Identifiers and Description

Gene Model Identifier

TTHERM_00256950

Standard Name

TXR1 (Trithorax-related protein 1)

Aliases

PreTt25381 | 22.m00326

Description

TXR1 SET domain protein; SET domain containing protein; homolog to Arabidopsis ATXR5 and ATXR6.

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• protein binding (IEA) | GO:0005515
• zinc ion binding (IEA) | GO:0008270

Biological Process

• regulation of DNA-templated transcription (IEA) | GO:0006355

Domains

• ( PF00097 ) zinc finger, C3HC4 type (RING
• ( PF00130 ) Phorbol esters/diacylglycerol binding domain (C1
• ( PF00412 ) LIM domain
• ( PF00628 ) PHD-finger
• ( PF00856 ) SET domain
• ( PF06827 ) Zinc finger found in FPG
• ( PF07649 ) C1-like domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_10415.1	9.997093137033517e-262
	Description: SET domain-containing protein (642 aa)
Oxytricha	Contig14985.0.g5	1.000159011384939e-43
	Description: SET domain
DictyBase	DDB_G0282427	0.00000000009998509410508463
	Description: DDB_G0282427 on chromosome: 3 position 5755702 to 5758268
WormBase	WBGene00002637	0.000000009996807949091551
	Description: locus:let-418 Protein let-418 status:Confirmed UniProt:G5EBZ4 protein_id:CCD62685.1
SGD	YJL168C	0.00000006998394348458725
	Description: SET2 Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p
Stentor Coeruleus	SteCoe_1744	0.0024787521766663585
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:24382802: Zhang C, Gao S, Molascon AJ, Liu Y, Andrews PC (2014) Quantitative proteomics reveals histone modifications in crosstalk with H3 lysine 27 methylation. Molecular & cellular proteomics : MCP 13(3):749-59
2. Ref:23150054: Zhang C, Molascon AJ, Gao S, Liu Y, Andrews PC (2013) Quantitative proteomics reveals that the specific methyltransferases Txr1p and Ezl2p differentially affect the mono-, di- and trimethylation states of histone H3 lysine 27 (H3K27). Molecular & cellular proteomics : MCP 12(6):1678-88
3. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences

