Identifiers and Description

Gene Model Identifier

TTHERM_00535810

Standard Name

YUH1 (Ubiquitin C-terminal hydrolase 1)

Aliases

PreTt03166 | 69.m00208 | 3718.m00070

Description

Ubiquitin carboxyl-terminal hydrolase; Ubiquitin carboxyl-terminal hydrolase- family 1 protein. Subunit of putative INO80-complex. Co-purifies with Hv1 (Kanwal Ashraf et al., 2019)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• intracellular anatomical structure (IEA) | GO:0005622

Molecular Function

• obsolete ubiquitin thiolesterase activity (IEA) | GO:0004221

Biological Process

• ubiquitin-dependent protein catabolic process (IEA) | GO:0006511

Domains

• ( PF01088 ) Ubiquitin carboxyl-terminal hydrolase, family 1

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_11159.1	9.997093137033517e-262
	Description: ubiquitin carboxyl-terminal hydrolase, family 1 protein (366 aa)
Oxytricha	Contig14629.0.g50	1.0000943968537097e-101
	Description: Ubiquitin carboxyl-terminal hydrolase, family 1
DictyBase	DDB_G0285527	3.9988176960464313e-94
	Description: uch2 on chromosome: 4 position 3345269 to 3346553
WormBase	WBGene00006724	1.0000521619018958e-77
	Description: locus:ubh-4 Probable ubiquitin carboxyl-terminal hydrolase ubh-4 status:Confirmed UniProt:Q09444 protein_id:CAA86665.2
Stentor Coeruleus	SteCoe_34120	3.0144087850653746e-40
	Description: None
SGD	YJR099W	0.0000000000599805963605737
	Description: YUH1 Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p

General Information

No Data fetched for General Information

Associated Literature

1. Ref:30796450: Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ):

Sequences

>TTHERM_00535810(coding)
ATGGGAGATTGGTGCACAATTGAGAGTGATCCAGGTGTTTTCACAGAACTCATTAGAGGT
ATTGGAGTAAAAGGTGTTTAAGTTGAAGAAGTTTACTCTTTAGAAGACTAATAACTCATT
TAATAGATTTAACCAATCTATGGTTTAGTTTTTCTCTTTAAGTGGACAGATAAACTAGAA
AAAAGAGAATGTCTTCTCAACTATGATAACGAACTCTTTTTCGCCAATCAAGTTATATAA
AATGCTTGCGCAACATAAGCTTTGCTGGCCATTTTGCTTAATAAAGATGATCAAATTGAT
ATAGGAGAGGATCTTAAAAATTTTAAAACATTTACTGCTACTTTAGACCCTCAAATGAAA
GGATTAGCCATTTCAAATTAAGAAAACATCTAAAGGGTCCACAACTCTTTCTCAAGACCA
GAACCCTTTATATTTACTTAATCCAAGAAGAAAGCAACTGAAAATGATGATGTTTTCCAT
TTTGTATCTTTTGTTCCTCATAAGGGTAAACTTTATGAACTTGATGGTCTTCAACAAGGT
CCTATTCTTTTAGGTTCTTACGAAAATGACGACTGGCTTACTCTTGCTACTTAAGAAATA
AATGCAAGAATTTTAAAATACAGCTAGGATGAAGTTAGATTTAATCTCCTCGCTTTAACT
ATTGACAAGCGTTATTAATGCTAAAATAACATAAAATAACTTGAACTTCAAAAACTTGGT
CTTTATCAGTATGCTAAAGATAACTAAGTCGAGTTGGATGCTATGTAGGAATCTGACTTT
GCTGATTTAAATGCAAAATTAAGTGAACAAGAAAAATTAGCTACTTAAGTCGATGCTTAA
GTAAATAAAGATATAGTTTTAGTCAAAATAGCAGATATCAATGATTAAATAGCCCAATAA
AAAATAATAATCGAAGAGGAAGAATACAAATTCAAAAAATATGAAGTAGAGAATGTGAGA
AGAAGACATAACTATATTCCATTTATTGTAGAGCTATTCAGATAGACAGCAAAAAAGGGC
AAACTTGCAGAATTGATTGAAAAAGCTAAATAAAAGAAAAAAGAAAAAGCATAATCATAG
TAATAATAATAAAAGAAAAACTGA

