Identifiers and Description

Gene Model Identifier

TTHERM_00825120

Standard Name

APC2 (Anaphase-Promoting Complex subunit 2)

Aliases

PreTt03976 | 142.m00073 | 3683.m00006

Description

cullin family protein; Anaphase-promoting complex subunit; promotes anaphase stage of mitosis

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cullin-RING ubiquitin ligase complex (IEA) | GO:0031461

Molecular Function

• ubiquitin protein ligase binding (IEA) | GO:0031625

Biological Process

• ubiquitin-dependent protein catabolic process (IEA) | GO:0006511

Domains

• ( PF00888 ) Cullin family
• ( PF05130 ) FlgN protein
• ( PF08672 ) Anaphase promoting complex (APC) subunit

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_18317.1	9.997093137033517e-262
	Description: hypothetical protein (843 aa)
Oxytricha	Contig9717.0.g94	6.001629673589058e-65
	Description: Cullin family
DictyBase	DDB_G0276377	9.997652352281279e-57
	Description: anapc2 on chromosome: 2 position 6676259 to 6679209
WormBase	WBGene00000143	2.998800627344286e-26
	Description: locus:apc-2 Anaphase-promoting complex subunit 2 status:Confirmed UniProt:P34514 protein_id:CCD64457.1
Stentor Coeruleus	SteCoe_33071	6.47023492564546e-26
	Description: None
SGD	YLR127C	0.0000000000008001317446409227
	Description: APC2 Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the catalytic core of the APC/C; has similarity to cullin Cdc53p

