Identifiers and Description

Gene Model Identifier

TTHERM_00387050

Standard Name

LIG4 (DNA ligase IV)

Aliases

PreTt24799 | 41.m00206

Description

LIG4 ATP-dependent DNA ligase; DNA ligase required for nonhomologous end-joining (NHEJ)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Cellular Component

• photosystem II antenna complex (IEA) | GO:0009783

Molecular Function

• glutathionylspermidine synthase activity (IEA) | GO:0008885

Biological Process

• glycosphingolipid biosynthetic process (IEA) | GO:0006688
• negative regulation of protein kinase activity (IEA) | GO:0006469
• response to auxin (IEA) | GO:0009733
• response to jasmonic acid (IEA) | GO:0009753

Domains

• ( PF00533 ) BRCA1 C Terminus (BRCT) domain
• ( PF01068 ) ATP-dependent DNA ligase domain
• ( PF01331 ) mRNA capping enzyme, catalytic domain
• ( PF01779 ) ribosomal L29e protein family
• ( PF04675 ) DNA ligase N terminus
• ( PF04679 ) ATP dependent DNA ligase C
• ( TIGR00574 ) DNA ligase I, ATP-dependent (dnl1)
• ( TIGR02776 ) DNA ligase D
• ( TIGR02779 ) DNA polymerase LigD, ligase domain

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_04427.1	9.997093137033517e-262
	Description: DNA ligase IV (1028 aa)
Oxytricha	Contig17485.0.g101	6.001048086731027e-152
	Description: ATP dependent DNA ligase domain
DictyBase	DDB_G0292760	9.995094197784295e-101
	Description: lig4 on chromosome: 6 position 2052081 to 2055347
Stentor Coeruleus	SteCoe_12774	1.1677812485237086e-60
	Description: None
SGD	YOR005C	9.998397555368434e-52
	Description: DNL4 DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth
WormBase	WBGene00002985	2.0003218023735366e-33
	Description: locus:lig-1 DNA ligase 1 status:Partially_confirmed UniProt:Q27474 protein_id:CAA98242.2

