Identifiers and Description

Gene Model Identifier

TTHERM_00158520

Standard Name

HSP82 (Heat Shock Protein 82 )

Aliases

PreTt28442 | 13.m00537 | 3829.m01257

Description

HSP82 predicted protein; Hsp90 family member; 82 kDa heat shock-inducible protein; found in heat shock induced cytosolic hetero-oligomeric complexes with tubulin and hsp73; localizes to mature basal bodies and cortical cytoskeleton; involved in cortical patterning

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• axonemal microtubule (IDA) | GO:0005879
• cell cortex (IDA) | GO:0005938
• cilium (IDA) | GO:0005929
• cytoplasm (IDA) | GO:0005737
• microtubule (IDA) | GO:0005874
• microtubule basal body (IDA) | GO:0005932

Biological Process

• cortical cytoskeleton organization (IMP) | GO:0030865
• protein folding (ISS) | GO:0006457
• response to heat (IDA) | GO:0009408

Domains

• ( PF00183 ) Hsp90 protein
• ( PF02518 ) ATPase, histidine kinase-, DNA gyrase
• ( PF06908 ) Protein of unknown function (DUF1273)

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_14295	0
	Description: None
WormBase	WBGene00000915	9.997093137033517e-262
	Description: locus:daf-21 Heat shock protein 90 status:Confirmed UniProt:Q18688 protein_id:CAA99793.1
Tetrahymena borealis	EI9_05309.1	9.997093137033517e-262
	Description: hsp90-like protein (705 aa)
DictyBase	DDB_G0267400	9.997093137033517e-262
	Description: hspD on chromosome: 1 position 1280990 to 1283391
Oxytricha	Contig17274.0.g46	9.997093137033517e-262
	Description: Hsp90 protein
SGD	YPL240C	9.997093137033517e-262
	Description: HSP82 Hsp90 chaperone required for pheromone signaling and negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding and nucleotide addition; interacts with Cns1p, Cpr6p, Cpr7p, Sti1p

General Information

No Data fetched for General Information

Associated Literature

1. Ref:25588944: Woehrer SL, Aronica L, Suhren JH, Busch CJ, Noto T, Mochizuki K (2015) A Tetrahymena Hsp90 co-chaperone promotes siRNA loading by ATP-dependent and ATP-independent mechanisms. The EMBO journal 34(4):559-77
2. Ref:15154550: Ketola T, Laakso J, Kaitala V, Airaksinen S (2004) Evolution of Hsp90 expression in Tetrahymena thermophila (Protozoa, Ciliata) populations exposed to thermally variable environments. Evolution; international journal of organic evolution 58(4):741-8
3. Ref:12095102: Frankel J, Williams NE, Nelsen EM, Keeling PJ (2002) An evaluation of Hsp90 as a mediator of cortical patterning in Tetrahymena. The Journal of eukaryotic microbiology 48(2):147-60
4. Ref:9247200: Williams NE, Nelsen EM (1997) HSP70 and HSP90 homologs are associated with tubulin in hetero-oligomeric complexes, cilia and the cortex of Tetrahymena. Journal of cell science 110 ( Pt 14)( ):1665-72