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00825120(coding)
ATGAATATATTTGAAATATTTTAGCACGATGAATACATTAAATAGAATCCAGAGATTCTA
TAATTTATTTACGAGATGTAAAAGGAATGGATAGATTTTAAGGGAATTATAGACAAATTG
TTTGTAGATTTAGAATACAATAAGCTTAAAGTTAGAGAGTAATGGAATGTTATAACCTAA
AAGAGATAGCCTTTAGTTAGAATAATTAGAGAGTACTATTTTAATAAATTTGAAAAGCAT
ATGCTTAAAGAATACAAAGATGAATTCTATTCTATACTGAACTTAGATAGAACGGAAAGC
GAGATAAATACTCAAAATTTTATTAAGGCACTACTTTCTCTTAATAAAAAATATGAAATT
CATATGAACTTCTTGCAAGATCTTGATTTAGAGTGTGAAGAAATGCAAAAAAAATAAAAT
TTATCAGTTAATTTATCTTAGATATTTAGCTTGAACCTTATTGAGATAGCAAATTTAAAT
GAAAATATATATGCTTTCTACAGAAAAGAGCTTATAAAATTTATGAAATTCGTATTAAAA
GAACACTCAAGCCAAATAGATCAATCGCTTATTACTGAATCTAGAAGAACTCTTATAGAA
AATGAACCTGAAAACTTTTAAGTTGATATCTACTAAAACTTTTTTTAAATATCTATTGAA
CTTGGATTCTACACAAAATCCTTATAAATATTGAATGAAGTGCTTGTAAAAGACATTCAA
GAGTATATAGAGAGCTAATAAGAGGCTCTATAAAATAATACTCCTATTTTAAAGAGGTGT
ATTTCATATTTTTCTAACTTTCACTTAAATTTTCTTCAAGTTATTGCTCAGAGTGTTAAA
ACAATATCGAGTAAAGAAATATAACTTGAATAACTATAAGGAGAGCTTAAAATTCTTTAA
GATTAGCTTTTGAGTAAAATATATGAGATCTATGGTAAAATATGTATATAAAATATTTTC
AGAATCGTGTTAGAGTTTCCAGAATCTTACGAACTTGTCTAAGAATTAAAAGAAATTGTT
GAAAAGACAAATCTAATATTTGACATGTGTGATTTTTTGTCTAGTTAAATTAGTTAAAGA
TTGCTAATACCTGGAGTTATAACAACAAACATTTTAAGCTAATACATAAATTGTCTTTAA
ATTCTTTAAATTATAGATCCAAAAGCTCTTATTTTGGAAAAAGTTACTTTTCCTATTAAA
AATTATCTGCTTAAAAGAAATGATACATTGAGATGCATTATTGAGCATTTAACTGATGAT
AAAAATACAAATAAATTAGTTCAAGAAAGACTAAAAATTCCTTCTAAATTTTAAAGTTAT
GATTTATCCTCAGATGAAGATGAAAACGAGGCAGAGAAATGGGAAGTTTAATATTTAAAC
TAAAAAAAATCGGAAGCAATTAAAATTAAGTATTAGGAGAGTGACTTACTTAGTATTTTG
GTTAACTTGTATGGATCACAAGAATCTTTCATTAGCGAGTATCAAAATATGCTTGCAGAA
AAAATGATGGGAACAAGAAATTTTGATATTGATGAAGAAATCAAAAATTTAGAACTTTTG
AAATTAAGATGTGGAGACTACAGCCTACAAACTTGCAACATTATAGTTAAGGATGTTAAG
GATTCAAAAAGAATTGACAACTTGATTCATTCATATAAAAAACCTATTAACCCTGAAGCA
TCTCTTAAGAATCCTCTACTTTCTATTGATTAACTTCACTGCATGTTTGTTTCTAAAGGA
TATTGGCCTATTAATTATGAAGTGGAAGGATTTCCTCTTCCTTCTTATTTAGAGCCACTC
TTCTAAGAATATGCAAAGAGATTTGAAAGAAATAGAGCTATGCGTAAGCTAATCTGGCAC
ACAAATCTTGGTCACGTTAATCTCACTCTTACATTTGATAATGGAGAATTTGAATTTAAG
TGTCTCCCAATTCATGCAATCTTAATTGGTTATTTTGATGAAACAAGATTTAATCCAGAA
AAAGGAGTTTCATCTGATTTTTTGAGTCAAGAAACATAGTTATCATAAAACTAAGTAAAG
TAGAAAATGGCTTTTTGGGTTCATAAAGGAGTTGTAAGAGAGTTTAAAAAGTAAGTGCCA
AAAGCTTAATCAAGTAATTTCAAGAATTTCTAAGGATACAATGAAGAAGGTGCAGAGAAC
GCTGATAATGATGTTAATGTATACTTTCCTGTTAGGGTTTATGAGAAATTTAGGGATTCA
GAAAATCTTATTTACTGTGAAGATGAAGAAAATGAAATGATTCTTAGAGATTAGTCTTAC
ATAGGATTTGAAAATACTCAATTTATAAAATATATCGAAAACTTGATAATTAGCATCTTA
AATAAAACCGGTCCAAGATCAGCTTCATAACTACATTGCTTGCTAAAGACACTCTATAAA
ACTGATTTAGAATATCCTGTTTAAGAAGATTAGATTAAAGATGTGCTTAGAAATATGAGC
CAAAAACATAAATTGATATTCAATGGTGAAGACTACTCATTACCTATTAGTTAAGAAAAA
GTTTAATGA

