Identifiers and Description

Gene Model Identifier

TTHERM_00378750

Standard Name

TTLL3E (Tubulin Tyrosine Ligase-Like )

Aliases

PreTt10329 | 40.m00214

Description

TTLL3E tubulin-tyrosine ligase family protein; Related to tubulin tyrosine ligase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• tubulin-tyrosine ligase activity (IEA) | GO:0004835

Biological Process

• cellular protein modification process (IEA) | GO:0006464
• peptidyl-amino acid modification (ISS) | GO:0018193

Domains

• ( PF00922 ) vesiculovirus phosphoprotein
• ( PF03133 ) Tubulin-tyrosine ligase family
• ( PF05672 ) E-MAP-115 family
• ( PF06394 ) Pepsin inhibitor-3-like repeated domain
• ( PF06658 ) Protein of unknown function (DUF1168)
• ( PF07813 ) LTXXQ motif
• ( PF09026 ) Centromere protein B dimerisation domain
• ( TIGR02863 ) small, acid-soluble spore protein, SspJ

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_00099.1	9.997093137033517e-262
	Description: tubulin-tyrosine ligase (1051 aa)
Oxytricha	Contig8461.0.g60	1.999126889527329e-167
	Description: Tubulin-tyrosine ligase family
Stentor Coeruleus	SteCoe_5511	1.5007857627073948e-41
	Description: None
DictyBase	DDB_G0281541	2.0008113830639685e-30
	Description: DDB_G0281541 on chromosome: 3 position 4627625 to 4629265
WormBase	WBGene00044187	9.99967697349061e-30
	Description: locus:ttll-9 status:Partially_confirmed UniProt:Q564U4 protein_id:CAI79169.1
SGD	YBR094W	0.000000600201742947405
	Description: PBY1 Putative tubulin tyrosine ligase associated with P-bodies

General Information

No Data fetched for General Information

Associated Literature

1. Ref:15890843: Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM, Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S, Gaertig J, Eddé B (2005) Tubulin polyglutamylase enzymes are members of the TTL domain protein family. Science (New York, N.Y.) 308(5729):1758-62

