Identifiers and Description

Gene Model Identifier

TTHERM_00433390

Standard Name

CYC10 (CYClin 10)

Aliases

PreTt26482 | 48.m00245 | 3831.m01583

Description

CYC10 cyclin-dependent kinase-like protein; Cyclin- N-terminal domain containing protein; CDC2 subfamily of protein kinase CDK family; fusion of cyclin protein and cyclin-dependent kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• nucleus (IEA) | GO:0005634

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_04170.1	9.997093137033517e-262
	Description: cyclin domain-containing protein (1077 aa)
Oxytricha	Contig19750.0.g98	9.997093137033517e-262
	Description: Protein kinase domain
Stentor Coeruleus	SteCoe_26282	5.440559879258653e-75
	Description: None
DictyBase	DDB_G0272813	7.002411919958887e-50
	Description: cdk1 on chromosome: 2 position 2216835 to 2217926
WormBase	WBGene00000405	1.9990449803848145e-49
	Description: locus:cdk-1 Cyclin-dependent kinase 1 status:Confirmed UniProt:P34556 protein_id:CAA81590.1
SGD	YBR160W	7.00293386439118e-45
	Description: CDC28 Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternately associates with G1 cyclins (CLNs) and G2/M cyclins (CLBs) which direct the CDK to specific substrates

