Identifiers and Description

Gene Model Identifier

TTHERM_00294810

Standard Name

SMC3 (Structural Maintenance of Chromosomes 3)

Aliases

PreTt15591 | 27.m00251 | 3692.m00054

Description

SMC3 SMC family carboxy-terminal domain protein; SMC family; C-terminal domain containing protein; cohesin complex member

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Molecular Function

• anion exchanger activity (IDA) | GO:0015380 | Ref:23555314
• glutathionylspermidine synthase activity (IEA) | GO:0008885
• O-octanoyltransferase activity (IDA) | GO:0016414 | Ref:23555314

Biological Process

• amino acid catabolic process (IEA) | GO:0009063

Domains

• ( PF00005 ) ABC transporter, ATP-binding protein
• ( PF00038 ) Intermediate filament protein
• ( PF00515 ) tetratricopeptide repeat
• ( PF01576 ) Myosin tail
• ( PF02370 ) M protein repeat
• ( PF02463 ) RecF/RecN/SMC N terminal domain
• ( PF04702 ) Vicilin N terminal region
• ( PF07197 ) Protein of unknown function (DUF1409)
• ( PF07719 ) tetratricopeptide repeat
• ( PF08791 ) Viral envelope protein
• ( PF08946 ) Osmosensory transporter coiled coil
• ( TIGR00019 ) peptide chain release factor 1
• ( TIGR00253 ) conserved hypothetical protein TIGR00253
• ( TIGR00634 ) DNA repair protein RecN
• ( TIGR00864 ) polycystin cation channel protein
• ( TIGR01612 ) rhoptry protein
• ( TIGR02168 ) chromosome segregation protein SMC
• ( TIGR02169 ) chromosome segregation protein SMC
• ( TIGR03185 ) DNA sulfur modification protein DndD

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_08738.1	9.997093137033517e-262
	Description: SMC family domain-containing protein (1161 aa)
SGD	YJL074C	5.001636743996964e-56
	Description: SMC3 Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member
Oxytricha	Contig17078.0.g58	2.000704504372864e-47
	Description: RecF/RecN/SMC N terminal domain
WormBase	WBGene00004873	1.999534248571833e-46
	Description: locus:smc-3 status:Confirmed UniProt:Q9U2C1 protein_id:CAB57898.4
DictyBase	DDB_G0284499	1.9993007828132465e-27
	Description: smc2 on chromosome: 4 position 2051268 to 2054927
Stentor Coeruleus	SteCoe_15774	0.0000000001026187963170189
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:23555314: Howard-Till RA, Lukaszewicz A, Novatchkova M, Loidl J (2013) A single cohesin complex performs mitotic and meiotic functions in the protist tetrahymena. PLoS genetics 9(3):e1003418

