Identifiers and Description

Gene Model Identifier

TTHERM_00649110

Standard Name

RPN12 (26S proteasome regulatory subunit N12)

Aliases

PreTt09225 | 94.m00143 | 3677.m00051

Description

RPN12 26S proteasome non-ATPase regulatory subunit 8

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• proteasome regulatory particle (IEA) | GO:0005838

Molecular Function

• calcium ion binding (IEA) | GO:0005509

Biological Process

• proteolysis (IEA) | GO:0006508

Domains

• ( PF03399 ) SAC3/GANP family

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_17868.1	9.99955252024689e-165
	Description: 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein (271 aa)
Oxytricha	Contig2043.0.g70	1.9998323414791308e-36
	Description: SAC3/GANP/Nin1/mts3/eIF-3 p25 family
DictyBase	DDB_G0272564	1.000137892321693e-31
	Description: psmD8-1 on chromosome: 2 position 2397564 to 2398683
WormBase	WBGene00004468	4.998021988471165e-24
	Description: locus:rpn-12 26S proteasome non-ATPase regulatory subunit 8 status:Confirmed UniProt:Q23449 protein_id:CAA93778.1
Stentor Coeruleus	SteCoe_16339	1.5628821893349888e-18
	Description: None
SGD	YFR052W	0.00000000000003999587784428659
	Description: RPN12 Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p

General Information

No Data fetched for General Information

Associated Literature

1. Ref:21637855: Xiong J, Yuan D, Fillingham JS, Garg J, Lu X, Chang Y, Liu Y, Fu C, Pearlman RE, Miao W (2011) Gene network landscape of the ciliate Tetrahymena thermophila. PloS one 6(5):e20124

Sequences

>TTHERM_00649110(coding)
ATGACTTTATAGTAAGCTTAACCTCTCTTAGCAGAATTTGAAACTTTAATAGCTTCTAAC
AGCAATGCTCCTAGAGTAGGCTAATTAATATCTTAGTTAAAGCGTATTATATTCCTCCTA
CCCAGTAATGATCCTCTCACTAAAACAAAAAATGAATAAGAGTTGATTGCATCCAGACGT
TTCCACGAATTGTGCATTTTACATAGCATTTAATCCAAAAACATTCAAAGCTTTGAGTCA
GCAATTAATTACTTAAGAGCTTATTACGAAAATTATCCTTAATTGCCAGCTTCTCAAGAT
AGAAATTAAATTATTGCATTGAATTTGTTATATCTTCTTTCTTTCAATAAAAACACTGAA
TACCATTCAGCTTTGGAGTTAGTTCCAGTTGAAGACTTGCACAATAATTAATTTATTCAA
TTCGTTACTGAATTAGAAAAGTAGTTGGCTATTGGTAACTACTCTGAAGCTCTCCTTTCT
AAAAACAAGTCTCCTCTTGCTCACTTCGATATATTCTTGGATAGAATCTTCGAAACTATT
AGATTTGAAACTGCTAGAAGTGCTGAAAAAGCCTATGAAAGTTTATCAATAAATGATGCA
ATTAAATTATTTAACCTTCAAAATGCCGATTAACTTAAAAGCTTTTCAGCTGAACAATCA
AAATAAGGAGAAGAACAAGGATTTTCTTGGGTTTTCGAAAATAATAGATTAGTCTTCCGT
CATAAAGATTCTGATAAAAAAGCATTATTCAACTCTGAATTTCTTATTTCAACAGCACTA
AGTTATGCTCATGAAATTGAAAAGATTGTTTGA

>TTHERM_00649110(gene)
ATGACTTTATAGTAAGCTTAACCTCTCTTAGCAGAATTTGAAACTTTAATAGCTTCTAAC
AGCAATGCTCCTAGAGTAGGCTAATTAATATCTTAGTTAAAGGTATTTCTTTTAAAAGAA
AAAATTAAGTTTAGTATCTATTTTAAGTGAATTTAATCAATCAATAAATCATTTACTTCT
AAATATCAAACATTTACTTTTATAAAAACAAATAGCGTATTATATTCCTCCTACCCAGTA
ATGATCCTCTCACTAAAACAAAAAATGAATAAGAGTTGATTGCATCCAGTAATGAACAGC
TTTAATTTTTAATCTCTAAATTATTTCATAAAACAGATAAAACGATAAATTGGGAGTATT
AAATATTTGTTTTAAAAAAGGACGTTTCCACGAATTGTGCATTTTACATAGCATTTAATC
CAAAAACATTCAAAGCTTTGAGTCAGCAATTAATTACTTAAGAGCTTATTACGAAAATTA
TCCTTAATTGCCAGCTTCTCAAGATAGAAATTAAATTATTGCATTGAATTTGTTATATCT
TCTTTCTTTCAATAAGTAATTCAATATAAATAAATTTTAAAATAGAATTAATAAATTTTA
TTATTAAATAGAAACACTGAATACCATTCAGCTTTGGAGTTAGTTCCAGTTGAAGACTTG
CACAATAATTAATTTATTCAATTCGTTACTGAATTAGAAAAGTAGTTGGCTATTGGTAAC
TACTCTGAAGCTCTCCTTTCTAAAAACAAGTCTCCTCTTGCTCACTTCGATATATTCTTG
GATAGAATCTTCGAAACTATTAGGTAACTTAGGATATTCTTTTGATTTTTAACTGATTAA
GAGATTTATTCTTTATATTTATAAAAAATGAATTTAAATGATTCATTAAATGTGTTAGAG
AGCGTTTGTTAATAGAGTTTATTAAGGGAATTATAACAAATAAATTAGTAGAAACAAATA
AAAGCTAAGAAATTAATATTAATTTTAAAAAAACAGATTTGAAACTGCTAGAAGTGCTGA
AAAAGCCTATGAAAGTTTATCAATAAATGATGCAATTAAATTATTTAACCTTCAAAATGC
CGATTAACTTAAAAGCTTTTCAGCTGAACAATCAAAATAAGGAGAAGTAAATTAACTATT
TGAATGAGCAATTAATTAATCAATAATTATTATTTTTTTTAAGGAACAAGGATTTTCTTG
GGTTTTCGAAAATAATAGATTAGTCTTCCGTCATAAAGATTCTGATAAAAAAGCATTATT
CAACTCTGAATTTCTTATTTCAACAGCACTAAGTTATGCTCATGAAATTGAAAAGATTGT
TTGA

>TTHERM_00649110(protein)
MTLQQAQPLLAEFETLIASNSNAPRVGQLISQLKRIIFLLPSNDPLTKTKNEQELIASRR
FHELCILHSIQSKNIQSFESAINYLRAYYENYPQLPASQDRNQIIALNLLYLLSFNKNTE
YHSALELVPVEDLHNNQFIQFVTELEKQLAIGNYSEALLSKNKSPLAHFDIFLDRIFETI
RFETARSAEKAYESLSINDAIKLFNLQNADQLKSFSAEQSKQGEEQGFSWVFENNRLVFR
HKDSDKKALFNSEFLISTALSYAHEIEKIV