Identifiers and Description

Gene Model Identifier

TTHERM_00569290

Standard Name

LIA2 (localized in macronuclear anlagen 2)

Aliases

PreTt10459 | 76.m00161 | 3810.m02020 | DRH3

Description

LIA2 DEAD/DEAH-box helicase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• ATP-dependent helicase activity (IEA) | GO:0008026
• helicase activity (IEA) | GO:0004386
• nucleic acid binding (IEA) | GO:0003676

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_03481.1	9.997093137033517e-262
	Description: DEAD/DEAH box helicase (588 aa)
DictyBase	DDB_G0293168	9.997105718980434e-168
	Description: ddx17 on chromosome: 6 position 2360817 to 2364250
SGD	YNL112W	6.998455025673696e-155
	Description: DBP2 Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing
Oxytricha	Contig21312.0.g80	3.9992399120784785e-154
	Description: DEAD/DEAH box helicase
WormBase	WBGene00010260	5.997411300273806e-139
	Description: locus:ddx-17 status:Confirmed UniProt:Q9XUW5 protein_id:CAB04518.1
Stentor Coeruleus	SteCoe_12603	1.7785284761271306e-68
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:27892853: Hamilton EP, Kapusta A, Huvos PE, Bidwell SL, Zafar N, Tang H, Hadjithomas M, Krishnakumar V, Badger JH, Caler EV, Russ C, Zeng Q, Fan L, Levin JZ, Shea T, Young SK, Hegarty R, Daza R, Gujja S, Wortman JR, Birren BW, Nusbaum C, Thomas J, Carey CM, Pritham EJ, Feschotte C, Noto T, Mochizuki K, Papazyan R, Taverna SD, Dear PH, Cassidy-Hanley DM, Xiong J, Miao W, Orias E, Coyne RS (2016) Structure of the germline genome of Tetrahymena thermophila and relationship to the massivel
2. Ref:27793833: McDaniel SL, Zweifel E, Harris PK, Yao MC, Cole ES, Chalker DL (2016) DRH1, a p68-related RNA helicase gene, is required for chromosome breakage in Tetrahymena. Biology open 5(12):1790-1798
3. Ref:17519286: Yao MC, Yao CH, Halasz LM, Fuller P, Rexer CH, Wang SH, Jain R, Coyne RS, Chalker DL (2007) Identification of novel chromatin-associated proteins involved in programmed genome rearrangements in Tetrahymena. Journal of cell science 120(Pt 12):1978-89

