Identifiers and Description

Gene Model Identifier

TTHERM_00516370

Standard Name

EFR1 (Elongation Factor 2 Related 1)

Aliases

PreTt10729 | 64.m00209 | 3723.m00065

Description

EFR1 translation elongation factor EF-2 subunit; Elongation factor 2 related protein; expressed only during conjugation- significant amino acid identity to EF-2 from other eukaryotes but with differences at some residues that are typically post-translational regulation sites

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

Molecular Function

  • glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity (IEA) | GO:0008886

Biological Process

Domains

  • ( PF00009 ) Elongation factor Tu GTP binding
  • ( PF00679 ) Elongation factor G C-terminus
  • ( PF01926 ) GTPase of unknown function
  • ( PF03144 ) Elongation factor Tu domain 2
  • ( PF03764 ) Elongation factor G, domain IV
  • ( PF08477 ) Miro-like protein
  • ( TIGR00231 ) small GTP-binding protein domain
  • ( TIGR00475 ) selenocysteine-specific translation elongation factor
  • ( TIGR00483 ) translation elongation factor EF-1, subunit
  • ( TIGR00484 ) translation elongation factor G
  • ( TIGR00485 ) translation elongation factor Tu
  • ( TIGR00490 ) translation elongation factor aEF-2
  • ( TIGR00503 ) peptide chain release factor 3
  • ( TIGR01393 ) GTP-binding protein LepA
  • ( TIGR01394 ) GTP-binding protein TypA/BipA
  • ( TIGR02034 ) sulfate adenylyltransferase, large subunit

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Stentor Coeruleus SteCoe_7852 0
Description: None
WormBase WBGene00001167 9.997093137033517e-262
Description: locus:eef-2 Elongation factor 2 status:Confirmed UniProt:P29691 protein_id:CAB02985.1
Tetrahymena borealis EI9_08465.1 9.997093137033517e-262
Description: elongation factor G, domain IV family protein (842 aa)
DictyBase DDB_G0287685 9.997093137033517e-262
Description: cinC on chromosome: 5 position 689907 to 692602
Oxytricha Contig22552.0.g51 9.997093137033517e-262
Description: Elongation factor Tu GTP binding domain
SGD YOR133W 9.997093137033517e-262
Description: EFT1 Elongation factor 2 (EF-2), also encoded by EFT2; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:14729267: Malavé TM, Forney JD (2004) Identification of a developmentally regulated translation elongation factor 2 in Tetrahymena thermophila. Gene 326( ):97-105
  2. Ref:12673598: Ueno H, Gonda K, Takeda T, Numata O (2003) Identification of elongation factor-1alpha as a Ca2+/calmodulin-binding protein in Tetrahymena cilia. Cell motility and the cytoskeleton 55(1):51-60
  3. Ref:11129794: Gonda K, Komatsu M, Numata O (2000) Calmodulin and Ca2+/calmodulin-binding proteins are involved in Tetrahymena thermophila phagocytosis. Cell structure and function 25(4):243-51
  4. Ref:10731666: Numata O, Kurasawa Y, Gonda K, Watanabe Y (2000) Tetrahymena elongation factor-1 alpha is localized with calmodulin in the division furrow. Journal of biochemistry 127(1):51-6
  5. Ref:10816251: Numata O, Gonda K, Watanabe A, Kurasawa Y (2000) Cytokinesis in Tetrahymena: determination of division plane and organization of contractile ring. Microscopy research and technique 49(2):127-35
  6. Ref:8743583: Kurasawa Y, Hanyu K, Watanabe Y, Numata O (1996) F-actin bundling activity of Tetrahymena elongation factor 1 alpha is regulated by Ca2+/calmodulin. Journal of biochemistry 119(4):791-8
  7. Ref:8575889: Numata O (1996) Multifunctional proteins in Tetrahymena: 14-nm filament protein/citrate synthase and translation elongation factor-1 alpha. International review of cytology 164( ):1-35
  8. Ref:9019273: Kurasawa Y, Watanabe Y, Numata O (1996) Characterization of F-actin bundling activity of Tetrahymena elongation factor 1 alpha investigated with rabbit skeletal muscle actin. Zoological science 13(3):371-5