Sequences

>TTHERM_00158520(coding)
ATGTCTCAACAAGCTGAACACTTTGCTTTCGAAGCCGATATCCAACAATTGATGGGTTTG
ATCATCAACACTTTCTACTCCAACAAGGAAATTTTCTTGAGAGAATTGATTTCCAATGCC
TCCGATGCTTTGGATAAGATTAGATACATTTCCATCACCGACAGCGAAAAAGCCAAGTTA
GAAGTTGAACCTAACTTCAGAATTAGAATCATTCCCGATAAGGCCAACAATACCCTTACC
CTCTGGGATACCGGTATTGGTATGACCAAGAAGGAATTGATCAACAACTTGGGTACTATC
GCTAAGTCTGGTACCAAGGCCTTCATGGAAGCCCTCTCCAGTGGTGCTGATATTTCTATG
ATTGGTCAATTCGGTGTCGGTTTTTACTCTGCTTACTTGGTTGCCGAAAAGGTCGAAGTT
ATCTCCAAGTCCAACGATGATGAATCCCAATGGAGATGGGAATCCTCTGCTGGTGGTACT
TTCACCGTCGTCAACGATGATGAAAACCCTGAAAAGCTCACCAGAGGTACCAAGATCATC
CTCCACATGAAGAACGATAACTTAGAATTCTTAGAAGAAAGAAGAATCAAGGACTTGATC
AAGAAGCACTCTGAATTCATTGCTTTCCCCATCGAATTATAAGTTGAAAAGACCGAAGAA
AAGGAAGAAACCGACGAAGAAGATGAAGAAAAGGAAAAGGAAGATAAGGAAAAGACCGAT
GAACCCGAAATTAAGGAAGAAACCGAAAAGAAGGACAAGAAGAAAAAGAAAGTTAAAGTT
GTCCACACTGAATTCGAAGAATAAAACAAGAACAAGCCTCTTTGGATGAGAAAGCCCGAA
GAAATCACCAAGGAAGAATACGTTAACTTCTACAAGTCCCTCACCAACGATTGGGAAGAA
CACTAAGCTGTCAAGCAATTCTCCGTTGAAGGTCAACTCGAATTCAGAGCTATCCTCTTC
ATCCCCAAGAGAGCTCCCTTCGACTTATTCGAAACCAAGAAGAAGAAAAACAACATCAAG
CTCTACGTCAGAAGAGTCTTCATTATGGATGACTGCGAAGAACTCATCCCCGAATATCTT
AACTTCATTAAGGGTGTTGTTGATTCTGAAGATCTCCCTCTTAACATCTCCAGAGAATTC
CTCCAACACAACAAGATCCTCAAGGTCATCAAGAAGAACATCGTCAAGAAGTGCCTCGAC
CTTATCCAAGAAGTTGCTGATAACGAAGAAGACTTCAAGAAGTTCTACGAACAATTCGGT
AAGAACCTCAAGCTCGGTATCCACGAAGACTCTGCCAACAGAGAAAAGCTCTCTTCCTTC
CTCAGATATCACTCCTCCAAGTCTGGTGAAGAATTAACCACCCTCAAGGACTACGTCTCC
AGAATGAAAGAAGGTCAAAAGGACATTTTCTTCATTACTGGTGAATCCAGAGCTGCTGTT
GCTGCTTCTCCCTTCGTTGAAAGCCTTAGAAAGAGAGGTTATGAAGTCCTTTACATGGTT
GACCCCATCGATGAATACGTCATCCAACAATTAAAGGAATACGACGGTAAGAAACTCAAG
AACTGCTCCAAGGAAGGTCTTGAACTCGAATAAACTGAAGATGAAAAGAAGAAGTTCGAA
GAAAAGAAGGCTGCCTACGAACCTCTTTGCAAGCAAATCAAGGAAGTCCTCGGTGACAAG
GTCGAAAAGGTCGTCGTTGGTCAAAGACTCGACGAATCTCCTTGCGTCCTCGTTACTGGT
GAATACGGCTGGTCCGCCAATATGGAAAGAATCATGAAGGCTCAAGCTCTCAGAGATGCT
TCCATGTCCACATATATGATCTCCAAGAAGACCATGGAAATCAATCCCGATAACGCCATC
GTCTAAGAACTCAAGACCAGATCCGACAAGGACAAGGCTGACAAGACCGTCAAGGATCTC
ATCTGGTTACTCTTCGAAACCTCCCTCCTCACTTCTGGTTTCTCCCTCGATGACCCCTCT
TCTTTCGCTAACAGAATCCACAGAATGATTAAGCTTGGTCTCCAATTGGACGACTCTCAC
ATTGATGAAGAAGTTCCCGGACTTAGCCAAGAAGCTGAAAAGACTGAAAACACCAACAAC
GCTATGGAAGATGTTGATTGA

