Identifiers and Description

Gene Model Identifier

TTHERM_00499420

Standard Name

TGP1 (Tetrahymena G-DNA binding Protein )

Aliases

PreTt07985 | 63.m00163 | 3716.m00017

Description

TGP1 G-quartet DNA-binding protein TGP1; G-quartet DNA binding protein; shows preference for binding parallel G-DNAs; activity localized predominantly in the nuclear fraction; knockout strain shows increased occurrence of extra micronuclei; not essential for growth

Genome Browser (Macronucleus)

Full Screen View


Genome Browser (Micronucleus)

Full Screen View

Gene Ontology Annotations

Molecular Function

Biological Process

Domains

  • ( PF04702 ) Vicilin N terminal region
  • ( PF08648 ) Protein of unknown function (DUF1777)

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_09690.1 1.0000509032773212e-171
Description: hypothetical protein (730 aa)

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:10908364: Lu Q, Henderson E (2000) Two Tetrahymena G-DNA-binding proteins, TGP1 and TGP3, share novel motifs and may play a role in micronuclear division. Nucleic acids research 28(15):2993-3001
  2. Ref:9512530: Lu Q, Schierer T, Kang SG, Henderson E (1998) Purification, characterization and molecular cloning of TGP1, a novel G-DNA binding protein from Tetrahymena thermophila. Nucleic acids research 26(7):1613-20
  3. Ref:7509637: Schierer T, Henderson E (1994) A protein from Tetrahymena thermophila that specifically binds parallel-stranded G4-DNA. Biochemistry 33(8):2240-6

Sequences 

>TTHERM_00499420(coding)
ATGACTGATCAAGGTGTCGCTAAAGAACAATACATTACCGTCGGTAGTTTGAAGGAAATT
GCAGATCCCGTCAAGAAATTCCTTAGAAAGGGAAACAGAAAGGGTAGAAATTAGAAGGAA
TTAAAGTTCAGAGCTAAGGTTGTTAACCAATAACTTGCTGACGAAACTGGCTCTATCAAC
TTCACTACTGAAGGTGTTGCCGTAAATAACAACCAAACTTATGAATTCACTGGTTCCTTG
AAGGTTGTCGACTATAAGCTCAACTTAGCTGTTACCTCTGCTACTCCTGCTAAAGATTAA
ATTGCTAATCTTGGTTCTGAATAACTCAGCAAAGCTGATATTGATCAACACTCAGGAAAG
CATATCGTTTTGATCAAGGATCTCATTAATCTTAGAATCGGTCAATCTTTCTTCGCTAGA
CCTAGAGATATTGTTCACAATAACGAATAAAGAAGAATGACAGCTACCTTAGCCGATAAC
ACTGCTGCTATCCAAGCTGAAATTAGTGTTAACAAGAAATCAATCACTTAAGAAGTACTT
GAATCCTTAAACTCTGATAAGGTCTACCTTTTCAGTGATGTTGTTCTCAACTTCAATGAA
AGTAACAAGTTAGTTGCCAGATTCAACTACAGATCAAACATTGTTGAAGCTAATGACCGT
TAGATCTAACAATTATCAAATAACAACTTGAGCGCCAAAGAATACTCAGATGAAACTGAA
AAGAAGGCTCTTACTGATGTCCTCTAAATCCATGAAAAGAAGGAAAGAGTTCACAAATAG
TAAAATAAGAATAAAAATACAAGAAATGCTCACAAGAATCACAACAGATAAAGACCAAAT
TTATAAGAAACTGAACCCGTAAAAATTAGCGGTCTCTAATAATGGAACAATAACTAGACA
GTTATTGGCAAGATTGTCTCTCTCCGCACTGAAGATAAGTCTTTACCAGCTAAGCAAGAC
GGTACCTCAACTACCATGGTCTACCTTAAGGGAACTATTGGTGACGAAACAGGTGTAATT
GATTTCGATATGGCTGAAAAAAGAGATTGCCCTCGTTTCAAAGAAAATGATGTCGTTAAA
TTCACCTCTGTAATGAACAAAGGTAGATAAAGCGCTGAAGGAAAAGTCGGTGGTCACTAC
ATCGAAGTTAAGAAATTCGGTCAATATATTATCCTTTCAGATCATAATATTAACAATGTA
AATTTAAACAATAACTTGTCTAATTTAGAACTCACCGCTCGTCCCAAGAATCCCAACCCA
AGATTCATCAAGGGAGAATTTGTTGGTGTAAAGGAAGAAGAAAAAGATGGAAACATCTAA
TATACTTACACTGTCAGAAGTAAAGAAGGTGAAGAACAATCTATCACTATTAGAAACAAA
ATTACTACACTTAAAGTTGGTGAAATTCACAAAATCGATAGAGAAAGAAAAAGATCAAGT
AGCAGACCTAATCATCAAGGTGGTTAAAGGGGAAATAGATCTCATTCTTAAAATAACAGA
AACCAAAGAAATAGAGATAAGCACCACAATAGCTAAAACAATTAACCCAATAAATACAAC
AAAAACACTTCCGTCTAAAACAATAACAACAACAAAAACTAATAAAGATCTTAATCACAA
AACCAAAGACCTCCTAGAAACTATGATAACAGACAAGGAGGTGAAAATAGAAATAATAGA
TAAAGAAATGAAAATAATAGAAATAATTTCAATGGCAATGGTCATAGAGTCAATAACCAA
AACAATCAAAGAAATAGAAATAGCTCATATCCTAGAAATAATAACTATGATCATCATCAT
AATTAATAAACCGATATTTCTGGCTTAGAACCTGGTAAGAGAGGTCAAAATGTAACTGGT
TAGGTGATTGAAGTTTCTGAATTCTCCAAGTAGATCAATGATAAAACTTTACACTTTGTC
AAGGGTAGAATTGCTGATGAAAATGCTAATATTAGATTTGATATCAAGAAACCTTAAAAC
TTAGAAATTAAGGTTGGTGAAGTCTATAATTTCAAGGACGTTAACAACAAAGTTGATGAT
AATGGTTACCACTATATTGACCTCAATAGATTTGGCAGAGTTTTCCCTTCTCATAAAAAA
TTCTAAAGCATTAATGATAAAAGAAATTGTGATGCTGATCGTTCATCAATTGAATACGTC
AAAAAAACTGTCCCTAACTGA


