Identifiers and Description

Gene Model Identifier

TTHERM_00189270

Standard Name

PAH1  (Phosphatidic Acid phosphoHydrolase )

Aliases

PreTt08677 | 15.m00388 | 3697.m00100

Description

LNS2 (lipin/Ned1/SMP2) protein; Mg2+-dependent phosphatidate (PA) phosphatase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF03767 ) HAD superfamily (subfamily IIIB) phosphatase
• ( PF04571 ) lipin, N-terminal conserved region
• ( PF08235 ) LNS2 (Lipin/Ned1/Smp2)
• ( TIGR03333 ) 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_06282.1	9.997093137033517e-262
	Description: lipin (872 aa)
Oxytricha	Contig18266.0.g54	1.0001267035975107e-72
	Description: LNS2 (Lipin/Ned1/Smp2)
DictyBase	DDB_G0271730	4.99966753182923e-69
	Description: DDB_G0271730 on chromosome: 2 position 868232 to 872209
WormBase	WBGene00010425	8.996727126836489e-63
	Description: locus:lpin-1 status:Confirmed UniProt:Q9XXT5 protein_id:CAA16154.2
SGD	YMR165C	3.000235161122315e-61
	Description: PAH1 Mg<sup>2+</sup>-dependent phosphatidate (PA) phosphatase, catalyzes the dephosphorylation of PA to yield diacylglycerol, responsible for de novo lipid synthesis and formation of lipid droplets; homologous to mammalian lipin 1
Stentor Coeruleus	SteCoe_8579	1.6458114310822737e-38
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00189270(coding)
ATGAGTGTTTTAAAAAAACTATAAGAAGTTTTTGATATAAATGAATCTACTTTGAGTGGT
TGTGTTGATATTATTTGCATAGAGTAGCCTGATAAAACTCTTAAGTCCTCTTCTTTCCAT
GTTAGATTTGGAAAGTTCAAAGTACTTAAAAGCAATGAAAAGATAGTTACTATCAAGATT
AATGATATAATTCAAAAAGTTACTATGAAGATGGATTCAACAGGAGAAGCTTATTTTGAA
GATATTAGAGATGAAAGCGCTTTGGAAAAAATATTTAATGCAGGTCTTTCATCAGATGAT
GCGTTTTCAGATTATGAAATACCAAATATGTAATCAGATGATGAAGGTGCATTTGACAAA
GAAAAGATAAATGAACAGATAAGCAAAAATTAGTATAGGTTTGATGATTTAGTTTCTCCA
TACAAAGACGTAAAAGAAAAAGAAAAAGAAGGAAAGTAAGCAAATAACATAAATGTCAGT
AATTAAGGATAGCAAACTAAGGAAAAGGAGGTATCAGCTCTACCTTAAAATTAAAATTAA
CCTGAATAGAAGAAAGGAGGATTTTGGCATTCTATTTTTGGTGGTAGAAAGAAATAAGAA
GATAGTATAAGTAATCAGACTAGTAGAAAAAATTCAGAAAATCCTACTTTAGAAGAGCTA
CAAAAAATTACTTAAGAGTAGGTTAAAGAATAGAATATAAGTGAAGTAAAATAAGAAGGA
TCTACTTAACTGCCAAGTTCTTCATTTAATTCTAATGGTGTAGCTTCAAGTGATATCGAA
AGCGAAGTTGATAAATTTGTTATCAATGACGAAATTTAGGAGCGCAGTAAAAATTAATAA
AAGAATCAAAATATAAATAATAGCAAATCTTAAGTCAGTAATTCTAATAGCTTGTAATTC
AAAGAAGATAAATATAAAATGAGTGAAGTAGTAGAAAATTTAGAAAAAAAGAAGCCTTCT
CCTTCTATGGAAAAGAAATCATCTACTGAAGGAGTAAGTGAAACCTTAGAGAGAAAAGAA
AGTTAAAAATAATTAAACACTAATTAGAGCCAGACAAATACCTAAAATTCAGAAAAGGAT
AAAAAGAAAGATGGAAAAGATTAAAATAAGATTGAGATGAAAGATCTCATTGATTAAAAT
AAAGATCTTAAAGATTTAATATCTTCAAAAAAGCAAGATAAATAGTAAGTAGCTTAATAG
GAGGCTGGTAAAATCTAAGAAGTTAAAGAAGAAGGAAATGAAGAGGAAGAAGATGAAGAA
GAAGAGGATGAAGATGAAATGGAAATAGGTTTATCACTTTGCAATAACGTTTAGCAGAAA
AAAGGTGAAAATAAATCATTAGATTAGTTATTTGAAGATTATAAAGTTACTTATGAACAA
TTCAGTTAAGATCCAGTCAAGATTTTAAATGATAAAAATCTTTTGCTTAAAATTGGATAT
CATTTATATCCCTTAGAAATTGCTTCCACAATTCTTATTTGTCGTTTGGCATTCAAATAA
GAAATCCCTGATAATGTTCTACAAAATATGATTAAGCAATAAAAAAAGAAATCATCTTCT
GGTTTCTTAGATTTCTTTTTCCGCCGTAACAAAAATGAAAGCACTCCACAATCTGATGTA
CTTGGCTAAATTATGCCTATGCTTGATAAAGATTGGACTCATGAAGGCGTCATTAGTTTA
TATTAAAATATAGTCAAAAATGGCTATTAAATTTTATATTTAACTGCAAGAGCTATTGGG
CAATCGGAGTAAACCAGAAAATTTATCTATAATGTGAAGCAAGAAAACGTCAATCTCCCT
TTAGGACCTGTAATAATGTCATCTGATAGATTACTTAAATCTTTTAAAAGAGAAGTTATA
GACAGAAAACCTGAGGTTTTTAAAATTGCTGTTTTAAGAGAAATTTAGTCTTTGTTCCCT
AATAAAAACGTCTATTATGCAGGATTTGGAAATAGAGAAACAGATGCTGTAGCCTACAGA
GCAGTTTAAGTTAGTATTTAAAAAATTTACATTATTAATCCAGCTTCAGAGCTTCACTAA
ATAAATAACACTTTCAAAAAAAGCTATTTATAGTTAAATGATATGGTTGATTAAGTATTT
CCTCCCATCAAGCAGGAAGAAGATTAAATTTAAGAAGAATATAATTCATTTAATTTCTGG
AAAATAAAACCACCAGCTGTTGAAGATATTAACTAACTATTAAGCGAATGA