>TTHERM_00158520(gene)
ATGTCTCAACAAGCTGAACACTTTGCTTTCGAAGCCGATATCCAACAATTGATGGGTTTG
ATCATCAACACTTTCTACTCCAACAAGGAAATTTTCTTGAGAGAATTGATTTCCAATGCC
TCCGATGCTTTGGATAAGATTAGATACATTTCCATCACCGACAGCGAAAAAGCCAAGTTA
GAAGTTGAACCTAACTTCAGAATTAGAATCATTCCCGATAAGGCCAACAATACCCTTACC
CTCTGGGATACCGGTATTGGTATGACCAAGAAGGAATTGATCAACAACTTGGGTACTATC
GCTAAGTCTGGTACCAAGGCCTTCATGGAAGCCCTCTCCAGTGGTGCTGATATTTCTATG
ATTGGTCAATTCGGTGTCGGTTTTTACTCTGCTTACTTGGTTGCCGAAAAGGTCGAAGTT
ATCTCCAAGTCCAACGATGATGAATCCCAATGGAGATGGGAATCCTCTGCTGGTGGTACT
TTCACCGTCGTCAACGATGATGAAAACCCTGAAAAGCTCACCAGAGGTACCAAGATCATC
CTCCACATGAAGAACGATAACTTAGAATTCTTAGAAGAAAGAAGAATCAAGGACTTGATC
AAGAAGCACTCTGAATTCATTGCTTTCCCCATCGAATTATAAGTTGAAAAGACCGAAGAA
AAGGAAGAAACCGACGAAGAAGATGAAGAAAAGGAAAAGGAAGATAAGGAAAAGACCGAT
GAACCCGAAATTAAGGAAGAAACCGAAAAGAAGGACAAGAAGAAAAAGAAAGTTAAAGTT
GTCCACACTGAATTCGAAGAATAAAACAAGAACAAGCCTCTTTGGATGAGAAAGCCCGAA
GAAATCACCAAGGAAGAATACGTTAACTTCTACAAGTCCCTCACCAACGATTGGGAAGAA
CACTAAGCTGTCAAGCAATTCTCCGTTGAAGGTCAACTCGAATTCAGAGCTATCCTCTTC
ATCCCCAAGAGAGCTCCCTTCGACTTATTCGAAACCAAGAAGAAGAAAAACAACATCAAG
CTCTACGTCAGAAGAGTCTTCATTATGGATGACTGCGAAGAACTCATCCCCGAATATCTT
AACTTCATTAAGGGTGTTGTTGATTCTGAAGATCTCCCTCTTAACATCTCCAGAGAATTC
CTCCAACACAACAAGATCCTCAAGGTCATCAAGAAGAACATCGTCAAGAAGTGCCTCGAC
CTTATCCAAGAAGTTGCTGATAACGAAGAAGACTTCAAGAAGTTCTACGAACAATTCGGT
AAGAACCTCAAGCTCGGTATCCACGAAGACTCTGCCAACAGAGAAAAGCTCTCTTCCTTC
CTCAGATATCACTCCTCCAAGTCTGGTGAAGAATTAACCACCCTCAAGGACTACGTCTCC
AGAATGAAAGAAGGTCAAAAGGACATTTTCTTCATTACTGGTGAATCCAGAGCTGCTGTT
GCTGCTTCTCCCTTCGTTGAAAGCCTTAGAAAGAGAGGTTATGAAGTCCTTTACATGGTT
GACCCCATCGATGAATACGTCATCCAACAATTAAAGGAATACGACGGTAAGAAACTCAAG
AACTGCTCCAAGGAAGGTCTTGAACTCGAATAAACTGAAGATGAAAAGAAGAAGTTCGAA
GAAAAGAAGGCTGCCTACGAACCTCTTTGCAAGCAAATCAAGGAAGTCCTCGGTGACAAG
GTCGAAAAGGTCGTCGTTGGTCAAAGACTCGACGAATCTCCTTGCGTCCTCGTTACTGGT
GAATACGGCTGGTCCGCCAATATGGAAAGAATCATGAAGGCTCAAGCTCTCAGAGATGCT
TCCATGTCCACATATATGATCTCCAAGAAGACCATGGAAATCAATCCCGATAACGCCATC
GTCTAAGAACTCAAGACCAGATCCGACAAGGACAAGGCTGACAAGACCGTCAAGGATCTC
ATCTGGTTACTCTTCGAAACCTCCCTCCTCACTTCTGGTTTCTCCCTCGATGACCCCTCT
TCTTTCGCTAACAGAATCCACAGAATGATTAAGCTTGGTCTCCAATTGGACGACTCTCAC
ATTGATGAAGAAGTTCCCGGACTTAGCGTAAGCTTTTTGAATTTTTTAAATATTTCTCAA
ATTTCTCAATTAATTAATTTGTAATATTCTAATTCTAAATCCTATTTTTTATTAAATAAT
AGCAAGAAGCTGAAAAGACTGAAAACACCAACAACGCTATGGAAGATGTTGATTGA

>TTHERM_00158520(protein)
MSQQAEHFAFEADIQQLMGLIINTFYSNKEIFLRELISNASDALDKIRYISITDSEKAKL
EVEPNFRIRIIPDKANNTLTLWDTGIGMTKKELINNLGTIAKSGTKAFMEALSSGADISM
IGQFGVGFYSAYLVAEKVEVISKSNDDESQWRWESSAGGTFTVVNDDENPEKLTRGTKII
LHMKNDNLEFLEERRIKDLIKKHSEFIAFPIELQVEKTEEKEETDEEDEEKEKEDKEKTD
EPEIKEETEKKDKKKKKVKVVHTEFEEQNKNKPLWMRKPEEITKEEYVNFYKSLTNDWEE
HQAVKQFSVEGQLEFRAILFIPKRAPFDLFETKKKKNNIKLYVRRVFIMDDCEELIPEYL
NFIKGVVDSEDLPLNISREFLQHNKILKVIKKNIVKKCLDLIQEVADNEEDFKKFYEQFG
KNLKLGIHEDSANREKLSSFLRYHSSKSGEELTTLKDYVSRMKEGQKDIFFITGESRAAV
AASPFVESLRKRGYEVLYMVDPIDEYVIQQLKEYDGKKLKNCSKEGLELEQTEDEKKKFE
EKKAAYEPLCKQIKEVLGDKVEKVVVGQRLDESPCVLVTGEYGWSANMERIMKAQALRDA
SMSTYMISKKTMEINPDNAIVQELKTRSDKDKADKTVKDLIWLLFETSLLTSGFSLDDPS
SFANRIHRMIKLGLQLDDSHIDEEVPGLSQEAEKTENTNNAMEDVD