Identifiers and Description

Gene Model Identifier

TTHERM_00455300

Standard Name

APM3 (Adaptor Protein complex Medium subunit 3 )

Aliases

PreTt20259 | 53.m00161 | 3712.m00022 | APM1B

Description

APM1B clathrin adapter protein AP-1 mu subunit

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Molecular Function

• basic amino acid transmembrane transporter activity (IEA) | GO:0015174
• hormone binding (ISS) | GO:0042562 | Ref:16276403
• hormone binding (IEA) | GO:0042562
• quinoprotein glucose dehydrogenase activity (IEA) | GO:0008876

Biological Process

• axial mesodermal cell differentiation (IEA) | GO:0048321
• negative regulation of axial mesodermal cell fate determination (ISS) | GO:0048325 | Ref:16276403
• negative regulation of mesodermal cell fate determination (IEA) | GO:0048335

Domains

• ( PF00928 ) Adaptor complexes medium subunit family
• ( PF01217 ) Clathrin adaptor complex small chain

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_13727.1	9.997093137033517e-262
	Description: adaptor complexes medium subunit protein (440 aa)
Oxytricha	Contig21523.0.g45	3.999622461503957e-161
	Description: Adaptor complexes medium subunit family
DictyBase	DDB_G0289247	2.0000633521090825e-149
	Description: apm1 on chromosome: 5 position 2536641 to 2538194
WormBase	WBGene00000150	2.000893364583308e-148
	Description: locus:apm-1 status:Confirmed UniProt:O01755 protein_id:CCD65442.1
SGD	YPL259C	2.000808864924972e-124
	Description: APM1 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1); binds clathrin; involved in clathrin-dependent Golgi protein sorting
Stentor Coeruleus	SteCoe_31620	4.408531331463226e-71
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16276403: Elde NC, Morgan G, Winey M, Sperling L, Turkewitz AP (2005) Elucidation of clathrin-mediated endocytosis in tetrahymena reveals an evolutionarily convergent recruitment of dynamin. PLoS genetics 1(5):e52

Sequences

>TTHERM_00455300(coding)
ATGTCTGGAATTTCAGGAATATTTATCCTTAATAATAAAGGAAGAGTTATTATTCAAAGA
GTTTATCGTGCTGATTTACAAGTGCATGTAATTGAAACATTTAATAAAAAATTAGTTGAA
TTTGATGAATTCAATCAAAAGCCTATTGTCTAAGATGAGTTTGGAAATACTTACATTTAT
AGAAATCACAACAATTTAACTTTTTTGATCATTACAAGAAGAAATACTAATGTTATGATG
GTTTTTGCCTTCTTGTATTAGTTTATCGAAGTTTTAGTTCATTATTTTAAAGAGCTGGAA
GAAGAATCTGTCAGAGATAATTTTGTAGTAATTTATGAATTATTAGATGAAGTTTTAGAT
AATGGATATCCTCAAATTACTGACTGCAAAAACTTATCTGAATTTATTAAAACAGAAAGT
CATGAGCTAGTTAAAGATTCTTTCTTTGGAGGAAAAGAAAAAAAAGAAGAAAATTTATCA
AAGTATGCAACTATGTCAACAGCAGCTATTTCATGGAGACCTGAAGGAATTAAATATAAA
AAGAATGAAATCTTCTTAGATGTTTATGAAAAGCTAAATATGCTAATTGGTAAAACTGGT
AACGTTATTGAAGCTGAAATCATAGGTAATGTAGTTGCAAATTCTATGCTTTCAGGTATG
CCTGACTGTAAGCTCGGCTTAAATGATAAAGCATATTTTGAAGCTATAGGTAGATCCACA
AATGCAAGAACAATTAACTTTGAAGATATGAAATTCCATTAATGTGTTCGTTTATCTAAA
TTTGAAAATGAAAGGCTCATTACTTTTATTCCTCCTGATGGTGAATTCGAACTGATTTCA
TATAGAATTCCTGTTCAAATTAAGCCTCTCTTCTAAGTGGATGTAATTATTACCCAACCT
AAACCAACTAAAATTGAAATAATGGTAAAAGCCAAGTCTAATTTTAAAGAGAAATCAACA
GCAAATGATGTCGACATATATATACCTGTTCCTGAAGATGTATAGAAACCAGAATTTAAG
TGTGCTTTTGGTAAATCAATCTGGGATTAAGGACGCGAAGCTATCAAATGGAGCTTCAAG
TAATTTGTTGGTCAAAAAGAATATATCATGTAATGCACTTTCAATTTACCCACAGTTGCT
TCTCCTGGTAGAGAAAAATATAAATAAGTACCTATTTCTATTAATTTCGAAATTCCATAT
TACACTGTTAGCGGCTTCTAAGTTAGATATCTTAAAGTTGAAGAGAGAAGTGGCTATAAT
GCACTTCCATGGGTTCGTTATGTAACTAAAAATGGCGATTACTAAATAAGAATGTTTTGA