Sequences

>TTHERM_00294810(coding)
ATGAGCATTAAATCAATATCTATAGAAAAATTTAAAAGTTACTCTAACTGCAAGATAGAA
GGACTCTCTGACAATATAAATATTCTGTATGGCAAGAATGGTTCTGGAAAATCTAATTTG
TTGGCTGCTTTATCATTTATAAGTTCTGATTAGTACGATAGAGCTGATCGAGCATAATTA
ATGAAAAATTATAAAGAAGGTGATCCTAAGGTCGAAATAGAGTTAGATAATTTAGTTAAA
ATAGATAAAAAAGATATGGAAGATGAGCCAAAAGCACAAAAAGTTATTCCTACCAGCGGT
GATAGTGTTTTATTAAGTAGAACTTTAGAGTAAAGGGAGAATGTTTATAGGGTAGATGAT
AGAGTTGTTAATTTAAATTAGTTTAATAATATTTTTGAGTGCTTTGGTCTTTCAAGAAAG
AATCCTTTTACAATAGTTGCATAAAATAGAATTTAAGAAATATCAAACATGAGTGATTCA
GAAATCTATAAGTTGTTACAGCAAGTAGCTGGAATAGAAGCTTTTATGAATAAATAAGAA
AAAGCAGAAGAGCTTTTCGAAAAAGCTTAGAGAGAAAAGGAAGGCATAGATTAATCCTTA
CAAGAAATAGAAGATAAAATAAGCTAGTTAAGTGGTGAGAAAGAATAGTATGCACAAAAT
TAAGAATAGGAAATTATTATATAAAGCTTGTAATCTATCTATTATGATAAATTGAAAGAA
GAGCTTTAAAAGAAGAAATTAGAATGCAACAAAGAAATCAATAATCAAAAATTGTAAGAA
GAGAAGTAAAAGCTTCAGGATTTATAAAATTAGAAAGAAGCTAAAAATGAAGAACTATTA
AGATTTAAAGAAAAATTGCAAAGATTAACAGTTATAGAAGAGCAAGTAAAATCAGATTAA
ATGAATCTTTAAAACAAAGTCAACAGTCTTGAGTAGAATATCTAAAAATTAAAATCAATA
AAAACTAACAAAGATGAAAAAGAAATTGAAGCAAGATTAAAAGAAGTTAATATTTAATGC
ACTAAATTATAAAAAGATCTTGATGAAGTCATTGATAAAATAACAAATGAAAAAGATGGG
ATTGACACCAAGCAGTAAGAATATGAGCAATTAGTCTTAAGAGAAAAGTTTAAAACTTAG
TAAGAAAAGCAAAGCTATTTTAATCAGAGAATCCAAGACATTAAACAAAGTATTAGTGAA
AAATCATAAACTTAACAGAATCTTAAAGAGAAAGTGAAAAAATCTGAATAAAGACTAAAC
TTAGTTAATTAAGAAATTGAAAAATTGTAAAATCAAATAAATAGTTTTTAAACTGAATCC
AATAAGGCACAAAAAACTATAAATGATAAAAAGAATTAAATCTAAAAATTGAGACAAGAG
TAGCTTGAAAAGAGAAAGACAATTAATGATAAAAAAATAGAGTTGGAAGATTTAAACAAC
TAAATAAAAAAGAGAGTTGATGATATACAAAAGTAGTTGAAATCAGGATTAATCCAAGCA
ATTGAGCAAATCGAGGAATCAATATAAAAAGAAGGTATTTAGGGATATAAAGGACTGCTT
ATAGATCATCTTTAATTTAATTCTGCACTTACTTATGCATATGATATTGCTCAAAAAGGA
AAATTATTTTCTTTGATAGTCGATAATCAAAATACTGCCTCTTTAATAATTGATATTGTT
AAGAAATTGAAGATTAAAACATCAAATTTAAATATTATTCCCCTAGATTGGGTTGAAGAT
GATATTGATGATGAAAAAGAAAACTAAATTGCAGGATTCGGATTTTAAAAGCTATTTGAT
ACTAGGTATGTTAAGGCAAAAGGAGATCATGCAGATGATATAAAAAGGTTAGCTAAGAAT
ATTTTTGAAAAATATGGTGTAATTAAAGAGTATGAACATGCCCTAGAGGTAGCATCTTAA
