Identifiers and Description

Gene Model Identifier

TTHERM_00242270

Standard Name

FZY8 (FiZzY 8)

Aliases

PreTt18964 | 20.m00428 | 3706.m00192

Description

FZY8 cell cycle switch protein CCS52A; Fizzy/CDC20/CDH1 family protein; homolog of S. cerevisiae CDH1- a cell cycle regulated activator of the anaphase-promoting complex /cyclosome (APC/C)- which directs ubiquitination of various targets

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF00400 ) WD domain, G-beta repeat
• ( PF08662 ) Eukaryotic translation initiation factor eIF2A

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_07770.1	9.997093137033517e-262
	Description: hypothetical protein (838 aa)
Oxytricha	Contig4092.0.g70	6.996594825025754e-146
	Description: WD domain, G-beta repeat
WormBase	WBGene00001510	2.0006597401342834e-129
	Description: locus:fzr-1 status:Partially_confirmed UniProt:Q09649 protein_id:CAA87433.1
DictyBase	DDB_G0287259	3.999582750711782e-108
	Description: cdh1 on chromosome: 5 position 54882 to 57146
SGD	YGL003C	1.9992138342796362e-97
	Description: CDH1 Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p
Stentor Coeruleus	SteCoe_23149	2.138865964899539e-62
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00242270(coding)
ATGAATTGCCTTAGGAATCTATAAAACAGCAATCCTGCTAATAGAAAAGAAAGTCTTGAC
TACAGTCCTATAAATGAAAAAAAATCTAACTCTTAAAATGTAGAGAGCTAAAAATACCTT
TCTCCCTAACAGCTAGGGTAAAGCTATTCTACTTAGCCCAGTTTTAGAAGTCCTATGAGC
GGTGAGAACAGCAGTTGCTGCTAAAACTAATAATAAATCAGTTTTGTATAGCAAGCACAT
CCGTCTCTTCCTTGTTTTGAAGAAGAATTTGAATATTCGCCTGCTGAGGGTATTTGTACT
CCCTAAAATGGAAATAATAAAGATAGCACTACTAAATAATTATGCGAATAAGCATCTTCC
TTTTCTTAGAAATCAGAATACTCCATACAGCTCTTCAACTAGTAAACATTATTTAACTTT
TTACAAAAAATGAGATTTTAATTCAGCATCTTAATGCTAAAATCCTCACATAATTCTAAA
GCTTATGAACGATATTTCTATTTAAAAAATGAATTAAAGTTATAATCTTTAATGATATTA
AAAAATTTTTCTCTTTTAAATCTTAATGATTCAATGAATAAATATGTGAGTTGTATGAGT
ATTTTATTTAATATGAAAATATTTAATATTAGGTTGAGTGAATAATTCAGTAATATAAGC
TTAGAAGATCAAACAATAGGAAGTCCCTTGTAAAACAACAGCTCATACTTTTAAGAAAAA
TCTCAGAATAGTGAATAGAATTTTTACAATATGAGTGACACATTTTTAAATAGTACACAG
