Identifiers and Description

Gene Model Identifier

TTHERM_01141570

Standard Name

ICL1 (IsoCitrate Lyase 1)

Aliases

PreTt20062 | 251.m00042 | 3821.m00564

Description

ICL1 isocitrate lyase; Isocitrate lyase family protein; similar domain structure to yeast isocitrate lyase 1 (ICL1)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Molecular Function

• polyketide synthase activity (IEA) | GO:0016218

Biological Process

• creatine biosynthetic process (IEA) | GO:0006601

Domains

No Data fetched for Domains

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_20883.1	9.997093137033517e-262
	Description: hypothetical protein (504 aa)
Oxytricha	Contig20680.0.g93	9.997093137033517e-262
	Description: Isocitrate lyase family
SGD	YER065C	2.0007442334946695e-153
	Description: ICL1 Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose
WormBase	WBGene00001564	2.998830401637127e-79
	Description: locus:icl-1 status:Confirmed UniProt:Q8IA71 protein_id:CCD63239.1
DictyBase	DDB_G0273017	5.998439611888618e-47
	Description: DDB_G0273017 on chromosome: 2 position 2236569 to 2237975

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01141570(coding)
ATGGACGTTGAAGGAAAGAGACTCTAAGAAATCACTGCTGAAATCCAAAAATGGTGGACT
AACTCTCGTTGGGAAAATGTTGAAAGACCCTACTAAGCTTAAGATGTTGCCCGTTTAAGA
CCCACCATCCCCATGGACTACCCCTCCAACTACTAATCCAAGAAGATGTGGAAACTCTTG
AAGGAAGCCCAAGCCAACAAGGGATTCCACCACACTTTCGGTGCCTTAGACCCCGTTCAA
GTTATCAACTTATCCAAGTACTTGAGAACTGTCTACGTCTCTGGATGGTAATGCTCTGCC
ACTGCCTCCACTACTAATGAACCTGGTCCAGATTTTGCTGATTACCCTGCCAACACTGTC
CCCAACAAAGTTGACCAACTCTTCAAGGCTTAACTTTTACAAGACAGAATCCAAAATGAA
CAAAGAGCTCATTTGACCCCTGAATAAAGAGCTAAGACTCCCAGAGTTGACTACCTTGCT
CCTATGATTGCTGATGCTGATGCTGGTTTCGGTGGTATTACTTCAACCATGAAGTTAATT
AAGTTATTCATTGAAGCTGGTGCTGCTGGTATCCATCTTGAAGATTAAAGACCTGGTACC
AAGAAATGTGGTCACATGAGTGGTAAGGTCGTTGTCTCCACTCGCGAACACGTCAACAGA
TTAATTGCTTGCAGACTCCAAGCTGATATTATGGGAACTGATTTAATTATCCTCGCCAGA
ACTGATGCTTTATCTGCTAGACTTATTGACTCCAACTGTGACCCCGTTGACCACCCCTTC
ATCCTTGGTCTTTGCCCTGATGGTAAGGAAAGAACTTTCCCTAATGCAGGTCTTGAAGCT
ATCAAGGCTAAGTTCACTGGTGCTAAGGTCCAAGAAGTCACCAAGCTCTGGCTCTCTAAG
TGTTACGATCTTTCCCTCACTCAAGCCCACGAATACGCTAGAACTCTCGGTTTTGACTTC
CAATTCGACTGGGAAGCTCTCCGTTCATCTGAAGGTTTCTACTCCATTGACGGTTGTGTT
GAATTATGTGCTGCTCGTGCTAAGTAATATTTAAGATATGCTGATATGGTTTGGATGGAA
ACTCCTACTCCCTCTTTGGAAGTTGCTACTAAGTTCTCTACCTTGGTAAAGAATAACCAT
CCCACCAAATTATTGGCTTACAACCTTTCCCCCTCTTTCAACTGGTCTGCTTTCAACATG
TCCAATGCTCAAATCCAATCTTTCTGTGCTGACCTTGGTAGACTCGGATACACCTGGTAA
TTCATTACTTTAGCTGGTTTCCACTTGAATGCTCTCAAGTCTGAAAAGCTCTCTAAGGAT
CTTGCTGCCCGTGGTATGCTCGCCTACGTCGAAACTGTCCAAAGAAAGGAAGAAAAGCAC
AAAGTCGACCAACTCACCCACCAAAAATGGTCTGGTGCTAACTACGTTGATGCTTGCCAA
GCCCTTGTTCAACCCGAATCTCAAACCTTAGCCTCCTCCAAAGACTCTACTGAAAACTAA
TTCAAGCATTGA