>TTHERM_00455300(gene)
ATGTCTGGAATTTCAGGAATATTTATCCTTAATAATAAAGGAAGAGTTATTATTCAAAGA
GTTTATCGTGCTGATTTACAAGTGCATGTAATTGAAACATTTAATAAAAAATTAGTTGAA
TTTGATGAATTCAATCAAAAGCCTATTGTCTAAGATGAGTTTGGAAATACTTACATTTAT
AGAAATCACAACAATTTAACTTTTTTGATCATTACAAGAAGAAATACTAATGTTATGATG
GTTTTTGCCTTCTTGTATTAGTTTATCGAAGTTTTAGTTCATTATTTTAAAGAGCTGGAA
GAAGAATCTGTCAGAGATAATTTTGTAGTAATTTATGAATTATTAGATGAAGTTTTAGAT
AATGGATATCCTCAAATTACTGACTGCAAAAACTTATCTGAATTTATTAAAACAGAAAGT
CATGAGCTAGTTAAAGGTAATTAATTTATCTCAAATAGCCTCAAGCTTATTTTACAGAAA
TATTAAAATCAATATTTCAAAAATAGAATTTAATTTGAAAATCATGATTGTGCAAATTTT
GATTTATTGTCACTCATAAAATGGCTTAAATCTTCTAAGCTAATTATTTATTTATATGAG
ATATTATTAATGATGTAAACTAATTAAATCATTTTTCATTTACAAAAATAGATTCTTTCT
TTGGAGGAAAAGAAAAAAAAGAAGAAAATTTATCAAAGTATGCAACTATGTCAACAGCAG
CTATTTCATGGAGACCTGAAGGAATTAAATATAAAAAGAATGAAATCTTCTTAGATGTTT
ATGAAAAGCTAAATATGCTAATTGGTAAAACTGGTAACGTTATTGAAGCTGAAATCATAG
GTAATGTAGTTGCAAATTCTATGCTTTCAGGTATGCCTGACTGTAAGCTCGGCTTAAATG
ATAAAGCATATTTTGAAGCTATAGGTAGATCCACAAATGCAAGAACAATTAACTTTGAAG
ATATGAAATTCCATTAATGTGTTCGTTTATCTAAATTTGAAAATGAAAGGCTCATTACTT
TTATTCCTCCTGATGGTGAATTCGAACTGATTTCATATAGGTAAAATCATTAAATGTCAT
TTAAATTATCTTATTTTAAAAATATAAAGAATTCCTGTTCAAATTAAGCCTCTCTTCTAA
GTGGATGTAATTATTACCCAACCTAAACCAACTAAAATTGAAATAATGGTAAAAGCCAAG
TCTAATTTTAAAGAGAAATCAACAGCAAATGATGTCGACATATATATACCTGTTCCTGAA
GATGTATAGAAACCAGAATTTAAGTGTGCTTTTGGTAAATCAATCTGGGATTAAGGACGC
GAAGCTATCAAATGGAGCTTCAAGTAATTTGTTGGTCAAAAAGAATATATCATGTAATGC
ACTTTCAATTTACCCACAGTTGCTTCTCCTGGTAGAGAAAAATATAAATAAGTACCTATT
TCTATTAATTTCGAAATTCCATATTACACTGTTAGCGGCTTCTAAGTTAGATATCTTAAA
GTTGAAGAGAGAAGTGGCTATAATGCACTTCCATGGGTTCGTTATGTAACTAAAAATGGC
GATTACTAAATAAGAATGTTTTGA

>TTHERM_00455300(protein)
MSGISGIFILNNKGRVIIQRVYRADLQVHVIETFNKKLVEFDEFNQKPIVQDEFGNTYIY
RNHNNLTFLIITRRNTNVMMVFAFLYQFIEVLVHYFKELEEESVRDNFVVIYELLDEVLD
NGYPQITDCKNLSEFIKTESHELVKDSFFGGKEKKEENLSKYATMSTAAISWRPEGIKYK
KNEIFLDVYEKLNMLIGKTGNVIEAEIIGNVVANSMLSGMPDCKLGLNDKAYFEAIGRST
NARTINFEDMKFHQCVRLSKFENERLITFIPPDGEFELISYRIPVQIKPLFQVDVIITQP
KPTKIEIMVKAKSNFKEKSTANDVDIYIPVPEDVQKPEFKCAFGKSIWDQGREAIKWSFK
QFVGQKEYIMQCTFNLPTVASPGREKYKQVPISINFEIPYYTVSGFQVRYLKVEERSGYN
ALPWVRYVTKNGDYQIRMF