Identifiers and Description

Gene Model Identifier

TTHERM_00444870

Standard Name

CEN4 (CENtrin 4)

Aliases

PreTt03855 | 51.m00221 | 3704.m00077

Description

CEN4 caltractin ICL1d; EF hand family protein- centrin family member; EF-hand calcium-binding protein; also called caltractin; GFP-fusion protein localized to specialized structures of oral apparatus- along deep rootlet- and at contractile vacuole pore

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF00036 ) EF hand
• ( PF07498 ) Rho termination factor, N-terminal domain
• ( PF08730 ) Rad33
• ( TIGR01784 ) conserved hypothetical protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_10867.1	4.9996115996408327e-110
	Description: EF hand family protein (175 aa)
Oxytricha	Contig22557.0.g47	9.004385969422137e-73
	Description: EF-hand domain pair
Stentor Coeruleus	SteCoe_37504	3.6251409191435593e-34
	Description: None
SGD	YOR257W	3.000555717977434e-27
	Description: CDC31 Calcium-binding component of the spindle pole body (SPB) half-bridge, required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation
DictyBase	DDB_G0279407	3.0002687256732656e-20
	Description: calA on chromosome: 3 position 2244074 to 2245039
WormBase	WBGene00000552	1.9999391735788327e-19
	Description: locus:cmd-1 Calmodulin status:Confirmed UniProt:O16305 protein_id:CCD69969.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:15944224: Stemm-Wolf AJ, Morgan G, Giddings TH, White EA, Marchione R, McDonald HB, Winey M (2005) Basal body duplication and maintenance require one member of the Tetrahymena thermophila centrin gene family. Molecular biology of the cell 16(8):3606-19
2. Ref:9163921: Guerrini AM, Ascenzioni F, Gallo T, Donini P (1997) Yeast linear plasmids with T2AG3 telomeres: TEL+CEN antagonism and genetic and molecular stability. FEMS microbiology letters 150(1):165-71
3. Ref:2190243: Ascenzioni F, Guerrini AM, Donini P (1990) Functional telomere formation in yeast using synthetic C4A2 sequences. Plasmid 23(1):16-26

Sequences

>TTHERM_00444870(coding)
ATGAATTCAAAGAAAACTGTTGCTCCTTAAGGTAAAAATTTTGGCGTTGCTAACAAGAAG
TAACCTTAATAAAGACCTGGTTTGACTGAAGATGAAATTGAAGAAATAAGAGAAGCCTTC
AACTTATTCGATACTGAAGGTTCTGGTAAGATTGATCCCAGAGAATTAAAAGCAGCCATG
CAATCGTTGGGTTTTGAAAATAAGAATCCTACTATCTATGGTATGATCGCTGATTTAGAA
AGTTAAGGAACAGAAATTGATTTTGAAGATTTCTTAGATGCTATTACCTCAAAGCTTGGA
GACAAAGAAACTAGAGACGGAATTAACAAAATCTTTGAGTTATTTGATGATGATTAAACT
AAGAGTATTACTTTGAAGAATTTAATGCGTGTTGCTAAGGAATTAGGTGAAACAATGACC
TAAGAAGAATTAGCTGAGATGTTAGAACGTGCCGCTAGCAATAGCAGAGAAATTACCCCT
GAAGATTTCTACAACATCATGGTCAAGAAAACTTTCTGA

>TTHERM_00444870(gene)
ATGAATTCAAAGAAAACTGTTGCTCCTTAAGGTAAAAATTTTGGCGTTGCTAACAAGAAG
TAACCTTAATAAAGACCTGGTTTGACTGAAGATGAAATTGAAGAAATAAGAGAAGCCTTC
AACTTATTCGATACTGAAGGTTCTGGTAAGATTGATCCCAGAGAATTAAAAGCAGCCATG
CAATCGTTGGGTTTTGAAAATAAGAATCCTACTATCTATGGTATGATCGCTGATTTAGAA
AGTTAAGGAACAGAAATTGATTTTGAAGATTTCTTAGATGCTATTACCTCAAAGCTTGGA
GACAAAGAAACTAGAGACGGAATTAACAAAATCTTTGAGTTATTTGATGATGATTAAACT
AAGAGTATTACTTTGAAGAATTTAATGCGTGTTGCTAAGGAATTAGGTGAAACAATGACC
TAAGAAGAATTAGCTGAGATGTTAGAACGTGCCGCTAGCAATAGCAGAGAAATTACCCCT
GAAGATTTCTACAACATCATGGTCAAGAAAACTTTCTGA

>TTHERM_00444870(protein)
MNSKKTVAPQGKNFGVANKKQPQQRPGLTEDEIEEIREAFNLFDTEGSGKIDPRELKAAM
QSLGFENKNPTIYGMIADLESQGTEIDFEDFLDAITSKLGDKETRDGINKIFELFDDDQT
KSITLKNLMRVAKELGETMTQEELAEMLERAASNSREITPEDFYNIMVKKTF