Sequences

>TTHERM_00378750(coding)
ATGAGTTCTTTAGATGAAGGTTTAAAATAAATGAGCCAATAGGAATATAGAAACGAAGAA
TAAAATCAGGAAGGCAATTAGGAGGATTTAAACAATCAAAATGATCACAATTTAAATAAT
AATGAATTAGATAGCCTGTCTTCTCCTCCATCAGACAATTATAATGAAGAAGAATTTGAG
TAAGAAGATGATATTAAACCTGACATAAAAATATATTAAAATGCATCACAAAATAACATA
TCGTAGACATAAAGGATAAGTTAAACTTAACTACCATAGCAGTAAGGAGGAGGGGGAAAA
AGGAATTCGTCTCTTTTGCAAAAAGAACACTATCATCAAAAAAATTAAGAGATCATATAA
AAACTGATGGAGAAAAAGAAAAAAGAATAAGAAGAAAAAGAAAAAAAAGAATTGAAATTA
AAAAAAAGAGAAGATAAATTGCGTAAGCGCATGCTTGAAGAAGCAGCAAAGATTAGAGAG
CAAAAGGAAGTAAATTTAGAATCATAAACTGAATAAAGCGATCACTCAAACGTCACAAAA
TCAAAAAAACTCAAATTCAAGAGTGTATAAGATATTTACTAACTTGTAGTCATATAAGGA
AAATATCAAAGAGAGTAATTAACAGATAAGTAGCAGTAAGAACTCAACGAATTTGAAAGT
AGGCTGAACGAAGAAAAAACAACGATAATTAAGATGCAATAAGTTTACAGATCACGTCAA
ATTACTTTTTTAGAGGAGTTAAAGAAAAAATAGGAGAAAAAAAAGCAAGAAGAGGAATAA
CAGAAACTAAAGCAGGAGAAAATACAAACCAAATTAAGGGAATAATATGAAAATGTGAAT
TCTAATCTCTATGCTGAAACTGAGTTATTCAAGTAAAAAAAGCAAGAAATTACCAAGGTC
AGCACTTAGAAATAGCTTGTAAGAGCATCATCTGCAGAAGCTAAAGAAGATAACATTTAA
ATTACTTCTCCTAAGTTAAATTCTACCAAGTCTTTATCTTCATAAATTACAAGAAAAACA
AACGATGCTAAAAAAGTAGAAAAACTCCCAAAAATTAAAGATTCAAATAAGGAGAATCAT
TCCAAAGAAAGAAATGAAGATAATGAAGAAGGGGATGATGGAGAATATGAATGTGACGAA
GGTGATGAAGGTGCAAGCGATGGAGAAGATGAAGATGATGGAAATGGTAGTGCCATTAAA
AGAAAGCTTAGAAAATATCCCTTTATCACTGATTTAGAGTTATGGAAAAAAAAACAAAGA
TTGCCTGCTGACATTAAAGTGTTCATTGTTACTGGAGGCTATCACGACATATCAAAAGCT
TTGAAAAAAAGAGGTTGGATTGCAAACCCTGATACAAAAAGTCCTTGCTACAATTTCAGA
TGGAGCTTACAAACTAAGGACATAGATTATGAAAATTTAAAGGATTTCTAAATAGTTAAT
CACTTTTAAAAGAGTGCATGTATCACAACCAAAGTTGGGTTATGCAAAAGTCTAAGAAAT
CTAGTTTGGCATGAAAATGTAGATATCGATACATTCTATCCTAGATGTTTTGATTTAAAC
GATACTGAAGATTTCGAAAATTTTGTCGAAGAGTTTAAATCCTCTAAGGCTGAGAGCATC
CTAAAGAGATACATGAGAATGTACTTTGAAAAAGATCCAGATATTGAAAAAATAAAAAAG
TAGGCTGTAATTGCATTTAATGTTTGTGAAAGAAAAATGAAAGAATTAGATGAAATTATA
GATGATCCAAACTCAATATAGCTGATAACTAAAAAAGAGTGGAATATACTCTCAGCTGAT
GAACTTACTGAAGAAAAGCTCGCTTAAAAGAAATATGAGTAATGGCTAGAAAGGATTGAA
GGTAAAAATAAATAAAAACCTAAAAAGAAAAAGAAGAAATCAAAGAAGGATAAACAATAA
GGAGATACAGAGAAGAAAGAAGAGGAAGAAGGAGAGGCTGAAGATGAAGAAGAGGATGAA
GAAGATGAGGAAGAAGAAGAAAAGCAAATGGATGAATTCACTTTGAAGGTTCATCAAATC
CTTAAAAGGTATAAAGTAAAGTATCCTTAAGATTGCTTGACAGGTGAAGATAATGTCTGG
ATTATAAAACCTGCTGGACTTTCAAGAGGCAGAGGAATTACGTGCTACAATAATTTAGTT
GAAATTCTTGATCATGTTAAGTCTAAGGAGTCATAATGGGTAATTCAGAAATATATAGAA
AATCCCTTGATCATAAAAAAAAGAAAGTTTGATATTAGAGTTTGGATTCTTGTCACTGAT
TGGAATCCATTGACTATTTGGCACTATACAGACTGTTATGTGAGATTCAGTGTTGATGAT
TATGATACTGAAAACCTCCAAAATAAATTTACTCACTTAACAAATAACATGGTTTCTAAG
CTTAAGTAAAGGGATGAAAAAGACGATATAACAGAGTTAGGAAGCATGTATTTCAAAGAG
AATTTTATCAACTATTTAAAAGAAAAAGAAGGATATGATGTATTTACAGATAAGATTGAG
CCTTAGATTGTGAGGGCAATTATTATGTCTTTGAAGAGTGTTTAGGACAATATAGAAAAT
CGTAAAAATAGTATTGAAATGTATGGGTATGATTTCATGGTTGATGATTTGTACAATACT
TGGCTCATTGAAATTAACTCTTCTCCCTCTATGGAATACTCAACACCAGTGACTGAAAGG
TTAGTCAAAGCTGTTTCTGAAGATATAGTAAAGGTGGTTATAGATTATGGAATGGAAAAG
AGTAAAAAAGCAAGGAAAAATATAGAAACAGGGGCTTTTAAGAGAATATATAAAGGCAAA
TATGTTGAAGAAAAAACAAATGTAGTCGGTCTAAATTTAATATGTGAAGGTGTAGCATTA
AAAAAAGGAAAAAAGAATTCAAACGTTGCAAAAGTTAATAATCTAAAACCTAATTTCTCA
TGA