Sequences

>TTHERM_00569290(coding)
ATGTGGGGAAATAGCTACAATAATAATAGTTCTAGTAATGGATACTCAAATAACAAAAGC
AACGGATATTCAAGCAGCAATAATAATGGAAACTCCTATGGAACCGGTGGCAAGTGGAAT
GATAACGGAGTTGGTTAAAATTTGGCTGCAATCGATTGGACAAAAGAAAATCTTACTACA
TTTTAGAAAGTTTTTTATAAGGAAAGTTAGAAAATAAGAACTGAAGAAGAAATCGAAGAA
TTTTACCGCCAGAACCACATCTCAGCCAAATCACCTCATGGAAAAGTACCTGACCCTTTT
TTAAGCTGGACAGATACTCACTTCCCTTAATATATTATGAATGAAGTTACTCACGCTAAA
TTTGAAAAACCCTCTCCTATTTAGTCTTTAGCATTCCCTGTAGTCCTTAGTGGTCACGAT
TTGATTGGTATTGCAGAAACAGGTAGTGGAAAAACTCTTTCCTTCCTTTTACCCTCAATA
GTTCATATTAATGCTCAACCAACTGTCAAAAAGGGAGATGGTCCTATCGTCCTCGTTCTT
GCTCCTACTAGAGAACTTGCTATGCAAATCGAAAGAGAGTCCGAAAGATTTGGTAAATCC
TCTAAGCTTAAATGTGCTTGTATCTATGGTGGTGCTGACAAATACTCCTAAAGAGCACTT
CTCCAATAAGGTGTAGATGTAGTTATTGCTACTCCTGGTAGACTTATTGACTTTTTAGAA
AGTGAAACTACTACTTTACGTAGAGTTACTTATCTCGTATTAGATGAAGCAGATAGAATG
TTAGATATGGGTTTTGAAATTTAAATTAGAAAAATCTTGGGTTAAATTAGACCTGATCGT
TAAACATTGATGTTTTCTGCTACCTGGCCTAAGAATGTTTAGAATCTTGCTTAAGATTAT
TGCAAGAATACTCCCGTTTATGTTCAAATCGGAAAACATGAATTAGCTATTAACGAAAGA
ATTAAATAAATTGTTTATGTTACAGATCAATCAAAGAAAATCAATCAACTTATCAAGCAA
TTAGATTGTTTGACTTAGAAAGATAAAGTATTGATTTTCGCTTAAACAAAGAAGGGATGT
GAAAGCATGAGTCGTATTTTGAATAAAGAAGGATTTAAGTGTCTTGCTATCCATGGTGAC
AAAGCCTAAAAAGACAGAGACTATGTTATGAACAAGTTCAAAAGCGGAGAATGCAGAATC
CTTATTGCTACAGACGTAGCCAGTAGAGGTTTGGATGTTAAGGATGTCTCCCACGTATTT
AATTACGATTTCCCAAAGGTTATGGAAGACTATGTCCATAGAATCGGTAGAACAGGTAGA
GCTGGAGCATATGGTTGTGCAGTATCTTTCCTTACTTTTGAAGATGATAAAAAGATATCA
AGGGAATATGTCCAAATGCTTCATGACGCTAAGTAAGAAATTCCCATTGATCTTCTTGAT
CTTGCTAATCCCAGATACAGAACTTAATATAAAACTGTTTCCTCTTCATACTATGATATT
AAGAAATTTAACAGTGCTGATACTTCAAAGCCTTCAGAAAATCAGAATGTTTCAAATACT
GCAAATAGCAGCGACAAGTACACCAGCAGTAGCAGCTACAATTAATATAAAAGCAAAAAA
GATGAAGATGACAAGAGAAGTAGAAGTAGAAGTCCATATAAATCTGAAAATAACAACAGA
TGGGATAAATATAATCGCACAAAAAGCCCAGAATACCGCAGTTCTAATGGATCTTCTCAT
TATAACAACGTTAACAAGTATTCTTCAAATTCTAATAATAATTCAAGTTCATATTCAAAG
AATTAATCCTCCACATCATCATCTTCTTCCTATGGATAGAATAATTAATCATCCAATTTA
ATGAGTAAACCATCTAGTAAATTCTCTGCTCCTACAAATGGTAGTTACACAAATGGATTT
TCTTCAGTCTAATAAAATTCTCAAGTTTAAAATCCATTTATGCCAATCAATCCTTTACCT
CAACCTTTTATGTACTAAATTCCTGGATTTAATGGTTTCCCTAATCAAGGTTTCAATAAC
TTTTACACTGGTATGGTTCCTCCTCCTCCACTCCCTACTGGTGCTCCCTCATAATAATAA
AATGGATTTGCTTAAAATACAACAACATCTTCTTGA

