Identifiers and Description

Gene Model Identifier

TTHERM_00242120

Standard Name

AAT1 (Aspartyl protease AcetylTransferase 1)

Aliases

PreTt18950 | 20.m00414 | 3706.m00178 | APAT1

Description

eukaryotic aspartyl protease

Genome Browser (Macronucleus)

Full Screen View


Genome Browser (Micronucleus)

Full Screen View

External Links

Gene Ontology Annotations

Molecular Function

Biological Process

Domains

  • ( PF00026 ) Eukaryotic aspartyl protease
  • ( PF00583 ) acetyltransferase, GNAT family
  • ( PF01657 ) Domain of unknown function
  • ( PF08445 ) FR47-like protein
  • ( TIGR01575 ) ribosomal-protein-alanine acetyltransferase
  • ( TIGR03065 ) sortase B signal domain, QVPTGV

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_07781.1 8.998537725811687e-130
Description: hypothetical protein (433 aa)
DictyBase DDB_G0279411 1.9991095569230066e-20
Description: ctsD on chromosome: 3 position 2104523 to 2105867
WormBase WBGene00000217 0.000000000000001999258566166494
Description: locus:asp-4 status:Confirmed UniProt:Q21966 protein_id:CAA90633.1
Oxytricha Contig20708.0.g67 0.000000000000008002679274403579
Description: Eukaryotic aspartyl protease
SGD YPL154C 0.000000000000020000882446601127
Description: PEP4 Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates
Stentor Coeruleus SteCoe_31827 0.0000000007582560427911907
Description: None

General Information

No. Gene Name(s) Paragraph Text
92 AAT1 APAT1 contains an Asp domain (E-value 3.9e-32). Proteins that contain this domains typically catalyze the transfer of acetyl groups and include pepsin-like aspartate proteases. APAT1 is likely to cut peptide bonds, take out the aspartyl group, and substitute it with an acetyl group. Paragraph by: Anna Cechony and Marzia Zendali (undergraduates), Keck Science Department, Scripps College.

Associated Literature

No Data fetched for Associated Literature

Sequences 

>TTHERM_00242120(coding)
ATGATTTTTTAAAATAGAAATTTTCTGCTACTTTTCTTAGGTTTTCTATCTTTATTTTCT
ATCATAAGCTCTAAAGAAGTTTAACTGATTAAGATTGATTTGGATAAAAATGAAAGAGAT
AATGAAAAAACTCTCTTATCATAAAGCTCAACTATCAATTTGTTAAATTAGGAAAATCTT
GCTTATGTTGGATTAGTATAAATTGGTACTCCTGCTTAAAATTTTTATGTTATATATGAT
ACAGGTTCTAATGATCTTTTTGTTTAATAATATGGTTGTTAAGGGTGTACAGTTACACCT
AGTTTAGGCTATACACCAAATGTCTATAAATCTTGGCTATCATCTACAAGCAGTGTTTCA
ACTAATAAAATATAGCTGAGTTATGGATCATTAACTGCATACGGATATAAAGGAAATGAA
AGTGTTTGGTTAAATGGGCACGCTGCAACTGCATTTAAAATGATATTTGTTTATCAAGAA
GGTAGTTCATAGTTTGGTAGTAAAAGTTCAGCTTTTGATGGTATAATGGGTTTGTCTAAT
GCCTAATCAAATATTAATATATTTGAATAAGGAAAATCGGAAGGAGTTTTAAATACTTCT
CTCTTTGCATTTGATTTAGCAAATAATAAATTTTACTATGATGATATCGATTAAAAATAT
CTCGATGCTCCATCAGTACCTTGTTCCATGGATGATAGATGGACATTCACAATTTTAGGC
CTTCATATTAATGGATAAGATTATACTGATAGTTTAAGCTCTTAAGATGGCTTAGTTGAC
TCAGGAACATCTTTGATTTATTTAAGCAATGGAGTTATATCTGCAATTGTAAATTCAAGT
AGTAAATTTTCAAGTAGACTTTAAGGAGCATATAGCTTAGATAATTGTGCTGGTTGCTTA
TGCTAAGAAATCAATTTTCTTCCTGTAATAGAATTTTATTCAAGAGGAGCTTTAATACTG
TTACCTCCTTCTTAGTACATGATGGTATATTCTTAATACTGTATATTGTCAATTTAAGAC
AGCTCATAATTCGGATTCAATCTTTTAGGTGATGCTTTTATGAGATAGCTAGTTGTTACA
TACAACAAATAAGATAATGAAATGACTTTCTATGGACCAAACAGCTCTTTTATGACTAAC
AAGAAAACTATACCAACTTTTATAGTTTTAACAGTATTTGCTGCATTAGGAATTTTAGCA
CTCCTTTTTGTTTCATATAGAGCTCATAAAGTTAAACAAAGTTTATATTACAATAACTCA
CCTTTAACTAGGAGATTAATTTGA