>TTHERM_00378750(gene)
ATGAGTTCTTTAGATGAAGGTTTAAAATAAATGAGCCAATAGGAATATAGAAACGAAGAA
TAAAATCAGGAAGGCAATTAGGAGGATTTAAACAATCAAAATGATCACAATTTAAATAAT
AATGAATTAGATAGCCTGTCTTCTCCTCCATCAGACAATTATAATGAAGAAGAATTTGAG
TAAGAAGATGATATTAAACCTGACATAAAAATATATTAAAATGCATCACAAAATAACATA
TCGTAGACATAAAGGATAAGTTAAACTTAACTACCATAGCAGTAAGGAGGAGGGGGAAAA
AGGAATTCGTCTCTTTTGCAAAAAGAACACTATCATCAAAAAAATTAAGTATTAATTTAA
TTGATTTGATCATTTTAACATAGAAAAGAACGATGCTCATCTTATAAATAGGAGATCATA
TAAAAACTGATGGAGAAAAAGAAAAAAGAATAAGAAGAAAAAGAAAAAAAAGAATTGAAA
TTAAAAAAAAGAGAAGATAAATTGCGTAAGCGCATGCTTGAAGAAGCAGCAAAGATTAGA
GAGCAAAAGGAAGTAAATTTAGAATCATAAACTGAATAAAGCGATCACTCAAACGTCACA
AAATCAAAAAAACTCAAATTCAAGAGTGTATAAGATATTTACTAACTTGTAGTCATATAA
GGAAAATATCAAAGAGAGTAATTAACAGATAAGTAGCAGTAAGAACTCAACGAATTTGAA
AGTAGGCTGAACGAAGAAAAAACAACGATAATTAAGATGCAATAAGTTTACAGATCACGT
CAAATTACTTTTTTAGAGGAGTTAAAGAAAAAATAGGAGAAAAAAAAGCAAGAAGAGGAA
TAACAGAAACTAAAGCAGGAGAAAATACAAACCAAATTAAGGGAATAATATGAAAATGTG
AATTCTAATCTCTATGCTGAAACTGAGTTATTCAAGTAAAAAAAGCAAGAAATTACCAAG
GTCAGCACTTAGAAATAGCTTGTAAGAGCATCATCTGCAGAAGGTAAATGAATTATACAT
TTCAGCTAATTTTTATTTATTTATTTGTTATTTATTTTGAATAATATATAACAATAATTT
ATGTTTAAGAGAATAAATAAATAAATAATTATACTGTTACAACCTTATGTTTTGATAAAT
TACTAATCATTTGTATTTTCTATATTGAATAGGAGATAAAGAGAAAGATGATAAGAAGGA
TATCGCCAAAAAAATATAGTAGAAGAATCAAGAGTATATTGAAAAGTTGAAAGAAAAAAG
AGATAAGAGATTGCTAAAGAGGAAGAGGAAAAGAAGAAAAAGGAGCAACTCAAAGAAAAA
ATGAAAGATTTTGTCCTTGTCAATATCAAAAAAGACATTGAAAATGGAGTTTTTTTTGTT
GATGTTCCAGAAAAAAAACCTAAAAAAGAGAAGAAAAAGAATGAATGTATTTTTTTACTT
TAACTATTCTAATAATATTAAAATTTTGGAAAATAAATTATAGCTAAAGAAGATAACATT
TAAATTACTTCTCCTAAGTTAAATTCTACCAAGTCTTTATCTTCATAAATTACAAGAAAA
ACAAACGATGCTAAAAAAGTAGAAAAACTCCCAAAAATTAAAGATTCAAATAAGGAGAAT
CATTCCAAAGAAAGAAATGAAGATAATGAAGAAGGGGATGATGGAGAATATGAATGTGAC
GAAGGTGATGAAGGTGCAAGCGATGGAGAAGATGAAGATGATGGAAATGGTAGTGCCATT
AAAAGAAAGCTTAGAAAATATCCCTTTATCACTGATTTAGAGTTATGGAAAAAAAAACAA
AGATTGCCTGCTGACATTAAAGTAAATTTACTTTTTCATTTATCTCTCTTAAAATTTAAT
TTTCAATAAAAATAGGTGTTCATTGTTACTGGAGGCTATCACGACATATCAAAAGCTTTG
