Identifiers and Description

Gene Model Identifier

TTHERM_00497960

Standard Name

CCT7 (Chaperonin Containing TCP-1 ortholog 7 )

Aliases

TtCCTeta | PreTt06961 | 62.m00245 | 3715.m00106

Description

CCT7 TCP-1 (CTT or eukaryotic type II) chaperonin family eta subunit; CCT-eta chaperonin subunit; expressed during cilia biogenesis and conjugation

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

Molecular Function

Biological Process

Domains

  • ( PF00118 ) TCP-1/cpn60 chaperonin family
  • ( TIGR02339 ) thermosome, various subunits, archaeal
  • ( TIGR02340 ) T-complex protein 1, alpha subunit
  • ( TIGR02341 ) T-complex protein 1, beta subunit
  • ( TIGR02342 ) T-complex protein 1, delta subunit
  • ( TIGR02343 ) T-complex protein 1, epsilon subunit
  • ( TIGR02344 ) T-complex protein 1, gamma subunit
  • ( TIGR02345 ) T-complex protein 1, eta subunit
  • ( TIGR02346 ) T-complex protein 1, theta subunit
  • ( TIGR02347 ) T-complex protein 1, zeta subunit
  • ( TIGR02348 ) chaperonin GroL

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Stentor Coeruleus SteCoe_6384 0
Description: None
WormBase WBGene00020391 9.997093137033517e-262
Description: locus:cct-7 status:Confirmed UniProt:Q9TZS5 protein_id:CCD74224.1
Tetrahymena borealis EI9_20972.1 9.997093137033517e-262
Description: TCP-1/cpn60 chaperonin family protein (562 aa)
DictyBase DDB_G0291225 9.997093137033517e-262
Description: cct7 on chromosome: 6 position 201367 to 203505
Oxytricha Contig22245.0.g37 9.997093137033517e-262
Description: TCP-1/cpn60 chaperonin family
SGD YJL111W 9.997093137033517e-262
Description: CCT7 Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo; mutant has increased aneuploidy tolerance

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:14567989: Seixas C, Casalou C, Melo LV, Nolasco S, Brogueira P, Soares H (2003) Subunits of the chaperonin CCT are associated with Tetrahymena microtubule structures and are involved in cilia biogenesis. Experimental cell research 290(2):303-21
  2. Ref:11718895: Casalou C, Cyrne L, Rosa MR, Soares H (2001) Microtubule cytoskeleton perturbation induced by taxol and colchicine affects chaperonin containing TCP-1 (CCT) subunit gene expression in Tetrahymena cells. Biochimica et biophysica acta 1522(1):9-21
  3. Ref:10524223: Domingues C, Soares H, Rodrigues-Pousada C, Cyrne L (1999) Structure of Tetrahymena CCT theta gene and its expression under colchicine treatment. Biochimica et biophysica acta 1446(3):443-9
  4. Ref:9819444: Won KA, Schumacher RJ, Farr GW, Horwich AL, Reed SI (1998) Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT. Molecular and cellular biology 18(12):7584-9
  5. Ref:9337846: Soares H, Cyrne L, Casalou C, Ehmann B, Rodrigues-Pousada C (1997) The third member of the Tetrahymena CCT subunit gene family, TpCCT alpha, encodes a component of the hetero-oligomeric chaperonin complex. The Biochemical journal 326 ( Pt 1)( ):21-9
  6. Ref:8925913: Cyrne L, Guerreiro P, Cardoso AC, Rodrigues-Pousada C, Soares H (1996) The Tetrahymena chaperonin subunit CCT eta gene is coexpressed with CCT gamma gene during cilia biogenesis and cell sexual reproduction. FEBS letters 383(3):277-83
  7. Ref:8573069: Walkley NA, Demaine AG, Malik AN (1996) Cloning, structure and mRNA expression of human Cctg, which encodes the chaperonin subunit CCT gamma. The Biochemical journal 313 ( Pt 2)( ):381-9
  8. Ref:7961900: Soares H, Penque D, Mouta C, Rodrigues-Pousada C (1994) A Tetrahymena orthologue of the mouse chaperonin subunit CCT gamma and its coexpression with tubulin during cilia recovery. The Journal of biological chemistry 269(46):29299-307