AATAGCAAGACTCCTTATGGAATTAGAAATTAATATATAGAAAACCCAGATATTGAGTTC
TTTTTGAAGAAAGGAATTATGAGTGCTCGCTATACTAATTCTAATGCTTTTGTCAAAAGA
AACGACCAATAATCTACACCTAAAGATCAGGATGGAATGGAAGAGAGTTTTGATGAGATT
ATTACTAAGTTTGATGAAGCATTGGAAGTTTCAGATTTTACTCAGAAGGTAAAATAAGAT
GATTTGGTGATGCAAATTCCTTTGTAAACTCCTAAAAGTCAAAGAAAATTAAAGGAAGAT
GACTGGAAAGAAAATTTTAGTTCTCCTGAGAGATTGAGTCTTTAGACAAGCTTATTTAGT
AAAAATAAAACATAATTTGATAATTAACTTTGCACTCTATCAAATAATAATTAAGCCATT
CCTAGCATTTGGAAAAGCTCTAAGTAGAAATTCAATAAAAAAAAATCTGATCGTTTTATT
CCTAATCGTAAAACATCAAAGTTATCTATTGCACTCACATCTGCGCATGAAATTAAAGAT
GAAAATGAAAACAAGAATTTCTTTAAAGGCGAATTTTACGATAAGTAATCTTAAGTTTCT
ATTGAAGAACTCTATAAATCTCACATTTTGGGAATATCAAACAATAATTAAAAAACTCCC
TTCGGTATTTCGTCTTCTTAATTTTCACAATATTTTGCAAACCATGGAAGTGCCATGATT
CCACCAAGATATGTAAACAATTCTTCCTAAGAAGTAGAGCGCTCAAATAATACTCCCCAC
TTACCAATTTACTTAAACCAAGACGAAAATGAAGTGTCTCAAACAATTCAGAGCTTCTCT
AATTAAAATATTTTAAGATTTAAGGATTCTCCTTAGAAGAACAAATAAGATATTGGAAAG
TTCCTACCTGAATATTCTAACAAGTATAGCTTAATTGATAATTAAAACTCTTGCATATTT
GATTTTAAGAGAAAAGAAACTCGTAAAATAAACAAAATTCCTTTTAAAGTTTTGGATGCA
CCATCACTATAAGACGACTTTTATCTAAACCTAGTAGATTGGTCTAGCACTAACATTTTA
GCTGTTGCTTTAGGTTCTTGCGTTTATCTGTGGAAGGCAGACAACAACAAGGTTATTAAA
TTTTGTGATTTAGGTTCTACAACTGTCACTAGTGTTGCATGGCATCCAAAAGGCCATCAA
CTTTCTCTTGGCACATCTGCTGGATAGGTCTAAGTCTGGGATGCGAACAGCTTAAAAATG
TTAAGATCCTACAATGATCATATTGTTAGAGTTGGTTCTCTTTCATGGTCAACGTCTCTT
TTAGCATGTGGTTCAAGAGATAAAACAATATCTCTTAGAGACTAAAGAGATGATAATTCA
ATAGTAAGAACATTTAAAGAACATAAATAAGAAGTCTGTGGACTGAAATGGAGTTTCGAC
GAGCAATACCTAGCTTCTGGTGGAAATGATAATAAATTATTTGTTTGGAATAATCACTCT
ACTATTCCCATTTGTAAATTTACTTAGCACACAGCTGCAGTGAAGGCAATAGCATGGTCT
CCACACTAGCATGGTTTACTTGCTTCTGGTGGTGGTACTCAAGATAGATGCATAAGATTC
TGGAATACATAAACAAGCACAATGCTCGATTATATAGACACTTAATCATAAGTTTGTAAT
TTAATGTTTGGCAAAACAGAAAATGAAATTGTGAGCACCCATGGATATTCGCTTAACTAA
ATAGTTGTTTGGAAATATCCTTCCTTACAAAAAATTGCAGAGCTTACTGGACACACATCT
AGAGTACTTTTCTTGGCAATGAGTCCCGATGGCTAAACAATAGTGACAGGAGCTGGAGAT
GAAACTCTGAGATTTTGGAAGGTTTTCCCTTCAGTAAATGATGGTTACAAACCCCCAAGT
GTATTAGTAAATGATATTAGAGATCTAAGATGA

