Identifiers and Description

Gene Model Identifier

TTHERM_01123840

Standard Name

HIB1 (HydroxyIsoButyrate dehydrogenase 1)

Aliases

PreTt03038 | 244.m00024 | 3834.m00386

Description

HIB1 3-hydroxyisobutyrate dehydrogenase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• phosphogluconate dehydrogenase (decarboxylating) activity (IEA) | GO:0004616

Biological Process

• obsolete oxidation-reduction process (IEA) | GO:0055114
• pentose-phosphate shunt (IEA) | GO:0006098

Domains

• ( PF00107 ) oxidoreductase, zinc-binding dehydrogenase family
• ( PF02254 ) TrkA-N domain
• ( PF03446 ) NAD binding domain of 6-phosphogluconate
• ( PF03807 ) NADP oxidoreductase coenzyme F420-dependent
• ( TIGR00112 ) pyrroline-5-carboxylate reductase
• ( TIGR00745 ) 2-dehydropantoate 2-reductase
• ( TIGR00872 ) 6-phosphogluconate dehydrogenase (decarboxylating)
• ( TIGR01505 ) 2-hydroxy-3-oxopropionate reductase
• ( TIGR01692 ) 3-hydroxyisobutyrate dehydrogenase
• ( TIGR03026 ) nucleotide sugar dehydrogenase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_15858.1	9.997093137033517e-262
	Description: 3-hydroxyisobutyrate dehydrogenase (317 aa)
DictyBase	DDB_G0292566	2.0005330067840427e-93
	Description: hibA on chromosome: 6 position 1891263 to 1892228
Oxytricha	Contig18515.0.g30	9.996584278131743e-91
	Description: NAD binding domain of 6-phosphogluconate dehydrogenase
WormBase	WBGene00007122	9.999030951775615e-88
	Description: Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial status:Confirmed UniProt:Q9XTI0 protein_id:CAB03798.1
Stentor Coeruleus	SteCoe_386	0.0000000000002543665647376923
	Description: None
SGD	YGR256W	0.000030009396760408108
	Description: GND2 6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01123840(coding)
ATGAGAAGAATCGCTCGTTCCTTAAATAACTCCTAATATCTCAGAGCAGAAACTGTTGGT
TTCATCGGTTTGGGAAATATGGGTGGCCCTATGGCTCTTAATTTAGCTAGAAAAGGTGGC
TTTGAAGTTATTGCTTTTGATGTAAATAAAGATTCTTTGAAGAAATATGCTAAAGAAGGT
TTAGCTGTTTGTGAAGATGTTACAGTATTGGCACGTAAAGCTAACAAGTTCGTTACAATG
CTTCCTAACTCTTCCCATGTTAGCAGTGTCTTAGAAGGGGAAAATGGATTATTCTAAAAG
AGTGCAAAAAATAGTTTGTTTATTGATTCATCTACAATTTCTTATCATGCTGCTATAAAG
ATCTACGAAAATGCTAAGAAGGTCAATCAACGTTACATTGATGCTCCTGTTAGTGGTGGT
GTTGGTGCTGCAACAGCTGGTACTCTCACTTTTATGGTTGGTGCTGAAAATAAGGAACTC
TTCTAAGAATGCAAAAATCTTCTTTAACACATGGGTAAAAATATCGCCAACTGTGAAAAA
CCTGGTGCTGGATCTATTGCTAAAATTTGCAATAACATGGCTCTTGGTATTGAAATGATA
GCCGTTGCAGAAGCTATCTCCTTGGGCAAAAAGCTTGGTATCGACCCTAAAGTTCTTTCA
TCAATCATGAATACTGCATCTGGTAGATGCTGGAGTAGTGAAGTCTATAACCCTTGCCCT
GGCGTATTAGAAAATGTTCCTGCTTCTAAGGGTTATGAAGGAGGTTTTGCTTGTGAACTT
ATGCTTAAGGATTTAGGATTAGCTGCTGATGCTGCAAAACAAGCTTCTGCTGATGTTCCT
CTTGGTAACCATGCAAAAGATATTTACTAAAAATTGGTTGAATTGGGACTTAATCGTAAA
GATTTTGCTATCGTTTATGATGTCCTCTTAAATAATAAACTTAAATAATGA

>TTHERM_01123840(gene)
ATGAGAAGAATCGCTCGTTCCTTAAATAACTCCTAATATCTCAGAGCAGAAACTGTTGGT
TTCATCGGTTTGGGAAATATGGGTGGCCCTATGGCTCTTAATTTAGCTAGAAAAGGTGGC
TTTGAAGTTATTGCTTTTGATGTAAATAAAGATTCTTTGAAGAAATATGCTAAAGAAGGT
TTAGCTGTTTGTGAAGATGTTACAGTATTGGCACGTAAAGCTAACAAGTTCGTTACAATG
CTTCCTAACTCTTCCCATGTTAGCAGTGTCTTAGAAGGGGAAAATGGATTATTCTAAAAG
AGTGCAAAAAATAGTTTGTTTATTGATTCATCTACAATTTCTTATCATGCTGCTATAAAG
ATCTACGAAAATGCTAAGAAGGTCAATCAACGTTACATTGATGCTCCTGTTAGTGGTGGT
GTTGGTGCTGCAACAGCTGGTACTCTCACTTTTATGGTTGGTGCTGAAAATAAGGAACTC
TTCTAAGAATGCAAAAATCTTCTTTAACACATGGGTAAAAATATCGCCAACTGTGAAAAA
CCTGGTGCTGGATCTATTGCTAAAATTTGCAATAACATGGCTCTTGGTATTGAAATGATA
GCCGTTGCAGAAGCTATCTCCTTGGGCAAAAAGCTTGGTATCGACCCTAAAGTAAACAAT
TTTATATTTATATTAGTCATTAAAATATTCTAAAAGACATAAATAAAATTATTAGTAGAA
CAAATATTATGAGAATTAAATTATGCTATCATTTTCAATCAAAAAAATTATTTTTTTTAA
AAAACTGTTATAAATAAATATATTTTTTGTCTTTTTATTTATTTATTTATTAATTTCCAT
TTTTAAAATAAATAAACTAATAAATAATAAAATAGGTTCTTTCATCAATCATGAATACTG
CATCTGGTAGATGCTGGAGTAGTGAAGTCTATAACCCTTGCCCTGGCGTATTAGAAAATG
TTCCTGCTTCTAAGGGTTATGAAGGAGGTTTTGCTTGTGAACTTATGCTTAAGGATTTAG
GATTAGCTGCTGATGCTGCAAAACAAGCTTCTGCTGATGTTCCTCTTGGTAACCATGCAA
AAGATATTTACTAAAAATTGGTTGAATTGGGACTTAATCGTAAAGATTTTGCTATCGTTT
ATGATGTCCTCTTAAATAATAAACTTAAATAATGA

>TTHERM_01123840(protein)
MRRIARSLNNSQYLRAETVGFIGLGNMGGPMALNLARKGGFEVIAFDVNKDSLKKYAKEG
LAVCEDVTVLARKANKFVTMLPNSSHVSSVLEGENGLFQKSAKNSLFIDSSTISYHAAIK
IYENAKKVNQRYIDAPVSGGVGAATAGTLTFMVGAENKELFQECKNLLQHMGKNIANCEK
PGAGSIAKICNNMALGIEMIAVAEAISLGKKLGIDPKVLSSIMNTASGRCWSSEVYNPCP
GVLENVPASKGYEGGFACELMLKDLGLAADAAKQASADVPLGNHAKDIYQKLVELGLNRK
DFAIVYDVLLNNKLKQ