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00387050(coding)
ATGCAAAACTATTATAAATGGCATAAGATAAAATAAGAATAAAATCAAGAATTGTCTGTT
AATATAAAGCCAATTTCTTCATCAAAGATGAAACAAAGTGATATTTCTACTAGGAAGAAA
AAAGCTTAAGAGTATAATATGGATTTTGATGAATTTTAGCAAGAGGATTCTAAAATTAAC
TAAAATTCTGATAATTTTCACTTTGGTGATTCAGCAGATGAATATGGTATTGATTCACCA
AAAATGAAAAGAGAAAAAGCAGTTAAAGAAGAAGATAATACCTTTCGCTTAGAAATTAAA
AAATCTCCTATCCTAGAGAAAACACTCTTTTCATTTTTAGTCAAATTTTATAATTAAGTC
TAGCAATCTAAAAAAGGGCAAAGAAAAAAATTTGTATAAAGATTCATTGACTCTACATTT
AAAACAAATAGATGTCCATCTTACACATTTACTATCCTTAGGTTAATAATGCCTCATCAT
GATAAATAACGTCTTAATTATGGCTTAAACTATAAAAATTTAGCTAAAGTTTTAAGCGAA
GTGTTTGCCTTATCAGAAGATAAACGTCAATAGCTTTTGAATTATAAAAGACCTTTAAAA
GACAACTAGCAAGTAGTTGGTGATTTTGGTGAAGTTGTATAAAATGTTTTGTAAGCATTT
ACTTAGAAAGCCACACTAACAATCAACGATGTGGATAGATGTCTTGATGAGCTTGCATAA
CCTCAAAATAGAGATCTAGCATCCAAAGAAAAAGTTTTAAGAAACTGCTTGAAGAATGCA
ACATCAGAAGAAATAAAATGGATTTCACGTTTGATCTTAAAGGACCTTAATCTTGGTATT
AATCACGAAATAATACTTGCACTTTTTCATCCTGATGCAGTAGTATTATTTAATTCTACT
TCTAGTCTTTGGGAGGTTTGCAAGGAATTTGTAGATCCAAATCATAAATTATCTAATGTC
CTTAGGCTATTTCATCCTATAAAACCTATGCTTGCAGGACGTAAGACTCTCAAAAGTATT
GAAGCTATTCTTAAAGGTAAAAACTATTTAGTTGAAACAAAATTTGATGGGGAGAGAATT
TAGTGTCATGTATCTCCTGAATCTTTAATGTTTTTCACTAGAAACTCAAACAATTATACA
AATATTTATGAAAGAATGATAGAGCATGTTAGAAGAAGTTTAAAAGATGCTGTTCATAGT
TGTATTTTAGATGGAGAAATGGTTGTAGTAAATAAAATAACAGGATAAAGAGTTTAATTT
GGTCTTAATAAAACTGTTGCAATGGAAAGAGAGGATGATGAATTATGTATATGTTATAAA
ATTTTTGACATTTTATATTTGAAGACTAAAGATAATAAAGAATATGCACTGACAGAATAC
ACATTGCAATATAGAAAAAAAATTTTAGAAAATTTAATTGACAATCAATAAGACAGAGTT
GAAGTTATTTTTGGTAGAGAATACTCAGATATAAATGACATACTGACTGAATTTAATGAG
GCAATACATAGAAACGATGAAGGTATAGTCATAAAGCAGCTCGATACTCTGTATTACCCA
GATGATAGATCTGATAAGTGGATTAAAATGAAAGGTGACTACTATGAAGGAATAATAGAT
ACCTTAGATTTGATAGTTATTGGAGGATATTTTGGTGAAAAGTCTTATAAAATTAATGGC
ATAGGAGATTGGACAGATCATATCACACATTATCTTGTTGCTGTAGCGAAAAAGATTGAT
CTACAAAACCCCTCTAACTCTATACTTGTGCCTTTTGCTAAAGTGGGAGCAGGTTTTACA
GCTAGAGACTATGCTGATATAAAAGCTAGAATGAGAGATCAATGGGTAAGAACTAATCAT
TCAAATAAAACGCCTTCTTTCATCATATAAAACTGGAAACCTGGAGAAAAAGATAAGCCA
GATGCATATATTTTATCTCCTCAAAACTCTCTTATTTTAGAGATTAGGGCAACTGAAATT
ATATAATCTTCTTAATATCCGACCAACTACACCTTAAGATTTCCGAGATTTGAAAAATTT
AGAAGAGATAAAGATTGGTTTGATTGCATGAAATTTAATGAAATTATAGAAATGACTTAA
AATTTAAAGAAAAAAGAATAAAAAGAGAGTGACAAAGAAGATAATGCAAGCGATGAAGAG
TAGGACGAAAATGGAGGAAAATTAAAGAAAAAAAGAAAAGGGTAAAATGGAGAAGAGATA
GAAGTAAATAGACAAGGTAGAAAGCCAAACTGGAAGACCAATAAAGTTATGGCTCAATAT
CTTGATATTGATGTTTCTGATGTCAAAGTAGAATCAAATATATTTAATAACTTTGTATTT
AATATAATTAATTTACCTCATGAAGTATCCTTGAGTGAGGAAAAGATATTGTTAGAGAAA
GCCTAGATTGAAAAAGGTATAGTTGCTAATGGTGGTAAAAAAGTATAAAATGATAGCAAT
CTTGTAACTCATTACATAGCTTCACATTATGATTTTAAAGTTTAAGTAATTGGTGATCAC
TATAAAGTAAATGTTCTATCCTTATAATGGGTAAAAGACTGTATCAAAAAAAAAACTTTA
TTAGATTACTCTCCCCGCTACATTATATATGGTTAAGATTAATTGCTTGAGAGAAATAAA
TTGCTTTATGATTAATATGGAGATTCTTATTACAAAGATGTTGATGAAGATGAGTTATTG
GATATTTTAAAATCTATGAAAATTGATTAAATAGAAGAAGAATTCTAGGAGAATGAAGAG
TTTGAAGAGGCTGTTAAAGATATTATTTCCATGAAAAACCAACTTTTCAAAGAATGTTTT
CCGTAAGGATAAACTTATTGCTTTTATAATGCAAATGATAAATTGAATTCAGATATAGAC
TTAAGATATTTAGTTGATCTAATTTAATTTAGTGGAAATTAAGTTGTATTTGACTTATAG
GACGAAATTGATTACATAGTGGCTTTAGATTATAGTGAAGCTGAAAACGAAAAAATTATT
ACCTTCAGAGAAAAAAACAGAAGTATGGAAGTTATAACTCCTAAAAACTTGTTGAATAAT
TTTGGAATAGCTCTAGAATGA

