Identifiers and Description

Gene Model Identifier

TTHERM_00469230

Standard Name

MPK1 (Mitogen-activated Protein Kinase )

Aliases

PreTt18725 | 55.m00280 | 3710.m00128

Description

MPK1 cyclin-dependent kinase-like Serine/Threonine kinase family protein; Putative ERK1/2 subfamily mitogen-activated protein (MAP) kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase
• ( PF08194 ) DIM protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_13752	0
	Description: None
Tetrahymena borealis	EI9_15672.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (758 aa)
Oxytricha	Contig19712.0.g79	9.997093137033517e-262
	Description: Protein kinase domain
DictyBase	DDB_G0286353	2.9995941501461703e-129
	Description: erkA on chromosome: 4 position 4355028 to 4356796
SGD	YBL016W	5.0008352594020174e-107
	Description: FUS3 Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation
WormBase	WBGene00003401	3.001222955304439e-106
	Description: locus:mpk-1 Mitogen-activated protein kinase mpk-1 status:Confirmed UniProt:P39745 protein_id:CAA87057.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00469230(coding)
ATGCAGCAATAATAATTATAGAATTAATATAATCACGTTAAGTAGATGTAGTAATAATAA
AATTAGCAATAACAAGCACAATAGTAATAGCTGTAACAACAATAGTAGCAATAGTAGTAG
CATTAGTAGGCACAACAGCACCAAGAAAAGCCTCAAAAACCAATTCAAGTACCTCCTGGT
AAGCACAAATTTGATTGTGGGCAGACTATTTTTGTTGTCGATGAGAAATATGAATATATA
AAATAGATCGGATATGGAGCTTACGGTGTGGTTTGCTCAGCAGTAAATAAAGAAAATGGT
TCAAAAGTTGCAATTAAAAAGGTTTAAAATGCTTATGATGATTTGATCGATGCAAAGCGT
ATTGTCAGAGAAATCAAACTTTTAAAATTCTTTGAACACGATAATATTATTTCACTTTTA
GATGTTATTAAGCCTAACGCGCCAGTAGGTGACGAAGATATCTACATGGTATTTGATTTG
ATGGAAACTGATTTGCACCGTGTTATTTATTCTCGTTAAGAACTCAGCGATGAGCATATC
TAATATTTTGTCTATTAAATTCTTCGTGGTCTCTTATACATTCATTCTGCAAATGTTATT
CATCGTGATCTAAAGCCCAGCAATATTTTGCTTAATAAGAACTGTGATCTTAAAATTTGC
GATTTTGGTCTGGCCCGTGGATTCGAAGAGCCTGGTGAAAGCTTGACTGAATACGTAATT
ACTCGTTGGTACCGTGCTCCTGAAGTTATTTTGAATGCTAGTGAGTACAATCAAGCTGTT
GATATTTGGTCAGTTGGTTGCATCACTGCTGAATTATTAGGAAGAACACCCCTTTTCCCA
GGAGAAAATTATCTAGATTAAGTTTAGCGTGTCATAGCAGTTTTAGGAACCCCTACTCAA
GAAGATATGGCTTATATTGGCAATTAAGATGCTATTAAATATATAAAATCTCAACCAAAA
AGAACTAAATAATCATGGTAGAGTCTTTATCCGAAAGCAAATCCACTAGCTCTTGACCTT
TTAAGTAAAATGCTCACTTTCAATCCAGAAAAACGCTATACTGTTAAAGAATGCATCGAA
CATCCTTACTTCGAAGGACTTCATTACCCTGATGAAGAACCTGAGTGTGAGTAACTTGAA
ACATTTATGAAAATTAAGAAGAAAAACAAATTCAAATTCAAAGATTAATAAAAGGAGATA
AATAGATACAAATAATCAAGCAAATAAATAAATAATCAAGCAAATAAGCAAAAGCAAGCA
AGCAAACAAGCAAACATTTATTTATTATTACTATTGTAGTTTTTTAAATTTAGAATTTTT
TCAAACAAGAAGTAATAGTAATTTAAAAAATATAAAATACATTCTCTAAAATCATAGCTT
GACGCTTCATTTATCAACATAACGATTAAAAAAAGGTATGTCATCATAATTTAAAAAAGA
GTACAAATTATTTATGTTATTACTTAAATCCAATATAATAAATAAATATCTCCTTTTATT
TCTTAAACAGTAAAGAAATGTTAATCAAAACGTATAAATATATTTATATATATATATAGT
TATATAGATAGTAAGTTAGATAATCACTTTGTCTTATAATCTAGGCTTCATTTAATATTA
GCACCAAAAATCAATTAGACATTAACTTATTATAATATTTTTGTATAAATATTTTCGACT
TTGAAATTTTAGTTATTTTTAATTTATTTAAACTCTAATTTACTATTTTTTTTTGAAATA
TTTATGACATAAAAAAAAACATGA