General Information

No Data fetched for General Information

Associated Literature

1. Ref:27192402: Yan GX, Dang H, Tian M, Zhang J, Shodhan A, Ning YZ, Xiong J, Miao W (2016) Cyc17, a meiosis-specific cyclin, is essential for anaphase initiation and chromosome segregation in Tetrahymena thermophila. Cell cycle (Georgetown, Tex.) 15(14):1855-64
2. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00433390(coding)
ATGTTTTAAAATACAAATTTCAACTGCAATCAGGAAGGTTAAAGTTAGAGAATTAATTCG
AATGTCTAGGGCTCAAGTGGTAAAGAGAGGAGATAACAGAACTAATCACAGAAGATGAAC
AATTAATAAAAAAATGAGTAGAGAAGCAAGTAAAAAAATAGACGTAGCAGTAGAAAATCT
TAGAGTAAGAATTCAAATAATAATGCTACATAGATAGAATAGCAAAACTAGTAATAAGAA
TTGATAAATAACTAAAGAGTAGAGAGCGCTTAAAATTCCAACAAAAAAATAGGATAATCT
ACCAATTCTACTTTATCGTCCTCCATTTAATCATCTCCTAGTTCTTATACTTCATAGTTT
CCTTCTATAAGTGAAATTACTTAGTTAACTGTCCTTAAAGGAAATTCAAATAATTATACA
AATAAAACTAATTTTTTAAGCTCTCCAAATGAAAATTCATACTAAGATTCACCTGCTTAA
AATCAATAGCAGCGAAGTGTTTCTCCTGTCAAAGAAGAGAGAAAGTATGATTCAGATGAT
CAAGAGAATAACCCAAGTCTTGCAAACTTATAAACAAGCAATACAAATAACTCCATAAAC
AATATCCAAAATAATAACAACATGAATATTCATATTAACTAAATGAATTAAAGTATCGCA
AGTAATAATAACTTAGGAATTTCAAATTTCATGAATGGCAACAGTAGCCAAAGCAATCAT
TTAAGCCACATTCACTAGCACCACTCACATAACTTACAGCAAATGTGCTGTCCTTTAAAT
AACAGTAGCAATTTGAACAGTATGATAAGCAGCAATAACTTTGATATTAATAACACTAGT
AGTTGTCATGAGAAATCTAGTTCAAAGCAGAGAAATGTAAATGGAAAAGGCAAAAAATAT
GGATATAAACATGGATAAATGAATCTGAACTGTGATTAAAATAGTTTGAATGGTAAAGAG
CAGCACAAAACATGCCAAATAAATTGCGAATAAGCACTATGCTAGAATAATAAAAGCTTA
AGAAATTTATCAAACTTACTAAAAAGCTTGAAATTTTCACCTCTACTTGCTTAATAATAG
TAAGTAACATAGAGCTTAATGACTTTACCCTTCGAACTTCACTTCATTATTTGTTCTTAT
TTATCTCCCAAAGATATTTACCTGCGCCTTGCAAATGTAAATTAGTACTTCCGTAAAATG
TGTAAAGATACTCGTCTTTGGAGCTATATCTAGAAGTTTTAGACTTTGACCATTAATGAC
AAATATTAGAAGAATATCCCTGTAGTAGAACGCAGATCCAAAGGAAGACTCTTTTCAGCA
GTATCCCGTCTAGATCATAATCAGTTTATGATTAGAAACGTGAACATTATGATAAGCAAT
GCTGGATAAGATGATGGAGTTCCTACTAGTATTTTAAGAGAACTCAGCTATTTGTAGGCT
CTTGATCACCCAAATATCACAAAAATTCACGAAGTAGACATAAAAAATGTGATAGTTCAA
ATAGTTACAAAAAGATAAGAGTATAACTTGAAGGAATATACAAGAAGATATATCAGCTAA
GTTCAGGATGACAGTAAGGGACTCACTCGTCCTCAATACAAAATTCCTTTGATTAAAGTT
AAGGAAATTGCTTACTAGATTCTTGAAGGTTTAAATTACTTGCATCACTAAGGAATTATG
CATAGAAATTTAAAGATTGATAATATTTTGCTTGATAAAGATGTTGTAAAAATATCAGAT
TTCGGTCTTTCAAGACTTGTTTCGATTCCCCACATACCATACACTCCTGAAGATCCTAAA
GAAAGAGAACGCTCAGGAAGAGAAGCTCGCCGTCTTTGGTACAGAGCTCCTGAGCTCCTT
TTGAGAAAAAGCATCTACACCTTTGAAATTGATATGTGGTCTTTTGGCTGTCTTTTAGCT
GAAATTGTTTTGAATGAACCTTTATTTGCTGGAGATTCTGAAATTGAGTAGCTTTTCAAG
GTATTCAAATTTATTGGTTCTCCAGATTCAGAAACCTTAATGTCAATGTGTGACAACCCT
GATTACTAGCAAACCTTCCCAAAATGGAAAATGATCAATTTATCCCATATCTGTGAATAA
AATTAGAGTGAAGAATTCAAATAATTAAAGACCACAATGATTCCCAACAGATAGAACGGA
TTTTAAAAACTTAAAAATTTAGGCACTATCTTGGGAATGTAAGGAATGTAGCTTTTGAAC
TCATTACTTCAATTAAATCCTTATAAGAGAATATCTTCTCAAGAGGCTCTTAACCATCCA
TTCTTCGATGAAATAAGATAGTAAAGAACTTTAATGAATATTCCCATGCAAATTGATGAA
ACCATTAATATTAATAAGTGTTGCAGCTAAGTAGTACCTTCATGCTATTTTTAGTTCTCA
CTACCTTACTGCCATTTATCAACAATTTATTAAACTATGGTTAAATAAGAAAAGATAGAA
ACCTTGATCAAACCTGATTACATGAAAGACTAAGCCTTAATCACTGAAAATATGCGTATA
ATACTTATTGATTGGCTAACTGATGTAAGCGTTCATTTCGAAGCATAAGACGAAACTCTT
CATTATTGTATTTCTTACATCGACAGAGCTTTGGGTATCATGAATATTGATAAACAAAAA
CTGCAGTTAGTAGGAGTAAGTTGCATGAAAATTGCAGATGTATTTAATGAGAGATCTAGA
GAATATTACAAATAAGAAAACGCTATCGAATATGCATACATAACAGCAGAAGAGTATAAT
GCAGCTTAACTCATTGCTATGGAGAAAAAAATTCTAAAAGTTCTCTCTTTCTAATTAAAT
ACTCCAAATATGATGTATTTTTTAAAAATAATGTGCACTTTATTTGATACTGACTCCTAG
GTTTCCGTTATTGCTATGTTCCTGGCCGACTTGCTACTTATGAGTTACGAAGCATTGAGA
TTTAAACCAAGCTTACTAGCCAGTTGCTGTATATTTTTGAGCTTTTTGACTAACGAGAGA
GAACTTCCTACTTAAGAAAAGCTAAATGAAGTTCGTAGCCTTTTAGACCATTATACTATT
AATGAGTTTAAAGAAGCAGCTGAATTTGTTAGAAAATTCTGGCATTATTATAGATCTGAT
CCCAACACACTAAACTTCTAATCAGTCTACAATAAGTATGCTGTTGTATATGGTCTAGAA
GCAAGACTAATTAATGCTCCTATAATAGAATAAGCCTAATACAGCTAATGGATCTATACA
AAATGA