>TTHERM_00825120(gene)
ATGAATATATTTGAAATATTTTAGCACGATGAATACATTAAATAGAATCCAGAGATTCTA
TAATTTATTTACGAGATGTAAAAGGAATGGATAGATTTTAAGGGAATTATAGACAAATTG
TTTGTAGATTTAGAATACAATAGTAATTTATTTTTTACAACATTATCAAAAAGATTCATA
ATAGTTATCTGTGACTAAAGCAAAATAAAAATAATACTAAAATTTTGAGAAATTTAAACG
TATATTCATTTTTTAATATATTAGAGCTTAAAGTTAGAGAGTAATGGAATGTTATAACCT
AAAAGAGATAGCCTTTAGTTAGAATAATTAGAGAGTACTATTTTAGTAATTAGGATTTTA
TTTTAATGTAGCTTAAATAATAAAAATATTTTATTTATAGATAAATTTGAAAAGCATATG
CTTAAAGAATACAAAGATGAATTCTATTCTATACTGAACTTAGATAGAACGGAAAGCGAG
ATAAATACTCAAAATTTTATTAAGGCACTACTTTCTCTTAATAAAAAATATGAAATTCAT
ATGAACTTCTTGCAAGATCTTGATTTAGAGTGTGAAGAAATGCAAAAAAAATAAAATTTA
TCAGTTAATTTATCTTAGATATTTAGCTTGAACCTTATTGAGATAGCAAATTTAAATGAA
AATATATATGCTTTCTACAGGTATAGCTGAATTTTTATAATTTCTTTAATTTTCTTTTTC
TTTGAAAAGCAAAAAGTAGTTAAAAAATGTTAATTGATATAGCTTTTATTTATAATTAGA
AAAGAGCTTATAAAATTTATGAAATTCGTATTAAAAGAACACTCAAGCCAAATAGATCAA
TCGCTTATTACTGAATCTAGAAGAACTCTTATAGAAAATGAACCTGAAAACTTTTAAGTT
GATGTAAGTTTAAAAAAAAAATAAATTATCTAGAATTAAAATTTAAATTTACTTAATTAT
TAGATCTACTAAAACTTTTTTTAAATATCTATTGAACTTGGATTCTACACAAAATCCTTA
TAAATATTGAATGAAGTGCTTGTAAAAGACATTCAAGAGTATATAGAGAGCTAATAAGAG
GCTCTATAAAATAATACTCCTATTTTAAAGAGGTGTATTTCATATTTTTCTAACTTTCAC
TTAAATTTTCTTCAAGTTATTGCTCAGAGTGTTAAAACAATATCGAGTAAAGAAATATAA
CTTGAATAACTATAAGGAGAGCTTAAAATTCTTTAAGATTAGCTTTTGAGTAAAATATAT
GAGATCTATGGTAAAATATGTATATAAAATATTTTCAGAATCGTGTTAGAGTTTCCAGAA
TCTTACGAACTTGTCTAAGAATTAAAAGAAATTGTTGAAAAGACAAATCTAGTAAATAAA
TAATAAAAAAATTTATAATTTTATCAAACTTAAAAAACTAATTTTCTTAAAAATTAGATA
TTTGACATGTGTGATTTTTTGTCTAGTTAAATTAGTTAAAGATTGCTAATACCTGGAGTT
ATAACAACAAACATTTTAAGCTAATACATAAATTGTCTTTAAATTCTTTAAATTATAGAT
CCAAAAGCTCTTATTTTGGGTAATTTAACATATCTATTTGTCATAACTAAATAACTAACT
AAATAAACTTAAATTAATTTATAGAAAAAGTTACTTTTCCTATTAAAAATTATCTGCTTA
AAAGAAATGATACATTGAGATGCATTATTGAGCATTTAACTGATGATAAAAATACAAATA
AATTAGTTCAAGAAAGACTAAAAATTCCTTCTAAATTTTAAAGTTATGATTTATCCTCAG
ATGAAGATGAAAACGAGGCAGAGAAATGGGAAGTTTAATATTTAAACTAAAAAAAATCGG
AAGCAATTAGTATTAAATATTTTGTTTAAAGCTTGTTTTTAATTATTTATTGGTAAAGAA
ATTAAGTATTAGGAGAGTGACTTACTTAGTATTTTGGTTAACTTGTATGGATCACAAGAA
TCTTTCATTAGCGAGTATCAAAATATGCTTGCAGAAAAAATGATGGGAACAAGAAATTTT
GATATTGATGAAGAAATCAAAAATTTAGAACTTTTGAAATTAAGATGTGGAGACTACAGC
CTACAAGTAATTGATTGTTGTCAGCTAAAAATTTTTTAATGATAAAAATAAAATATAAAT
TAGACTTGCAACATTATAGTTAAGGATGTTAAGGATTCAAAAAGAATTGACAACTTGATT
CATTCATATAAAAAACCTATTAACCCTGAAGCATCTCTTAAGAATCCTCTACTTTCTATT
GATTAACTTCACTGCATGTTTGTTTCTAAAGGATATTGGCCTATTAATTATGAAGTGGAA
GGATTTCCTCTTCCTTCTTATTTAGAGCCACTCTTCTAAGAATATGCAAAGAGATTTGAA
AGAAATAGAGCTATGCGTAAGCTAATCTGGCACACAAATCTTGGTCACGTTAATCTCACT
CTTACATTTGATAATGGAGAATTTGAATTTAAGTGTCTCCCAATTCATGCAATCTTAATT
GGTTATTTTGATGAAACAAGTATAAAAAAGTTAAAGTTGTATTTAGAGTAAAAATATTTT
ATTATAAAATAAATAGGATTTAATCCAGAAAAAGGAGTTTCATCTGATTTTTTGAGTCAA
GAAACATAGTTATCATAAAACTAAGTAAAGTAGAAAATGGCTTTTTGGGTTCATAAAGGA
GTTGTAAGAGAGTTTAAAAAGTAAGTGCCAAAAGCTTAATCAAGTAATTTCAAGAATTTC
TAAGGATACAATGAAGAAGGTGCAGAGAACGCTGATAATGATGTTAATGTATACTTTCCT
GTTAGGGTTTATGAGAAATTTAGGGATTCAGAAAGTAAAGTGAGAAAATCTTATTCTTTA
ATAACAGTATTTTATATTTAAAATAGATCTTATTTACTGTGAAGATGAAGAAAATGAAAT
GATTCTTAGAGATTAGTCTTACATAGGATTTGAAAATACTCAATTTATAAAAGTATTTAT
TAAATTATTTATTCTATTCATTTAATTTTAACCCTATTTTATTCTTTTTATTTTTTAGTA
TATCGAAAACTTGATAATTAGCATCTTAAATAAAACCGGTCCAAGATCAGCTTCATAACT
ACATTGCTTGCTAAAGACACTCTATAAAACTGATTTAGAATATCCTGTTTAAGAAGATTA
GATTAAAGATGTGCTTAGAAATATGAGCCAAGTAATTCATTAAAAATTATTCAATTTTAA
ACTTTATAAATTTAAAATTTTTAACAATAAGAAACATAAATTGATATTCAATGGTGAAGA
CTACTCATTACCTATTAGTTAAGAAAAAGTTTAATGA

