Identifiers and Description

Gene Model Identifier

TTHERM_00526730

Standard Name

TAP1 (Tetrahymena Amino acid Permease )

Aliases

PreTt06411 | 66.m00210 | 3722.m00068

Description

TAP1 transmembrane amino acid transporter protein; Amino acid permease 1; similar to proton driven amino-acid pumps of the UNC-47/VGAT family

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• membrane (IEA) | GO:0016020

Molecular Function

• amino acid transmembrane transporter activity (ISS) | GO:0015171
• amino acid-polyamine transporter activity (IEA) | GO:0005279

Biological Process

• amino acid transport (IEA) | GO:0006865
• vesicle organization (IEP) | GO:0016050

Domains

• ( PF00001 ) 7 transmembrane receptor (rhodopsin family)
• ( PF00950 ) ABC 3 transport family
• ( PF01148 ) phosphatidate cytidylyltransferase
• ( PF01490 ) Transmembrane amino acid transporter protein
• ( PF03845 ) Spore germination protein
• ( PF07672 ) Mycoplasma MFS transporter
• ( PF07695 ) 7TM diverse intracellular signalling
• ( TIGR02614 ) cell division protein FtsW

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_13414.1	9.997093137033517e-262
	Description: transmembrane amino acid transporter (552 aa)
Oxytricha	Contig4642.0.g78	3.998693556225637e-29
	Description: Transmembrane amino acid transporter protein
SGD	YNL101W	7.996210139153865e-29
	Description: AVT4 Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
WormBase	WBGene00012804	3.9989916100764785e-24
	Description: status:Confirmed UniProt:O45936 protein_id:CAA16336.2
DictyBase	DDB_G0293074	0.0007999190683310628
	Description: DDB_G0293074 on chromosome: 6 position 2437739 to 2439363

General Information

No Data fetched for General Information

Associated Literature

1. Ref:12456006: Haddad A, Bowman GR, Turkewitz AP (2002) New class of cargo protein in Tetrahymena thermophila dense core secretory granules. Eukaryotic cell 1(4):583-93
2. Ref:17821280: Harrison JA, Fowler EH (1945) AN ANTIGEN-ANTIBODY REACTION WITH TETRAHYMENA WHICH RESULTS IN DYSTOMY. Science (New York, N.Y.) 102(2638):65-6

Sequences

>TTHERM_00526730(coding)
ATGAAGTCCAATAAAAAGTAGTAGAAAAGATAATAAGAAAGGCATGACGACCCAGATTTA
GAGCCCTTGAACAAAAAAAACGATGAATAAGTTATAGAAACTGATGAGGGCGTAATTAAG
AATCGCAGTTCATAAAAAGAAGAAAAAAAGAGCTACTAATCAAATTAGAGTGATGGAAGT
AGAATATAAAAAAGATAATCTCAAGATCAAGAAAATTGGAGTGATGATTCAGCAGAAGAA
GCTAATTAAATTGATGACTTGAAACATGAAGAAAAGGCTGATGTTTGGAATGCAACTATA
AATATGGTTAAGGGATTTGTTGGAATCGGTATTTTAGCACTACCTTCAGGTTTTGCTAAG
AGTGGTTGGTTGGGAGGATTAATAATTTTTTTGCTTTGCGCTGGAATGGTTCTTTATTTA
AGTTTATAGATGATGGATGCAGCAAACAAAAGAAAATCTTAAGCTAGAGGTGTTACCTAA
TTCAGTGTTGAAGTTTTGGGATAAGAAAAAGAATTATTAGTTAATATATTTTTATTTGGA
ATCTAAATTGGAATTTGTGTTGCCTATGTTATTTTCTTCACTACTTATTTTTAAGAGAGT
CTTTGTTTCTTTGTAGATTATGATCGTACAACTAATGTATGTGGTTCAAGAGTTCCTTCG
TTACTCATTTCACTTATAATCGTTACTCCTACAATATTTATCAGACACATGAGTAAACTT
AAAACTTGGAGCATGTTTTCAAATAGTTTAATTCTTATTAGTATGCTTGTAGTATTTATT
TCTTGCTTTTTTAAAATGGACACTTCTTACATTACTAGTGACAAAATTTCAGCTATCAGA
TGGGGAGAAATGGGTAGTGCAATAGGTTTATTTGTGTTTGCATTTGAAGGAACCACTCTT
TATTTTGAAATTAGGAGTTCTATGCAAGAACCAACTGAGTTCAAAAAGGTTCTTAATTAT
TCTCTTTATATTGGTATTGCTCTTTATGGGTGCATTGGTTTGAGTGGATATTTAGCTTTT
GGATCAGGTGTTAGAGACATCATACTTTTTAATTTCCCTATGACTAATCCCTTGTATGTT
TTTATTTAAATCTTTTACTGTATAGCAATATTGTTATCCTATCCTCTTCAGATGTTCCCT
TTAGTCAATATCTTAGAATAAAAATTATTAGAAAGGATAGTCAATGAAAAGAATAAATAA
AAAACAAATAGCTAGCCCTAAAAAAAGTCATAGCAAGGTGTAGATTAAAGCCAACATCAT
AATTAAGGTAATCAGCAAGCAGACGATAGATAAGATAACTAGGAATCTGATGCATCAGAA
GGAAATGCATTGAACTTATTAACATAATATGATGATGAAATAAAAAATTCATTTTACTAA
TAAAGCATGATATTAAGAGTAGCTTCTCTTTTATTCATATTCTTTTTTGCAATCGTCTTT
AAAAGACTAACTGTCTTTTTAAATTTAATTGGTTCTATTGGTGGTTGCTTTTTTGCATTT
ATTTTACCAGTCATTGTCTATGAGTATTCTATGCCAGAAGCTTCACAAAAAAAAATATAC
TTTCACAGAGGCTTACTTGTACTAGGTGTTATTTTTTCCTTCTTTGGTACTCTTTCTAGT
TTAAGAGATATCTATAGATCGTTATGA

