Identifiers and Description

Gene Model Identifier

TTHERM_00401980

Standard Name

HRS1 (histidyl-tRNA synthetase 1)

Aliases

PreTt12743 | 43.m00261 | 3713.m00087

Description

HRS1 histidine-tRNA ligase; histidyl-tRNA synthetase family protein

Genome Browser (Macronucleus)

Full Screen View


Genome Browser (Micronucleus)

Full Screen View

Gene Ontology Annotations

Molecular Function

  • glutathionylspermidine synthase activity (IEA) | GO:0008885
  • L-histidine:2-oxoglutarate aminotransferase activity (IEA) | GO:0008110

Biological Process

  • lipoate metabolic process (IEA) | GO:0009106
  • negative regulation of biosynthetic process (IEA) | GO:0009890
  • obsolete activation of MAPKKK activity involved in cell wall organization or biogenesis (IEA) | GO:0000197
  • positive regulation of catabolic process (IEA) | GO:0009896

Domains

  • ( PF00587 ) tRNA synthetase class II core
  • ( TIGR00442 ) histidyl-tRNA synthetase
  • ( TIGR00443 ) ATP phosphoribosyltransferase, regulatory subunit

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_13986.1 9.997093137033517e-262
Description: histidyl-tRNA synthetase (464 aa)
DictyBase DDB_G0269822 3.0008725323024365e-87
Description: mhisS on chromosome: 1 position 3669575 to 3671080
Stentor Coeruleus SteCoe_24979 7.984904245686979e-30
Description: None
Oxytricha Contig9747.0.g58 7.996806159126539e-24
Description: Histidyl-tRNA synthetase
SGD YPR033C 3.998609120989657e-17
Description: HTS1 Cytoplasmic and mitochondrial histidine tRNA synthetase; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence; mutations in human ortholog HARS2 are associated with Perrault syndrome
WormBase WBGene00002001 0.000000000000004001928599951003
Description: locus:hars-1 Histidine--tRNA ligase status:Confirmed UniProt:P34183 protein_id:CAD89746.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences 

>TTHERM_00401980(coding)
ATGTAGAGATTTAGCTCTTTGCAATCTGTTAAGGGAATGAAGGATTTAGTTGGAAATTAG
CTTTTGAAGCATCGATTTATATTTGATTGCGGTGCTAAGGTAATGGAAAAGCATGGGTAC
TAGATGATTGTTTAAAATATTTTAGAGCATAAATAAGTTTTCTCGAGAACTTTAGGAGAT
ACATCTGAAATTATTAATAAAGAAATGTATGGATTTACTGATTAGTCAGGTAAAGAACTT
GTACTTAGACCAGAAGGTACTGCAAGTGTTGTACGTCATATTTTAGAAAATTCAAAGCAC
TTCGAATAGTAGCAGAAATATTATTATTACGGTCCTATGTATAGATATGAGCGCCCTCAA
CTAGGAAGGCAAAGATAATTTTACTAGCTAGGATGTGAATTTTTACATAAAGAGAATCCT
AAAAATAGCTACTTAATAGATGCTGAGATCATTATAGTAGCTCATAAGTTTTTACAAAGG
GTATTGGGCAAACATTCCGAATTTTAAATGGAGATCAATACAATAGGAGATGTTGAAGAC
AGAGTAAAATACAATTCAATTTTAAAAGAATACTATGAAAAAAATATACACAAACTTTCT
GAATTAAGTAAAATGCGCTTAGAAAGAAATAATCCTTTAAGAATATTTGATTCTAAGGAG
GCATAAGATTAAGATTTAATAGCTAATGCTCCTTAATTTTCAGAAAGTATGAAATAAGAA
AGCAAAGAATACTTTAGAAATCTTTTAGAAGTACTAGATTCTCTTAATATTTCTTACAAG
ATAAATCCTTTACTAGTAAGAGGATTAGATTATTACTCACACACTTGCTTTGAAATCAAA
AATGTTGCTCAATAGGGTAAATCTTAAGACACAATCCTGGCAGGTGGCAGATACGATCAT
CTAGCATCAGTTCTTAACTCAAAAGCTACCAACTTAAACGGAGTAGGCTTTGCATGTGGT
ATCGAAAGAATTGGCTTGCTCTTGCAAGACGATGATCCCAAGTTAAAAGAGTTTGAGAAG
AAAAAGATTAAAATAGGAATTGTTCCTGTCCTAGGAAAATAAAATTTAAGTGATGAATTT
GAAAGAAATCTCAAGCTATATTGCGTCAATTTAATGAATTCAATCTCTGATGATTAAATT
GAAGTCTAACTTGTCCTTCATACATCTAAAATGGATAAGTAAATGGAATATTTATTGAAG
AATGAATTCAAATGGGGTATTTTCATTGGCGAAAATGAGGTGAAAGAAAAAAAAGTGAGC
ATAAAAAATTTATTAGATCGCGAAAGTTTTACTATTGAACGTGAGTAGATAAATAATTAC
CAATTTTGA