>TTHERM_00433390(gene)
ATGTTTTAAAATACAAATTTCAACTGCAATCAGGAAGGTTAAAGTTAGAGAATTAATTCG
AATGTCTAGGGCTCAAGTGGTAAAGAGAGGAGATAACAGAACTAATCACAGAAGATGAAC
AATTAATAAAAAAATGAGTAGAGAAGCAAGTAAAAAAATAGACGTAGCAGTAGAAAATCT
TAGAGTAAGAATTCAAATAATAATGCTACATAGATAGAATAGCAAAACTAGTAATAAGAA
TTGATAAATAACTAAAGAGTAGAGAGCGCTTAAAATTCCAACAAAAAAATAGGATAATCT
ACCAATTCTACTTTATCGTCCTCCATTTAATCATCTCCTAGTTCTTATACTTCATAGTTT
CCTTCTATAAGTGAAATTACTTAGTTAACTGTCCTTAAAGGAAATTCAAATAATTATACA
AATAAAACTAATTTTTTAAGCTCTCCAAATGAAAATTCATACTAAGATTCACCTGCTTAA
AATCAATAGCAGCGAAGTGTTTCTCCTGTCAAAGAAGAGAGAAAGTATGATTCAGATGAT
CAAGAGAATAACCCAAGTCTTGCAAACTTATAAACAAGCAATACAAATAACTCCATAAAC
AATATCCAAAATAATAACAACATGAATATTCATATTAACTAAATGAATTAAAGTATCGCA
AGTAATAATAACTTAGGAATTTCAAATTTCATGAATGGCAACAGTAGCCAAAGCAATCAT
TTAAGCCACATTCACTAGCACCACTCACATAACTTACAGCAAATGTGCTGTCCTTTAAAT
AACAGTAGCAATTTGAACAGTATGATAAGCAGCAATAACTTTGATATTAATAACACTAGT
AGTTGTCATGAGAAATCTAGTTCAAAGCAGAGAAATGTAAATGGAAAAGGCAAAAAATAT
GGATATAAACATGGATAAATGAATCTGAACTGTGATTAAAATAGTTTGAATGGTAAAGAG
CAGCACAAAACATGCCAAATAAATTGCGAATAAGCACTATGCTAGAATAATAAAAGCTTA
AGAAATTTATCAAACTTACTAAAAAGCTTGAAATTTTCACCTCTACTTGCTTAATAATAG
TAAGTAACATAGAGCTTAATGACTTTACCCTTCGAACTTCACTTCATTATTTGTTCTTAT
TTATCTCCCAAAGATATTTACCTGCGCCTTGCAAATGTAAATTAGTACTTCCGTAAAATG
TGTAAAGATACTCGTCTTTGGAGCTATATCTAGAAGTTTTAGACTTTGACCATTAATGAC
AAATATTAGAAGAATATCCCTGTAGTAGAACGCAGATCCAAAGGAAGACTCTTTTCAGCA
GTATCCCGTCTAGATCATAATCAGGTAAAAAATAAATTGTCCTTCATTTTAAATTTTCTA
TTTCAAATTTTAAATCAATCAATCAATCAATCAACAAACATATTTGAAAACAAATTCTTG
GTTGAAAAAACCGAAACAGATTAATTCTTTTAAATTTTTGAACGAAATTCATTTTTTTAA
TGTTCAATTAAATTAAAAAAAAGTTTATGATTAGAAACGTGAACATTATGATAAGCAATG
CTGGATAAGATGATGGAGTTCCTACTAGTATTTTAAGAGAACTCAGCTATTTGTAGGCTC
TTGATCACCCAAATATCACAAAGTAATTTTAATTATTAATTCATTAACAAGTGAAAAACT
ACTAAATATTTATTCATTATTGTATTCTGCTCTTTTCAAATCAGAAAAAATTATCTTAAA
ATCATGGAGATTTTCATAAATAAACTGAAAAAATATTCTAAAATATTAAATTTTTATTTA
ATATAAAAATAGAATTCACGAAGTAGACATAAAAAATGTGATAGTTCAAATAGTTACAAA
AAGATAAGAGTATAACTTGAAGGAATATACAAGAAGATATATCAGCTAAGTTCAGGATGA
CAGTAAGGGACTCACTCGTCCTCAATACAAAATTCCTTTGATTAAAGTTAAGGAAATTGC
TTACTAGATTCTTGAAGGTTTAAATTACTTGCATCACTAAGGAATTATGCATAGAAATTT
AAAGATTGATAATATTTTGCTTGATAAAGATGTTGTAAAAATATCAGATTTCGGTCTTTC
AAGACTTGTTTCGATTCCCCACATACCATACACTCCTGAAGATCCTAAAGAAAGAGAACG
