Identifiers and Description

Gene Model Identifier

TTHERM_00584700

Standard Name

EPK2 (EpiPlasm associated Kinase 2)

Aliases

PreTt04078 | 80.m00124 | 3675.m00022

Description

EPK2 kinase domain protein; Protein kinase domain; protein kinase family unique to Tetrahymena

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein binding (IEA) | GO:0005515
• protein kinase activity (IEA) | GO:0004672
• zinc ion binding (IEA) | GO:0008270

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00036 ) EF hand
• ( PF00069 ) protein kinase domain
• ( PF00097 ) zinc finger, C3HC4 type (RING
• ( PF00399 ) Yeast PIR protein repeat
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_15234.1	1.9994920269952867e-34
	Description: hypothetical protein (1709 aa)
Oxytricha	Contig1214.1.g96	0.0000000000000030004923591262316
	Description: Ring finger domain
WormBase	WBGene00012194	0.00000000002000577768187062
	Description: locus:toe-4 status:Partially_confirmed UniProt:Q9XUM8 protein_id:CAB04890.1
DictyBase	DDB_G0268162	0.0000008998839737394744
	Description: DDB_G0268162 on chromosome: 1 position 1580521 to 1581951
SGD	YLR247C	0.00003998524687536623
	Description: IRC20 Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00584700(coding)
ATGTTGAATCAAAATATAAACCTTGCTTAGTCCATTTCAAAGGAATAAATATCATAATAG
AATCAAGCATAAAAAAATTCTAAGATACCACTAATAATAAGAATAGCTAACAGTAGTAAT
AATTCAACTCCAGTTAAGCTAGGTTCCTTCTAGGATTTAAGTAATAATGAAGTTATTAAT
CTTTGTGAATAAGAAAATATAAAATAAGAAATCAATGATTTTAAGCCAAAAAAATAAATA
GATTGCATTGTCTTATAAAATGAATTAAATTATTTTGAAGATGAAAAAGAAGAATTTAAA
AATGACAAAAAACTACCTCAAAAACCTTAAAGAACAAGTTATATAAGCTAATAACATAAA
ACAATAGCTCAAGAATAGTATTATAATCCTATTATTCTAGCTGATAATACTAAACACAGA
GAAAGGTAGATATAAAATTAAAGAAATTAGTAAAGAAATAACTCATTAGAGAATAAATTC
ATAGAAAAATCCAATAATTAGCTAATATCAAATCGTAATCATATTAGATAGTAAAATTGT
AACAATGCTTCTTTTAATCTTATTAAAATTGACTCTTCCTAATAACTAGATATAGAAAAT
ATATAAAATTCTTCAAGTGATAGCTGTCCTGAAGTTTATTAAAAGAATAAACTAACTAAC
ATAAATTAACAATTAGATTTCAAATAAAAAAAAGATTTATTATAAATTTCAAATTTAAAT
ACTATATAAAAAGAATAATCTATAGTTTAAAGCTAGAATTTAAATAGAAATATAAAGATA
AAAAACTAGACTCCTTTACTTCCACCTATTCACCCTTAAAAATTAAAACAAGCACATTAA
TAAACTAATCATGATTTAAATAAAAATGAAATAAAAACAGATTTTATCCGTAAAAGCAGA
AGCAACTCTTTTACTGAAGAAAAAAATATTTTTAAAATGAACCTTGATAAAAGTTAAAGA
GTTTCTTCTAGTGAATTTAAGAATCTTCTTAATAATGTTAACTTTTAGTAAATACAAAAA
AATCTATCTAGAAACTAAAAATCTAAAACACAAACTAGTGAGTAAAATTATAATGTAATA
GATGATAACTCAACAAATGGAGTAATTAAAAAATATCACTAAAAACACTAAAATGATATA
AATTAATGTGCTTTTGATAGAGCTTAATACAATTAAAATATCAGATAAGAATAATAAAAT
AGTTTATTTATTTAAAGATACTAAATACCTTTAATAATTTCATAGCCTGAATTAGAATTT
ATCTAAGAAAGATCGAATAATATTAAAAATTACCCTAATCAAGTAAGATAGTAAGTTAAT
TCTCAAGAATAACCCATTAATAATGGAAACATGCAATAAAATTTAGAAAATATAAGAGAA
ATTAATGAAAGGTAAAAGTCCAAAGATGTTATAAGATTATAAAATCAAAATGTTAGAACT
TAATAACAATAACAGCAACGTAATAATAACAATAATGAATAGACATATAACGATATTATT
CAAAGAAGAAACTAAATAAATGCTTAGTAAGAAAATCTGAATGATTAATTTTAAAGTAGG
TAAAACACAATTAATTAAAATCCACCCCCAAGATTCATGATTGATAACATGTATAATTAG
TTTATAGAGTTTTAAAATCAGCTTAGATAGCATTAAGGAATTAAATCAGATAAATATGTA
AGCACAACTGTATATAAAAGTTCATAGTCTTAGAATCTTTCTTAAGATGCTAAATAGTGC
TCAATTTGTCTGTGCGAATTTGAGGATGAAGAGAAAATAAGTTTTTTGGCTTGCTTTCAT
CGTTTTCATAATGAATGCATTCACAAATGGTTTGAAACAAAATCAACTTGTCCTCTATGC
AAAAAAGATTAAAAAACATTAATAAAAGATGTTAATAAACTATTAGATGAATTTTGA

