Identifiers and Description

Gene Model Identifier

TTHERM_00193660

Standard Name

VMA4 (Vacuolar Membrane Atpase)

Aliases

PreTt06649 | 16.m00305

Description

VMA4 vacuolar ATP synthase subunit E; vacuolar ATP synthase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• proton-transporting two-sector ATPase complex, catalytic domain (IEA) | GO:0033178

Molecular Function

• proton-transporting ATPase activity, rotational mechanism (IEA) | GO:0046961

Biological Process

• proton motive force-driven ATP synthesis (IEA) | GO:0015986

Domains

• ( PF01991 ) ATP synthase (E/31 kDa) subunit

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_03646.1	6.001368665888701e-135
	Description: vacuolar ATP synthase (230 aa)
Oxytricha	Contig16360.0.g4	2.999884853455273e-42
	Description: ATP synthase (E/31 kDa) subunit
WormBase	WBGene00006917	6.001249495680822e-29
	Description: locus:vha-8 status:Confirmed UniProt:Q95X44 protein_id:CCD65002.1
SGD	YOR332W	1.9993007828132465e-27
	Description: VMA4 Subunit E of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane
DictyBase	DDB_G0275701	3.001290106883431e-24
	Description: vatE on chromosome: 2 position 5679309 to 5680331
Stentor Coeruleus	SteCoe_21951	0.0000000000006914400106940203
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:28087716: Cheng CY, Young JM, Lin CG, Chao JL, Malik HS, Yao MC (2016) The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila. Genes & development 30(24):2724-2736

Sequences

>TTHERM_00193660(coding)
ATGGCAGATTTTATTAATAAACCTCAAGAAAACGTTTAGAAGATCGTTGAAGCCATCAAA
TCTGAAGCAGAAGAGAAGGCTGAACAAATTAAAAAGAATGCTGAAGAATAATTTAAGATT
CAAAAAAATAATATTGTCAATACTGAAAAGGATAAAATCATTGAAGAATATAAAAAGAGA
TTAGAAAAGCTCATAGTTGACAGAAGAATTCAACGTTCTGCCAAAATCAATGAATAGAGA
TTAGAAAAAATGAAAGCTCGTTTTGACTTTATTGAAAAGCTAAAGGGTGAAATTTCTAAT
AAAATCGTTTAATCCGTTTCAGACCCTAATAAATATAAAAATGTCTTCAAGCAACTTATA
ATCTAGGCCTTGATCAAGTTGATGGAACCTAAGGTTGAGTTAAAAGTAATGAAGAAAGAT
TTGTAGCTTGCTCGTGAAGTAAAGACAGAATGTGAAAATGAATTCAAGGCAATTGCTAAG
AGAGAATGTAATAGAGACTTTAACTGTACTATTATTATAAATGAATACCACTCTCTTGAA
GAAGAAAATCCTAAAGTTATTGGAGGTATTGTTCTCACTTGCGATGGTGGTAGAATTTAG
GTAAACAACACTTTAAATGCAAGAGTTGATCTTGCTTTCTAAGAATTCCTTCCTGACATC
AGAAGAATTCTTTTCCCTTCTATGAAATGA

>TTHERM_00193660(gene)
ATGGCAGATTTTATTAATAAACCTCAAGAAAACGTTTAGAAGATCGTTGAAGCCATCAAA
TCTGAAGCAGAAGAGAAGGCTGAACAAATTAAAAAGAATGCTGAAGAATAATTTAAGATT
CAAAAAAATAATATTGTCAATACTGAAAAGGATAAAATCATTGAAGAATATAAAAAGAGA
TTAGAAAAGCTCATAGTTGACAGAAGAATGTAATAATTTTATTGAAAAAGAATTGAAAAT
AATTATATTTTTAAGCAGTAAATTTAACAATTAAGCACATTTATTACTAAAAAAATCTAA
AATTATTTTCAAATATCTTAAAATAGTCAACGTTCTGCCAAAATCAATGAATAGAGATTA
GAAAAAATGAAAGCTCGTTTTGACTTTATTGAAAAGCTAAAGGGTGAAATTTCTAATAAA
ATCGTTTAATCCGTTTCAGACCCTAATAAATATAAAAATGTCTTCAAGCAACTTATAATC
TAGGTAATCCATTCAGCTAATATCCTTCATGTTTTAACTAAAAAATATAATTGCATTTGA
AATAAAATAATCAAATGATAAATATAGCAGCAGATAAAATAGTAATCCTATAATTTAGAT
TAGCATTAACAAAGACCAATAAGGTTGTTCAAAAAATATTAAAATGTTAGCATTGAAATT
TAGGTTAAAAATTTAGCATAATTGAATAAAAAATAAAATGATTCTATGGCAAATATTATA
TATCGAAATAAATATCAAACTTTGCTAAACACAAGATATATTAATTACTGCTTTTAATTA
AGTTATTAGCAATAAAAATCGTCATAGTTAGTGCATAAAAGGATTCAACAAATGCAAGTG
AATCAAATATTTAAGATCGATTTTTATAGTGATAAAAAAGTAGAATTATATAAATTTTTA
TTGTATTATTAGGCCTTGATCAAGTTGATGGAACCTAAGGTTGAGTTAAAAGTAATGAAG
AAAGATTTGTAGCTTGCTCGTGAAGTAAAGACAGAATGTGAAAATGAATTCAAGGCAATT
GCTAAGAGAGAATGTAATAGAGACTTTAACTGTACTATTATTATAAATGAATACCACTCT
CTTGAAGAAGAAAATCCTAAAGTGTAAACAAATTCATCCAAAGCATTTACTTTATCAATA
TTATTACTATTATTTATTTAGTATTGGAGGTATTGTTCTCACTTGCGATGGTGGTAGAAT
TTAGGTAAACAACACTTTAAATGCAAGAGTTGATCTTGCTTTCTAAGAATTCCTTCCTGA
CATCAGAAGAATTCTTTTCCCTTCTATGAAATGA

>TTHERM_00193660(protein)
MADFINKPQENVQKIVEAIKSEAEEKAEQIKKNAEEQFKIQKNNIVNTEKDKIIEEYKKR
LEKLIVDRRIQRSAKINEQRLEKMKARFDFIEKLKGEISNKIVQSVSDPNKYKNVFKQLI
IQALIKLMEPKVELKVMKKDLQLAREVKTECENEFKAIAKRECNRDFNCTIIINEYHSLE
EENPKVIGGIVLTCDGGRIQVNNTLNARVDLAFQEFLPDIRRILFPSMK