CTCAGGAAGAGAAGCTCGCCGTCTTTGGTACAGAGCTCCTGAGCTCCTTTTGAGAAAAAG
CATCTACACCTTTGAAATTGATATGTGGTCTTTTGGCTGTCTTTTAGCTGAAATTGTTTT
GAATGAACCTTTATTTGCTGGAGGTAAAAATAAATAAAATAAAAATTAATTTAAAACAAA
TAGAATTTTATACAAAATTTTTTTTGAGCATTTACAACTAATTAATTACAATTGTTTTTA
TGAAACTGATAGCAATCAATATATTAAATGTCTTTAAAAGCAGATAAATTTACAAATAAT
CTAGATTTAGGATAGCTTTCTAAATTAATATCAAGCATAAGTTAAAAACAGAAAATTTAA
ATTTGAATGCAAATTCATAAAATTAAGATATTAAGGCAACAAACAATTATCAATTTAATT
TATTTTATTTTTTGTTGTTTTTTTTCACTCAAAAAGAAAAATAGATAAAATAGACAAAAT
AAATGATTGATTTTCATCATATATAAAAATAATACTTGTTAAATTGAATTAGATCCATTC
AAATGACAAATAAATTGATTAATTCTTTTTATACTAAATAGATTCTGAAATTGAGTAGCT
TTTCAAGGTATTCAAATTTATTGGTTCTCCAGATTCAGAAACCTTAATGTCAATGTGTGA
CAACCCTGATTACTAGCAAACCTTCCCAAAATGGAAAATGATCAATTTATCCCATATCTG
TGAATAAAATTAGAGTGAAGAATTCAAATAATTAAAGACCACAATGATTCCCAACAGATA
GAACGGATTTTAAAAACTTAAAAATTTAGGCACTATCTTGGGAATGTAAGGAATGTAGCT
TTTGAACTCATTACTTCAATTAAATCCTTATAAGAGAATATCTTCTCAAGAGGCTCTTAA
CCATCCATTCTTCGATGAAATAAGATAGTAAAGAACTTTAATGAATATTCCCATGCAAAT
TGATGAAACCATTAATATTAATAAGTGTTGCAGCTAAGTAGTACCTTCATGCTATTTTTA
GTTCTCACTACCTTACTGCCATTTATCAACAATTTATTAAACTATGGTTAAATAAGAAAA
GATAGAAACCTTGATCAAACCTGATTACATGAAAGACTAAGCCTTAATCACTGAAAATAT
GCGTATAATACTTATTGATTGGCTAACTGATGTAAGCGTTCATTTCGAAGCATAAGACGA
AACTCTTCATTATTGTATTTCTTACATCGACAGGTAAATAAAAACCAAATCTTCTTATTT
TTTTTAAGTTATAATTTTATTTTTTAAAATAATTATTTTAATTAAACGTCTTTAATTAAT
CTTTACTAAATTAATGAATAATATTATAAATCAAAAGAGCTTTGGGTATCATGAATATTG
ATAAACAAAAACTGCAGTTAGTAGGAGTAAGTTGCATGAAAATTGCAGAGTAAGAAATTA
ATTTAATAATAAAGAATTTATTAATATTTAAAATTTAAAAATAGTGTATTTAATGAGAGA
TCTAGAGAATATTACAAATAAGAAAACGCTATCGAATATGCATACATAACAGCAGAAGAG
TATAATGCAGCTTAACTCATTGCTATGGAGAAAAAAATTCTAAAAGTTCTCTCTTTCTAA
TTAAATACTCCAAATATGATGTATTTTTTAAAAATAATGTGCACTTTATTTGATACTGAC
TCCTAGGTTTCCGTTATTGCTATGGTAAATTATTTATTAATAAAATAAATAAATCGTATA
AAAAATAAAAGCAAAAATTATACTGATTACTTTTTATTATGTTTTGCTTTTATTTTTTTC
AATATTATTTTAGTTTAAAATTTTTTGATTTTTAATTTAAATTTATATTTGAAAATTAAA
AGTTCCTGGCCGACTTGCTACTTATGAGTTACGAAGCATTGAGATTTAAACCAAGCTTAC
TAGCCAGTTGCTGTATATTTTTGAGCTTTTTGACTAACGAGAGAGAACTTCCTACTTAAG
AAAAGCTAAATGAAGTTCGTAGCCTTTTAGACCATTATACTATTAATGAGTTTAAAGAAG
CAGCTGAATTTGTTAGAAAATTCTGGCATTATTATAGATCTGATCCCAACACACTAAACT
TCTAATCAGTCTACAATAAGTATGCTGTTGTATATGGTCTAGAAGCAAGACTAATTAATG
CTCCTATAATAGAATAAGCCTAATACAGCTAATGGATCTATACAAAATGA