>TTHERM_01141570(gene)
ATGGACGTTGAAGGAAAGAGACTCTAAGAAATCACTGCTGAAATCCAAAAATGGTGGACT
AACTCTCGTTGGGAAAATGTTGAAAGACCCTACTAAGCTTAAGATGTTGCCCGTTTAAGA
CCCACCATCCCCATGGACTACCCCTCCAACTACTAATCCAAGAAGATGTGGAAACTCTTG
AAGGAAGCCCAAGCCAACAAGGGATTCCACCACACTTTCGGTGCCTTAGACCCCGTTCAA
GTTATCAACTTATCCAAGTACTTGAGAACTGTCTACGTCTCTGGATGGTAATGCTCTGCC
ACTGCCTCCACTACTAATGAACCTGGTCCAGATTTTGCTGATTACCCTGCCAACACTGTC
CCCAACAAAGTTGACCAACTCTTCAAGGCTTAACTTTTACAAGACAGAATCCAAAATGAA
CAAAGAGCTCATTTGACCCCTGAATAAAGAGCTAAGACTCCCAGAGTTGACTACCTTGCT
CCTATGATTGCTGATGCTGATGCTGGTTTCGGTGGTATTACTTCAACCATGAAGTTAATT
AAGTTATTCATTGAAGCTGGTGCTGCTGGTATCCATCTTGAAGATTAAAGACCTGGTACC
AAGAAATGTGGTCACATGAGTGGTAAGGTCGTTGTCTCCACTCGCGAACACGTCAACAGA
TTAATTGCTTGCAGACTCCAAGCTGATATTATGGGAACTGATTTAATTATCCTCGCCAGA
ACTGATGCTTTATCTGCTAGACTTATTGACTCCAACTGTGACCCCGTTGACCACCCCTTC
ATCCTTGGTCTTTGCCCTGATGGTAAGGAAAGAACTTTCCCTAATGCAGGTCTTGAAGCT
ATCAAGGCTAAGTTCACTGGTGCTAAGGTCCAAGAAGTCACCAAGCTCTGGCTCTCTAAG
TGTTACGATCTTTCCCTCACTCAAGCCCACGAATACGCTAGAACTCTCGGTTTTGACTTC
CAATTCGACTGGGAAGCTCTCCGTTCATCTGAAGGTTTCTACTCCATTGACGGTTGTGTT
GAATTATGTGCTGCTCGTGCTAAGTAATATTTAAGATATGCTGATATGGTTTGGATGGAA
ACTCCTACTCCCTCTTTGGAAGTTGCTACTAAGTTCTCTACCTTGGTAAAGAATAACCAT
CCCACCAAATTATTGGCTTACAACCTTTCCCCCTCTTTCAACTGGTCTGCTTTCAACATG
TCCAATGCTCAAATCCAATCTTTCTGTGCTGACCTTGGTAGACTCGGATACACCTGGTAA
TTCATTACTTTAGCTGGTTTCCACTTGAATGCTCTCAAGTCTGAAAAGCTCTCTAAGGAT
CTTGCTGCCCGTGGTATGCTCGCCTACGTCGAAACTGTCCAAAGAAAGGAAGAAAAGCAC
AAAGTCGACCAACTCACCCACCAAAAGTAATTATAAAAACATTTTTATCTATATAAAATA
AAAAAAAATGGCTCTGATAAGTAGGTATAAATAAAATATTCAAATAATAGAGATAGACAA
TCATATGATCTTTTAATAGCAATTTATCAATGTTTAATATATCAAAAAAAGCAATAGAAC
AAACAAAAGCATTCATTCGATCTATTAAAAAATAAAAAGAATATTTTATTTATACACCTC
TATAATAAATTGCTAATTTTATTTACTCATTCATTTATTAAAATTAATTTGTATTAAATA
GATGGTCTGGTGCTAACTACGTTGATGCTTGCCAAGCCCTTGTTCAACCCGAATCTCAAA
CCTTAGCCTCCTCCAAAGACTCTACTGAAAACTAATTCAAGCATTGA

>TTHERM_01141570(protein)
MDVEGKRLQEITAEIQKWWTNSRWENVERPYQAQDVARLRPTIPMDYPSNYQSKKMWKLL
KEAQANKGFHHTFGALDPVQVINLSKYLRTVYVSGWQCSATASTTNEPGPDFADYPANTV
PNKVDQLFKAQLLQDRIQNEQRAHLTPEQRAKTPRVDYLAPMIADADAGFGGITSTMKLI
KLFIEAGAAGIHLEDQRPGTKKCGHMSGKVVVSTREHVNRLIACRLQADIMGTDLIILAR
TDALSARLIDSNCDPVDHPFILGLCPDGKERTFPNAGLEAIKAKFTGAKVQEVTKLWLSK
CYDLSLTQAHEYARTLGFDFQFDWEALRSSEGFYSIDGCVELCAARAKQYLRYADMVWME
TPTPSLEVATKFSTLVKNNHPTKLLAYNLSPSFNWSAFNMSNAQIQSFCADLGRLGYTWQ
FITLAGFHLNALKSEKLSKDLAARGMLAYVETVQRKEEKHKVDQLTHQKWSGANYVDACQ
ALVQPESQTLASSKDSTENQFKH