>TTHERM_00189270(gene)
ATGAGTGTTTTAAAAAAACTATAAGAAGTTTTTGATATAAATGAAGTAATTTATTTTTAT
TCTCCACTTGCAAGTTCTGCCTTCTTTTTATATACTCAAATTTTATTTTTATTACCTAAA
GTCTACTTTGAGTGGTTGTGTTGATATTATTTGCATAGAGTAGCCTGATAAAACTCTTAA
GTCCTCTTCTTTCCATGTTAGATTTGGAAAGTTCAAAGTACTTAAAAGCAATGAAAAGAT
AGTTACTATCAAGATTAATGATATAATTCAAAAAGTTACTATGAAGATGGATTCAACAGG
AGAAGCTTATTTTGAAGATATTGTAATCAATTTTCATATCTATTTTTTAAATTAAAATTA
GCAAAACTCATTTAATATTACTTTATTCTAAAAAAGAGAGATGAAAGCGCTTTGGAAAAA
ATATTTAATGCAGGTCTTTCATCAGATGATGCGTTTTCAGATTATGAAAGTATTTCCAAA
ATGTATATCATTTAAAGTAACAAATATACATAATTATATAGTACCAAATATGTAATCAGA
TGATGAAGGTGCATTTGACAAAGAAAAGATAAATGAACAGATAAGCAGTAAATAAAATTC
AATTTATAATGAGTTTATAGCATTATAAACGTTAATAAAAGAAAATTAGTATAGGTTTGA
TGATTTAGTTTCTCCATACAAAGACGTAAAAGAAAAAGAAAAAGAAGGAAAGTAAGCAAA
TAACATAAATGTCAGTAATTAAGGATAGCAAACTAAGGAAAAGGAGGTATCAGCTCTACC
TTAAAATTAAAATTAACCTGAATAGAAGAAAGGAGGATTTTGGCATTCTATTTTTGGTGG
TAGAAAGAAATAAGAAGATAGTATAAGTAATCAGACTAGTAGAAAAAATTCAGAAAATCC
TACTTTAGAAGAGCTACAAAAAATTACTTAAGAGTAGGTTAAAGAATAGAATATAAGTGA
AGTAAAATAAGAAGGATCTACTTAACTGCCAAGTTCTTCATTTAATTCTAATGGTGTAGC
TTCAAGTGATATCGAAAGCGAAGTTGATAAATTTGTTATCAATGACGAAATTTAGGAGCG
CAGTAAAAATTAATAAAAGAATCAAAATATAAATAATAGCAAATCTTAAGTCAGTAATTC
TAATAGCTTGTAATTCAAAGAAGATAAATATAAAATGAGTGAAGTAGTAGAAAATTTAGA
AAAAAAGAAGCCTTCTCCTTCTATGGAAAAGAAATCATCTACTGAAGGAGTAAGTGAAAC
CTTAGAGAGAAAAGAAAGTTAAAAATAATTAAACACTAATTAGAGCCAGACAAATACCTA
AAATTCAGAAAGTAAATTATAATATAATAACTACCCACCATTAAAACTATTCAAAAGCAA
TAATTGAAACTGTTTGAAATTTTTTTCATATTTAAAAAAAGAGGATAAAAAGAAAGATGG
AAAAGATTAAAATAAGATTGAGATGAAAGATCTCATTGATTAAAATAAAGATCTTAAAGA
TTTAATATCTTCAAAAAAGCAAGATAAATAGTAAGTAGCTTAATAGGAGGCTGGTAAAAT
CTAAGAAGTTAAAGAAGAAGGAAATGAAGAGGAAGAAGATGAAGAAGAAGAGGATGAAGA
