Identifiers and Description

Gene Model Identifier

TTHERM_00118600

Standard Name

PYK1 (PYruvate Kinase)

Aliases

PreTt27179 | 8.m00439 | 3812.m02471

Description

PYK1 pyruvate kinase complex alpha subunit; pyruvate kinase; converts phosphoenolpyruvate to pyruvate during glycolysis

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• magnesium ion binding (IEA) | GO:0000287
• potassium ion binding (IEA) | GO:0030955
• pyruvate kinase activity (IEA) | GO:0004743

Biological Process

• glycolytic process (IEA) | GO:0006096

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_6611	0
	Description: None
Tetrahymena borealis	EI9_03875.1	9.997093137033517e-262
	Description: pyruvate kinase (475 aa)
Oxytricha	Contig18083.0.g114	9.997093137033517e-262
	Description: Pyruvate kinase, barrel domain
DictyBase	DDB_G0283247	4.998226778107862e-142
	Description: pyk on chromosome: 4 position 344914 to 346711
WormBase	WBGene00014001	8.997006431083756e-128
	Description: locus:pyk-2 Pyruvate kinase status:Confirmed UniProt:Q23539 protein_id:CAA93424.2
SGD	YAL038W	1.9994050701445255e-104
	Description: CDC19 Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00118600(coding)
ATGGACTCAAGCTACTCTGAATTCACTCTTGATGGTATTCTCTCCCACACTGACTACTCC
AAGAGAAAGACCAAAATTGTCTGCACTATTGGACCCTCTTGTTGGGATCACGATAATCTC
GTTTAATTGCTTGAAAATGGTATGAATGTTGCTCGTTTGAACTTCTCCCATGGTGATCAC
GCTGGTCATGGAGAAACTGTTAGAAGACTTAAGGAAGCCTTCAAAGCCAGAAAGAACATT
CAATGTGCTCTTATGCTTGATACTAAAGGACCAGAAATCAGAACTGGTTTGGTAAAAGAC
TAAACTAAGAAGCTCATCAACCTCGTTGCTGGATAAGAATTAGAAATAACTACTGACTAT
AGCGTTTTAGGAGATGAGAAAGTTCTTGCTTGCTCTTACAAAAGTTTACCCAAGAGTGTC
AAAGTTGGTGGTTAAGTCTTGATAGCCGATGGTACTTTGGTTTGCATAGTTAAGGAAATC
AAATAGGACAGTATCATCGTAAATGTTTAAAATACCTGCAGTATTGGTGAAAAGAAGAAT
ATGAATTTACCAGGTGCTATTGTTGATCTCCCTACAGTCACTGAAAAAGACGAAGATGAT
ATTGTTAACTTCGGTCTTAAGCATGGTATTGATTGTATTGCCTTGTCCTTCGCCAGAAAA
GCTGAAGATATTGAATACGTTAGAGATATCTTGGGACCTCAAGGTGAACACATTAAGATC
ATTGCAAAGATTGAAAACCAAGAAGGTCTTCATAATTATGAATAAATTTTAGATGCTGCC
GATGGTATCATGGTTGCTCGTGGTGATTTAGGTATGGAAATCCCTCCTTAGAAGGTCTTC
GTAGCTCAAAAATGGATGATCCGCAAAGCCCTTGAAAAAGGTAAACCCATTATTACTGCT
ACCTAAATGATGGAAAGTATGATTAAAAATCCCAGACCTACTAGAGCTGAAGCCAGTGAT
GTTGCTAATGCAGTTTTGGATGGTACTGATGCAGTTATGCTTTCAGGTGAAACCGCTAAC
GGATCTTTCCCTATTCAAGCTGTCTAAACCATGGCTTACATTTGCTCAGAGGCCGAACTT
TGCTATGACAACAGACAAACTTTCTGGTAAAGAACAAACAACAAGAAAAAAGTTTCTGCT
GTTGAATCTATGGCTATCTCTGCTGTCTAAATGAGTTTTGAAATTGAAAGTCCTGTTATC
ATCGTATTTACTACTAATGGTGATATGGCTAGATATGTCTCCAAGTACAGACCAAGTGCT
TAAATTTTCGTTGTATCAACTGAAAACGGTACAATTAAAGGCCTTTGCACTACTTTTGGT
GTCAGATGCTTAAGAGTCCCTTCATTCTAAGGTATTAATAAGCTCATTGATTATGCTGTT
GATGCTGCTAAAGAGTAAGGATTTATCAAGTCAGGATAAAATGCAATTGTAATCCTTGGC
TCAAACGAAGAAGAACCTGATCAAGGTGACATCCTTAAAATCAAGGAAGTTAAATGA