>TTHERM_00569290(gene)
ATGTGGGGAAATAGCTACAATAATAATAGTTCTAGTAATGGATACTCAAATAACAAAAGC
AACGGATATTCAAGCAGCAATAATAATGGAAACTCCTATGGAACCGGTGGCAAGTAATAT
TTCTATTTCACTTTTCTTAAATTTTCTTATCTCTCTTAGCTCCTTTTAGGCTAAGAGCTT
AGCAAGATATTTAAATCAAAGTCTGGGACAATGATTTGAAACATTTCTATTTAAAAATTA
GGTGGAATGATAACGGAGTTGGTTAAAATTTGGCTGCAATCGATTGGACAAAAGAAAATC
TTACTACATTTTAGAAAGTTTTTTATAAGGAAAGTTAGAAAATAAGAACTGAAGAAGAAA
TCGAAGAATTTTACCGCCAGAACCACATCTCAGCCAAATCACCTCATGGAAAAGTACCTG
ACCCTTTTTTAAGCTGGACAGATACTCACTTCCCTTAATATATTATGAATGAAGTTACTC
ACGCTAAATTTGAAAAACCCTCTCCTATTTAGTCTTTAGGTATTGTTTGATTGAATTTAA
ACCAACAAACCAACCTACGATGGAACATTTTGAAACATAAATAAATAAATAAAAACCTAC
ACACATAGTTTGTTTAAAATATATTTGCAAAAAATAAACATTTAAACAAGCCAATTTCTA
CACTTAGCATACAAAATTCAAATCACAAACGAGTGTGTGTAATTTAATTAACAATATATA
TCAATGCGGGAATCAATCAATCAATGTTAAGAAGAAGCCAAAGGTTATTCCTTAAGAATA
AGCATCGCTCAATGTTTCCAAAGAGACCAATGTATTTATTCAATATGAATCTACTTGAAT
AAAGGTGAATTTATTCTTTCTGAGGGAATTATTGATCGAAGTGCTTATCATCCTCATTCT
TAATATTGTTTGTACAGCAGATTATTATCAGGAGGAGAACGAAATGGATCCAAAAAAGAT
AATCAGAGCTGAATGTAACTGTACTGTCATTTATCTTTTTGATTCATTTCAATTCTCTTG
AAAAACTGCATTTTCCCTTCAGAATTTTGATTTTCAAATCAATCATCCATTCTATTTCAC
ATTTCCATCTTAAAAAAGAAACAATCATCCCCGTCATTTATTTATTCCTTACAGCCAACA
AATTTCATTTATAAACTTATATTTATTTTAATAATCCTTCAGTATAACCATATAATTTGG
CTTTTTTGCTAAATTTTAAACACAAATCAATCAATCAATCAAAAATAAATTTAAATAGGA
TAGACAGATGTATCAATTTGCATATATTTAAAATAAATAGCCTTTGCAAATTTTCAAATT
TGCTTTATTATATAATTAATTTGTCTAATAACTTTAATCTAATTTTTTTTTTTTTCATTA
TTGATTGATAGAGGATTGACAAACAAAATTATCTTTTTTTTAAACAAATAATGAAATTTA
CAAGAGTTTGAAAAATCAAATTCTAAAGGGAAAATTATTTTTATCGCTCAATATTGTTTC
TTTTCATTATAGATTATTTTATCAAAAGCTCTATTTATTGGAAAAATTTACTTACCAATT
TATAGCTGATTAATAATTACTACTCACAAATGATTAAATATTTATAAGTTTGATTTTCCC
TAAAATTAACTAGCATTCCCTGTAGTCCTTAGTGGTCACGATTTGATTGGTATTGCAGAA
ACAGGTAGTGGAAAAACTCTTTCCTTCCTTTTACCCTCAATAGTTCATATTAATGCTCAA
CCAACTGTCAAAAAGGGAGATGGTCCTATCGTCCTCGTTCTTGCTCCTACTAGAGAACTT
GCTATGCAAATCGAAAGAGAGTCCGAAAGATTTGGTAAATCCTCTAAGCTTAAATGTGCT
TGTATCTATGGTGGTGCTGACAAATACTCCTAAAGAGCACTTCTCCAATAAGGTGTAGAT
GTAGTTATTGCTACTCCTGGTAAATATATATCAACATTTGAACACTTTTAACCAACTTTC
AAATAAATTTCTTAAATTAAACTTTTTTTTAATTTAAATTACAGGTAGACTTATTGACTT
TTTAGAAAGTGAAACTACTACTTTACGTAGAGTTACTTATCTCGTATTAGATGAAGCAGA
TAGAATGTTAGATATGGGTTTTGAAATTTAAATTAGAAAAATCTTGGGTTAAATTAGACC
TGATCGTTAAACATTGATGTTTTCTGCTACCTGGCCTAAGAATGTTTAGAATCTTGCTTA
AGATTATTGCAAGAATACTCCCGTTTATGTTCAAATCGGAAAACATGAATTAGCTATTAA
CGAAAGAATTAAATAAATTGTTTATGTTACAGATCAATCAAAGAAAATCAATCAGTATTT
AAATATTTTAACAATTATTTTTTCAATTATCTAAATATTCTTTTTTAATTAATAGACTTA
TCAAGCAATTAGATTGTTTGACTTAGAAAGATAAAGTATTGATTTTCGCTTAAACAAAGA
AGGGATGTGAAAGCATGAGTCGTATTTTGAATAAAGAAGGATTTAAGTGTCTTGCTATCC
ATGGTGACAAAGCCTAAAAAGACAGAGACTATGTTATGAACAAGTTCAAAAGCGGAGAAT
GCAGAATCCTTATTGCTACAGACGTAGCCAGTAGAGGTTTGGATGTTAAGGATGTCTCCC
ACGTATTTAATTACGATTTCCCAAAGGTTATGGAAGACTATGTCCATAGAATCGGTAGAA
CAGGTAGAGCTGGAGCATATGGTTGTGCAGTATCTTTCCTTACTTTTGAAGATGATAAAA
AGATATCAAGGGAATATGTCCAAATGCTTCATGACGCTAAGTAAGAAATTCCCATTGATC
TTCTTGATCTTGCTAGTATTAGTAATTATTTATTAATATGAATTCAATTCTAAATTTTTT
ACTTAAATAAAATAGATCCCAGATACAGAACTTAATATAAAACTGTTTCCTCTTCATACT
ATGATATTAAGAAATTTAACAGTGCTGATACTTCAAAGCCTTCAGAAAATCAGAATGTTT
CAAATACTGCAAATAGCAGCGACAAGTACACCAGCAGTAGCAGCTACAATTAATATAAAA
GCAAAAAAGATGAAGATGACAAGAGAAGTAGAAGTAGAAGTCCATATAAATCTGAAAATA
ACAACAGATGGGATAAATATAATCGCACAAAAAGCCCAGAATACCGCAGTTCTAATGGAT
CTTCTCATTATAACAACGTTAACAAGTATTCTTCAAATTCTAATAATAATTCAAGTTCAT
ATTCAAAGAATTAATCCTCCACATCATCATCTTCTTCCTATGGATAGAATAATTAATCAT
CCAATTTAATGAGTAAACCATCTAGTAAATTCTCTGCTCCTACAAATGGTAGTTACACAA
ATGGATTTTCTTCAGTCTAATAAAATTCTCAAGTTTAAAATCCATTTATGCCAATCAATC
CTTTACCTCAACCTTTTATGTACTAAATTCCTGGATTTAATGGTTTCCCTAATCAAGGTT
TCAATAACTTTTACACTGGTATGGTTCCTCCTCCTCCACTCCCTACTGGTGCTCCCTCAT
AATAATAAAATGGATTTGCTTAAAATACAACAACATCTTCTTGA

