Identifiers and Description

Gene Model Identifier

TTHERM_00260770

Standard Name

NRK14 (NIMA-Related Kinase)

Aliases

PreTt29340 | 23.m00236

Description

NRK14 Serine/Threonine kinase domain protein; NIMA-Related Kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF04935 ) Surfeit locus protein 6
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_13672.1	3.0005221502158484e-68
	Description: protein kinase domain-containing protein (942 aa)
Oxytricha	Contig6078.0.1.g70	4.00060640795776e-64
	Description: Protein kinase domain
DictyBase	DDB_G0289277	1.999534248571833e-46
	Description: nek4 on chromosome: 5 position 2561379 to 2563106
WormBase	WBGene00021461	1.9991939848149086e-44
	Description: locus:nekl-1 status:Partially_confirmed UniProt:Q6AW07 protein_id:CCD69902.1
SGD	YPL203W	2.998863950472602e-38
	Description: TPK2 cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase
Stentor Coeruleus	SteCoe_30195	2.1705220113036395e-29
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00260770(coding)
ATGTCATCTCAAAATCAATAATCTAATCATTTTAATATACCAGACGGCTATCGATGGATT
AAAAAAATAGGCGAAGGTGCATATGGTTAAGTGCATTTGGTGTAAAGCATTAGAGATGGT
AGTAAATGGGCGATAAAAAATATATATGTTAGTGGAGGTGAAGATGTGAAAAAAAAACGC
TAATCTGAATACAAAATCCTTAAGAAGCTTGATAATCCTCATATAATTAAGTTCAAGGAG
GCTATTAATTATAGAAATTAATAATTGATTTAGATCATTATGGAATACACAGATGGTGGA
GACTTAGAAAAACTAATAGAAAAATAAAAATAAAGTGCAAAACCATTTGAAGAAGAGAAA
ATTTTAGATTTTTTTATTCAAATTTGCTTGGGCTTGGATTGCATACACAAAAATAAAATA
ATTCATAGAGATATCAAACCTGCAAATATATTTTTAACTGCTTTTGGTTAATTGAAAATT
GGTGATTTCGGAGTATCAAAAGAACTTTAATACACTAAATAATGTCTAAAAACAATAGTT
GGGACTCCGTACTATATAGCTCCAGAAATTGTAAGTGGATATGCATATAATTCAAGTGTT
GATATTTGGTCTTTAGGTGTTATTCTATATTAGCTGTGTTGTCTTTAACCACCTTTTTAA
GACTGGAATGAAGCAAATCTTTACTGTAAAATTAAAAAAAAACCCTATCCACCTATAGCT
TAACTTTATTACTCAGGAAAACTTAAAACATTAATATCTAAACTCCTGAGAAAATGCCCA
AAGGAACGCTATACTTTAAAATAAATATTCGACGAATCTTTAATTTAAAGTAGACTCAAA
GTATACTTAAAAAAATCCATTTTAAATAGATCTCCTGATATACCTTAGGTAAATAATTTT
ATGGAGCAAGACTCATTATTGAATCAATTCATATAGAATGATCACTTGTAAGAAAATAGA
TAAGAAATTAACCAATAACCTGTTAATAGCAATGTAAATTAATAAAATATCAATCCAACT
TCTGCTAATAACTAAAATTTCGAAAGTAATAATAATTAATTAAATGAGCTTAGGCCATAA
AGTTGTGCCAATAGGTAAGCTTAAGAAGAATAAAAAAATGAATCTGCTGATAGGAGAAAA
AACTTACAAAAACTTGACAAATAAGAGTAATCAAATTTAGAAGAAAAAAATGCACAGAAT
AATAATAATAATAATAATATAGAAAATAATACAATTCCAGCTAGTCCATAAGTAAAGAAT
TTTAACACTTTAAAAAATGAAAATAACACTCATCTAAGTGGAAAGAGTACTTCATAAAGT
AGTTAAATATCGGACTTAGAAACACCTGTCGCAGAGAAAAAGGTGTAGCATTGTCGATCA
TCAGTTATAATAAAAATTAAAAACATTACTGATTAGAGAAATGAGTAAAATCAAAAAAGT
TAAGATAACCCTTTTATTTTACCAAATCAATAATAAAATAAAAAAGATAATCTTTAGTAG
TTTAAATCAAAATCAGTTATTGTATTCAATGAAAGAGATTTCTTTTGTAATAAATAAATA
TTGCCACCTCTAACATAAATACAAAAAATAGAAATCGAAAAAGAAAATGTAAATCAAAAT
CATTTGAATGAAGATTTATAAAAATAAATTTAAGTAAACAGAAAATATGAAAACATATTT
AGTACACATTAAAAATAAATCAGTGGCTTAGATAAATAAAATATTCAATATGAAAAAAAA
ATAAAATCGAACCTCAATTAGGTTGATAAATTCCCAATAACTCCAACCAAACCAGATTAA
AAAGATTTGAACACAAAATAAAATGGTAATTCTTAAGAACAAAAAAATATTTCTAAAGCA
AAAAGAAATAATTTTAATGAATAAGAATTCAACACTCATTCTTGTTAATTATTGACCGGA
AAAAAAAAAAATTTTGTAGATAAGGAGCAGTCACAAGAGAAGAATTCCAAGGTTCTATTT
GAATAAAAAACTCAAAATATTTGTCTTGAGAAATAATCGTCTAAAAATAACATGATTAGA
GAGCTAAATTAATTTTAAGTACCTTATTCAGAAGATGAATACATCAAATACCTGACGTGT
TTAATTTAAAGTGAACCAAATTATGTCAAAGAAACCTATAATGAGGAAGATTTACTTTAG
GAAAATGATCTTAAACTAATAGATGATGAAGATTTTTATTATGATGATTACTTTGAAGAA
GAAGAAGAAGAAGTAGAAGAAGAAGAAAAAATAAATAAATAACAAGAAAGAGATGTAGAA
AAGATTTATAACATTCCAAGATAATCACAAGAATAATTTAATTAATTGAAGGAAGATTTC
TTTAAAAAAATGACACAAGAGTAATTCAAACTACTTTACAACATAGTAAATAAGGAGATG
TAAAATTAAGACTTCTTAGATGATACACTAAAGAACTAAATAAAGATATTATAAAAAAAG
ATTCTCTCAGTTGAACTAGATGAATTAAAGTATAAAATATAATAATTAATTTATCTATTA
AGTTAAGATTGA

