Identifiers and Description

Gene Model Identifier

TTHERM_00577030

Standard Name

APM1 (Adaptor Protein complex Medium subunit 1 )

Aliases

PreTt28990 | 77.m00202 | 3812.m02678

Description

APM2 clathrin adapter protein AP-1 mu subunit; Homolog of adaptor protein complex (AP-2) medium (mu) subunit; localized near coated pits and contractile vacuole pores

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Molecular Function

• basic amino acid transmembrane transporter activity (IEA) | GO:0015174
• hormone binding (ISS) | GO:0042562 | Ref:16276403
• hormone binding (IEA) | GO:0042562
• quinoprotein glucose dehydrogenase activity (IEA) | GO:0008876

Biological Process

• negative regulation of mesodermal cell fate determination (IEA) | GO:0048335
• positive regulation of axial mesodermal cell fate determination (ISS) | GO:0048326 | Ref:16276403
• regulation of slow-twitch skeletal muscle fiber contraction (IDA) | GO:0031449 | Ref:16276403
• ribonucleotide catabolic process (IDA) | GO:0009261 | Ref:16276403

Domains

No Data fetched for Domains

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_9626	0
	Description: None
Tetrahymena borealis	EI9_04058.1	9.997093137033517e-262
	Description: adaptor complexes medium subunit protein (433 aa)
Oxytricha	Contig21325.0.g90	9.997316819378982e-180
	Description: Adaptor complexes medium subunit family
DictyBase	DDB_G0277139	8.001983224960958e-155
	Description: apm2 on chromosome: 2 position 7788092 to 7789756
WormBase	WBGene00001082	8.00283818813536e-121
	Description: locus:dpy-23 AP-2 complex subunit mu status:Confirmed UniProt:P35603 protein_id:CCD68419.1
SGD	YPL259C	8.002331242114626e-85
	Description: APM1 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1); binds clathrin; involved in clathrin-dependent Golgi protein sorting

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16276403: Elde NC, Morgan G, Winey M, Sperling L, Turkewitz AP (2005) Elucidation of clathrin-mediated endocytosis in tetrahymena reveals an evolutionarily convergent recruitment of dynamin. PLoS genetics 1(5):e52

Sequences

>TTHERM_00577030(coding)
ATGATTAGCTCTATTGTTTTTATTAACTCTAAAGGTGAAATCTTAATTTATAGAATTTAT
AAGGATGATATTAGCAGAGCAGAGACTATGTAATTCTGCACAAATGTAGTAGCTCGTAAG
GAAAGCAAAGAATCCCCTATTGTAAACATAGATGGTACTTCATTTATCCACGTCAGCTAC
AAAGATATAATATTATTAGCCACAACTAAATGTAATATAAATGCTGCTATGACAATTTAG
TTTCTTTATTAGTTGATAAATGTTTGCAAGTCCTATTTTGGTGATTTCGATGAAAACAAT
ATTCGTAAATAGTTTGTTCTCATCTATGAATTGCTCGATGAAATTATGGATTATGGTCTT
CCTTAAATTCTAGACCCCGATCTTTTAAAGTAATCAATTCAAGAAGGAGGCAAGCAAGAT
GGCATGACTGATATAGAAAAATTAAAATAATTTACTTAATAAGCTACTAATGCTTAATCG
TGGAGAGCACCAAACATTTTCTACAAAAAGAATGAAGTCTACATTGATATTATAGAAAGC
GTAAATGTAAGTATGTCAGTTAAGGGATCTATCCTTAAAGCTGATGTCTCAGGAAAAGTT
ATGGTAAAAGCTCTACTCAGTGGTGTCCCTGATTGTAAATTTGGTATGAATGACAAGGTC
TTAATGGAAAAAGAACCTCCTAAACCAGGTTCAAATCCTTAATAAGGTGGCTAAAACAAT
AAGGGTATTACAATCGATGACTTAAAGTTCCATCCTTGTGTAGTCCTTCCCAAGTTTGAC
AAAGAAAGAGCTATCACATTCACTCCTCCTGATGGTGAGTTCTAGCTAATGAGCTACAGA
ATTACTGAGAATGTCAATTTACCTTTCAAAATAATGCCCGTAATTAACGAAGATGGAAAT
AATATTGAAGTAAGAGTAAAGCTAAAATCTATTTTTGATAAAACTCAATATGCAACTAAT
GTTGCTTTAAAGGTTCCTTGCCCTAAAAATACTGCAAACACATCAAACACTGCTAGTATA
GGAAGAGCTAAATATGAACCAGAATAAGGAGGTATCGTTTGGAGAATAAAGAAGTTCTAG
GGAGAAACTGAAGCTCTTCTTAGATGTGAAATCGTGTTGAGTAATACTGCTCTTGATAAA
AATTGGGTAAAACCTCCTATATCTCTTGAATTCTAAGTTCCATCATTTACAGCAAGTGGC
TTGAGAGTAAGATTCTTGCGTATTCATGAAAAAAGTGGTTATCACCCTACAAAATGGATT
CGTTATATAACTAAGGGTGGTGAATATCTTCATCGTATATGA