AAAAAAAGAGGTTGGATTGCAAACCCTGATACAAAAAGTCCTTGCTACAATTTCAGATGG
AGCTTACAAACTAAGGACATAGATTATGAAAATTTAAAGGATTTCTAAATAGTTAATCAC
TTTTAAAAGAGTGCATGTATCACAACCAAAGTTGGGTTATGCAAAAGTCTAAGAAATCTA
GTTTGGCATGAAAATGTAGATATCGATACATTCTATCCTAGATGTTTTGATTTAAACGAT
ACTGAAGATTTCGAAAATTTTGTCGAAGAGTTTAAATCCTCTAAGGTAAATAAATAAATA
AATAAAAAAAATTATTTTTTCTTAATAATTTAAACAAACTATAACAGGCTGAGAGCATCC
TAAAGAGATACATGAGAATGTACTTTGAAAAAGATCCAGATATTGAAAAAATAAAAAAGT
AGGCTGTAATTGCATTTAATGTTTGTGAAAGAAAAATGAAAGAATTAGATGAAATTATAG
ATGATCCAGTAATAAATAGTTATATTTTTTTATAAGTGTTTGTTATAATTTTTTTTAAAG
AACTCAATATAGCTGATAACTAAAAAAGAGTGGAATATACTCTCAGCTGATGAACTTACT
GAAGAAAAGCTCGCTTAAAAGAAATATGAGTAATGGCTAGAAAGGATTGAAGGTAAAAAT
AAATAAAAACCTAAAAAGAAAAAGAAGAAATCAAAGAAGGATAAACAATAAGGAGATACA
GAGAAGAAAGAAGAGGAAGAAGGAGAGGCTGAAGATGAAGAAGAGGATGAAGAAGATGAG
GAAGAAGAAGAAAAGCAAATGGATGAATTCACTTTGAAGGTTCATCAAATCCTTAAAAGG
TATAAAGTAAAGTATCCTTAAGATTGCTTGACAGGTGAAGATAATGTCTGGATTATAAAA
CCTGCTGGACTTTCAAGAGGCAGAGGAATTACGTGCTACAATAATTTAGTTGAAATTCTT
GATCATGTTAAGTCTAAGGAGTCATAATGGGTAATTCAGAAATATATAGAAAATCCCTTG
ATCATAAAAAAAAGAAAGGTAAATAAATAAATTGATTTTTAGAAATTAATAAAAAAATTA
TTTCTTAATAATATTTTTTAGTTTGATATTAGAGTTTGGATTCTTGTCACTGATTGGAAT
CCATTGACTATTTGGCACTATACAGACTGTTATGTGAGATTCAGTGTTGATGATTATGAT
ACTGAAAACCTCCAAAATAAATTTACTCACTTAACAAATAACATGGTTTCTAAGCTTAAG
TAAAGGGATGAAAAAGACGATATAACAGAGTTAGGAAGCATGTATTTCAAAGAGAATTTT
ATCAACTATTTAAAAGTATTAATTTTATTTATTTATTTTAGACTTTACTTTAATCTACTT
TTAAGGAAAAAGAAGGATATGATGTATTTACAGATAAGATTGAGCCTTAGATTGTGAGGG
CAATTATTATGTCTTTGAAGAGTGTTTAGGACAATATAGAAAATCGTAAAAATAGTATTG
AAATGTATGGGTATGATTTCATGGTTGATGATTTGTACAATACTTGGCTCATTGAAATTA
ACTCTTCTCCCTCTATGGAATACTCAACAGTAATAAATAAATATTTAGTTGATTCATAAA
TTTGAATAATTATTTTTTAATTATTTTAGCCAGTGACTGAAAGGTTAGTCAAAGCTGTTT
CTGAAGATATAGTAAAGGTGGTTATAGATTATGGAATGGAAAAGAGTAAAAAAGCAAGGA
AAAATATAGAAACAGGGGCTTTTAAGAGAATATATAAAGGCAAATATGTTGAAGAAAAAA
CAAATGTAGTCGGTCTAAATTTAATATGTGAAGGTGTAGCATTAAAAAAAGGAAAAAAGA
ATTCAAACGTTGCAAAAGTTAATAATCTAAAACCTAATTTCTCATGA