>TTHERM_00584700(gene)
ATGTTGAATCAAAATATAAACCTTGCTTAGTCCATTTCAAAGGAATAAATATCATGTAAA
TGACATTCTATTTTTGTTTTTCATAAATAACTTTTTAAAAATCTTATAAAAACTAGAATA
GAATCAAGCATAAAAAAATTCTAAGATACCACTAATAATAAGAATAGCTAACAGTAGTAA
TAATTCAACTCCAGTTAAGCTAGGTTCCTTCTAGGATTTAAGTAATAATGAAGTTATTAA
TCTTTGTGAATAAGAAAATATAAAATAAGAAATCAATGATTTTAAGCCAAAAAAATAAAT
AGATTGCATTGTCTTATAAAATGAATTAAATTATTTTGAAGATGAAAAAGAAGAATTTAA
AAATGACAAAAAACTACCTCAAAAACCTTAAAGAACAAGTTATATAAGCTAATAACATAA
AACAATAGCTCAAGAATAGTATTATAATCCTATTATTCTAGCTGATAATACTAAACACAG
AGAAAGGTAGATATAAAATTAAAGAAATTAGTAAAGAAATAACTCATTAGAGAATAAATT
CATAGAAAAATCCAATAATTAGCTAATATCAAATCGTAATCATATTAGATAGTAAAATTG
TAACAATGCTTCTTTTAATCTTATTAAAATTGACTCTTCCTAATAACTAGATATAGAAAA
TATATAAAATTCTTCAAGTGATAGCTGTCCTGAAGTTTATTAAAAGAATAAACTAACTAA
CATAAATTAACAATTAGATTTCAAATAAAAAAAAGATTTATTATAAATTTCAAATTTAAA
TACTATATAAAAAGAATAATCTATAGTTTAAAGCTAGAATTTAAATAGAAATATAAAGAT
AAAAAACTAGACTCCTTTACTTCCACCTATTCACCCTTAAAAATTAAAACAAGCACATTA
ATAAACTAATCATGATTTAAATAAAAATGAAATAAAAACAGATTTTATCCGTAAAAGCAG
AAGCAACTCTTTTACTGAAGAAAAAAATATTTTTAAAATGAACCTTGATAAAAGTTAAAG
AGTTTCTTCTAGTGAATTTAAGAATCTTCTTAATAATGTTAACTTTTAGTAAATACAAAA
AAATCTATCTAGAAACTAAAAATCTAAAACACAAACTAGTGAGTAAAATTATAATGTAAT
AGATGATAACTCAACAAATGGAGTAATTAAAAAATATCACTAAAAACACTAAAATGATAT
AAATTAATGTGCTTTTGATAGAGCTTAATACAATTAAAATATCAGATAAGAATAATAAAA
TAGTTTATTTATTTAAAGATACTAAATACCTTTAATAATTTCATAGCCTGAATTAGAATT
TATCTAAGAAAGATCGAATAATATTAAAAATTACCCTAATCAAGTAAGATAGTAAGTTAA
TTCTCAAGAATAACCCATTAATAATGGAAACATGCAATAAAATTTAGAAAATATAAGAGA
AATTAATGAAAGGTAAAAGTCCAAAGATGTTATAAGATTATAAAATCAAAATGTTAGAAC
TTAATAACAATAACAGCAACGTAATAATAACAATAATGAATAGACATATAACGATATTAT
TCAAAGAAGAAACTAAATAAATGCTTAGTAAGAAAATCTGAATGATTAATTTTAAAGTAG
GTAAAACACAATTAATTAAAATCCACCCCCAAGATTCATGATTGATAACATGTATAATTA
GTTTATAGAGTTTTAAAATCAGCTTAGATAGCATTAAGGAATTAAATCAGATAAATATGT
AAGCACAACTGTATATAAAAGTTCATAGTCTTAGAATCTTTCTTAAGATGCTAAATAGTG
CTCAATTTGTCTGTGCGAATTTGAGGATGAAGAGAAAATAAGTTTTTTGGCTTGCTTTCA
TCGTTTTCATAATGAATGCATTCACAAATGGTTTGAAACAAAATCAACTTGTCCTCTATG
CAAAAAAGATTAAAAAACATTAATAAAAGATGTTAATAAACTATTAGATGAATTTTGA

>TTHERM_00584700(protein)
MLNQNINLAQSISKEQISQQNQAQKNSKIPLIIRIANSSNNSTPVKLGSFQDLSNNEVIN
LCEQENIKQEINDFKPKKQIDCIVLQNELNYFEDEKEEFKNDKKLPQKPQRTSYISQQHK
TIAQEQYYNPIILADNTKHRERQIQNQRNQQRNNSLENKFIEKSNNQLISNRNHIRQQNC
NNASFNLIKIDSSQQLDIENIQNSSSDSCPEVYQKNKLTNINQQLDFKQKKDLLQISNLN
TIQKEQSIVQSQNLNRNIKIKNQTPLLPPIHPQKLKQAHQQTNHDLNKNEIKTDFIRKSR
SNSFTEEKNIFKMNLDKSQRVSSSEFKNLLNNVNFQQIQKNLSRNQKSKTQTSEQNYNVI
DDNSTNGVIKKYHQKHQNDINQCAFDRAQYNQNIRQEQQNSLFIQRYQIPLIISQPELEF
IQERSNNIKNYPNQVRQQVNSQEQPINNGNMQQNLENIREINERQKSKDVIRLQNQNVRT
QQQQQQRNNNNNEQTYNDIIQRRNQINAQQENLNDQFQSRQNTINQNPPPRFMIDNMYNQ
FIEFQNQLRQHQGIKSDKYVSTTVYKSSQSQNLSQDAKQCSICLCEFEDEEKISFLACFH
RFHNECIHKWFETKSTCPLCKKDQKTLIKDVNKLLDEF