>TTHERM_00499420(gene)
ATGACTGATCAAGGTGTCGCTAAAGAACAATGTATAATTTTAAATGTCTATTGATGATTA
AATTCATTATAAATTTAATCTTCTTACCATTCAAAATTTATTAATTTGTCTTTGTTTTTA
CAAAAAGACATTACCGTCGGTAGTTTGAAGGAAATTGCAGATCCCGTCAAGAAATTCCTT
AGAAAGGGAAACAGAAAGGGTAGAAATTAGAAGGAATTAAAGTTCAGAGCTAAGGTATGA
AATTAAATTAACATTCTCCCTTAACTTGAAAATACCATTTTTACAGAGTGATTAAAAATC
TGCCTATTTATAAATCAATAAAGTTGATTTTAAAGCTGTATTGGTAGGTCTAGCATAGGC
TGGACATTATCAAATATTTATTTTTTAAGCTTTTACATTCCAAGTTAATTATTCTAAATT
ATTTAATATATTCAATAGGTTGTTAACCAATAACTTGCTGACGAAACTGGCTCTATCAAC
TTCACTACTGAAGGTAATTTCAAAAATGAATATTGTATATAAAATTAATTTTATATATTT
TTATAATTTATAGGTGTTGCCGTAAATAACAACCAAACTTATGAATTCACTGGTTCCTTG
AAGGTTGTCGACTATAAGCTCAACTTAGCTGTTACCTCTGCTACTCCTGCTAAAGATTAA
GTACGATTGTTTGATAAAATAAGCTAATTTTTGAAAATTAAATAAAATTTATTAGATTGC
TAATCTTGGTTCTGAATAACTCAGCAAAGCTGATATTGATCAACACTCAGGAAAGCATAT
CGTTTTGATCAAGGATCTCATTAATCTTAGAATCGGTCAATCTTTCTTCGCTAGAGTAAT
TTTTAAAATAGTTTGTAGATTTTATATTAATATTTATCATTTTTTATAATTTTAATCTTA
AAGCCTAGAGATATTGTTCACAATAACGAATAAAGAAGAATGACAGCTACCTTAGCCGAT
AACACTGCTGCTATCCAAGCTGAAATTAGTGTTAACAAGAAATGTAAACAATAAAATTTA
TTTTAACTAGATATATAGAAAGGCAAAATATTATTGCATCATGAAAAAAGTTAGCATTTG
TAGAGTAAAAGGATATAGATAAATAAACAAATCTATACATATATAGTTAGCCATAAGTAT
TAGAAGTTTTAAATTAATTTTTCAATAAATATATCAAATAGATACTTTTGTTTAGGAAAA
ATAAAGTATATTGTGGCTATCATTATAAGAATTAAATAAATCAAATTAATTATTTGTTTA
GACATTTTAAATCTAAATGAATAAATTTATTACAAGTTAATAAATACCCTTTTTTAATTA
AAGCATCTTATAAAAGTTAAAGAATAAATAAACATTTGCAAATTTATTTATTTATTTACT
TTAAACTAAATTATTAAATCACAAAGAGATTATTTAAATGATAATTTATTCTTATTTTTA
AAATCAAATCACATCTCCAATTTTGCGCCTTAATATCTTTCAACACTAATTCAAATTTGG
GTTAAATTAATTTTAATTAATATCTATTTATTGATAAATAAATAGCAATCACTTAAGAAG
TACTTGAATCCTTAAACTCTGATAAGGTCTACCTTTTCAGTGATGTTGTTCTCAACTTCA
ATGAAAGTAACAAGTTAGTTGCCAGATTCAACTACAGATCAAACATTGTTGAAGCTAATG
ACCGTTAGATCTAACAATTATCAAATAACAACTTGAGCGCCAAAGAATACTCAGATGAAA
CTGAAAAGAAGGCTCTTACTGATGTCCTCTAAATCCATGAAAAGAAGGAAAGAGTTCACA