>TTHERM_00469230(gene)
ATGCAGCAATAATAATTATAGAATTAATATAATCACGTTAAGTAGATGTAGTAATAATAA
AATTAGCAATAACAAGCACAATAGTAATAGCTGTAACAACAATAGTAGCAATAGTAGTAG
CATTAGTAGGCACAACAGCACCAAGAAAAGCCTCAAAAACCAATTCAAGTACCTCCTGGT
AAGCACAAATTTGATTGTGGGCAGACTATTTTTGTTGTCGATGAGAAATATGAATATATA
AAATAGATCGGATATGGAGCTTACGGTGTGGTTTGCTCAGCAGTAAATAAAGAAAATGGT
TCAAAAGTTGCAATTAAAAAGGTTTAAAATGCTTATGATGATTTGATCGATGCAAAGCGT
ATTGTCAGAGAAATCAAACTTTTAAAATTCTTTGAACACGATAATATTATTTCACTTTTA
GATGTTATTAAGCCTAACGCGCCAGTAGGTGACGAAGATATCTACATGGTATTTGATTTG
ATGGAAACTGATTTGCACCGTGTTATTTATTCTCGTTAAGAACTCAGCGATGAGCATATC
TAATATTTTGTCTATTAAATTCTTCGTGGTCTCTTATACATTCATTCTGCAAATGTTATT
CATCGTGATCTAAAGCCCAGCAATATTTTGCTTAATAAGAACTGTGATCTTAAAATTTGC
GATTTTGGTCTGGCCCGTGGATTCGAAGAGCCTGGTGAAAGCTTGACTGAATACGTAATT
ACTCGTTGGTACCGTGCTCCTGAAGTTATTTTGAATGCTAGTGAGTACAATCAAGCTGTT
GATATTTGGTCAGTTGGTTGCATCACTGCTGAATTATTAGGAAGAACACCCCTTTTCCCA
GGAGAAAATTATCTAGATTAAGTTTAGCGTGTCATAGCAGTTTTAGGAACCCCTACTCAA
GAAGATATGGCTTATATTGGCAATTAAGATGCTATTAAATATATAAAATCTCAACCAAAA
AGAACTAAATAATCATGGTAGAGTCTTTATCCGAAAGCAAATCCACTAGCTCTTGACCTT
TTAAGTAAAATGCTCACTTTCAATCCAGAAAAACGCTATACTGTTAAAGAATGCATCGAA
CATCCTTACTTCGAAGGACTTCATTACCCTGATGAAGAACCTGAGTGTGAGTAAGTTTTT
GATTGGTCTTGGGATAAATTCACACCTACTAAAGAAATATTGTAGAAGATGATCTACTAA
GAAGCTAAATCTTTCCATCCTATTCACTGAAATGCAGGATTACTTTGTACAATCATTATA
AATTTTTAATATTAAAATACTAAATAATAATCATATTCAACCATTCATAAATTTTAAATC
ATTGTAAGCTTTATTCATACTTTAATTCTATAAATAGCTTGAAACATTTATGAAAATTAA
GAAGAAAAACAAATTCAAATTCAAAGATTAATAAAAGGAGATAAATAGATACAAATAATC
AAGCAAATAAATAAATAATCAAGCAAATAAGCAAAAGCAAGCAAGCAAACAAGCAAACAT
TTATTTATTATTACTATTGTAGTTTTTTAAATTTAGAATTTTTTCAAACAAGAAGTAATA
GTAATTTAAAAAATATAAAATACATTCTCTAAAATCATAGCTTGACGCTTCATTTATCAA
CATAACGATTAAAAAAAGGTATGTCATCATAATTTAAAAAAGAGTACAAATTATTTATGT
TATTACTTAAATCCAATATAATAAATAAATATCTCCTTTTATTTCTTAAACAGTAAAGAA
ATGTTAATCAAAACGTATAAATATATTTATATATATATATAGTTATATAGATAGTAAGTT
AGATAATCACTTTGTCTTATAATCTAGGCTTCATTTAATATTAGCACCAAAAATCAATTA
GACATTAACTTATTATAATATTTTTGTATAAATATTTTCGACTTTGAAATTTTAGTTATT
TTTAATTTATTTAAACTCTAATTTACTATTTTTTTTTGAAATATTTATGACATAAAAAAA
AACATGA

>TTHERM_00469230(protein)
MQQQQLQNQYNHVKQMQQQQNQQQQAQQQQLQQQQQQQQQHQQAQQHQEKPQKPIQVPPG
KHKFDCGQTIFVVDEKYEYIKQIGYGAYGVVCSAVNKENGSKVAIKKVQNAYDDLIDAKR
IVREIKLLKFFEHDNIISLLDVIKPNAPVGDEDIYMVFDLMETDLHRVIYSRQELSDEHI
QYFVYQILRGLLYIHSANVIHRDLKPSNILLNKNCDLKICDFGLARGFEEPGESLTEYVI
TRWYRAPEVILNASEYNQAVDIWSVGCITAELLGRTPLFPGENYLDQVQRVIAVLGTPTQ
EDMAYIGNQDAIKYIKSQPKRTKQSWQSLYPKANPLALDLLSKMLTFNPEKRYTVKECIE
HPYFEGLHYPDEEPECEQLETFMKIKKKNKFKFKDQQKEINRYKQSSKQINNQANKQKQA
SKQANIYLLLLLQFFKFRIFSNKKQQQFKKYKIHSLKSQLDASFINITIKKRYVIIIQKR
VQIIYVITQIQYNKQISPFISQTVKKCQSKRINIFIYIYSYIDSKLDNHFVLQSRLHLIL
APKINQTLTYYNIFVQIFSTLKFQLFLIYLNSNLLFFFEIFMTQKKT