>TTHERM_00526730(gene)
ATGAAGTCCAATAAAAAGTAGTAGAAAAGATAATAAGAAAGGCATGACGACCCAGATTTA
GAGCCCTTGAACAAAAAAAACGATGAATAAGTTATAGAAACTGATGAGGGCGTAATTAAG
AATCGCAGTTCATAAAGTAAGGAGAAGATCTTTAAATATTTTAAAGAATTGTTAATAATC
ATTTTATTTGATTATTTGGAATTTATTTTTTTTATATAATTTCAAAGAAGAAGAAAAAAA
GAGCTACTAATCAAATTAGAGTGATGGAAGTAGAATATAAAAAAGATAATCTCAAGATCA
AGAAAATTGGAGTGATGATTCAGCAGAAGAAGCTAATTAAATTGATGACTTGAAACATGA
AGAAAAGGCTGATGTTTGGAATGCAACTATAAATATGGTTAAGGGATTTGTTGGAATCGG
TATTTTAGCACTACCTTCAGGTTTTGCTAAGAGTGGTTGGTTGGGAGGATTAATAATTTT
TTTGCTTTGCGCTGGAATGGTTCTTTATTTAAGTTTATAGATGATGGATGCAGCAAACAA
AAGAAAATCTTAAGCTAGAGGTGTTACCTAATTCAGTGTTGAAGTTTTGGGATAAGAAAA
AGAATTATTAGTTAATATATTTTTATTTGGAATCTAAATTGGAATTTGTGTTGCCTATGT
TATTTTCTTCACTACTTATTTTTAAGAGAGTCTTTGTTTCTTTGTAGATTATGATCGTAC
AACTAATGTATGTGGTTCAAGAGTTCCTTCGTTACTCATTTCACTTATAATCGTTACTCC
TACAATATTTATCAGACACATGAGTAAACTTAAAACTTGGAGCATGTTTTCAAATAGTTT
AATTCTTATTAGTATGCTTGTAGTATTTATTTCTTGCTTTTTTAAAATGGACACTTCTTA
CATTACTAGTGACAAAATTTCAGCTATCAGATGGGGAGAAATGGGTAGTGCAATAGGTTT
ATTTGTGTTTGCATTTGAAGGAACCACTCTTTATTTTGAAATTAGGTAAATTTATTTCAC
AAAAATTTTTTTAAATAATTTTTTAAAATAACAATTTTTTTCAAATTAATAGGAGTTCTA
TGCAAGAACCAACTGAGTTCAAAAAGGTTCTTAATTATTCTCTTTATATTGGTATTGCTC
TTTATGGGTGCATTGGTTTGAGTGGATATTTAGCTTTTGGATCAGGTGTTAGAGACATCA
TACTTTTTAATTTCCCTATGACTAATCCCTTGTATGTTTTTATTTAAATCTTTTACTGTA
TAGCAATATTGTTATCCTATCCTCTTCAGATGTTCCCTTTAGTCAATATCTTAGAATAAA
AATTATTAGAAAGGATAGTCAATGAAAAGAATAAATAAAAAACAAATAGCTAGCCCTAAA
AAAAGTCATAGCAAGGTGTAGATTAAAGCCAACATCATAATTAAGGTAATCAGCAAGCAG
ACGATAGATAAGATAACTAGGAATCTGATGCATCAGAAGGAAATGCATTGAACTTATTAA
CATAATATGATGATGAAATAAAAAATTCATTTTACTAATAAAGCATGATATTAAGAGTAG
CTTCTCTTTTATTCATATTCTTTTTTGCAATCGTCTTTAAAAGACTAACTGTCTTTTTAA
ATTTAATTGGTTCTATTGGTGGTTGCTTTTTTGCATTTATTTTACCAGTCATTGTCTATG
AGTATTCTATGCCAGAAGCTTCACAAAAAAAAATATACTTTCACAGAGGCTTACTTGTAC
TAGGTGTTATTTTTTCCTTCTTTGGTACTCTTTCTAGTTTAAGAGATATCTATAGATCGT
TATGA

>TTHERM_00526730(protein)
MKSNKKQQKRQQERHDDPDLEPLNKKNDEQVIETDEGVIKNRSSQKEEKKSYQSNQSDGS
RIQKRQSQDQENWSDDSAEEANQIDDLKHEEKADVWNATINMVKGFVGIGILALPSGFAK
SGWLGGLIIFLLCAGMVLYLSLQMMDAANKRKSQARGVTQFSVEVLGQEKELLVNIFLFG
IQIGICVAYVIFFTTYFQESLCFFVDYDRTTNVCGSRVPSLLISLIIVTPTIFIRHMSKL
KTWSMFSNSLILISMLVVFISCFFKMDTSYITSDKISAIRWGEMGSAIGLFVFAFEGTTL
YFEIRSSMQEPTEFKKVLNYSLYIGIALYGCIGLSGYLAFGSGVRDIILFNFPMTNPLYV
FIQIFYCIAILLSYPLQMFPLVNILEQKLLERIVNEKNKQKTNSQPQKKSQQGVDQSQHH
NQGNQQADDRQDNQESDASEGNALNLLTQYDDEIKNSFYQQSMILRVASLLFIFFFAIVF
KRLTVFLNLIGSIGGCFFAFILPVIVYEYSMPEASQKKIYFHRGLLVLGVIFSFFGTLSS
LRDIYRSL