLIGQFAMHHAKLRFKFKSDNQIQFSSHSVLGSTELQRREQIMQQITKIADKSFTSC
ESESTEYQVKFKGTFSNIGATKKYKEITLFINNRLVECESIKKAVERSYQSCYQSIHEEE
GGYFCYLSLEMNPKNLDPNVHPTKKEVKFLFEYEIAKEIESWIFENLKNCGVIKQLSANI
SQRTSSFETSNVKRSSSSQLYFGSQSNLSKQNSDYYQPTKQIRVDPRDQKITRFFSVESS
EDGNNNSNQKNYQSINYIEEQKEEHLNSQDDIAEEPVDMIKKKKMLNEERNQTSISNIGS
SDQLDANNARSSVIDRANSQVNDPRIQVQQQLLSLRNQDIHDTTSSFFKNLTYVGCISSN
HFLAQFRDDLYLINSIPLCQEIFKFEILRNFGQIKPVELNQAIGLKDILEYFLLNFDEIP
NEKKEFHLSNMDTYIEQFGLLSDFLRDSVGIVIKDQKLLAFPNLFNLFENDNNFKDISYI
LLRIITKVNFSEILQSGMGLANELSFYFAWQLEKSFKNQLQRQHFQETQKQKWDDFFEQK
MLPMIKKKLSLPKLDISEFTVKLFKQEDAYKIFERC