Identifiers and Description

Gene Model Identifier

TTHERM_00833740

Standard Name

THD18 (Tetrahymena Histone Deacetylase 18)

Aliases

PreTt14157 | 144.m00120

Description

THD18 SIR2 family transcriptional regulator; transcriptional regulator- Sir2 family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Cellular Component

• acrosomal lumen (IEA) | GO:0043160
• host cell lysosome (IEA) | GO:0044187

Molecular Function

• carnitine O-acyltransferase activity (IEA) | GO:0016406

Biological Process

• dorsal/ventral axis specification (IEA) | GO:0009950
• obsolete DNA strand renaturation (IEA) | GO:0000733
• stilbene metabolic process (IEA) | GO:0009810

Domains

• ( PF02146 ) transcriptional regulator, Sir2 family

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_10210.1	9.997093137033517e-262
	Description: transcriptional regulator, Sir2 family protein (1549 aa)
Oxytricha	Contig21344.0.g34	1.9991517704232713e-32
	Description: Sir2 family
Stentor Coeruleus	SteCoe_30793	0.0000000000002543665647376923
	Description: None
DictyBase	DDB_G0270928	0.00000000019994075865167896
	Description: sir2E on chromosome: 1 position 3398987 to 3400602
SGD	YDR191W	0.0000000400154582995175
	Description: HST4 Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
WormBase	WBGene00004802	0.0000029996948234116693
	Description: locus:sir-2.3 NAD-dependent protein deacetylase sir-2.3 status:Partially_confirmed UniProt:Q20481 protein_id:CAA90547.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:18178773: Smith JJ, Torigoe SE, Maxson J, Fish LC, Wiley EA (2008) A class II histone deacetylase acts on newly synthesized histones in Tetrahymena. Eukaryotic cell 7(3):471-82

Sequences

>TTHERM_00833740(coding)
ATGGAATAAACTGATAATAGCAGCAAACAAACTTAGCAATAAGAAGAAACGAAAGATTGT
AGAAACTGCTCTTATGAAGAAACCATGAAAACGATTGAAGAGACAAGACTAAATTGTTAA
AGGACAATGCAAATTTGCAACTAATCAATATAAACTATTGGAGAATCTATCAAAACAGCC
AATGAAGCAAAATAAAATATCGATGGCTTTTTCGATTAGTACAATTAAGCTATGAACAGC
TTGAGCGAGAAAATTTCTGGATCGTTCTCAGGAATGAGTCGTTGTTTTTTAAAAAATGAG
AACACTGATAAGTAATTTGAAGATTCAAGATAAATAACAGTTAAAGAAGGTGCATAATTT
TTCAAAGACAAGAAAAAAGTTGTTTTTTTGACAGGAGCTGGTATTTCAGTAGCAAGTGGA
ATTCCAACATTCAAAGGAGTTGGTGCTGCACCTCTTTTTGAAAAGGACGGAGTTACTTAT
CAAAATGAACAAATTTCTACTTATAATTTTATGAAAAACAAACCAGATATTTTTTGGGAA
AGAAATTTGATATTCTTAGGAGGTTAATTGGGAAAGAAATACAATGTATCTCACTTAAAG
ATTCAATAATTAGTCAATTAGTATAAATAAATCAAGACATCTTAACTTGGGAAGCAAAAT
GCTTATCAACCCTAAGCAGTAATTGTGACATAAAATACAGATGGTCTTCATTGCTAAGCT
TTTAATGAGTTAAATCCCAGAGAAACAAATTACATGAACAAAGATGATCCTCAATATGGA
TTTTGCCCTGATGTCTTTGAAGTTCATGGCAGTAAAACTTTCCTTAGATGTGATAATTAA
GAATGCAAAGATTATGACAAAAAGTTTTTGTACCCACAAAAATATGATTCTTACAAAGAC
TTCATTTGCGAAACTTGTAAAACCTAAGCTAGACCAAATGTATTGTACTTTGATGAATCT
TATGATGAAAAAAATTATAGGATAAACACTTTGAATGAATTAACTTCTGACATGGATCTA
TTGATATCTATAGGAACATAATTAGACACAGGATATGCTGCTTAAACTGTCAGTAATGCA
GTTCAATAAAAGATTCCAGTCATAGAAATATCTTTAACACCTGTCATATAAAAAGGAGGT
CTAACTCTGAAAGGAAAAGCAGAAGAAGTTGTACCTCAATTATGTGATTTAGTTATGGAA
TTAAATAAATAATTATTACCCACACAACAAAAAGTAGCAAATAAATCAATTGCTTAGAAA
AGTTAAAATCTACTAAAAGATTAAAATAATAAAAGCAATAGCTGTTTATAATCTACAAAT
ACCAGTAAATCTTCCATTTCTAATAAAGTATCAACTAATTCTGCTTAATCTGCAGTAAAA
ACTCTTAATTAAAACCAAGATAATACCTAAACTAATTAAAAACCATAAGTAAAATAAGTC
AGTTTTAGAAAGCCAAATATTAAAGTTGGTCTAAACACAAAGGTAAAAAAGTGA