TTTAAAGTAAACTGCATTACAGAGAAGAGATAAATTGTTTATAGTGGAGGTTTTATTTCT
CATGTTGGTTTTTGTACTGTGGCTAAAGTAGATAAAATAACACTTTACAATGAATACAAA
AGCTTTAAAGCTAAGAAAGATGCTATTGCTAAAGAAATAGAGCAACTAGAGAAGTCTATG
AATGATATTTAATTGTAATAAAATGATATAAATTCAAATGTAAGCAAAGAATAAGCTAGC
TTAGCAAAATAGAGTAACACTATATTTATGAATCGTTAACTAATTAAATCATCTGAAGTA
GAGAAAAAAGTATTGACTGATGAGTTAAACGAAACAAATTAACTCCTATAGTCTTTTTCT
TAATAACTTAAAGATTTAGAATAAGAGAAAATAGGTTTAGAAAATACTAGCAAATCCTCT
AAATTTGAACCCTTGAATTAAGAGGACAAGTAAAAAATGTATAAACTATAAGAAGAAATT
AAGTCTAAAACTACTGTTTTGTAAAAATCTCTGAAAGAAAAGTAAAATGTAGAAAAAGAG
TATAACAAGTATAGAAATGAAGAATAATAGCTAACTAATCATTTATCCCAATTATCAGAA
GGTGGTGGTATGAAAGATGGTGAAGTCTTATTTTAAAGCATTGATCAAAGAATAAGTTCT
TCAGAGTAAGACCTCAAACATCAAGAAAGTATTCTCAAAGCTTAAAAAGCAATTGTGGAA
AAAGCTACACAAAGTAAGAAAACACTCGAAGAATAAATAAAAAAGATTGAGGGAGAAAGC
TAAGATAAGCTGAAAGAGCAAATTCAAAGCTAGTAAGAACTTTGCAATAATTTAGAATAA
TAAATCAGTGCTTTACTTCTCCGTAAACAACAATATATTTCAAAAGAGTACGAAATAGAT
TAAAAAAAGGAATTACTAGTAGTAAGCCCTGATTTTATCCAAAAAAATTCTCATCTTTCT
AAAGATAATTTAAAAGATAAGCTGAATAGAATTACTTAATAAACAACCATTAAGAAATAC
ACAGCAAAAGATAAAATTCTATTTGAAAAATTAAAAGATTTGGACGAGAAATATGAAGAA
TACAAATCCAAATACACTGAATTAACAAAAAATGAAGAATAAGCCAAAAATCTAATTGAT
TAATTTAAATCAAAATGTGAATAAACTATTAAAATGGCATTTTCTAAGTTTGAGCATTAT
ATGAAAAATTATTTCAAATAAATATCTTCTGCAGGTACAATAGACGTTAAACTTATGCAT
AATCATGAAATCAGTATATCAGTTGCTTTTAAATAAACTACAAATGAAACAAAAAAGACA
AATAGAAAAGAGCTAAGTGGAGGAGAAAAGAGTTGTCTTGCTATTCTTATTTTAATGGCT
CTATAGAGATGTGATCCAGCTCCATACTATATATTTGATGAATTTGATGCAGCATTAGAC
GCTGGTTATATTAGACCTATTGCAAAGATGTAAGTTAATTTTTAATTAAGTATTAAATTA
ATAACACATACTTATTTATTTATTTACTATTACGCAAAAGAATATCTGAAAATAGCTAAA
AGTCTTAATTTTTAATTGTTTCACACAAGTTTGAATTTTTATAAGCTTTACAACAAGAAA
ATTGTAAGTGCTTCTAGATATCACTAAAAGACAAAATAAGCGAGATAGAAGAGAAGACTT
TATCAGCTGCAATAAATTTTGTTAAAAATGGTTGAAAATGTGTTAAAAAGATAAATAGTT
TTTCCAAAAATTAGTCTCCATATAATTAATTATAAATTAAAATATTTTTCCATATATTTA
TTAACTGTATGTAATTTTAATCTAAATCATCAAATAGAGCATTCATTTTTTTTTTTAGCT
TACAAAATTTGTGGCTTATAATTCAATCTTATTTATTTAATTAATTTTAATTAAGAAGCT
GCTTAATTTTCTTGTGTTTATTTATGA