Sequences 

>TTHERM_00516370(coding)
ATGAAGACTCTCTAAATTGAGAAGATAAGAGAACTCATGATGAACCCTAACCAAATCAGA
AATATGTCTGTCATAGCCCACGTTGATCATGGTAAGACTACTTTAACTGATTCCTTATTA
GCTAGAGCTGGTATCATATCTGAAAACAACGCTGGTAAAGCATGTTTGATGGATACTGAC
CCTAAGGAGTAAGAAATGGGCATCACCATTAAGTCTACTGGAGTTTCCTTATACTATCAA
AATACTGTGACCAAGTAGGAGAGTATCATTAATTTGATTGATTCTCCTGGTCATATTGAC
TTTTCTGGTGAAGTCACTGCTGCTTTAAGAGTTACTGATGGAGCTCTTGTAGTAGTGGAT
GCTGTTGAAGGTGTTGCTGTTCAGACAGAAACAGTTCTAAGGCAGGCTTGCCAAGAGCGA
ATACGACCCGTTCTTGTAATTAATAAGCTAGACAGGCTTTTTAGTGAACTTAAGGATGAT
TATGAAAATATTTATCAAAGACTTGTTAAGATTATAGCAAAAGTTAATTCCATCTTAGAG
ATGCATGAAAACGATTCTATCAGAGGTTACACTTTAGATCCTTCACTAGGTAACGTTGCC
TTCTCTTCTGGTAAGTAGTGTTGGGGATTCACCTTAAAAACTTTTGCAAGAATTTACAGC
CAAAAATTCTCAACCAAGGAGGAAACCTTAATGGCTAAGTTATGGGGAGATAACTACTTT
AACTCTCAAACCAAATCATTCACCTCAGAAATAACCAAAATTAATAACTAAAACAAGAAA
GCTTTGCGCTCTTTCATTGAATTCGTTTTAGTTCCTTTAGATAAGTACTACTCTGCTTCT
TCAAGCGCAGATGTAGAAGTTCTATCTAAGATGGTTGAAAAGCTCAACCTCTCTACTATT
TTAACTACAGCTGAATTAGAAAGACTCAAACAAGTTGATGTTCAAGAGAGAATCAAAAGA
ACTATGAGAGCTTGGTTACCTTTAGCAGATGCTATACTTGAAATGGTCTAAGATCACCTT
CCTTCGCCTAAAGAAGCTATGAAGTATCGTAGTTTGTATCTCTACGAAGGGCCTGCAGAT
GATGAGGCTTGCACAGCCATGAGAGAATGTAATTCTGAGGGACCTCTTATGCTTTATGTT
TCAAAAATGGTCCCAACTGCAGATCTCAGCAGATTTTATGCTTTCGGTAGAGTATTCAGT
GGTACAATTTCTCAAGGAATGAAAGTTAGAGTTCAAGGCCCTGATTACAAGCCAGGAAGT
AAGGAAGGTCTCTTTATCAAAACTATCTAGAGAACCTTTTTGATGATGGGTAAATAACAC
GAACCTATCGAATCAGTACCAGCTGGAGGTACTGTCCTCATTTTAGGTGTTGATAATGCA
CTTACTAAGACAGGCACTCTTACAACTTCTGAAACAGCACATAATATCAGAAACATGAAA
TATACGATTTCACCTATATTGAGAGTTGCTGTTAATACTCCCAACTAGCAAGATCTTCCA
CGTCTTCTTGAAGGTCTTAAGATGCTTCAAAAGTATGACCCTCTTGTTTAAGTAGAAGTT
GATGAAAATACAGGTTCTTATGTTGTTGCTGGTGGTGGAGAGCTACACGTCCAAATTTGT
CTAGAAAAGCTCAATGATTTCACCCACAATTCTATCAATATCGTCGCTTCTCAGCCCACT
GTATCGTATAGAGAAACCATAGGTGATAAGAGTTCTTAAATGTGCCTTGCTAAGACTGCA
AATAAGTTGAATCGTTTATATGGTACTTGCGAACCTCTAGATGAAGAATTAGGATCAGCT
ATTGTAAGCAACAAAATAAATATACAGGAAATCAATAGTTAAGAAACAATCAACAGTTTG
GTGAATGATTACTCATGGGAAAGAGAAGATGCAAAGCGTATATGGTGCTTCGGTCCTCTA
GAAAAGGAATCAACTAATTGCATCGTAAACCAAACAGTTGGTATATAAGGTATGCCTGCC
ATTCAGCCTTCAATCATAACAGCTTTCGAATGGTGTACAAAGGAAGGTCTTTTATGTGAT
GAACCCCTAAGAAATATTCGTTTTAACATTATGGATGCAGTAATACATGTAGATCCAGCT
CACCATCGTAGCAATTAAATAACACCAGCTGCTAGAAGATTATTTAAGGCTTGCCAATAT
GTGAGTGAACCTAAAATTCTGGAGCCATTTTACTTATGCGACATTAGAATTCCAGACGAA
AGCAAAGGCCCTATATATGCAGTCTTAAACAAGAGAAGAGGTATAGTTGTTGGAGAAGAA
TATGAAGATACACTCTCTGTGATATAAGCCCACATCCCTGTATCTGAAAGCTTTGGACTA
GACTAAGCCCTGAAGTCAGCCACTCAAGGTAAGGCTATACCTGCTCTCTCATTCAGTCAC
TGGCAAGTAGTTTAAGGCAATCCACTTGACCCAGAATCAAAATCAGGTAAGATCGTCAAT
GAAATAAGAATTAGAAAAGGTTTGAATGCTAAAATACCAGAACTCAACAACTATCTTGAT
AAACTTTGA