>TTHERM_00825120(protein)
MNIFEIFQHDEYIKQNPEILQFIYEMQKEWIDFKGIIDKLFVDLEYNKLKVREQWNVITQ
KRQPLVRIIREYYFNKFEKHMLKEYKDEFYSILNLDRTESEINTQNFIKALLSLNKKYEI
HMNFLQDLDLECEEMQKKQNLSVNLSQIFSLNLIEIANLNENIYAFYRKELIKFMKFVLK
EHSSQIDQSLITESRRTLIENEPENFQVDIYQNFFQISIELGFYTKSLQILNEVLVKDIQ
EYIESQQEALQNNTPILKRCISYFSNFHLNFLQVIAQSVKTISSKEIQLEQLQGELKILQ
DQLLSKIYEIYGKICIQNIFRIVLEFPESYELVQELKEIVEKTNLIFDMCDFLSSQISQR
LLIPGVITTNILSQYINCLQILQIIDPKALILEKVTFPIKNYLLKRNDTLRCIIEHLTDD
KNTNKLVQERLKIPSKFQSYDLSSDEDENEAEKWEVQYLNQKKSEAIKIKYQESDLLSIL
VNLYGSQESFISEYQNMLAEKMMGTRNFDIDEEIKNLELLKLRCGDYSLQTCNIIVKDVK
DSKRIDNLIHSYKKPINPEASLKNPLLSIDQLHCMFVSKGYWPINYEVEGFPLPSYLEPL
FQEYAKRFERNRAMRKLIWHTNLGHVNLTLTFDNGEFEFKCLPIHAILIGYFDETRFNPE
KGVSSDFLSQETQLSQNQVKQKMAFWVHKGVVREFKKQVPKAQSSNFKNFQGYNEEGAEN
ADNDVNVYFPVRVYEKFRDSENLIYCEDEENEMILRDQSYIGFENTQFIKYIENLIISIL
NKTGPRSASQLHCLLKTLYKTDLEYPVQEDQIKDVLRNMSQKHKLIFNGEDYSLPISQEK
VQ