>TTHERM_00294810(gene)
ATGAGCATTAAATCAATATCTATAGAAAAATTTAAAAGTTACTCTAACTGCAAGATAGAA
GGACTCTCTGACAATATAAATATTCTGTATGGCAAGAATGGTTCTGGAAAATCTAATTTG
TTGGCTGGTACATAAAAAATATTACTTAGAAATTTAGCTTTTAATATATTTTTTTTGCTA
AAATTAGCTTTATCATTTATAAGTTCTGATTAGTACGATAGAGCTGATCGAGCATAATTA
ATGAAAGTAATATATATTTTCATAAATAAATTCTAAATTAAGAACTAACCTATTTTTATT
TTATATAGAATTATAAAGAAGGTGATCCTAAGGTCGAAATAGAGTTAGATAATTTAGTTA
AAATAGATAAAAAAGATATGGAAGATGAGCCAAAAGCACAAAAAGTTATTCCTGTACTCT
TTTTTATGAGTTTTATTAATTTAATTATTTTGTATTATTGTTCAAATTGATGAAAAATGT
TAATTTTTATTTAATATTCTTATTTAGACCAGCGGTGATAGTGTTTTATTAAGTAGAACT
TTAGAGTAAAGGGAGAATGTTTATAGGGTAGATGATAGAGTTGTTAATTTAAATTAGTTT
AATAATATTTTTGAGTGCTTTGGTCTTTCAAGAAAGAATCCTTTTACAATAGTTGCATAA
AATAGAATTTAAGAAATATCAAACATGAGTGATTCAGAAATCTATAAGTTGTTACAGCAA
GTAGCTGGAATAGAAGCTTTTATGAATAAATAAGAAAAAGCAGAAGAGCTTTTCGAAAAA
GCTTGTAATTTTTTATTTTAATACTAAATAATAATATGAAGGAAATATAATTTTAAAGAG
AGAGAAAAGGAAGGCATAGATTAATCCTTACAAGAAATAGAAGATAAAATAAGCTAGTTA
AGTGGTGAGAAAGAATAGTATGCACAAAATTAAGAATAGGAAATTATTATATAAAGGTAT
AAAAAACATTATTGCCTTTGAAAATATAAATATGTTTTTTTAATATTTTATTAGCTTGTA
ATCTATCTATTATGATAAATTGAAAGAAGAGCTTTAAAAGAAGAAATTAGAATGCAACAA
AGAAATCAATAATCAAAAATTGTAAGAAGAGAAGTAAAAGCTTCAGGATTTATAAAATTA
GAAAGAAGCTAAAAATGAAGAACTATTAAGATTTAAAGAAAAATTGCAAAGATTAACAGT
TATAGAAGAGCAAGTAAAATCAGATTAAATGAATCTTTAAAACAAAGTCAACAGTCTTGA
GTAGAATATCTAAAAATTAAAATCAATAAAAACTAACAAAGATGAAAAAGAAATTGAAGC
AAGATTAAAAGAAGTTAATATTTAATGCACTAAATTATAAAAAGATCTTGATGAAGTCAT
TGATAAAATAACAAATGAAAAAGATGGGTAAATAAATCATTTTAATATGAATAAAAAAAT
TTTTATTGATGTTTAATTTTGATAAAGGATTGACACCAAGCAGTAAGAATATGAGCAATT
AGTCTTAAGAGAAAAGTTTAAAACTTAGTAAGAAAAGCAAAGCTATTTTAATCAGAGAAT
CCAAGACATTAAACAAAGTATTAGTGAAAAATCATAAACTTAACAGAATCTTAAAGAGAA
AGTGAAAAAATCTGAATAAAGACTAAACTTAGTTAATTAAGAAATTGAAAAATTGTAAAA
TCAAATAAATAGTTTTTAAACTGAATCCAATAAGGCACAAAAAACTATAAATGGTAATTA
ATTAATTAAAATATTTAAATTATTTTTATTAACTTAAAATTAGATAAAAAGAATTAAATC
TAAAAATTGAGACAAGAGTAGCTTGAAAAGAGAAAGACAATTAATGATAAAAAAATAGAG
TTGGAAGATTTAAACAACTAAATAAAAAAGAGAGTTGATGATATACAAAAGTAGTTGAAA
TCAGGATTAATCCAAGCAATTGAGCAAATCGAGGAATCAATATAAAAAGAAGGTATTTAG
GGATATAAAGGACTGCTTATAGATCATCTTTAATTTAATTCTGCACTTACTTATGCATAT
GATATTGCTCAAAAAGGTATTTCACATTTTTTATTTTTCTTGCAAATATTTATTTTTTTA
TAAACTTATTGCTAGGAAAATTATTTTCTTTGATAGTCGATAATCAAAATACTGCCTCTT
TAATAATTGATATTGTTAAGAAATTGAAGATTAAAACATCAAATTTAAATATTATTCCCC