>TTHERM_00260770(gene)
ATGTCATCTCAAAATCAATAATCTAATCATTTTAATATACCAGACGGCTATCGATGGATT
AAAAAAATAGGCGAAGGTGCATATGGTTAAGTGCATTTGGTGTAAAGCATTAGAGATGGT
AGTAAATGGGCGATAAAAAATATATATGTTAGTGGAGGTGAAGATGTGAAAAAAAAACGC
TAATCTGAATACAAAATCCTTAAGAAGCTTGATAATCCTCATATAATTAAGTTCAAGGAG
GCTATTAATTATAGAAATTAATAATTGATTTAGATCATTATGGAATACACAGATGGTAAA
TATTTAAAAATGTTATCTTGAAATGAAAGATATTTATTTCTTTTTTGCTTTTTTTATTAG
CTTATTTTTTAGATAATCTATAAAAACAAACCTCAATATTTAATTTATGTAATATTTGCA
ATCAAATATATAAAAAAATTAATAAATAAATATATAGGTGGAGACTTAGAAAAACTAATA
GAAAAATAAAAATAAAGTGCAAAACCATTTGAAGAAGAGAAAATTTTAGATTTTTTTATT
CAAATTTGCTTGGGCTTGGATTGCATACACAAAAAGTAAGTAGAAGAAATAAAATTATAG
TTTTATTTATTAAATAATCTTTTATAATAAAGTAAAATAATTCATAGAGATATCAAACCT
GCAAATATATTTTTAACTGCTTTTGGTTAATTGAAAATTGGTGATTTCGGAGTATCAAAA
GAACTTTAATACACTAAATAATGTCTAAAAACAATAGTTGGGACTCCGTACTATATAGCT
CCAGAAATTGTAAGTGGATATGCATATAATTCAAGTGTTGATATTTGGTCTTTAGGTGTT
ATTCTATATTAGCTGTGTTGTCTTTAACCACCTTTTTAAGACTGGAATGAAGCAAATCTT
TACTGTAAAATTAAAAAAAAACCCTATCCACCTATAGCTTAACTTTATTACTCAGGAAAA
CTTAAAACATTAATATCTAAACTCCTGAGAAAATGCCCAAAGGAACGCTATACTTTAAAA
TAAATATTCGACGAATCTTTAATTTAAAGTAGACTCAAAGTATACTTAAAAAAATCCATT
TTAGTAAATTAATATAAATTTTATTTATTAATTTTTAAGATATAATTTTTTTTTTCTTAT
TAATTTATAGAATAGATCTCCTGATATACCTTAGGTAAATAATTTTATGGAGCAAGACTC
ATTATTGAATCAATTCATATAGAATGATCACTTGTAAGAAAATAGATAAGAAATTAACCA
ATAACCTGTTAATAGCAATGTAAATTAATAAAATATCAATCCAACTTCTGCTAATAACTA
AAATTTCGAAAGTAATAATAATTAATTAAATGAGCTTAGGCCATAAAGTTGTGCCAATAG
GTAAGCTTAAGAAGAATAAAAAAATGAATCTGCTGATAGGAGAAAAAACTTACAAAAACT
TGACAAATAAGAGTAATCAAATTTAGAAGAAAAAAATGCACAGAATAATAATAATAATAA
TAATATAGAAAATAATACAATTCCAGCTAGTCCATAAGTAAAGAATTTTAACACTTTAAA
AAATGAAAATAACACTCATCTAAGTGGAAAGAGTACTTCATAAAGTAGTTAAATATCGGA
CTTAGAAACACCTGTCGCAGAGAAAAAGGTGTAGCATTGTCGATCATCAGTTATAATAAA
AATTAAAAACATTACTGATTAGAGAAATGAGTAAAATCAAAAAAGTTAAGATAACCCTTT
TATTTTACCAAATCAATAATAAAATAAAAAAGATAATCTTTAGTAGTTTAAATCAAAATC
AGTTATTGTATTCAATGAAAGAGATTTCTTTTGTAATAAATAAATATTGCCACCTCTAAC
ATAAATACAAAAAATAGAAATCGAAAAAGAAAATGTAAATCAAAATCATTTGAATGAAGA
TTTATAAAAATAAATTTAAGTAAACAGAAAATATGAAAACATATTTAGTACACATTAAAA
ATAAATCAGTGGCTTAGATAAATAAAATATTCAATATGAAAAAAAAATAAAATCGAACCT
CAATTAGGTTGATAAATTCCCAATAACTCCAACCAAACCAGATTAAAAAGATTTGAACAC
AAAATAAAATGGTAATTCTTAAGAACAAAAAAATATTTCTAAAGCAAAAAGAAATAATTT
TAATGAATAAGAATTCAACACTCATTCTTGTTAATTATTGACCGGAAAAAAAAAAAATTT
TGTAGAGTAAATTAATTGTGATGAAAGTTATTAAAATAATTTATTTTATCATAAAGTAAG
GAGCAGTCACAAGAGAAGAATTCCAAGGTTCTATTTGAATAAAAAACTCAAAGTAAATTA
AATTAAAAATATATTTTTTGAATTTAGTTTTTGTATATGAAGAAGATATTTGTCTTGAGA
AATAATCGTCTAAAAATAACATGATTAGAGAGCTAAATTAATTTTAAGTACCTTATTCAG
AAGATGAATACATCAAATACCTGACGTGTTTAGTATATTAAATTGTTTTAAAATAGCATT
TTGAAATAAACCATTGAATTTTATTTAGATTTAAAGTGAACCAAATTATGTCAAAGAAAC
CTATAATGAGGAAGATTTACTTTAGGAAAATGATCTTAAACTAATAGATGATGAAGATTT
TTATTATGATGATTACTTTGAAGAAGAAGAAGAAGAAGTAGAAGAAGAAGAAAAAATAAA
TAAATAACAAGAAAGAGATGTAGAAAAGATTTATAACATTCCAAGATAATCACAAGAATA
ATTTAATGTAGTTTTCATCAAAATTCCAATTTATATTTATTTATGTCCTATTCATAAATA
TAGTAATTGAAGGAAGATTTCTTTAAAAAAATGACACAAGAGTAATTCAAACTACTTTAC
AACATAGTAAATAAGGAGGTAAAATTAATTTAAAAATATTTTTAAAAGAAGAAAGTAATT
TTATTTTAAAAATTAGATGTAAAATTAAGACTTCTTAGATGATACACTAAAGAACTAAAT
AAAGATATTATAAAAAAAGATTCTCTCAGTTGAACTAGATGAATTAAAGTATAAAATATA
ATAATTAATTTATCTATTAAGTTAAGATTGA