>TTHERM_00577030(gene)
ATGATTAGCTCTATTGTTTTTATTAACTCTAAAGGTGAAATCTTAATTTATAGAATTTAT
AAGGATGATATTAGCAGAGCAGAGACTATGTAATTCTGCACAAATGTAGTAGCTCGTAAG
GAAAGCAAAGAATCCCCTATTGTAAACATAGATGGTACTTCATTTATCCACGTCAGCTAC
AAAGATATAATATTATTAGCCACAACTAAATGTAATATAAATGCTGCTATGACAATTTAG
TTTCTTTATTAGTTGATAAATGTTTGCAAGTCCTATTTTGGTGATTTCGATGAAAACAAT
ATTCGTAAATAGTTTGTTCTCATCTATGAATTGCTCGATGAAGTAAATATTTAAAATTTA
ACATTTAGAAATAGATTAATATGATAAACCAATCTTTATTAGTTCCCAAAAATCTAAAAA
AAAACGAAAAATAAAGTTAGTTATGTTATTTAAATAACATTTATAATCAAAGTGTAATTG
ACTATTGAAAAGGTTAATAAAATATCCTTTTAATACAATCGAATAATGGATTTATGAAGA
TATTTCTTTCTAAATAAAAATGAAATATTTGAAATCTTTAATTTATCAAAAAAAAAAATT
TTTTTTTCTTTCTATAAAAAAAGATTATGGATTATGGTCTTCCTTAAATTCTAGACCCCG
ATCTTTTAAAGTAATCAATTCAAGAAGGAGGCAAGCAAGATGGCATGACTGATATAGAAA
AATTAAAATAATTTACTTAATAAGCTACTAATGCTTAATCGTGGAGAGCACCAAACATTT
TCTACAAAAAGAATGAAGTCTACATTGATATTATAGAAAGCGTAAATGTAAGTATGTCAG
TTAAGGGATCTATCCTTAAAGCTGATGTCTCAGGAAAAGTTATGGTAAAAGCTCTACTCA
GTGGTGTCCCTGATTGTAAATTTGGTATGAATGACAAGGTCTTAATGGAAAAAGAACCTC
CTAAACCAGGTTCAAATCCTTAATAAGGTGGCTAAAACAATAAGGGTATTACAATCGATG
ACTTAAAGTTCCATCCTTGTGTAGTCCTTCCCAAGTTTGACAAAGGTAATTATTTATTTA
TTTAGTTTTTTAAATGAAAAAGGTTTGATCTCCTTTATGAAATTTCATTATTAAGTTAAA
AAAATATAGTAAAATTAAGAAATAGATAGATATGTTTGATTTCTGTCAAAAATTTGAATT
ATTTAAAAAAATAATATAAAACAGAAAGAAGGATTAAAAAAAACATAAATGTTGCAAAAT
AAAATTTCAAATAATTCAATTTTATTATAGGATTTTCACTTTAGTGCAAATTTAAATCCT
TTCAAAATAATTTTTATTTCTATTTATATATAGAAAGAGCTATCACATTCACTCCTCCTG
ATGGTGAGTTCTAGCTAATGAGCTACAGAATTACTGAGAATGTCAATTTACCTTTCAAAA
TAATGCCCGTAATTAACGAAGATGGAAATAATATTGAAGTAAGAGTAAAGCTAAAATCTA
TTTTTGATAAAACTCAATATGCAACTAATGTTGCTTTAAAGGTTCCTTGCCCTAAAAATA
CTGCAAACACATCAAACACTGCTAGTATAGGAAGAGCTAAATATGAACCAGAATAAGGAG
GTATCGTTTGGAGAATAAAGAAGTTCTAGGGAGAAACTGAAGCTCTTCTTAGATGTGAAA
TCGTGTTGAGTAATACTGCTCTTGATAAAAATTGGGTAAAACCTCCTATATCTCTTGAAT
TCTAAGTTCCATCATTTACAGCAAGTGGCTTGAGAGTAAGATTCTTGCGTATTCATGAAA
AAAGTGGTTATCACCCTACAAAATGGATTCGTTATATAACTAAGGGTGGTGAATATCTTC
ATCGTATATGA

>TTHERM_00577030(protein)
MISSIVFINSKGEILIYRIYKDDISRAETMQFCTNVVARKESKESPIVNIDGTSFIHVSY
KDIILLATTKCNINAAMTIQFLYQLINVCKSYFGDFDENNIRKQFVLIYELLDEIMDYGL
PQILDPDLLKQSIQEGGKQDGMTDIEKLKQFTQQATNAQSWRAPNIFYKKNEVYIDIIES
VNVSMSVKGSILKADVSGKVMVKALLSGVPDCKFGMNDKVLMEKEPPKPGSNPQQGGQNN
KGITIDDLKFHPCVVLPKFDKERAITFTPPDGEFQLMSYRITENVNLPFKIMPVINEDGN
NIEVRVKLKSIFDKTQYATNVALKVPCPKNTANTSNTASIGRAKYEPEQGGIVWRIKKFQ
GETEALLRCEIVLSNTALDKNWVKPPISLEFQVPSFTASGLRVRFLRIHEKSGYHPTKWI
RYITKGGEYLHRI