>TTHERM_00242270(gene)
ATGAATTGCCTTAGGAATCTATAAAACAGCAATCCTGCTAATAGAAAAGAAAGTCTTGAC
TACAGTCCTATAAATGAAAAAAAATCTAACTCTTAAAATGTAGAGAGCTAAAAATACCTT
TCTCCCTAACAGCTAGGGTAAAGCTATTCTACTTAGCCCAGTTTTAGAAGTCCTATGAGC
GGTGAGAACAGCAGTTGCTGCTAAAACTAATAATAAATCAGTTTTGTATAGCAAGCACAT
CCGTCTCTTCCTTGTTTTGAAGAAGAATTTGAATATTCGCCTGCTGAGGGTATTTGTACT
CCCTAAAATGGAAATAATAAAGATAGCACTACTAAATAATTATGCGAATAAGCATCTTCC
TTTTCTTAGAAATCAGAATACTCCATACAGCTCTTCAACTAGTAAACATTATTTAACTTT
TTACAAAAAATGAGATTTTAATTCAGCATCTTAATGCTAAAATCCTCACATAATTCTAAA
GCTTATGAACGATATTTCTATTTAAAAAATGAATTAAAGTTATAATCTTTAATGATATTA
AAAAATTTTTCTCTTTTAAATCTTAATGATTCAATGAATAAATATGTGAGTTGTATGAGT
ATTTTATTTAATATGAAAATATTTAATATTAGGTTGAGTGAATAATTCAGTAATATAAGC
TTAGAAGATCAAACAATAGGAAGTCCCTTGTAAAACAACAGCTCATACTTTTAAGAAAAA
TCTCAGAATAGTGAATAGAATTTTTACAATATGAGTGACACATTTTTAAATAGTACACAG
AATAGCAAGACTCCTTATGGAATTAGAAATTAATATATAGAAAACCCAGATATTGAGTTC
TTTTTGAAGAAAGGAATTATGAGTGCTCGCTATACTAATTCTAATGCTTTTGTCAAAAGA
AACGACCAATAATCTACACCTAAAGATCAGGATGGAATGGAAGAGAGTTTTGATGAGATT
ATTACTAAGTTTGATGAAGCATTGGAAGTTTCAGATTTTACTCAGAAGGTAAAATAAGAT
GATTTGGTGATGCAAATTCCTTTGTAAACTCCTAAAAGTCAAAGAAAATTAAAGGAAGAT
GACTGGAAAGAAAATTTTAGTTCTCCTGAGAGATTGAGTCTTTAGACAAGCTTATTTAGT
AAAAATAAAACATAATTTGATAATTAACTTTGCACTCTATCAAATAATAATTAAGCCATT
CCTAGCATTTGGAAAAGCTCTAAGTAGAAATTCAATAAAAAAAAATCTGATCGTTTTATT
CCTAATCGTAAAACATCAAAGTTATCTATTGCACTCACATCTGCGCATGAAATTAAAGAT
GAAAATGAAAACAAGAATTTCTTTAAAGGCGAATTTTACGATAAGTAATCTTAAGTTTCT
ATTGAAGAACTCTATAAATCTCACATTTTGGGAATATCAAACAATAATTAAAAAACTCCC
TTCGGTATTTCGTCTTCTTAATTTTCACAATATTTTGCAAACCATGGAAGTGCCATGATT
CCACCAAGATATGTAAACAATTCTTCCTAAGAAGTAGAGCGCTCAAATAATACTCCCCAC
TTACCAATTTACTTAAACCAAGACGAAAATGAAGTGTCTCAAACAATTCAGAGCTTCTCT
AATTAAAATATTTTAAGATTTAAGGATTCTCCTTAGAAGAACAAATAAGATATTGGAAAG
TTCCTACCTGAATATTCTAACAAGTATAGCTTAATTGATAATTAAAACTCTTGCATATTT
GATTTTAAGAGAAAAGAAACTCGTAAAATAAACAAAATTCCTTTTAAAGTTTTGGATGCA
CCATCACTATAAGACGACTTTTATCTAAACCTAGTAGATTGGTCTAGCACTAACATTTTA
GCTGTTGCTTTAGGTTCTTGCGTTTATCTGTGGAAGGCAGACAACAACAAGGTTATTAAA
TTTTGTGATTTAGGTTCTACAACTGTCACTAGTGTTGCATGGCATCCAAAAGGCCATCAA
CTTTCTCTTGGCACATCTGCTGGATAGGTCTAAGTCTGGGATGCGAACAGCTTAAAAATG
TTAAGATCCTACAATGATCATATTGTTAGAGTTGGTTCTCTTTCATGGTCAACGTCTCTT
TTAGCATGTGGTTCAAGAGATAAAACAATATCTCTTAGAGACTAAAGAGATGATAATTCA
ATAGTAAGAACATTTAAAGAACATAAATAAGAAGTCTGTGGACTGAAATGGAGTTTCGAC
GAGCAATACCTAGCTTCTGGTGGAAATGATAATAAATTATTTGTTTGGAATAATCACTCT
ACTATTCCCATTTGTAAATTTACTTAGCACACAGCTGCAGTGAAGGCAATAGCATGGTCT
CCACACTAGCATGGTAATTATATATTTTTTTTTTTGAGTTTTAATTGATAAAAAACAATA
TAAATTTTAGGTTTACTTGCTTCTGGTGGTGGTACTCAAGATAGATGCATAAGATTCTGG
AATACATAAACAAGCACAATGCTCGATTATATAGACACTTAATCATAAGTTTGTAATTTA
ATGTTTGGCAAAACAGAAAATGAAATTGTGAGCACCCATGGATATTCGCTTAACTAAATA
GTTGTTTGGAAATATCCTTCCTTACAAAAAATTGCAGAGCTTACTGGACACACATCTAGA
GTACTTTTCTTGGCAATGAGTCCCGATGGCTAAACAATAGTGACAGGAGCTGGAGATGAA
ACTCTGAGATTTTGGAAGGTTTTCCCTTCAGTAAATGATGGTTACAAACCCCCAAGTGTA
TTAGTAAATGATATTAGAGATCTAAGATGA