Sequences 

>TTHERM_00497960(coding)
ATGAGTTATCTTTTGCAACCTACCATTTTGCTCTTGAAGGACGGTACTGATACTTCCTAA
GGAAAGGCTTAAATTGTTTCCAACATTAATGCTGTCTAATCTATTGTAGAAATCGTTAAG
ACCACTTTAGGTCCCCGTGGTATGGATAAATTGATTGAAGGTGGAATGAAGGGAGCCACT
ATTTCCAATGATGGTGCTACTATTTTAAACTTATTAGATATTGTTCACCCTGCTGCTAAG
ACTCTTGTTGATATTGCTAAGGCTTAAGACGATGAAGTTGGTGATGGTACCACTTCTGTC
TGCCTTTTGGCTGGTGAATTATTGAAGGAATCTAAGTACTTCATCGAAGAAGGTATGCAC
CCATAAATTATCACTAAGGGTTACAAGGAAGCCCTCAAGTTAGCTCTTTAATTCTTACAC
GAAAATGCTCACTCTGTAGCTGATAAGAACGAAACTGAAAAGAGAGAAATGCTCATTAAG
TGCGCTTAAACCTCTTTAAACTCCAAATTATTAGCTCATTACAAGGAATTCTTCTCTGAG
TTAGTTGTTTAAGCCGTTGAAACTCTTGAAACTAATCTCCTCGACAAAGACCTTATCGGT
ATCAAGATGGTCACCGGTGGTTCAGTCACTGATTCTTTCTTGGTTAGTGGTGTCGCTTTC
AAGAAAACCTTCTCTTATGCAGGTTTTGAACAACAACCCAAAAAGTTCAATAACCCTAAG
ATTTGCTTACTTAACATCGAATTAGAATTAAAGGCTGAAAAGGAAAATGCTGAAATTAGA
ATTGAAAATCCTGATGATTACAAGTCAATTGTTGATGCTGAATGGGAGTTGATTTATGAA
AAGTTAAGAAAGATTGTTGAATCTGGTGCTAACATTGTTCTCTCCAAGCTTCCTATTGGT
GATTTGGCCACTCAATACTTCGCTGATCGTAACATTTTCTGTGCTGGTCGTGTTGATGCT
GAAGATATGAAGAGAGTCCAAAAATCTACTGGTGCCATCGTTCAAACCACTGTCAATGGT
TTGACTGAAGATGTCTTAGGTACTTGCAACCAATTCGAAGAAGTTTAAATCGGTGCTGAA
AGATATAACCTCTTCAAGGATTGCCCTCACTCTAAGAGTGCTACCATCATTTTAAGAGGT
GGTGCTGAATAATTCATTGCTGAAGCTGAACGTTCTCTTAATGATGCAATCATGATCGTC
AGAAGATGCATGAAGGCCAATAAAATCGTTCCTGGTGGTGGTGCCATCGAATTAGAAATC
TCTCGTCTTCTCCGTTTACACTCCAGAAAGACTGAAGGAAAGATCTAATTAGTTATTAAT
GCTTTTGCTAAGGCTCTTGAAGTCATTCCCAGAACTATTGCTGATAATGCTGGTCACGAC
TCCATTCAAGTTCTTAATAAACTCCGTCAAAAGCATGCTATTGAAACCGAACAATCTAGA
AACTTCGGTGTTGATATTAATGCTGCTGATGGTATTGGCAATAACTACGAAAATTTTGTT
TGGGAACCTATCGTTGTCAGAAAAAATGCTTTGTCTGCTGCCACTGAAGCTGCTTGCACT
ATTTTAAGTATTGATGAAACTGTTAGAAATCCCAAGAGTGAACAACCTAAGGCTCCCCCT
GGTGGACTCAGAAGAGGTGGTCCTCAAGGAATGGCTGGTTTGGCTAAAAATGCTAAGCTC
GGAAAGTGA


