Identifiers and Description

Gene Model Identifier

TTHERM_00011740

Standard Name

MCM7 (DNA replication licensing factor MCM7)

Aliases

PreTt11780 | 1.m00828

Description

MCM7 MCM2/3/5 family protein; Component of the Mcm2-7 complex involved in DNA replication

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• ATP hydrolysis activity (IEA) | GO:0016887
• DNA binding (IEA) | GO:0003677

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF00493 ) MCM2/3/5 family
• ( PF01078 ) Magnesium chelatase, subunit ChlI
• ( PF03413 ) Peptidase propeptide and YPEB domain
• ( PF05316 ) Mitochondrial ribosomal protein (VAR1)
• ( PF07726 ) ATPase family associated with various
• ( PF07728 ) ATPase family associated with various
• ( PF08573 ) DNA repair protein SAE2
• ( TIGR00166 ) ribosomal protein S6
• ( TIGR00368 ) Mg chelatase homolog
• ( TIGR02880 ) CbbX protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_02773.1	9.997093137033517e-262
	Description: MCM2/3/5 family protein (1371 aa)

General Information

No.	Gene Name(s)	Paragraph Text
141	MCM7	The MCM7 gene is incorrectly annotated - its actual ID is TTHERM_000011759.

Associated Literature

1. Ref:31815942: Tian M, Loidl J (2019) An MCM family protein promotes interhomolog recombination by preventing precocious intersister repair of meiotic DSBs. PLoS genetics 15(12):e1008514

Sequences

>TTHERM_00011740(coding)
ATGATTAATAAAAGGACAAGCTTCACCTCTAAGATGTTAAGCGGGAGGAAAAATTCTTGT
TAATCAACAACTTCTTCAGCAGAATCTCACAACTTTAGGAGCACAAATGATATAGATCAT
AAAGTGCATCTGATAGAAAAATCACCCAATAAATACAAGTTGATAACTGAAAACAAACAA
ACACAAAATAAGAGTCAGCTAAGAAGACTGAACAACTTGAAGCTACTAGGATTTATAAAG
GTTAAGGAATGCGGAGGTGCAGATCTTAAAAATGAATAAGAATAATAGCTACAATTTAAA
AAAACATTCAAAGTGAATTAAAAAGGATTAATTTTTGATAATCATTAATACTTTCTTAAC
CTTAATGCGGTGATAAGCAACAATCACTTGATAAGATAATCTAGTCCAGTAGAAAGGTTA
AAGGCTAATCTTTACGATGAAGAGAGAGTTCCTTAAATTAGCTAATATATTAAGACTAAT
AGTACCAATTTTTAAGATACTCCTCTGAGTTAAACTAATTAATATAATCTTATTTCCTGC
TCAAATGGTAGTAACAATAACAAAAAGAAAGCAGCTTTTCGTCGTCGTAGCTGCTATTGC
AACTAAACTGGTAAGTAAAGCCAAAAAGCTTAAAAAATAGACTTCTAATTGCCTACAACC
TTCATTAAAAATAGAATTTACTAGCGTATGAAAAGAAAGTAGGAAATGAAAATGAATTTG
AATGAAAAAGATTTGATTATTTAGAATTTAAATCGTACATTCGACATTCAAGAAAAGAAT
TCTGCTCGCGGAAGTCTGCTAAATAGTCCTAATATCATGAATATGCAGCAAACATTTAAC
TTTTTAGACACTCCTATGTCAGGAAGAGTTATGAATACACCTAGCGCAAGCAATAGGTAT
AACAATTAACACCACGTCCATTCAAGCTAAGCTTAAAGAAGCTAATTTTCTTACATGACA
TCACCAAAGAATGGCTAACAACATTCTAATTAAGGAACTGCCACTCATAGTAAGAAAGAT
GATAACACATTAAAAAATGCTCAAAGTCCTGTAAATCGTAATCCTAACAGCAAGCCTACA
TTCGCAGAAACTATTGAATATATCAAAGAAGAACAGAGTCAACAGTAAAATGTTACTCCT
TAATCTAAATAAGAAAAAAAATCACCTCAAAAAACAAACTCATAAATCTCTAGCAAAGAG
TTGGAGTTATCTTTAAATAAAGTAGTTCATCGTAAAAATATTTCTAGCAATAAAAATTCC
CCTAAAAATAATCATGTTTCTGCTTCTCCTAATCGCTAAACTCCTGTAAGCAGCAGCAAG
AAGAGTAGCATGTTCAACTACTTTGGCGTAGGAGGAAAAACCTTAAAGGACGACTCACAC
TAAAAATAATAATATGAAAGCATTTATCCAGAACAAGTGGAGAAAAGAAAAAAATGGATC
ACAAAGCTTCGTATTGCTACCAAATTAGTTGGTTTTTAAGAAAAACAAAGAAAAAAATCT
ATGTTGTACTAGTAAGATTATTACAAGGCACTTGAAGAAGTTGCAAATAACGAGGTTGAG
CTTGAAAATTTAGAATAAAATGATGAATTTAATCACAATAATTAGGAGAAAAAAAACATT
TTAATTAGAAAAGTCAAATAAAGCAATATCAATAAAAATAATTTTATGCTAAATTAAATA
GTAAAGCAACACAACTTAAAATTCAATTCCACAATAGGCTCTTTTCTTGATATGCGCACT
AAAAGTCAAAATTGTCTTCTTCCTTCAACGAATTCTTCCATCTTTGCCTTCCCTTAGAAA
TTGAGTAGAAGACATTTAGTAAGCCCATTCAATTACGACAGCAAATCGGAATATATTATC
CATAAAAAGGATAGTAAAATAGGTGCTTATCTGTAGCCCTTCCCAGTAATTCTTTCGCCA
TCTCCAAGCAAATAAGATCATAGTAAAAAATCTCAGAGCAAAACAAACTAGCTTTTCTAA
TCATCTTTTGTTACAAATACTGATAAAAAAAATAAAAAATCGAATGAGATAATCAATAGA
AGTAGTTCTCATAAAAAAATTAACTCATCAACAATGACAGAACTTGGTAAAGGAAATTAA
AATAAAAATCATTTTAGTAAGAATTATTTGCTCATGCCAAAAAGTGCGAAATCTGGTTAA
ATTTAATTAAGTAATTCATCAAATAGCATAGAAGAATTGAATGCTACTGAAAATAATCTC
TAGAATGAAGCAAGTAAATCTAGTCTAGGATTAAAATCTAATAACGATAAAGACAGCCAC
TAAAATAGCCAGCAAAATATAGTAAGTCTTGAATAGCTCGGAAGATATGAAACATATTTT
GCAAAAAAGCCAGATTAAAAAAATTAAAAAGTTAACAATTAATCAAAAACTTAGCAAAAA
TTCTAGCTGCTCATAAACAATTAGTCGATACAAAACTCTTATTTAATAAAAAGCAATTTA
AAAAATTCAAATTCTATAAATCACTTAAGTAAAACCATAAATTTTGGTTAAATTAATCAA
AAAACAGCTTCATAGCCTGATTTACTTCAAAGTACTTTCAAGCACGACACATCAAATGTA
TCATCTAACAATTTGACCATAAAAAGTCCAAATATTTAAAACAGAAGACCCAGCTATCTT
TAGCAAAAATTTGAAAGTAAGACCCATCGTAAATCAATCCTACAGAGCTATTTGGTTTGA