TGAAATGGAAATAGGTTTATCACTTTGCAATAACGTTTAGCAGAAAAAAGGTGAAAATAA
ATCATTAGATTAGTTATTTGAAGATTATAAAGTTACTTATGAACAATTCAGTTAAGATCC
AGTCAAGGTTAAAATTTATTTAAAGTCTTTAAATTAACTTAGGTAATTTGTATCTAAAAA
TAGATTTTAAATGATAAAAATCTTTTGCTTAAAATTGGATATCATTTATATCCCTTAGAA
ATTGCTTCCACAATTCTTATTTGTCGTTTGGCATTCAAATAAGAAATCCCTGATAATGTT
CTACAAAATATGATTAAGCAATAAAAAAAGAAATCATCTTCTGGTTTCTTAGATTTCTTT
TTCCGCCGTAACAAAAATGAAAGCACTCCACAGTAGAAGCCAGTAGAAGTAGAGCATACT
TAGCAGAAAGATAAAACCCTCAAAAAAGATATTTCTAATTTACAGTTAAATTCAGGAGAC
AAAAATGATTAGTAAGTATCTAGCCCAATACAATCCCCAAAAGTGCTGATAATCTTGATA
TAAATAAAGCTAGAAAAAATAGTGATGAACTCTCAGTTGTGAGTGATTCTAACTCAGTAT
TTGGAAAATAAAAAATTAGAAAAACATTTAGACCAAAATCAGATATTCTCAAATCTTTTA
ATTTAAAACCTGGTGCTAACAAAATTAGTTTCACAGTAGTAACTAAATTGCTAGGAGAAT
AGACATTGGAAGGATATATTTATTTATGGTAGAGCAATGTCTAAATTGTAATTTCAGACA
TAGATGGAACAATCACCAAGTAAATTTTATATTATTTCAATAATATTAATAATAATAAAA
AATTATTATAATAAAGATCTGATGTACTTGGCTAAATTATGCCTATGCTTGATAAAGATT
GGACTCATGAAGGCGTCATTAGTTTATATTAAAATATAGTCAAAAATGGCTATTAAATTT
TATATTTAACTGCAAGAGCTATTGGGCAAGTAATTAATTAAATTAATTGATCTAATCTAT
ATTTTAAAATATTATAATTAAAGTCGGAGTAAACCAGAAAATTTATCTATAATGTGAAGC
AAGAAAACGTCAATCTCCCTTTAGGACCTGTAATAATGTCATCTGATAGATTACTTAAAT
CTTTTAAAAGAGAAGTTATAGACAGAAAACCTGAGGTTTTTAAAATTGCTGTTTTAAGAG
AAATTTAGTCTTTGTTCCCTAATAAAAACGTCTATTATGCAGGATTTGGAAATAGAGAAA
CAGTAGAATCAATTAATTTAATTTATAAAGTTAAATATTTTTTATATTAAAATAAAGGAT
GCTGTAGCCTACAGAGCAGTTTAAGTTAGTATTTAAAAAATTTACATTATTAATCCAGCT
TCAGAGCTTCACTAAATAAATAACACTTTCAAAAAAAGGTAAGGATTTAAAAAGTTTAAT
ATAAATTTATTTTATTATTTTATTTATTTAAATAAATAAATAAATTTTTTATAATTGAAA
AGCTATTTATAGTTAAATGATATGGTTGATTAAGTATTTCCTCCCATCAAGCAGGAAGAA
GATTAAATTTAAGAAGAATATAATTCATTTAATTTCTGGAAAATAAAACCACCAGCTGTT
GAAGATATTAACTAACTATTAAGCGAATGA