>TTHERM_00387050(gene)
ATGCAAAACTATTATAAATGGCATAAGATAAAATAAGAATAAAATCAAGAATTGTCTGTT
AATATAAAGCCAATTTCTTCATCAAAGATGAAACAAAGTGATATTTCTACTAGGAAGAAA
AAAGCTTAAGAGTATAATATGGATTTTGATGAATTTTAGCAAGAGGATTCTAAAATTAAC
TAAAATTCTGATAATTTTCACTTTGGTGATTCAGCAGATGAATATGGTATTGATTCACCA
AAAATGAAAAGAGAAAAAGCAGTTAAAGAAGAAGATAATACCTTTCGCTTAGAAATTAAA
AAATCTCCTATCCTAGAGAAAACACTCTTTTCATTTTTAGTCAAATTTTATAATTAAGTC
TAGCAATCTAAAAAAGGGCAAAGAAAAAAATTTGTATAAAGATTCATTGACTCTACATTT
AAAACAAATAGATGTCCATCTTACACATTTACTATCCTTAGGTTAATAATGCCTCATCAT
GATAAATAACGTCTTAATTATGGCTTAAACTATAAAAATTTAGCTAAAGTTTTAAGCGAA
GTGTTTGCCTTATCAGAAGATAAACGTCAATAGCTTTTGAATTATAAAAGACCTTTAAAA
GACAACTAGCAAGTAGTTGGTGATTTTGGTGAAGTTGTATAAAATGTTTTGTAAGCATTT
ACTTAGAAAGCCACACTAACAATCAACGATGTGGATAGATGTCTTGATGAGCTTGCATAA
CCTCAAAATAGAGATCTAGCATCCAAAGAAAAAGTTTTAAGAAACTGCTTGAAGAATGCA
ACATCAGAAGAAATAAAATGGATTTCACGGTAATTTAATTTATTTTAATTAATATTAAAT
AAAAATCTATAAAAGTTTGATCTTAAAGGACCTTAATCTTGGTATTAATCACGAAATAAT
ACTTGCACTTTTTCATCCTGATGCAGTAGTATTATTTAATTCTACTTCTAGTCTTTGGGA
GGTTTGCAAGGAATTTGTAGATCCAAATCATAAATTATCTAATGTCCTTAGGCTATTTCA
TCCTATAAAACCTATGCTTGCAGGACGTAAGACTCTCAAAAGTATTGAAGCTATTCTTAA
AGGTAAGTAAAATATTAATTAATTTGAAACATTTAACATCCTTTTTACTTTTTTTTATAC
AGGTAAAAACTATTTAGTTGAAACAAAATTTGATGGGGAGAGAATTTAGTGTCATGTATC
TCCTGAATCTTTAATGTAAAAAAATTTTTTTTATATTTTTTTTGGTTTAACTTAATAATA
AAAATAGGTTTTTCACTAGAAACTCAAACAATTATACAAATATTTATGAAAGAATGATAG
AGCATGTTAGAAGAAGTTTAAAAGATGCTGTTCATAGTTGTATTTTAGATGGAGAAATGG
TTGTAGTAAATAAAATAACAGGATAAAGAGTTTAATTTGGTCTTAATAAAACTGTTGCAA
TGGAAAGAGAGGATGATGAATTATGTATATGTTATAAAATTTTTGACATTTTATATTTGA
AGACTAAAGATAATAAAGAATATGCACTGACAGAATACACATTGCAATATAGAAAAAAAA
TTTTAGAAAATTTAATTGACAATCAATAAGACAGAGTTGAAGTTATTTTTGGTAGAGAAT
ACTCAGATATAAATGACATACTGACTGAATTTAATGAGGCAATACATAGAAACGATGAAG
GTATAGTCATAAAGCAGCTCGATACTCTGTATTACCCAGATGATAGATCTGATAAGTGGA
TTAAAATGAAAGGTGACTACTATGAAGGAATAATAGATACCTTAGATTTGATAGTTATTG
GAGGATATTTTGGTGAAAAGTCTTATAAAATTAATGGCATAGGAGATTGGACAGATCATA
TCACACATTATCTTGTTGCTGTAGCGAAAAAGATTGATCTACAAAACCCCTCTAACTCTA
TACTTGTGCCTTTTGCTAAAGTGGGAGCAGGTTTTACAGCTAGAGACTATGCTGATATAA
AAGCTAGAATGAGAGATCAATGGGTAAGAACTAATCATTCAAATAAAACGCCTTCTTTCA
TCATATAAAACTGGAAACCTGGAGAAAAAGTAAGTTATTTAGAAAAATAATGACTTTTTA
AAAAAATAAAATTTAAGGATAAGCCAGATGCATATATTTTATCTCCTCAAAACTCTCTTA
TTTTAGAGATTAGGGCAACTGAAATTATATAATCTTCTTAATATCCGACCAACTACACCT
TAAGGTATTTATCTATTTTTAAAATACAATTTAAATGAAGTTTTGTAATATCCTAAATTA
AATTTTAGATTTCCGAGATTTGAAAAATTTAGAAGAGATAAAGATTGGTTTGATTGCATG
AAATTTAATGAAATTATAGAAATGACTTAAAATTTAAAGAAAAAAGAATAAAAAGAGAGT
GACAAAGAAGATAATGCAAGCGATGAAGAGTAGGACGAAAATGGAGGAAAATTAAAGAAA
AAAAGAAAAGGGTAAAATGGAGAAGAGATAGAAGTAAATAGACAAGGTAGAAAGCCAAAC
TGGAAGACCAATAAAGTTATGGCTCAATATCTTGATATTGATGTTTCTGATGTCAAAGTA
GAATCAAATATATTTAATAACTTTGTATTTAATATAATTAATTTACCTCATGAAGTATCC
TTGAGTGAGGAAAAGATATTGTTAGAGAAAGCCTAGATTGAAAAAGGTATAGTTGCTAAT
GGTGGTAAAAAAGTATAAAATGATAGCAATCTTGTAACTCATTACATAGCTTCACATTAT
GATTTTAAAGTTTAAGTAATTGGTGATCACTATAAAGTAAATGTTCTATCCTTATAATGG
GTAAAAGACTGTATCAAAAAAAAAACTTTATTAGATTACTCTCCCCGCTACATTATATAT
GGTTAAGATTAATTGCTTGAGAGAAATAAATTGCTTTATGATTAATATGGAGATTCTTAT
TACAAAGATGTTGATGAAGATGAGTTATTGGATATTTTAAAATCTATGAAAATTGATTAA
ATAGAAGAAGAATTCTAGGAGAATGAAGAGTTTGAAGAGGCTGTTAAAGATATTATTTCC
ATGAAAAACCAACTTTTCAAAGAATGTTTTCCGTAAGGATAAACTTATTGCTTTTATAAT
GCAAATGATAAATTGAATTCAGATATAGACTTAAGATATTTAGTTGATCTAATTTAATTT
AGTGGAAATTAAGTTGTATTTGACTTATAGGACGAAATTGATTACATAGTGGCTTTAGAT
TATAGTGAAGCTGAAAACGAAAAAATTATTACCTTCAGAGAAAAAAACAGAAGTATGGAA
GTTATAACTCCTAAAAACTTGTTGAATAATTTTGGAATAGCTCTAGAATGA