>TTHERM_00833740(gene)
ATGGAATAAACTGATAATAGCAGCAAACAAACTTAGCAATAAGAAGAAACGAAAGATTGT
AGAAACTGCTCTTATGAAGAAACCATGAAAACGATTGAAGAGACAAGACTAAATTGTTAA
AGGACAATGCAAATTTGCAACTAATCAATATAAACTATTGGAGAATCTATCAAAACAGCC
AATGAAGCAAAATAAAATATCGATGGCTTTTTCGATTAGTACAATTAAGCTATGAACAGC
TTGAGCGAGAAAATTTCTGGATCGTTCTCAGGAATGAGTCGTTGTTTTTTGTAAGTAAAT
CATTCGCTTATTTAAACAACTAAATTTTTTTTTTTAACCAAAAAGAAAAAATGAGAACAC
TGATAAGTAATTTGAAGATTCAAGATAAATAACAGTTAAAGAAGGTGCATAATTTTTCAA
AGACAAGAAAAAAGTTGTTTTTTTGACAGGAGCTGGTATTTCAGTAGCAAGTGGAATTCC
AACATTCAAAGGAGTTGGTGCTGCACCTCTTTTTGAAAAGGACGGAGTTACTTATCAAAA
TGAACAAATTTCTACTTATAATTTTATGAAAAACAAACCAGATATTTTTTGGGAAAGAAA
TTTGATATTCTTAGGAGGTTAATTGGGAAAGAAATACAATGTATCTCACTTAAAGATTCA
ATAATTAGTCAATTAGTATAAATAAATCAAGACATCTTAACTTGGGAAGCAAAATGCTTA
TCAACCCTAAGCAGTAATTGTGACATAAAATACAGATGGTCTTCATTGCTAAGCTTTTAA
TGAGTTAAATCCCAGAGAAACAAATTACATGAACAAAGATGATCCTCAATATGGATTTTG
CCCTGATGTCTTTGAAGTTCATGGCAGTAAAACTTTCCTTAGATGTGATAATTAAGAATG
CAAAGATTATGACAAAAAGTTTTTGTACCCACAAAAATATGATTCTTACAAAGACTTCAT
TTGCGAAACTTGTAAAACCTAAGCTAGACCAAATGTATTGTACTTTGATGAATCTTATGA
TGAAAAAAATTATAGGATAAACACTTTGAATGAATTAACTTCTGACATGGATCTATTGAT
ATCTATAGGAACATAATTAGACACAGGATATGCTGCTTAAACTGTCAGTAATGCAGTTCA
ATAAAAGATTCCAGTCATAGAAATATCTTTAACACCTGTCATATAAAAAGGAGGTCTAAC
TCTGAAAGGAAAAGCAGAAGAAGTTGTACCTCAATTATGTGATTTAGTTATGGAATTAAA
TAAATAATTATTACCCACACAACAAAAAGTAGCAAATAAATCAATTGCTTAGAAAAGTTA
AAATCTACTAAAAGATTAAAATAATAAAAGCAATAGCTGTTTATAATCTACAAATACCAG
TAAATCTTCCATTTCTAATAAAGTATCAACTAATTCTGCTTAATCTGCAGTAAAAACTCT
TAATTAAAACCAAGATAATACCTAAACTAATTAAAAACCATAAGTAAAATAAGTCAGTTT
TAGAAAGCCAAATATTAAAGTTGGTCTAAACACAAAGGTAAAAAAGTGA

>TTHERM_00833740(protein)
MEQTDNSSKQTQQQEETKDCRNCSYEETMKTIEETRLNCQRTMQICNQSIQTIGESIKTA
NEAKQNIDGFFDQYNQAMNSLSEKISGSFSGMSRCFLKNENTDKQFEDSRQITVKEGAQF
FKDKKKVVFLTGAGISVASGIPTFKGVGAAPLFEKDGVTYQNEQISTYNFMKNKPDIFWE
RNLIFLGGQLGKKYNVSHLKIQQLVNQYKQIKTSQLGKQNAYQPQAVIVTQNTDGLHCQA
FNELNPRETNYMNKDDPQYGFCPDVFEVHGSKTFLRCDNQECKDYDKKFLYPQKYDSYKD
FICETCKTQARPNVLYFDESYDEKNYRINTLNELTSDMDLLISIGTQLDTGYAAQTVSNA
VQQKIPVIEISLTPVIQKGGLTLKGKAEEVVPQLCDLVMELNKQLLPTQQKVANKSIAQK
SQNLLKDQNNKSNSCLQSTNTSKSSISNKVSTNSAQSAVKTLNQNQDNTQTNQKPQVKQV
SFRKPNIKVGLNTKVKK