>TTHERM_00011740(gene)
ATGATTAATAAAAGGACAAGCTTCACCTCTAAGATGTTAAGCGGGAGGAAAAATTCTTGT
TAATCAACAACTTCTTCAGCAGAATCTCACAACTTTAGGAGCACAAATGATGTAATAAAT
ACATTATTAATTAATAAATATAGTTTGATATTGTAAATATGATGGTAAAGCAACCTTTTT
ATAAAAAAACTAGATAGATCATAAAGTGCATCTGATAGAAAAATCACCCAATAAATACAA
GTTGATAACTGAAAGTAAAATTGAAATAGTATTTTAAAAAAACACTCAATAAAAATAATT
AATAAAAGACAAACAAACACAAAATAAGAGTCAGCTAAGAAGACTGAACAACTTGAAGCT
ACTAGGATTTATAAAGGTTAAGGAATGCGGAGGTGCAGATCTTAAAAATGAATAAGAATA
ATAGCTACAATTTAAAAAAACATTCAAAGTGAATTAAAAAGGATTAATTTTTGATAATCA
TTAATACTTTCTTAACCTTAATGCGGTGATAAGCAACAATCACTTGATAAGTAATTATTC
TATTTATTCATTTTATTAAATATTTTTCACTCAATAGGAATAATAATTAAGCATGATTTA
TTCTTAGTATGCAAATTAAATAAAAAAATATTTAATTTCTTTTAAATTAGTTAGAAACTA
CCTTATTTTTTTAATTTATCAATCAATCAATCACTCATTTATCTATTCACTATTCACACT
ATTTACTGATTCAGTCATTAAAAAAATATTTGATTTTCATATATAAATATCTATTTACAG
CCTTTACTCTTTTTAATTTATTGTAATCAATCAATTTGACTGACTGAATGAGTCATCAAA
ATAAATTCATTAATATTTTGCTAGTTTAGCATATTTCTTTTTAATCGTCAATATAAACTG
GATCAAGCTTTACTTCTGAATCGACATATTAAGCAAATCTTAATAACTAAAATAATTTTT
CCATATCAAATAATGAGAGGTCCGAAAAAATTATGAAGATATTTCAATTTTTATTATGAG
CAAATATCATTTCGGGATTGGATTAATAAATATTTTTTAATATTCTTAAGAAGTTACAAC
GCAGAAGCAGCTCTAATTAATTCACATATTTTATTTATTCTTTTCAGTTAATACGTTGCT
AATTTCAGTAGTTGAAATAATGATATAATAATGATATAGATTTACAAACGGAAGTATATA
TTTATTTATTTTATATTTCAACTAAGTCATTTGCGATTATTTTGTTGAAAAAAGAACTTT
TCTAAATAAAGATTGAATTTATTTTGTATTTAGTTAAGCAAAGATAAAATCAATATGAAT
TTTCCTCTGCAATTAAATATACAAAGAGAATATTATTATTAAATAGAAATTTGAATGAGT
GGTTGATTGATTGAATGTAAATAAAATGAGGATTTGCAAAAGAAAAGATTGCATTAATAG
ATTAATTTTTAATATGATTAGAGAATAAAATTGAATTATTTTTATAAATTTAAATTATAC
ATTTATAATTTTAATTTTATTCAATTTTAGGATAATCTAGTCCAGTAGAAAGGTTAAAGG
CTAATCTTTACGATGAAGAGAGAGTTCCTTAAATTAGCTAATATATTAAGACTAATAGTA
CCAATTTTTAAGATACTCCTCTGAGTTAAACTAATTAATATAATCTTATTTCCTGCTCAA
ATGGTAGTAACAATAACAAAAAGAAAGCAGCTTTTCGTCGTCGTAGCTGCTATTGCAACT
AAACTGGTAAGTAAAGCCAAAAAGCTTAAAAAATAGACTTCTAATTGCCTACAACCTTCA
TTAAAAATAGAATTTACTAGCGTATGAAAAGAAAGTAGGAAATGAAAATGAATTTGAATG
AAAAAGATTTGATTATTTAGAATTTAAATCGTACATTCGACATTCAAGAAAAGAATTCTG