>TTHERM_00387050(protein)
MQNYYKWHKIKQEQNQELSVNIKPISSSKMKQSDISTRKKKAQEYNMDFDEFQQEDSKIN
QNSDNFHFGDSADEYGIDSPKMKREKAVKEEDNTFRLEIKKSPILEKTLFSFLVKFYNQV
QQSKKGQRKKFVQRFIDSTFKTNRCPSYTFTILRLIMPHHDKQRLNYGLNYKNLAKVLSE
VFALSEDKRQQLLNYKRPLKDNQQVVGDFGEVVQNVLQAFTQKATLTINDVDRCLDELAQ
PQNRDLASKEKVLRNCLKNATSEEIKWISRLILKDLNLGINHEIILALFHPDAVVLFNST
SSLWEVCKEFVDPNHKLSNVLRLFHPIKPMLAGRKTLKSIEAILKGKNYLVETKFDGERI
QCHVSPESLMFFTRNSNNYTNIYERMIEHVRRSLKDAVHSCILDGEMVVVNKITGQRVQF
GLNKTVAMEREDDELCICYKIFDILYLKTKDNKEYALTEYTLQYRKKILENLIDNQQDRV
EVIFGREYSDINDILTEFNEAIHRNDEGIVIKQLDTLYYPDDRSDKWIKMKGDYYEGIID
TLDLIVIGGYFGEKSYKINGIGDWTDHITHYLVAVAKKIDLQNPSNSILVPFAKVGAGFT
ARDYADIKARMRDQWVRTNHSNKTPSFIIQNWKPGEKDKPDAYILSPQNSLILEIRATEI
IQSSQYPTNYTLRFPRFEKFRRDKDWFDCMKFNEIIEMTQNLKKKEQKESDKEDNASDEE
QDENGGKLKKKRKGQNGEEIEVNRQGRKPNWKTNKVMAQYLDIDVSDVKVESNIFNNFVF
NIINLPHEVSLSEEKILLEKAQIEKGIVANGGKKVQNDSNLVTHYIASHYDFKVQVIGDH
YKVNVLSLQWVKDCIKKKTLLDYSPRYIIYGQDQLLERNKLLYDQYGDSYYKDVDEDELL
DILKSMKIDQIEEEFQENEEFEEAVKDIISMKNQLFKECFPQGQTYCFYNANDKLNSDID
LRYLVDLIQFSGNQVVFDLQDEIDYIVALDYSEAENEKIITFREKNRSMEVITPKNLLNN
FGIALE