>TTHERM_00569290(protein)
MWGNSYNNNSSSNGYSNNKSNGYSSSNNNGNSYGTGGKWNDNGVGQNLAAIDWTKENLTT
FQKVFYKESQKIRTEEEIEEFYRQNHISAKSPHGKVPDPFLSWTDTHFPQYIMNEVTHAK
FEKPSPIQSLAFPVVLSGHDLIGIAETGSGKTLSFLLPSIVHINAQPTVKKGDGPIVLVL
APTRELAMQIERESERFGKSSKLKCACIYGGADKYSQRALLQQGVDVVIATPGRLIDFLE
SETTTLRRVTYLVLDEADRMLDMGFEIQIRKILGQIRPDRQTLMFSATWPKNVQNLAQDY
CKNTPVYVQIGKHELAINERIKQIVYVTDQSKKINQLIKQLDCLTQKDKVLIFAQTKKGC
ESMSRILNKEGFKCLAIHGDKAQKDRDYVMNKFKSGECRILIATDVASRGLDVKDVSHVF
NYDFPKVMEDYVHRIGRTGRAGAYGCAVSFLTFEDDKKISREYVQMLHDAKQEIPIDLLD
LANPRYRTQYKTVSSSYYDIKKFNSADTSKPSENQNVSNTANSSDKYTSSSSYNQYKSKK
DEDDKRSRSRSPYKSENNNRWDKYNRTKSPEYRSSNGSSHYNNVNKYSSNSNNNSSSYSK
NQSSTSSSSSYGQNNQSSNLMSKPSSKFSAPTNGSYTNGFSSVQQNSQVQNPFMPINPLP
QPFMYQIPGFNGFPNQGFNNFYTGMVPPPPLPTGAPSQQQNGFAQNTTTSS