TAGATTGGGTTGAAGATGATATTGATGATGAAAAAGAAAACTAAATTGCAGGATTCGGAT
TTTAAAAGCTATTTGATACTAGGTATGTTAAGGCAAAAGGAGATCATGCAGATGATATAA
AAAGGTTAGCTAAGAATATTTTTGAAAAATATGGTGTAATTAAAGAGTATGAACATGCCC
TAGAGGTAGCATCTTAATTTAAAGTAAACTGCATTACAGAGAAGAGATAAATTGTTTATA
GTGGAGGTTTTATTTCTCATGTTGGTTTTTGTACTGTGGCTAAAGTAGATAAAATAACAC
TTTACAATGAATACAAAAGCTTTAAAGCTAAGAAAGATGCTATTGCTAAAGAAATAGAGC
AACTAGAGAAGTCTATGAATGATATTTAATTGTAATAAAATGATATAAATTCAAATGTAA
GCAAAGAATAAGCTAGCTTAGCAAAATAGAGTAACACTATATTTATGAATCGTTAACTAA
TTAAATCATCTGAAGTAGAGAAAAAAGTATTGACTGATGAGTTAAACGAAACAAATTAAC
TCCTATAGTCTTTTTCTTAATAACTTAAAGATTTAGAATAAGAGAAAATAGGTTTAGAAA
ATACTAGCAAATCCTCTAAATTTGAACCCTTGAATTAAGAGGACAAGTAAAAAATGTATA
AACTATAAGAAGAAATTAAGTCTAAAACTACTGTTTTGTAAAAATCTCTGAAAGAAAAGT
AAAATGTAGAAAAAGAGTATAACAAGTATAGAAATGAAGAATAATAGCTAACTAATCATT
TATCCCAATTATCAGAAGGTGGTGGTATGAAAGATGGTGAAGTCTTATTTTAAAGCATTG
ATCAAAGAATAAGTTCTTCAGAGTAAGACCTCAAACATCAAGAAAGTATTCTCAAAGCTT
AAAAAGCAATTGTGGAAAAAGCTACACAAAGTAAGAAAACACTCGAAGAATAAATAAAAA
AGATTGAGGGAGAAAGCTAAGATAAGCTGAAAGAGCAAATTCAAAGCTAGTAAGAACTTT
GCAATAATTTAGAATAATAAATCAGTGCTTTACTTCTCCGTAAACAACAATATATTTCAA
AAGAGTACGAAATAGATTAAAAAAAGGAATTACTAGTAGTAAGCCCTGATTTTATCCAAA
AAAATTCTCATCTTTCTAAAGATAATTTAAAAGATAAGCTGAATAGAATTACTTAATAAA
CAACCATTAAGAAATACACAGCAAAAGATAAAATTCTATTTGAAAAATTAAAAGATTTGG
ACGAGAAATATGAAGAATACAAATCCAAATACACTGAATTAACAAAAAATGAAGAATAAG
CCAAAAATCTAATTGATTAATTTAAATCAAAATGTGAATAAACTATTAAAATGGCATTTT
CTAAGTTTGAGCATTATATGAAAAATTATTTCAAATAAATATCTTCTGCAGGTACAATAG
ACGTTAAACTTATGCATAATCATGAAATCAGTATATCAGTTGCTTTTAAATAAACTACAA
ATGGTATTTTTAAAGCATCAAAAAAAAGTATTTAACAAAATATTTATTATATTAGAAACA
AAAAAGACAAATAGAAAAGAGCTAAGTGGAGGAGAAAAGAGTTGTCTTGCTATTCTTATT
TTAATGGCTCTATAGAGATGTGATCCAGCTCCATACTATATATTTGATGAATTTGATGCA
GCATTAGACGCTGGTTATATTAGACCTATTGCAAAGATGTAAGTTAATTTTTAATTAAGT
ATTAAATTAATAACACATACTTATTTATTTATTTACTATTACGCAAAAGAATATCTGAAA
ATAGCTAAAAGTCTTAATTTTTAATTGTTTCACACAAGTTTGAATTTTTATAAGCTTTAC
AACAAGAAAATTGTAAGTGCTTCTAGGTAAATATTGAATTTCAATTACTCTATTAAAATT
AATTTAAATAATAGATATCACTAAAAGACAAAATAAGCGAGATAGAAGAGAAGACTTTAT
CAGCTGCAATAAATTTTGTTAAAAATGGTTGAAAATGTGTTAAAAAGATAAATAGTTTTT
CCAAAAATTAGTCTCCATATAATTAATTATAAATTAAAATATTTTTCCATATATTTATTA
ACTGTATGTAATTTTAATCTAAATCATCAAATAGAGCATTCATTTTTTTTTTTAGCTTAC
AAAATTTGTGGCTTATAATTCAATCTTATTTATTTAATTAATTTTAATTAAGAAGCTGCT
TAATTTTCTTGTGTTTATTTATGA