CTCGCGGAAGTCTGCTAAATAGTCCTAATATCATGAATATGCAGCAAACATTTAACTTTT
TAGACACTCCTATGTCAGGAAGAGTTATGAATACACCTAGCGCAAGCAATAGGTATAACA
ATTAACACCACGTCCATTCAAGCTAAGCTTAAAGAAGCTAATTTTCTTACATGACATCAC
CAAAGAATGGCTAACAACATTCTAATTAAGGAACTGCCACTCATAGTAAGAAAGATGATA
ACACATTAAAAAATGCTCAAAGTCCTGTAAATCGTAATCCTAACAGCAAGCCTACATTCG
CAGAAACTATTGAATATATCAAAGAAGAACAGAGTCAACAGTAAAATGTTACTCCTTAAT
CTAAATAAGAAAAAAAATCACCTCAAAAAACAAACTCATAAATCTCTAGCAAAGAGTTGG
AGTTATCTTTAAATAAAGTAGTTCATCGTAAAAATATTTCTAGCAATAAAAATTCCCCTA
AAAATAATCATGTTTCTGCTTCTCCTAATCGCTAAACTCCTGTAAGCAGCAGCAAGAAGA
GTAGCATGTTCAACTACTTTGGCGTAGGAGGAAAAACCTTAAAGGACGACTCACACTAAA
AATAATAATATGAAAGCATTTATCCAGAACAAGTGGAGAAAAGAAAAAAATGGATCACAA
AGCTTCGTATTGCTACCAAATTAGTTGGTTTTTAAGAAAAACAAAGAAAAAAATCTATGT
TGTACTAGTAAGATTATTACAAGGCACTTGAAGAAGTTGCAAATAACGAGGTTGAGCTTG
AAAATTTAGAATAAAATGATGAATTTAATCACAATAATTAGGAGAAAAAAAACATTTTAA
TTAGAAAAGTCAAATAAAGCAATATCAATAAAAATAATTTTATGCTAAATTAAATAGTAA
AGCAACACAACTTAAAATTCAATTCCACAATAGGCTCTTTTCTTGATATGCGCACTAAAA
GTCAAAATTGTCTTCTTCCTTCAACGAATTCTTCCATCTTTGCCTTCCCTTAGAAATTGA
GTAGAAGACATTTAGTAAGCCCATTCAATTACGACAGCAAATCGGAATATATTATCCATA
AAAAGGATAGTAAAATAGGTGCTTATCTGTAGCCCTTCCCAGTAATTCTTTCGCCATCTC
CAAGCAAATAAGATCATAGTAAAAAATCTCAGAGCAAAACAAACTAGCTTTTCTAATCAT
CTTTTGTTACAAATACTGATAAAAAAAATAAAAAATCGAATGAGATAATCAATAGAAGTA
GTTCTCATAAAAAAATTAACTCATCAACAATGACAGAACTTGGTAAAGGAAATTAAAATA
AAAATCATTTTAGTAAGAATTATTTGCTCATGCCAAAAAGTGCGAAATCTGGTTAAATTT
AATTAAGTAATTCATCAAATAGCATAGAAGAATTGAATGCTACTGAAAATAATCTCTAGA
ATGAAGCAAGTAAATCTAGTCTAGGATTAAAATCTAATAACGATAAAGACAGCCACTAAA
ATAGCCAGCAAAATATAGTAAGTCTTGAATAGCTCGGAAGATATGAAACATATTTTGCAA
AAAAGCCAGATTAAAAAAATTAAAAAGTTAACAATTAATCAAAAACTTAGCAAAAATTCT
AGCTGCTCATAAACAATTAGTCGATACAAAACTCTTATTTAATAAAAAGCAATTTAAAAA
ATTCAAATTCTATAAATCACTTAAGTAAAACCATAAATTTTGGTTAAATTAATCAAAAAA
CAGCTTCATAGCCTGATTTACTTCAAAGTACTTTCAAGCACGACACATCAAATGTATCAT
CTAACAATTTGACCATAAAAAGTCCAAATATTTAAAACAGAAGACCCAGCTATCTTTAGC
AAAAATTTGAAAGTAAGACCCATCGTAAATCAATCCTACAGAGCTATTTGGTTTGA