>TTHERM_00260770(protein)
MSSQNQQSNHFNIPDGYRWIKKIGEGAYGQVHLVQSIRDGSKWAIKNIYVSGGEDVKKKR
QSEYKILKKLDNPHIIKFKEAINYRNQQLIQIIMEYTDGGDLEKLIEKQKQSAKPFEEEK
ILDFFIQICLGLDCIHKNKIIHRDIKPANIFLTAFGQLKIGDFGVSKELQYTKQCLKTIV
GTPYYIAPEIVSGYAYNSSVDIWSLGVILYQLCCLQPPFQDWNEANLYCKIKKKPYPPIA
QLYYSGKLKTLISKLLRKCPKERYTLKQIFDESLIQSRLKVYLKKSILNRSPDIPQVNNF
MEQDSLLNQFIQNDHLQENRQEINQQPVNSNVNQQNINPTSANNQNFESNNNQLNELRPQ
SCANRQAQEEQKNESADRRKNLQKLDKQEQSNLEEKNAQNNNNNNNIENNTIPASPQVKN
FNTLKNENNTHLSGKSTSQSSQISDLETPVAEKKVQHCRSSVIIKIKNITDQRNEQNQKS
QDNPFILPNQQQNKKDNLQQFKSKSVIVFNERDFFCNKQILPPLTQIQKIEIEKENVNQN
HLNEDLQKQIQVNRKYENIFSTHQKQISGLDKQNIQYEKKIKSNLNQVDKFPITPTKPDQ
KDLNTKQNGNSQEQKNISKAKRNNFNEQEFNTHSCQLLTGKKKNFVDKEQSQEKNSKVLF
EQKTQNICLEKQSSKNNMIRELNQFQVPYSEDEYIKYLTCLIQSEPNYVKETYNEEDLLQ
ENDLKLIDDEDFYYDDYFEEEEEEVEEEEKINKQQERDVEKIYNIPRQSQEQFNQLKEDF
FKKMTQEQFKLLYNIVNKEMQNQDFLDDTLKNQIKILQKKILSVELDELKYKIQQLIYLL
SQD