>TTHERM_00256950(coding)
ATGAATGATTATGAATCTTAATTAAAATAATTGATTATAAATCACTTTATAAGGATAAAG
CAATAGATAATTTATCAATAAAAAAATAAATCCAAAAAAATTAAATTAAGAGTCTTATTA
TTTAAAAAAAAGAGCAAATAACGAAAAAGTTATTTCGAAAAGAGAATAATAATTCTACGA
TAATACTAATAACCAAGTAAGAGTAAATTATAAATGGGACGTAAGAGAAGAGCTATGAAG
GCTAAATTGGATTAATTTTTGGAATACATTCATTCTTCGGAGGAAAAGATGACCTAGGAG
TAATATCTTTAACTCGTAAGAGAAAAGGTGAAGTAATTTTCAAAAAAAGATCTTAAGTAG
ATTCAAACAAATTACATTCTGGAAAAGATCTGTGAAGTATGTAATGACTATCATCACGAT
GAATAACTACTCCTCTGCGATTACTGTGATGATGCTTATCATTCTTTTTGCCTCAACCCA
CCTCTTAAGGAAATTCCTGATGAAGAAGAAGATTGGTTTTGTCCAGTCTGCGTTGAATAA
AAATATTAAATGGAAAAAGAGAAAAGAAGCAGTGGAGGAAGGAGATCTAATTCAAAAGTA
CAAAAACTGCTCGAGTAGTTTAATTTTAAAAATTAAAGAGATGTTGCTTAAAAGATACAG
ATTTGTGGAAAATGTGATGATATGATTCTCTACATGGAGAACGAAGGTGTGATTGAAGAA
AGCGAGAAATGTATCAAATGTAATAAAATGTATCACAAAGAGTGCTTCAGTAAAAAGAAA
GAATCTATTTTATGCAATTCCTGTCAAACGCTTATCAAAAAATAAATCCCTACTGATTAG
AAACTTATCGAGGATTACTTCATTAGAGGATAGCAAGAATCTTTGGGTAATAAACCCTAC
GAATAGGATGATAAGAAGTCAGATAAAAAAAATAAAGCTACTCAGGATTCTAAGAAGATG
ATTAATGAAAATAAAAAGGAGAAGCAGGATGATGAAAGTGATGATGAGATACTTGATGTT
GATGCTCTTAAAGAAATGGAAAATATGAGATAAACTCGTGGAAGAAGAGCTAAATTGTTG
TAAGAAAAAGAATAAAAAGAATAAAAGTAAAGTTAAAAAACAGATAAATCTACTAAAGTT
GAATAACAAACTCGCATCACTAGATAAAGAACTCAAGAAAAAATAGATAAATTAAATGAT
TAATATATTAACGACTCAAATAAAACAGTTAACTCTGTTTTGGCTAAAAAAAGAAAGAAA
AATGATTCTACTGAATTTATAAGTAATAAAACTTAAATTAACGATGACTCTTTGACTCAA
CCACTGGCTATTAACTAAAAATCTAGCAGCAGCAGTAGTTATTATAATGACGACTGCGAG
TCTAATATGTCTACAACTTATTCATCAACAAGCAATGAAACATAAGCTAAAAACACTACT
GCACCTATAAATTCAAAAGGAGGAGTTAAATTCCTACTTCCAGTTCCAAGCTCTAATCCA
ATTGTTAATTTAGAATGCAAGCAATCTTTAATCTATGCTTTGAAAGCTAAAAACATCTAA
TTCTGCGACGATTTGTGCTACACTTAACAATGCCCTAAATAAAGCAATAATGCTAATTTA
GAACCAAATTTGTAAGTAATTGATCTTGCAAATAGCATTATATTCTAAAAATTCAAAGAA
ATGAGCAGATAGGGGATTTATGCTCCTGTTGTAGTAGAAGAAGATAAGATACAAGGATTT
ATAGTAAGAGCTATGGATGATATAAAGGCAAAGACTTTAATTTGCGAATATGTTGGTGAG
GTCGATTATGCTAGAAACCACATCTTCAACAAAAACGACTCTATTATGGATCTTTTGAGA
ACAGCTAGATCAAAAACATCATTAGTAATTGTTCCTGATAAAAAAGGTAACCTTGCTAGA
TTCTTATCAGGAATTAATAATACTTCTAAAAAATCTATGGCTAAACAGAATGTCCACAGT
GTTAGATTCAACATTAATGGAGAATCAAGAGTAATTTTATATGCCAAAAGAAACATAAAA
AAAGGAGAACTTCTATATTATGACTACAATGCAGGAGGATTTGGAGAGTATCCAACATAA
AATTTTGTATGA