>TTHERM_00294810(protein)
MSIKSISIEKFKSYSNCKIEGLSDNINILYGKNGSGKSNLLAALSFISSDQYDRADRAQL
MKNYKEGDPKVEIELDNLVKIDKKDMEDEPKAQKVIPTSGDSVLLSRTLEQRENVYRVDD
RVVNLNQFNNIFECFGLSRKNPFTIVAQNRIQEISNMSDSEIYKLLQQVAGIEAFMNKQE
KAEELFEKAQREKEGIDQSLQEIEDKISQLSGEKEQYAQNQEQEIIIQSLQSIYYDKLKE
ELQKKKLECNKEINNQKLQEEKQKLQDLQNQKEAKNEELLRFKEKLQRLTVIEEQVKSDQ
MNLQNKVNSLEQNIQKLKSIKTNKDEKEIEARLKEVNIQCTKLQKDLDEVIDKITNEKDG
IDTKQQEYEQLVLREKFKTQQEKQSYFNQRIQDIKQSISEKSQTQQNLKEKVKKSEQRLN
LVNQEIEKLQNQINSFQTESNKAQKTINDKKNQIQKLRQEQLEKRKTINDKKIELEDLNN
QIKKRVDDIQKQLKSGLIQAIEQIEESIQKEGIQGYKGLLIDHLQFNSALTYAYDIAQKG
KLFSLIVDNQNTASLIIDIVKKLKIKTSNLNIIPLDWVEDDIDDEKENQIAGFGFQKLFD
TRYVKAKGDHADDIKRLAKNIFEKYGVIKEYEHALEVASQFKVNCITEKRQIVYSGGFIS
HVGFCTVAKVDKITLYNEYKSFKAKKDAIAKEIEQLEKSMNDIQLQQNDINSNVSKEQAS
LAKQSNTIFMNRQLIKSSEVEKKVLTDELNETNQLLQSFSQQLKDLEQEKIGLENTSKSS
KFEPLNQEDKQKMYKLQEEIKSKTTVLQKSLKEKQNVEKEYNKYRNEEQQLTNHLSQLSE
GGGMKDGEVLFQSIDQRISSSEQDLKHQESILKAQKAIVEKATQSKKTLEEQIKKIEGES
QDKLKEQIQSQQELCNNLEQQISALLLRKQQYISKEYEIDQKKELLVVSPDFIQKNSHLS
KDNLKDKLNRITQQTTIKKYTAKDKILFEKLKDLDEKYEEYKSKYTELTKNEEQAKNLID
QFKSKCEQTIKMAFSKFEHYMKNYFKQISSAGTIDVKLMHNHEISISVAFKQTTNETKKT
NRKELSGGEKSCLAILILMALQRCDPAPYYIFDEFDAALDAGYIRPIAKMQVNFQLSIKL
ITHTYLFIYYYAKEYLKIAKSLNFQLFHTSLNFYKLYNKKIVSASRYHQKTKQARQKRRL
YQLQQILLKMVENVLKRQIVFPKISLHIINYKLKYFSIYLLTVCNFNLNHQIEHSFFFLA
YKICGLQFNLIYLINFNQEAAQFSCVYL