>TTHERM_00516370(gene)
ATGAAGACTCTCTAAATTGAGAAGATAAGAGAACTCATGATGAACCCTAACCAAATCAGA
AATATGTCTGTCATAGCCCACGTTGATCATGGTAAGACTACTTTAACTGATTCCTTATTA
GCTAGAGCTGGTATCATATCTGAAAACAACGCTGGTAAAGCATGTTTGATGGATACTGAC
CCTAAGGAGTAAGAAATGGGCATCACCATTAAGTCTACTGGAGTTTCCTTATACTATCAA
AATACTGTGACCAAGTAGGAGAGTATCATTAATTTGATTGATTCTCCTGGTCATATTGAC
TTTTCTGGTGAAGTCACTGCTGCTTTAAGAGTTACTGATGGAGCTCTTGTAGTAGTGGAT
GCTGTTGAAGGTGTTGCTGTTCAGACAGAAACAGTTCTAAGGCAGGCTTGCCAAGAGCGA
ATACGACCCGTTCTTGTAATTAATAAGCTAGACAGGCTTTTTAGTGAACTTAAGGATGAT
TATGAAAATATTTATCAAAGACTTGTTAAGATTATAGCAAAAGTTAATTCCATCTTAGAG
ATGCATGAAAACGATTCTATCAGAGGTTACACTTTAGATCCTTCACTAGGTAACGTTGCC
TTCTCTTCTGGTAAGTAGTGTTGGGGATTCACCTTAAAAACTTTTGCAAGAATTTACAGC
CAAAAATTCTCAACCAAGGAGGAAACCTTAATGGCTAAGTTATGGGGAGATAACTACTTT
AACTCTCAAACCAAATCATTCACCTCAGAAATAACCAAAATTAATAACTAAAACAAGAAA
GCTTTGCGCTCTTTCATTGAATTCGTTTTAGTTCCTTTAGATAAGTACTACTCTGCTTCT
TCAAGCGCAGATGTAGAAGTTCTATCTAAGATGGTTGAAAAGCTCAACCTCTCTACTATT
TTAACTACAGCTGAATTAGAAAGACTCAAACAAGTTGATGTTCAAGAGAGAATCAAAAGA
ACTATGAGAGCTTGGTTACCTTTAGCAGATGCTATACTTGAAATGGTCTAAGATCACCTT
CCTTCGCCTAAAGAAGCTATGAAGTATCGTAGTTTGTATCTCTACGAAGGGCCTGCAGAT
GATGAGGCTTGCACAGCCATGAGAGAATGTAATTCTGAGGGACCTCTTATGCTTTATGTT
TCAAAAATGGTCCCAACTGCAGATCTCAGCAGATTTTATGCTTTCGGTAGAGTATTCAGT
GGTACAATTTCTCAAGGAATGAAAGTTAGAGTTCAAGGCCCTGATTACAAGCCAGGAAGT
AAGGAAGGTCTCTTTATCAAAACTATCTAGAGAACCTTTTTGATGATGGGTAAATAACAC
GAACCTATCGAATCAGTACCAGCTGGAGGTACTGTCCTCATTTTAGGTGTTGATAATGCA
CTTACTAAGACAGGCACTCTTACAACTTCTGAAACAGCACATAATATCAGAAACATGAAA
TATACGATTTCACCTATATTGAGAGTTGCTGTTAATACTCCCAACTAGCAAGATCTTCCA
CGTCTTCTTGAAGGTCTTAAGATGCTTCAAAAGTATGACCCTCTTGTTTAAGTAGAAGTT
GATGAAAATACAGGTTCTTATGTTGTTGCTGGTGGTGGAGAGCTACACGTCCAAATTTGT
CTAGAAAAGCTCAATGATTTCACCCACAATTCTATCAATATCGTCGCTTCTCAGCCCACT
GTATCGTATAGAGAAACCATAGGTGATAAGAGTTCTTAAATGTGCCTTGCTAAGACTGCA
AATAAGTTGAATCGTTTATATGGTACTTGCGAACCTCTAGATGAAGAATTAGGATCAGCT
ATTGTAAGCAACAAAATAAATATACAGGAAATCAATAGTTAAGAAACAATCAACAGTTTG
GTGAATGATTACTCATGGGAAAGAGAAGATGCAAAGCGTATATGGTGCTTCGGTCCTCTA
GAAAAGGAATCAACTAATTGCATCGTAAACCAAACAGTTGGTATATAAGGTATGCCTGCC
ATTCAGCCTTCAATCATAACAGCTTTCGAATGGTGTACAAAGGAAGGTCTTTTATGTGAT
GAACCCCTAAGAAATATTCGTTTTAACATTATGGATGCAGTAATACATGTAGATCCAGCT
CACCATCGTAGCAATTAAATAACACCAGCTGCTAGAAGATTATTTAAGGCTTGCCAATAT
GTGAGTGAACCTAAAATTCTGGAGCCATTTTACTTATGCGACATTAGAATTCCAGACGAA
AGCAAAGGCCCTATATATGCAGTCTTAAACAAGAGAAGAGGTATAGTTGTTGGAGAAGAA
TATGAAGATACACTCTCTGTGATATAAGCCCACATCCCTGTATCTGAAAGCTTTGGACTA
GACTAAGCCCTGAAGTCAGCCACTCAAGGTAAGGCTATACCTGCTCTCTCATTCAGTCAC
TGGCAAGTAGTTTAAGGCAATCCACTTGACCCAGAATCAAAATCAGGTAAGATCGTCAAT
GAAATAAGAATTAGAAAAGGTTTGAATGCTAAAATACCAGAACTCAACAACTATCTTGAT
AAACTTTGA