>TTHERM_00256950(gene)
ATGAATGATTATGAATCTTAATTAAAATAATTGATTATAAATCACTTTATAAGGATAAAG
CAATAGATAATTTATCAATAAAAAAATAAATCCAAAAAAATTAAATTAAGAGTCTTATTA
TTTAAAAAAAAGAGCAAATAACGAAAAAGTTATTTCGAAAAGAGAATAATAATTCTACGA
TAATACTAATAACCAAGTAAGAGTAAATTATAAATGGGACGTAAGAGAAGAGCTATGAAG
GCTAAATTGGATTAATTTTTGGAATACATTCATTCTTCGGAGGAAAAGATGACCTAGGAG
TAATATCTTTAACTCGTAAGAGAAAAGGTGAAGTAATTTTCAAAAAAAGATCTTAAGTAG
ATTCAAACAAATTACATTCTGGAAAAGATCTGTGAAGTATGTAATGACTATCATCACGAT
GAATAACTACTCCTCTGCGATTACTGTGATGATGCTTATCATTCTTTTTGCCTCGTAAGC
TCAAATAAATATTTCAATGCAAACTTTATCTCTCACTCTCTCTCATACATAAGTTATTTA
TATTTATTTAGTTTTCTTAATAATGTGAGGAAATAATCAAAAACTTTACTTTAGAAGTTA
AAATGATATAAAAAACACAAATATTTATGGATTAAAACACGATTTAATTCTCGTTTCTTA
TTGAAAAACTGAGTGAAGTGTTGGATTTTCGGAACTATGTAATAGTAAAAAGTATTTGGA
AATGTTATGGATAAAGAGAAACGATTTATAATATTTTGTTTGTAATTTATTTTAAAATAT
CGATTCATGATGTATAAAGCAAATCTTATGATGTTTAAATGAGAGAGAGAGTAGAAGTAG
ATAAGCAGCTTAAATTACTCAAAATCTTTTGATTTATAAACTAATAAATTTTATTTTAAA
TTTAGAACCCACCTCTTAAGGAAATTCCTGATGAAGAAGAAGATTGGTTTTGTCCAGTCT
GCGTTGAATAAAAATATTAAATGGAAAAAGAGAAAAGAAGCAGTGGAGGAAGGAGATCTA
ATTCAAAAGTACAAAAACTGCTCGAGTAGTTTAATTTTAAAAATTAAAGAGATGTTGCTT
AAAAGATACAGGTAAATTAACAAACAAATAAACTGTTTATTACATTTGAAGAGCCCTTCA
TTAGTCTATTAAAGCATGCTTCACTAAACAATTTTAAAGCGCTGTATCTTAAAATCAAGT
TTGCTCAAAATAATTCGTCTTTAATAAAAAAAATAATATTAACATGTAATGGAAATAAAT
AAAGAAAGATTTAATTTCTTTAGAATGATAAATTAAATGAATGAATGATTAATAAATAGA
TAAATAAATTAATAAATTTATATTACTTAAAGATTTTAAATCAATTTTTTAGAATAAAAA
AGCAAAAGAAGAAAATAAATTACAATGAATAACTCAAAAATTTAATTTTATCAATATTAT
TTTTCTTTCTCAAAATCTATCTAGAACTTTTATCATTGCTAAAAAGCTGAATTTCTACTA
ATAAATTAAATATACATACAAAACCATATTTTATAGAAGAGCAGTTATAGGATCTTTTTA
GATTGTATACCAATAAAAATCATTCTTTCATACATGGCAAATCTTTTTGATTTTGGACAG
ATAAAATGTTAGAAAATTATTTTATCAAGATTAATTATAGTTTTTACAGATAAATTTATA
AATTTCGCTTTCTATTTTAAATTTTTTTTATTTGAGCACAAAATCAACTAAAAAGATAAC
TCTAAATGCCTTTAAAAACTAAAAATTTTCTTATTCGATAAGTAGAATTAAATGTATATT
AAAATTATTATTATGAAAAAAAAAGATTTGTGGAAAATGTGATGATATGATTCTCTACAT
GGAGAACGAAGGTGTGATTGAAGAAAGCGAGAAATGTATCAAATGTAATAAAATGTATCA
CAAAGAGTGCTTCAGTAAAAAGAAAGAATCTATTTTATGCAATTCCTGTCAAACGCTTAT
CAAAAGTAATAAATTTAGTTTATTTAAAGACCTATCTATCTATAATTTTTTTTTCACTCA
AATTTCTTACACTTTAAACAATAAAAATTGAATGGAAGATAATAAATTACTTATAAAAAT
CATGTCTGATGAGAAAATAAAAACAATTCCTACTTCAAACACTGTCTTTGTTTTCTTTTA
CTTTACTAAAATTTTTATATTTCCTTCTTTTTCTACCCAAATTTAAAATTTTGTTTTTTA
TCTTAATCAAATTGAGCTTACATTTTTAATTAATTAAGACTAACAAACAAAAAGTAAAGG
AAACTAATCCTTTTGTATTTTTTTATTAAAGACACTCCATGTCTGAAGAACTCATTATAC
CATCAAATATTTATTGCTTCAACCATTCATTTTTATTTATAAATATTAAGATGGAAATTT
AAGAATGTTAAATTGTATTTTTGATTTCTTATAACTAAAATATCATTTAATTTATAAAGA
ATAAATCCCTACTGATTAGAAACTTATCGAGGATTACTTCATTAGAGGATAGCAAGAATC
TTTGGGTAATAAACCCTACGAATAGGATGATAAGAAGTCAGATAAAAAAAATAAAGCTAC
TCAGGATTCTAAGAAGATGATTAATGAAAATAAAAAGGAGAAGCAGGATGATGAAAGTGA
TGATGAGATACTTGATGTTGATGCTCTTAAAGAAATGGAAAATATGAGATAAACTCGTGG
AAGAAGAGCTAAATTGTTGTAAGAAAAAGAATAAAAAGAATAAAAGTAAAGTTAAAAAAC
AGATAAATCTACTAAAGTTGAATAACAAACTCGCATCACTAGATAAAGAACTCAAGAAAA
AATAGATAAATTAAATGATTAATATATTAACGACTCAAATAAAACAGTTAACTCTGTTTT
GGCTAAAAAAAGAAAGAAAAATGATTCTACTGAATTTATAAGTAATAAAACTTAAATTAA
CGATGACTCTTTGACTCAACCACTGGCTATTAACTAAAAATCTAGCAGCAGCAGTAGTTA
TTATAATGACGACTGCGAGTCTAATATGTCTACAACTTATTCATCAACAAGCAATGAAAC
ATAAGCTAAAAACACTACTGCACCTATAAATTCAAAAGGAGGAGTTAAATTCCTACTTCC
AGTTCCAAGCTCTAATCCAATTGTTAATTTAGAATGCAAGCAATCTTTAATCTATGCTTT
GAAAGCTAAAAACATCTAATTCTGCGACGATTTGTGCTACACTTAACAATGCCCTAAATA
AAGCAATAATGCTAATTTAGAACCAAATTTGTAAGTAATTGATCTTGCAAATAGCATTAT
ATTCTAAAAATTCAAAGAAATGAGCAGATAGGGGATTTATGCTCCTGTTGTAGTAGAAGA
AGATAAGATACAAGGATTTATAGTAAGAGCTATGGATGATATAAAGGCAAAGACTTTAAT
TTGCGAATATGTTGGTGAGGTCGATTATGCTAGAAACCACATCTTCAACAAAAACGACTC
TATTATGGATCTTTTGAGAACAGCTAGATCAAAAACATCATTAGTAATTGTTCCTGATAA
AAAAGGTAACCTTGCTAGATTCTTATCAGGAATTAATAATACTTCTAAAAAATCTATGGC
TAAACAGAATGTCCACAGTGTTAGATTCAACATTAATGGAGAATCAAGAGTAATTTTATA
TGCCAAAAGAAACATAAAAAAAGGAGAACTTCTATATTATGACTACAATGCAGGAGGATT
TGGAGAGTATCCAACATAAAATTTTGTATGA