>TTHERM_00242270(protein)
MNCLRNLQNSNPANRKESLDYSPINEKKSNSQNVESQKYLSPQQLGQSYSTQPSFRSPMS
GENSSCCQNQQQISFVQQAHPSLPCFEEEFEYSPAEGICTPQNGNNKDSTTKQLCEQASS
FSQKSEYSIQLFNQQTLFNFLQKMRFQFSILMLKSSHNSKAYERYFYLKNELKLQSLMIL
KNFSLLNLNDSMNKYVSCMSILFNMKIFNIRLSEQFSNISLEDQTIGSPLQNNSSYFQEK
SQNSEQNFYNMSDTFLNSTQNSKTPYGIRNQYIENPDIEFFLKKGIMSARYTNSNAFVKR
NDQQSTPKDQDGMEESFDEIITKFDEALEVSDFTQKVKQDDLVMQIPLQTPKSQRKLKED
DWKENFSSPERLSLQTSLFSKNKTQFDNQLCTLSNNNQAIPSIWKSSKQKFNKKKSDRFI
PNRKTSKLSIALTSAHEIKDENENKNFFKGEFYDKQSQVSIEELYKSHILGISNNNQKTP
FGISSSQFSQYFANHGSAMIPPRYVNNSSQEVERSNNTPHLPIYLNQDENEVSQTIQSFS
NQNILRFKDSPQKNKQDIGKFLPEYSNKYSLIDNQNSCIFDFKRKETRKINKIPFKVLDA
PSLQDDFYLNLVDWSSTNILAVALGSCVYLWKADNNKVIKFCDLGSTTVTSVAWHPKGHQ
LSLGTSAGQVQVWDANSLKMLRSYNDHIVRVGSLSWSTSLLACGSRDKTISLRDQRDDNS
IVRTFKEHKQEVCGLKWSFDEQYLASGGNDNKLFVWNNHSTIPICKFTQHTAAVKAIAWS
PHQHGLLASGGGTQDRCIRFWNTQTSTMLDYIDTQSQVCNLMFGKTENEIVSTHGYSLNQ
IVVWKYPSLQKIAELTGHTSRVLFLAMSPDGQTIVTGAGDETLRFWKVFPSVNDGYKPPS
VLVNDIRDLR