>TTHERM_00378750(protein)
MSSLDEGLKQMSQQEYRNEEQNQEGNQEDLNNQNDHNLNNNELDSLSSPPSDNYNEEEFE
QEDDIKPDIKIYQNASQNNISQTQRISQTQLPQQQGGGGKRNSSLLQKEHYHQKNQEIIQ
KLMEKKKKEQEEKEKKELKLKKREDKLRKRMLEEAAKIREQKEVNLESQTEQSDHSNVTK
SKKLKFKSVQDIYQLVVIQGKYQREQLTDKQQQELNEFESRLNEEKTTIIKMQQVYRSRQ
ITFLEELKKKQEKKKQEEEQQKLKQEKIQTKLREQYENVNSNLYAETELFKQKKQEITKV
STQKQLVRASSAEAKEDNIQITSPKLNSTKSLSSQITRKTNDAKKVEKLPKIKDSNKENH
SKERNEDNEEGDDGEYECDEGDEGASDGEDEDDGNGSAIKRKLRKYPFITDLELWKKKQR
LPADIKVFIVTGGYHDISKALKKRGWIANPDTKSPCYNFRWSLQTKDIDYENLKDFQIVN
HFQKSACITTKVGLCKSLRNLVWHENVDIDTFYPRCFDLNDTEDFENFVEEFKSSKAESI
LKRYMRMYFEKDPDIEKIKKQAVIAFNVCERKMKELDEIIDDPNSIQLITKKEWNILSAD
ELTEEKLAQKKYEQWLERIEGKNKQKPKKKKKKSKKDKQQGDTEKKEEEEGEAEDEEEDE
EDEEEEEKQMDEFTLKVHQILKRYKVKYPQDCLTGEDNVWIIKPAGLSRGRGITCYNNLV
EILDHVKSKESQWVIQKYIENPLIIKKRKFDIRVWILVTDWNPLTIWHYTDCYVRFSVDD
YDTENLQNKFTHLTNNMVSKLKQRDEKDDITELGSMYFKENFINYLKEKEGYDVFTDKIE
PQIVRAIIMSLKSVQDNIENRKNSIEMYGYDFMVDDLYNTWLIEINSSPSMEYSTPVTER
LVKAVSEDIVKVVIDYGMEKSKKARKNIETGAFKRIYKGKYVEEKTNVVGLNLICEGVAL
KKGKKNSNVAKVNNLKPNFS