>TTHERM_00401980(gene)
ATGTAGAGATTTAGCTCTTTGCAATCTGTTAAGGGAATGAAGGATTTAGTTGGAAAGTAA
TAAATATTTATTACTTTTTCCATTTAAAAATTAAACTATTATAAAACTATAAAGTTAGCT
TTTGAAGCATCGATTTATATTTGATTGCGGTGCTAAGGTAATGGAAAAGCATGGGTACTA
GATGATTGTTTAAAATATTTTAGAGCATAAATAAGTTTTCTCGAGAACTTTAGGAGATAC
ATCTGAAATTATTAATAAAGTAAAAAAAACTTATGCTCTCTTATTTTAATTTAGTCAACT
TTAAATATTCATTTTAAGATTTTTATGAGTATTTTCCTTTTTTTTATATTGTTTCTTAAA
GTTGATAAATTTTGGTTGATTTAATAGATAATTCTAGTTAATTTTTTTGAAATCCATTAA
GATTTTATGTTTTTTTATCTAACCAATTTATGATTCATTTTATAAAAGGAAATGTATGGA
TTTACTGATTAGTCAGGTAAAGAACTTGTACTTAGACCAGAAGGTACTGCAAGTGTTGTA
CGTCATATTTTAGAAAATTCAAAGCACTTCGAATAGTAGCAGAAATATTATTATTACGGT
CCTATGTATAGATATGAGCGCCCTCAACTAGGAAGGCAAAGATAATTTTACTAGCTAGGA
TGTGAATTTTTACATAAAGAGAATCCTAAAAATAGCTACTTAATAGATGCTGAGATCATT
ATAGTAGCTCATAAGTTTTTACAAAGGGTATTGGGCAAACATTCCGAATTTTAAATGGAG
ATCAATACAATAGGAGATGTTGAAGACAGAGTAAAATACAATTCAATTTTAAAAGAATAC
TATGAAAAAAATATACACAAACTTTCTGAATTAAGTAAAATGCGCTTAGAAAGAAATAAT
CCTTTAAGAATATTTGATTCTAAGGAGGCATAAGATTAAGATTTAATAGCTAATGCTCCT
TAATTTTCAGAAAGTATGAAATAAGAAAGCAAAGAATACTTTAGAAATCTTTTAGAAGTA
CTAGATTCTCTTAATATTTCTTACAAGATAAATCCTTTACTAGTAAGAGGATTAGATTAT
TACTCACACACTTGCTTTGAAATCAAAAATGTTGCTCAATAGGGTAAATCTTAAGACACA
ATCCTGGCAGGTGGCAGATACGATCATCTAGCATCAGTTCTTAACTCAAAGTATAATTAA
ATAAAATATTTTTAAATTTTAAATACATTTAATAAAAACCCAAATAAAATCATAGTAGAA
AAAAAATTTAATTTGAAACAATTTAAGTAAATTTGTAAAAAATAATTAGAATTTATGATC
AAAGTTATAAATAACATAAGATTTATTTTTTTAATATTTGCTACAAATACATAATAAATA
AATGGTTGAAATAGCATTTCATTTATATATCAAATTTTTTAAAAATACAAACAGTTATTT
TATTTACTATTAAATAAAATTTTATAAATTAGAAACATTAAATAATATTTCAAATAATTT
TAAATGATTTAATCTAATTTAAATATTCATATTTTATTGTTAATGATTTTGGCTTTTATA
TGGTTTAAGATAAAAAAGATATGAAGATTTTATTTATCTATCTACATTAATTTTATTTAG
GATGTTTTTTATTCTTCTACTAGCACTTTTTTTAGCTATAAGTTGAAATTATATAGAATT
TATTTGGATTAACTATATATTCATTTTCTCCATCATTGCATATGTTGGATTCACCAACAC
TAGAGTATTTTTCCATCTATAGCATTATTTCGGTTTGCTATTAGATTTCTATTTATTACG
ACTATTTTAATACAAGATAGAGGAAAAATAGAACAAGTAGCAAATTCTCCTTCTTTATAT
AAGATATTTTGTTCAATATATAATTGTTTTATGTTCACTTTGTTAAACCACATTTATACA
TTTTAAATTTTATTTTAAATTATAGAGCTACCAACTTAAACGGAGTAGGCTTTGCATGTG
GTATCGAAAGAATTGGCTTGCTCTTGCAAGACGATGATCCCAAGTTAAAAGAGTTTGAGA
AGAAAAAGATTAAAATAGGAATTGTTCCTGTCCTAGGAAAATAAAATTTAAGTGATGAAT
TTGAAAGAAATCTCAAGCTATATTGCGTCAATTTAATGAATTCAATCTCTGATGATTAAA
TTGAAGTCTAACTTGTCCTTCATACATCTAAAATGGATAAGTAAATGGAATATTTATTGA
AGGTAATTACTATTGATATATTATTGAAACTAATTATTGAAAGCAAAAATAGGTTTTAGT
TTTTAAGATGAAGCTTATTTGAAATAGAATGATTTTAAATTTAACATTTTTTGTTTAAAA
TAGAATGAATTCAAATGGGGTATTTTCATTGGCGAAAATGAGGTGAAAGAAAAAAAAGTG
AGCATAAAAAATTTATTAGATCGCGAAAGTTTTACTATTGAACGTGAGTAGATAAATAAT
TACCAATTTTGA


>TTHERM_00401980(protein)
MQRFSSLQSVKGMKDLVGNQLLKHRFIFDCGAKVMEKHGYQMIVQNILEHKQVFSRTLGD
TSEIINKEMYGFTDQSGKELVLRPEGTASVVRHILENSKHFEQQQKYYYYGPMYRYERPQ
LGRQRQFYQLGCEFLHKENPKNSYLIDAEIIIVAHKFLQRVLGKHSEFQMEINTIGDVED
RVKYNSILKEYYEKNIHKLSELSKMRLERNNPLRIFDSKEAQDQDLIANAPQFSESMKQE
SKEYFRNLLEVLDSLNISYKINPLLVRGLDYYSHTCFEIKNVAQQGKSQDTILAGGRYDH
LASVLNSKATNLNGVGFACGIERIGLLLQDDDPKLKEFEKKKIKIGIVPVLGKQNLSDEF
ERNLKLYCVNLMNSISDDQIEVQLVLHTSKMDKQMEYLLKNEFKWGIFIGENEVKEKKVS
IKNLLDRESFTIEREQINNYQF