>TTHERM_00118600(gene)
ATGGACTCAAGCTACTCTGAATTCACTCTTGATGGTATTCTCTCCCACACTGACTACTCC
AAGAGAAAGACCAAAATTGTCTGCACTATTGGGTAACCAGCAAATCAATTTTATATTATT
CATATATCTTTTGACATCCTTTCATGATTGTGTTTGCTAACAATTTGTTTTAATAATATA
GACCCTCTTGTTGGGATCACGATAATCTCGTTTAATTGCTTGAAAATGGTATGAATGTTG
CTCGTTTGAACTTCTCCCATGGTGATCACGCTGTAAGCTTCTAAAATATATTATTATTTT
GCAAAAAAGCACAATTTCAAGCTTATTAAATGACATTTTTGCTTACTATCTCCCATATTT
TAATCATAATAGGGTCATGGAGAAACTGTTAGAAGACTTAAGGAAGCCTTCAAAGCCAGA
AAGAACATTCAATGTGCTCTTATGCTTGATACTAAAGTACGTCATATTTTATACTTCACA
GCCCTTTAATAGCCCTAAAATTAATATTTTCAAAAGATTTCAATCAATTTTTTTCTAAAT
TATACTATTTATAATCTAAAAGGGACCAGAAATCAGAACTGGTTTGGTAAAAGACTAAAC
TAAGAAGCTCATCAACCTCGTTGCTGGATAAGAATTAGAAATAAGTAAAGCTTAGTATTA
AGTATTAATGAAATAAATATCATTTTTCTTTTTTAATTGTAATTTTCTAGCTACTGACTA
TAGCGTTTTAGGAGATGAGAAAGTTCTTGCTTGCTCTTACAAAAGTTTACCCAAGAGTGT
CAAAGTTGGTGGTTAAGTCTTGATAGCCGATGGTACTTTGGTTTGCATAGTTAAGGAAAT
CAAATAGGTAAAATATTAATTAGTCTTATTTAAAAAAACGTTTTTTATTTGCGAAACAAA
CAACAACAATAATAAAAATAAATAAGCATAAAGAAACTGATAGAACTTTTTAATGAAAAT
AAATAAAGAGTTTGTTTTTTATCTATAATCAGAGATAGTTAATTAATTTAAAATAAAAGC
CAAATCAATAAAAATACAATTTATTTATTGTTGGTTATTAAATTTTGATTCTGATCACAA
AAAAATTAATTATAAAAATATTTACAAAGCAAGATATTAAACTTAATTTATTGAGAATAA
TCAATCCCACTTAATAATTATTAATGCTTTAATGAATGAATGCAATTAATTTCTTCTTTT
TAACAATACAATAGGACAGTATCATCGTAAATGTTTAAAATACCTGCAGTATTGGTGAAA
AGAAGAATATGAATTTACCAGGTGCTATTGTTGATCTCCCTACAGTCACTGAAAAAGACG
AAGATGATATTGTTAACTTCGGTCTTAAGCATGGTATTGATTGTATTGCCTTGTCCTTCG
CCAGAAAAGCTGAAGATATTGAATACGTTAGAGATATCTTGGGACCTCAAGGTGAACACA
TTAAGATCATTGCAAAGATTGAAAACCAAGAAGGTCTTCATAATTATGAATAAATTTTAG
ATGCTGCCGATGGTATCATGGTTGCTCGTGGTGATTTAGGTATGGAAATCCCTCCTTAGA
AGGTCTTCGTAGCTCAAAAATGGATGATCCGCAAAGCCCTTGAAGTAATTTTAATACTAC
CTATCTATTTACTAATTTATTTTCTAATAAACAGAAAGGTAAACCCATTATTACTGCTAC
CTAAATGATGGAAAGTATGATTAAAAATCCCAGACCTACTAGAGCTGAAGCCAGTGATGT
TGCTAATGCAGTTTTGGATGGTACTGATGCAGTTATGCTTTCAGGTGAAACCGCTAACGG
ATCTTTCCCTATTCAAGCTGTCTAAACCATGGCTTACATTTGCTCAGAGGCCGAACTTTG
CTATGACAACAGACAAACTTTCTGGTAAAGAACAAACAACAAGGTATTTATTTTTATTTT
ATAGAATTAAAAATAAAATTTAGATAAGATTAACATACAAAAAGGATTTTTATCAAAATA
AAGAAAGATACAATTTGCAAATTTATTTTAGTTAGATATTATTAAACAAACTTGAATTAT
TTGTTTAGCATAAATAACATAAACATTATTTACAAAGCTAACACAAAATATTTATGATAT
ATAAAGATTCTTAAAATTAATATTTTTATGTTAAATTAATATTAAAAATAGAAAAAAGTT
TCTGCTGTTGAATCTATGGCTATCTCTGCTGTCTAAATGAGTTTTGAAATTGAAAGTCCT
GTTATCATCGTATTTACTACTAATGGTGATATGGCTAGATATGTCTCCAAGTACAGACCA
AGTGCTTAAATTTTCGTTGTATCAACTGAAAACGGTACAATTAAAGGCCTTTGCACTACT
TTTGGTGTCAGATGCTTAAGAGTCCCTTCATTCTAAGGTGAAAATTACTATTTTAACTGT
AAAATAAATATTAACTATATTCATATTAATAGGTATTAATAAGCTCATTGATTATGCTGT
TGATGCTGCTAAAGAGTAAGGATTTATCAAGTCAGGATAAAATGCAATTGTAATCCTTGG
CTCAAACGAAGAAGAACCTGATCAAGGTGACATCCTTAAAATCAAGGAAGTTAAATGA

>TTHERM_00118600(protein)
MDSSYSEFTLDGILSHTDYSKRKTKIVCTIGPSCWDHDNLVQLLENGMNVARLNFSHGDH
AGHGETVRRLKEAFKARKNIQCALMLDTKGPEIRTGLVKDQTKKLINLVAGQELEITTDY
SVLGDEKVLACSYKSLPKSVKVGGQVLIADGTLVCIVKEIKQDSIIVNVQNTCSIGEKKN
MNLPGAIVDLPTVTEKDEDDIVNFGLKHGIDCIALSFARKAEDIEYVRDILGPQGEHIKI
IAKIENQEGLHNYEQILDAADGIMVARGDLGMEIPPQKVFVAQKWMIRKALEKGKPIITA
TQMMESMIKNPRPTRAEASDVANAVLDGTDAVMLSGETANGSFPIQAVQTMAYICSEAEL
CYDNRQTFWQRTNNKKKVSAVESMAISAVQMSFEIESPVIIVFTTNGDMARYVSKYRPSA
QIFVVSTENGTIKGLCTTFGVRCLRVPSFQGINKLIDYAVDAAKEQGFIKSGQNAIVILG
SNEEEPDQGDILKIKEVK