AATAGTAAAATAAGAATAAAAATACAAGAAATGCTCACAAGAATCACAACAGATAAAGAC
CAAATTTATAAGAAACTGAACCCGTAAAAATTAGCGGTCTCTAATAATGGAACAATAACT
AGACAGTTATTGGCAAGGTAATAGTTTAACTATTCTAAATATTTTTTTTATTTTAAAATA
TATTAAAAATGTAGATTGTCTCTCTCCGCACTGAAGATAAGTCTTTACCAGCTAAGCAAG
ACGGTACCTCAACTACCATGGTCTACCTTAAGGGAACTATTGGTGACGAAACAGGTGTAA
TTGATTTCGATATGGCTGAAAAAAGAGATTGCCCTCGTTTCAAAGAAAATGATGTCGTTA
AATTCACCTCTGTAATGAACAAAGGTAGATAAAGCGCTGAAGGAAAAGTCGGTGGTCACT
ACATCGAAGTTAAGAAATTCGGTCAATATATTATCCTTTCAGATGTAATCACTTTAAATA
ATTTTCATTTAGGAATATCACTAAATAATTTATATTATTAATAAAGCATAATATTAACAA
TGTAAATTTAAACAATAACTTGTCTAATTTAGAACTCACCGCTCGTCCCAAGAATCCCAA
CCCAAGATTCATCAAGGGAGAAGTAAAAGATTATTTTTCTTAAAATTTTTAATATTCTTT
ATAATAAAGATGAATTAAAATTAAATATCAATTTTATTAGTTTGTTGGTGTAAAGGAAGA
AGAAAAAGATGGAAACATCTAATATACTTACACTGTCAGAAGTAAAGAAGGTGAAGAACA
ATCTATCACTATTAGAAACAAAATTACTACACTTAAAGTTGGTGAAATTCACAAAATCGA
TAGAGAAAGAAAAAGAGTAAATAATTTATTATAACAAATTAAAACATTTTTGTTAATTTT
TATTCTATTTTAGTCAAGTAGCAGACCTAATCATCAAGGTGGTTAAAGGGGAAATAGATC
TCATTCTTAAAATAACAGTAATTCCAAACTAATTATTAATAAAAGTATTTATCTTAGCAT
TTTTTACTTAAATAATAAAAGGAAACCAAAGAAATAGAGATAAGCACCACAATAGCTAAA
ACAATTAACCCAATAAATACAACAAAAACACTTCCGTCTAAAACAATAACAACAACAAAA
ACTAATAAAGATCTTAATCACAAAACCAAAGACCTCCTAGAAACTATGATAACAGACAAG
GAGGTGAAAATAGAAATAATAGATAAAGAAATGAAAATAATAGAAATAATTTCAATGGCA
ATGGTCATAGAGTCAATAACCAAAACAATCAAAGAAATAGAAATAGCTCATATCCTAGAA
ATAATAACTATGATCATCATCATAATTAATAAACCGATATTTCTGGCTTAGAACCTGGTA
AGAGAGGTCAAAATGTAACTGGTTAGGTAAAGATAAATTTAAAATTAAATAAAAAAATGA
TATATCTAAATAACTATAATTAGGTGATTGAAGTTTCTGAATTCTCCAAGTAGATCAATG
ATAAAACTTTACACTTTGTCAAGGGTAGAATTGCTGATGAAAATGCTAATATTAGATTTG
ATATCAAGAAACCTTAAAACTTAGAAATTAAGGTTGGTGAAGTCTATAATTTCAAGGACG
TTAACAACAAAGTTGATGATAATGGTTACCACTATATTGACCTCAATAGATTTGGCAGAG
TTTTCCCTTCTCATAAAGTAAATAATTATTTTTAAAAATATTTTATTCATATAATTATTT
GTTAAAAAATTAGAAATTCTAAAGCATTAATGATAAAAGAAATTGTGATGCTGATCGTTC
ATCAATTGAATACGTCAAAAAAACTGTCCCTAACTGA