>TTHERM_00256950(protein)
MNDYESQLKQLIINHFIRIKQQIIYQQKNKSKKIKLRVLLFKKKSKQRKSYFEKRIIILR
QYQQPSKSKLQMGRKRRAMKAKLDQFLEYIHSSEEKMTQEQYLQLVREKVKQFSKKDLKQ
IQTNYILEKICEVCNDYHHDEQLLLCDYCDDAYHSFCLNPPLKEIPDEEEDWFCPVCVEQ
KYQMEKEKRSSGGRRSNSKVQKLLEQFNFKNQRDVAQKIQICGKCDDMILYMENEGVIEE
SEKCIKCNKMYHKECFSKKKESILCNSCQTLIKKQIPTDQKLIEDYFIRGQQESLGNKPY
EQDDKKSDKKNKATQDSKKMINENKKEKQDDESDDEILDVDALKEMENMRQTRGRRAKLL
QEKEQKEQKQSQKTDKSTKVEQQTRITRQRTQEKIDKLNDQYINDSNKTVNSVLAKKRKK
NDSTEFISNKTQINDDSLTQPLAINQKSSSSSSYYNDDCESNMSTTYSSTSNETQAKNTT
APINSKGGVKFLLPVPSSNPIVNLECKQSLIYALKAKNIQFCDDLCYTQQCPKQSNNANL
EPNLQVIDLANSIIFQKFKEMSRQGIYAPVVVEEDKIQGFIVRAMDDIKAKTLICEYVGE
VDYARNHIFNKNDSIMDLLRTARSKTSLVIVPDKKGNLARFLSGINNTSKKSMAKQNVHS
VRFNINGESRVILYAKRNIKKGELLYYDYNAGGFGEYPTQNFV