>TTHERM_00189270(protein)
MSVLKKLQEVFDINESTLSGCVDIICIEQPDKTLKSSSFHVRFGKFKVLKSNEKIVTIKI
NDIIQKVTMKMDSTGEAYFEDIRDESALEKIFNAGLSSDDAFSDYEIPNMQSDDEGAFDK
EKINEQISKNQYRFDDLVSPYKDVKEKEKEGKQANNINVSNQGQQTKEKEVSALPQNQNQ
PEQKKGGFWHSIFGGRKKQEDSISNQTSRKNSENPTLEELQKITQEQVKEQNISEVKQEG
STQLPSSSFNSNGVASSDIESEVDKFVINDEIQERSKNQQKNQNINNSKSQVSNSNSLQF
KEDKYKMSEVVENLEKKKPSPSMEKKSSTEGVSETLERKESQKQLNTNQSQTNTQNSEKD
KKKDGKDQNKIEMKDLIDQNKDLKDLISSKKQDKQQVAQQEAGKIQEVKEEGNEEEEDEE
EEDEDEMEIGLSLCNNVQQKKGENKSLDQLFEDYKVTYEQFSQDPVKILNDKNLLLKIGY
HLYPLEIASTILICRLAFKQEIPDNVLQNMIKQQKKKSSSGFLDFFFRRNKNESTPQSDV
LGQIMPMLDKDWTHEGVISLYQNIVKNGYQILYLTARAIGQSEQTRKFIYNVKQENVNLP
LGPVIMSSDRLLKSFKREVIDRKPEVFKIAVLREIQSLFPNKNVYYAGFGNRETDAVAYR
AVQVSIQKIYIINPASELHQINNTFKKSYLQLNDMVDQVFPPIKQEEDQIQEEYNSFNFW
KIKPPAVEDINQLLSE