>TTHERM_00497960(gene)
ATGAGTTATCTTTTGGTATTTATTTTTTCTTTTTACTTAATTCTTAACAGCAGAAATATT
TTACTACAAACCAATGCGCTTACTTTTGTCCAATATTTTGCCTTAGTTAATTTGAAATCC
CATAAAATGCTTCTCCTTGCGCCCATAAACAGCAAATTTTACATGACCTTCAAATAGATT
ATTATTATTATTACCATTTAATACATTCGATTATAAGATTGTATTAACATATAGACTGTT
TATGGCACTTATAGTAGCAAATAGTTTAAATATTGAAGCTTATATCATGATGATTTCATA
TGATTTATTTGCTATTATCTGCACAAATAATGCTTTGCTTTGATTTTAATTAACACTTTT
TAACTTTTATACTATAGCAACCTACCATTTTGCTCTTGAAGGACGGTACTGATACTTCCT
AAGGAAAGGCTTAAATTGTTTCCAACATTAATGCTGTCTAATCTATTGTAGAAATCGTTA
AGACCACTTTAGGTAAATAAATTTAGAATTTTAAAAAACAATTTATACAAAAGCTTAGCA
AATCTCAGCAATATAATCTTATTCAAGCAACTTATGAAAAAGGATATAAAAAAAGCAATT
GTTTGCTTAAATTGTTATTGTTATTAAGCAATATTCAAATAGGATACTTAAACCTAAATA
AAATTTTTTTATTTTAAAGAAATAGAAATGTTATAAAGCAATTTTACTTTAATTTTAAAA
TGTTTGAATAAAATTTGAAAAATAAACGATCAACCCACCAAGCATCGAACAAAATATATC
TTCTTCATTGATTATAAACAAAAGCACATAAAATAAAGATTATTAGATTTGTTAAATTTC
ATTCGACTCAAATTATATTCTAACCATCATTTTAATTTTTATAGGTCCCCGTGGTATGGA
TAAATTGATTGAAGGTGGAATGAAGGGAGCCACTATTTCCAATGATGGTGCTACTATTTT
AAACTTATTAGATATTGTTCACCCTGCTGCTAAGACTCTTGTTGATATTGCTAAGGCTTA
AGACGATGAAGTTGGTGATGGTACCACTTCTGTCTGCCTTTTGGCTGGTGAATTATTGAA
GGAATCTAAGTACTTCATCGAAGAAGGTATGCACCCATAAATTATCACTAAGGGTTACAA
GGAAGCCCTCAAGTTAGCTCTTTAATTCTTACACGAAAATGCTCACTCTGTAGCTGATAA
GAACGAAACGTAATTATTTATAAAGATATACTGTTATATAATCTAAATTATTATAATTTT
ACATTAGTGAAAAGAGAGAAATGCTCATTAAGTGCGCTTAAACCTCTTTAAACTCCAAAT
TATTAGCTCATTACAAGGAATTCTTCTCTGAGTTAGTTGTTTAAGCCGTTGAAACTCTTG
AAACTAATCTCCTCGACAAAGACCTTATCGGTATCAAGATGGTCACCGGTGGTTCAGTCA
CTGTAAGATTTTATTTTTTAAAATTCAAAATATTCAAAAAGGAAATTATCTAAATATGTG
CCCAGCTAGCTAGCTAGCTACCTAAATTATTAACATTTTTTAAAATTTTATTTTCATTAA
TAAATAGGATTCTTTCTTGGTTAGTGGTGTCGCTTTCAAGAAAACCTTCTCTTATGCAGG
TTTTGAACAACAACCCAAAAAGTTCAATAACCCTAAGATTTGCTTACTTAACATCGAATT
AGAATTAAAGGCTGAAAAGGAAAATGCTGAAATTAGAATTGAAAATCCTGATGATTACAA
GTCAATTGTTGATGCTGAATGGGAGTTGATTTATGAAAAGTTAAGAAAGATTGTTGAATC
TGGTGCTAACATTGTTCTCTCCAAGCTTCCTATTGGTGATTTGGCCACTCAATACTTCGC
TGATCGTAACATTTTCTGTGCTGGTCGTGTTGATGCTGAAGATATGAAGAGAGTCCAAAA
ATCTACTGGTGCCATCGTTCAAACCACTGTCAATGGTTTGACTGAAGATGTCTTAGGTAC
TTGCAACCAATTCGAAGAAGTTTAAATCGGTGCTGAAAGATATAACCTCTTCAAGGATTG
CCCTCACTCTAAGAGTGCTACCATCATTTTAAGAGGTGGTGCTGAATAATTCATTGCTGA
AGCTGAACGTTCTCTTAATGATGCAATCATGATCGTCAGAAGATGCATGAAGGCCAATAA
AATCGTTCCTGGTGGTGGTGCCATCGAATTAGAAATCTCTCGTCTTCTCCGTTTACACTC
CAGAAAGACTGAAGGAAAGATCTAATTAGTTATTAATGCTTTTGCTAAGGCTCTTGAAGT
CATTCCCAGAACTATTGCTGATAATGCTGGTCACGACTCCATTCAAGTTCTTAATAAACT
CCGTCAAAAGCATGCTATTGAAACCGAACAATCTAGAAACTTCGGTGTTGATATTAATGC
TGCTGATGGTATTGGCAATAACTACGAAAATTTTGTTTGGGAACCTATCGTTGTCAGAAA
AAATGCTTTGTCTGCTGCCACTGAAGTAAACATTTATTTACAAAGTTCAATCATATTTAT
TAAATTTATAATTTTACAAATTAGGCTGCTTGCACTATTTTAAGTATTGATGAAACTGTT
AGAAATCCCAAGAGTGAACAACCTAAGGCTCCCCCTGGTGGACTCAGAAGAGGTGGTCCT
CAAGGAATGGCTGGTTTGGCTAAAAATGCTAAGCTCGGAAAGTGA


>TTHERM_00497960(protein)
MSYLLQPTILLLKDGTDTSQGKAQIVSNINAVQSIVEIVKTTLGPRGMDKLIEGGMKGAT
ISNDGATILNLLDIVHPAAKTLVDIAKAQDDEVGDGTTSVCLLAGELLKESKYFIEEGMH
PQIITKGYKEALKLALQFLHENAHSVADKNETEKREMLIKCAQTSLNSKLLAHYKEFFSE
LVVQAVETLETNLLDKDLIGIKMVTGGSVTDSFLVSGVAFKKTFSYAGFEQQPKKFNNPK
ICLLNIELELKAEKENAEIRIENPDDYKSIVDAEWELIYEKLRKIVESGANIVLSKLPIG
DLATQYFADRNIFCAGRVDAEDMKRVQKSTGAIVQTTVNGLTEDVLGTCNQFEEVQIGAE
RYNLFKDCPHSKSATIILRGGAEQFIAEAERSLNDAIMIVRRCMKANKIVPGGGAIELEI
SRLLRLHSRKTEGKIQLVINAFAKALEVIPRTIADNAGHDSIQVLNKLRQKHAIETEQSR
NFGVDINAADGIGNNYENFVWEPIVVRKNALSAATEAACTILSIDETVRNPKSEQPKAPP
GGLRRGGPQGMAGLAKNAKLGK