>TTHERM_00433390(protein)
MFQNTNFNCNQEGQSQRINSNVQGSSGKERRQQNQSQKMNNQQKNEQRSKQKNRRSSRKS
QSKNSNNNATQIEQQNQQQELINNQRVESAQNSNKKIGQSTNSTLSSSIQSSPSSYTSQF
PSISEITQLTVLKGNSNNYTNKTNFLSSPNENSYQDSPAQNQQQRSVSPVKEERKYDSDD
QENNPSLANLQTSNTNNSINNIQNNNNMNIHINQMNQSIASNNNLGISNFMNGNSSQSNH
LSHIHQHHSHNLQQMCCPLNNSSNLNSMISSNNFDINNTSSCHEKSSSKQRNVNGKGKKY
GYKHGQMNLNCDQNSLNGKEQHKTCQINCEQALCQNNKSLRNLSNLLKSLKFSPLLAQQQ
QVTQSLMTLPFELHFIICSYLSPKDIYLRLANVNQYFRKMCKDTRLWSYIQKFQTLTIND
KYQKNIPVVERRSKGRLFSAVSRLDHNQFMIRNVNIMISNAGQDDGVPTSILRELSYLQA
LDHPNITKIHEVDIKNVIVQIVTKRQEYNLKEYTRRYISQVQDDSKGLTRPQYKIPLIKV
KEIAYQILEGLNYLHHQGIMHRNLKIDNILLDKDVVKISDFGLSRLVSIPHIPYTPEDPK
ERERSGREARRLWYRAPELLLRKSIYTFEIDMWSFGCLLAEIVLNEPLFAGDSEIEQLFK
VFKFIGSPDSETLMSMCDNPDYQQTFPKWKMINLSHICEQNQSEEFKQLKTTMIPNRQNG
FQKLKNLGTILGMQGMQLLNSLLQLNPYKRISSQEALNHPFFDEIRQQRTLMNIPMQIDE
TININKCCSQVVPSCYFQFSLPYCHLSTIYQTMVKQEKIETLIKPDYMKDQALITENMRI
ILIDWLTDVSVHFEAQDETLHYCISYIDRALGIMNIDKQKLQLVGVSCMKIADVFNERSR
EYYKQENAIEYAYITAEEYNAAQLIAMEKKILKVLSFQLNTPNMMYFLKIMCTLFDTDSQ
VSVIAMFLADLLLMSYEALRFKPSLLASCCIFLSFLTNERELPTQEKLNEVRSLLDHYTI
NEFKEAAEFVRKFWHYYRSDPNTLNFQSVYNKYAVVYGLEARLINAPIIEQAQYSQWIYT
K