>TTHERM_00499420(protein)
MTDQGVAKEQYITVGSLKEIADPVKKFLRKGNRKGRNQKELKFRAKVVNQQLADETGSIN
FTTEGVAVNNNQTYEFTGSLKVVDYKLNLAVTSATPAKDQIANLGSEQLSKADIDQHSGK
HIVLIKDLINLRIGQSFFARPRDIVHNNEQRRMTATLADNTAAIQAEISVNKKSITQEVL
ESLNSDKVYLFSDVVLNFNESNKLVARFNYRSNIVEANDRQIQQLSNNNLSAKEYSDETE
KKALTDVLQIHEKKERVHKQQNKNKNTRNAHKNHNRQRPNLQETEPVKISGLQQWNNNQT
VIGKIVSLRTEDKSLPAKQDGTSTTMVYLKGTIGDETGVIDFDMAEKRDCPRFKENDVVK
FTSVMNKGRQSAEGKVGGHYIEVKKFGQYIILSDHNINNVNLNNNLSNLELTARPKNPNP
RFIKGEFVGVKEEEKDGNIQYTYTVRSKEGEEQSITIRNKITTLKVGEIHKIDRERKRSS
SRPNHQGGQRGNRSHSQNNRNQRNRDKHHNSQNNQPNKYNKNTSVQNNNNNKNQQRSQSQ
NQRPPRNYDNRQGGENRNNRQRNENNRNNFNGNGHRVNNQNNQRNRNSSYPRNNNYDHHH
NQQTDISGLEPGKRGQNVTGQVIEVSEFSKQINDKTLHFVKGRIADENANIRFDIKKPQN
LEIKVGEVYNFKDVNNKVDDNGYHYIDLNRFGRVFPSHKKFQSINDKRNCDADRSSIEYV
KKTVPN