>TTHERM_00516370(protein)
MKTLQIEKIRELMMNPNQIRNMSVIAHVDHGKTTLTDSLLARAGIISENNAGKACLMDTD
PKEQEMGITIKSTGVSLYYQNTVTKQESIINLIDSPGHIDFSGEVTAALRVTDGALVVVD
AVEGVAVQTETVLRQACQERIRPVLVINKLDRLFSELKDDYENIYQRLVKIIAKVNSILE
MHENDSIRGYTLDPSLGNVAFSSGKQCWGFTLKTFARIYSQKFSTKEETLMAKLWGDNYF
NSQTKSFTSEITKINNQNKKALRSFIEFVLVPLDKYYSASSSADVEVLSKMVEKLNLSTI
LTTAELERLKQVDVQERIKRTMRAWLPLADAILEMVQDHLPSPKEAMKYRSLYLYEGPAD
DEACTAMRECNSEGPLMLYVSKMVPTADLSRFYAFGRVFSGTISQGMKVRVQGPDYKPGS
KEGLFIKTIQRTFLMMGKQHEPIESVPAGGTVLILGVDNALTKTGTLTTSETAHNIRNMK
YTISPILRVAVNTPNQQDLPRLLEGLKMLQKYDPLVQVEVDENTGSYVVAGGGELHVQIC
LEKLNDFTHNSINIVASQPTVSYRETIGDKSSQMCLAKTANKLNRLYGTCEPLDEELGSA
IVSNKINIQEINSQETINSLVNDYSWEREDAKRIWCFGPLEKESTNCIVNQTVGIQGMPA
IQPSIITAFEWCTKEGLLCDEPLRNIRFNIMDAVIHVDPAHHRSNQITPAARRLFKACQY
VSEPKILEPFYLCDIRIPDESKGPIYAVLNKRRGIVVGEEYEDTLSVIQAHIPVSESFGL
DQALKSATQGKAIPALSFSHWQVVQGNPLDPESKSGKIVNEIRIRKGLNAKIPELNNYLD
KL