>TTHERM_00011740(protein)
MINKRTSFTSKMLSGRKNSCQSTTSSAESHNFRSTNDIDHKVHLIEKSPNKYKLITENKQ
TQNKSQLRRLNNLKLLGFIKVKECGGADLKNEQEQQLQFKKTFKVNQKGLIFDNHQYFLN
LNAVISNNHLIRQSSPVERLKANLYDEERVPQISQYIKTNSTNFQDTPLSQTNQYNLISC
SNGSNNNKKKAAFRRRSCYCNQTGKQSQKAQKIDFQLPTTFIKNRIYQRMKRKQEMKMNL
NEKDLIIQNLNRTFDIQEKNSARGSLLNSPNIMNMQQTFNFLDTPMSGRVMNTPSASNRY
NNQHHVHSSQAQRSQFSYMTSPKNGQQHSNQGTATHSKKDDNTLKNAQSPVNRNPNSKPT
FAETIEYIKEEQSQQQNVTPQSKQEKKSPQKTNSQISSKELELSLNKVVHRKNISSNKNS
PKNNHVSASPNRQTPVSSSKKSSMFNYFGVGGKTLKDDSHQKQQYESIYPEQVEKRKKWI
TKLRIATKLVGFQEKQRKKSMLYQQDYYKALEEVANNEVELENLEQNDEFNHNNQEKKNI
LIRKVKQSNINKNNFMLNQIVKQHNLKFNSTIGSFLDMRTKSQNCLLPSTNSSIFAFPQK
LSRRHLVSPFNYDSKSEYIIHKKDSKIGAYLQPFPVILSPSPSKQDHSKKSQSKTNQLFQ
SSFVTNTDKKNKKSNEIINRSSSHKKINSSTMTELGKGNQNKNHFSKNYLLMPKSAKSGQ
IQLSNSSNSIEELNATENNLQNEASKSSLGLKSNNDKDSHQNSQQNIVSLEQLGRYETYF
AKKPDQKNQKVNNQSKTQQKFQLLINNQSIQNSYLIKSNLKNSNSINHLSKTINFGQINQ
KTASQPDLLQSTFKHDTSNVSSNNLTIKSPNIQNRRPSYLQQKFESKTHRKSILQSYLV