>TTHERM_00242120(gene)
ATGATTTTTTAAAATAGAAATTTTCTGCTACTTTTCTTAGGTTTTCTATCTTTATTTTCT
ATCATAAGTAAACTCTTTGCTATTATATTTTACTGCGCAAAATTCATTATAAATTATCAG
CAATTCCAATTATCATATTAAAATAGGCTCTAAAGAAGTTTAACTGATTAAGATTGATTT
GGATAAAAATGAAAGAGATAATGAAAAAACTCTCTTATCATAAAGCTCAACTATCAATTT
GTTAAATTAGGAAAATGTAATATAACTATTATAAATTTATAATGTATTAAATTTAAATTT
GAAATTTATTTACAGCTTGCTTATGTTGGATTAGTATAAATTGGTACTCCTGCTTAAAAT
TTTTATGTTATATATGATACAGGTTCTAATGTAATTATTTATTTACTTCAAATCTTTAAA
AATATACTCATTATTATAATAAATATAAGGATCTTTTTGTTTAATAATATGGTTGTTAAG
GGTGTACAGTTACACCTAGTTTAGGCTATACACCAAATGTCTATAAATCTTGGCTATCAT
CTACAAGCAGTGTTTCAACTAATAAAATATAGCTGAGTGTAATAAATCTTTTATTTTTAA
AGAATTTAACTAACTACAACTAAAAAATAAATAGTATGGATCATTAACTGCATACGGATA
TAAAGGAAATGAAAGTGTTTGGTTAAATGGGCACGCTGCAACTGCATTTAAAATGATATT
TGTTTATCAAGAAGGTAGTTCATAGTTTGGTAGTAAAAGTGTAATGAATTTACAATTTAA
TTTTGTTAGAAATTAAATTAGAATAACTAAAATGAAATTTAATTTTTTTTTTTTCCAAAC
AGTCAGCTTTTGATGGTATAATGGGTTTGTCTAATGCCTAATCAAATATTAATATATTTG
AATAAGGAAAATCGGAAGGAGTTTTAAATGTAATTTTTTACTTTACAATAGACTAAATAA
ATTGAAATATATTTCATAATTCAAAGACTTCTCTCTTTGCATTTGATTTAGCAAATAATA
AATTTTACTATGATGATATCGATTAAAAATATCTCGATGCTCCATCAGTACCTTGTTCCA
TGGATGATAGATGGGTAAATTTTTAATTTCTTGAGAAATTATAACAATTTTGATTTTATA
ATTTCTAATAGACATTCACAATTTTAGGCCTTCATATTAATGGATAAGATTATACTGATA
GTTTAAGCTCTTAAGATGGCTTAGTTGACTCAGGAACATCTTTGATTTATTTAAGCAATG
GTATTGAAATATAAACTAATAATATAATTAAATACTTTTACTATGACATTTTTTTTTAAA
AAACTATATCATTTTAAAAATATTATATTTTAATAAAACTAAAAGGAGTTATATCTGCAA
TTGTAAATTCAAGTAGTAAATTTTCAAGTAGACTTTAAGGAGCATATAGCTTAGATAATT
GTGCTGGTTGCTTATGCTAAGAAATCAATTTTCTTCCTGTAATAGAATTTTATTCAAGAG
GAGCTTTAATACTGTTACCTCCTTCTTAGTACATGATGGTATATTCTTAATACTGTATAT
TGTCAATTTAAGACAGCTCATAATTCGGATTCAATCTTTTAGGTGATGCTTTTATGAGAT
AGCTAGTTGTTACATACAACAAATAAGATAATGAAATGACTTTCTATGGGTATATTTTAA
ATAAATATAATTAATAGTATGTTTTATCAATTTAAATTTTAACTTAATAGACCAAACAGC
TCTTTTATGACTAACAAGAAAACTATACCAACTTTTATAGTTTTAACAGTATTTGCTGCA
TTAGGAATTTTAGCACTCCTTTTTGTTTCATATAGAGCTCATAAAGTTAAACAAAGTTTA
TATTACAATAACTCACCTTTAACTAGGAGATTAATTTGA


>TTHERM_00242120(protein)
MIFQNRNFLLLFLGFLSLFSIISSKEVQLIKIDLDKNERDNEKTLLSQSSTINLLNQENL
AYVGLVQIGTPAQNFYVIYDTGSNDLFVQQYGCQGCTVTPSLGYTPNVYKSWLSSTSSVS
TNKIQLSYGSLTAYGYKGNESVWLNGHAATAFKMIFVYQEGSSQFGSKSSAFDGIMGLSN
AQSNINIFEQGKSEGVLNTSLFAFDLANNKFYYDDIDQKYLDAPSVPCSMDDRWTFTILG
LHINGQDYTDSLSSQDGLVDSGTSLIYLSNGVISAIVNSSSKFSSRLQGAYSLDNCAGCL
CQEINFLPVIEFYSRGALILLPPSQYMMVYSQYCILSIQDSSQFGFNLLGDAFMRQLVVT
YNKQDNEMTFYGPNSSFMTNKKTIPTFIVLTVFAALGILALLFVSYRAHKVKQSLYYNNS
PLTRRLI