>TTHERM_00535810(gene)
ATGGGAGATTGGTGCACAATTGAGAGTGATCCAGGTGTTTTCACAGAACTCATTAGAGGT
ATTGGAGTAAAAGGTGTTTAAGTTGAAGAAGTTTACTCTTTAGAAGACTAATAACTCATT
TAATAGATTTAACCAATCTATGGTTTAGTTTTTCTCTTTAAGTGGACAGATAAACTAGAA
AAAAGAGAATGTCTTCTCAACTATGATAACGAACTCTTTTTCGCCAATCAAGTTATATAA
AATGCTTGCGCAACATAAGCTTTGCTGGCCATTTTGCTTAATAAAGATGATCAAATTGAT
ATAGGAGAGGATCTTAAAAATTTTAAAACATTTACTGCTACTTTAGACCCTCAAATGAAA
GGATTAGCCATTTCAAATTAAGAAAACATCTAAAGGGTAATTCTAATTCTAATTTATTTA
TCAATACTTATAAAATTAAGAAATTCATCTCAGTTTCTTAAAAGAAATCAATTCATTTTA
AAATATTTTTTATTGATCTAATATACAATTTTTTACAGTTTATTTTAATCTAATATCATA
TAGGTCCACAACTCTTTCTCAAGACCAGAACCCTTTATATTTACTTAATCCAAGAAGAAA
GCAACTGAAAATGATGATGTTTTCCATTTTGTATCTTTTGTTCCTCATAAGGGTAAACTT
TATGAACTTGATGGTCTTCAACAAGGTCCTATTCTTTTAGGTTCTTACGAAAATGACGAC
TGGCTTACTCTTGCTACTTAAGAAATAAATGCAAGAATTTTAAAGTATAATTTTTATTAA
AGTATTAGGGTTCAATAAATGATGCATTTTTTAAAAAAATAGATACAGCTAGGATGAAGT
TAGATTTAATCTCCTCGCTTTAACTATTGACAAGCGTTATTAAGTAAATATTTCTTTCAA
TAATTTGAATTTGTATCTTTAAATATTTTATCTAATAATTAGTGCTAAAATAACATAAAA
TAACTTGAACTTCAAAAACTTGGTCTTTATCAGTATGCTAAAGATAACTAAGTCGAGTTG
GATGCTATGTAGGAATCTGACTTTGCTGATTTAGTATAAAAAATTTAATACTTTCATTAA
AAAATTAATAAAATATTATAACTAATAGAATGCAAAATTAAGTGAACAAGAAAAATTAGC
TACTTAAGTCGATGCTTAAGTAAATAAAGATATAGTTTTAGTCAAAATAGCAGATATCAA
TGATTAAATAGCCCAATAAAAAATAATAATCGAAGAGGAAGAATACAAATTCAAAAAATA
TGAAGTAAAAATGCCTTTATAGTATTTATAAAAAATATTTAAAATAAAATTTAAATAAAT
AGGTAGAGAATGTGAGAAGAAGACATAACTATATTCCATTTATTGTAGAGCTATTCAGAT
AGACAGCAAAAAAGGGCAAACTTGCAGAATTGATTGAAAAAGCTAAATAAAAGAAAAAAG
AAAAAGCATAATCATAGTAATAATAATAAAAGAAAAACTGA

>TTHERM_00535810(protein)
MGDWCTIESDPGVFTELIRGIGVKGVQVEEVYSLEDQQLIQQIQPIYGLVFLFKWTDKLE
KRECLLNYDNELFFANQVIQNACATQALLAILLNKDDQIDIGEDLKNFKTFTATLDPQMK
GLAISNQENIQRVHNSFSRPEPFIFTQSKKKATENDDVFHFVSFVPHKGKLYELDGLQQG
PILLGSYENDDWLTLATQEINARILKYSQDEVRFNLLALTIDKRYQCQNNIKQLELQKLG
LYQYAKDNQVELDAMQESDFADLNAKLSEQEKLATQVDAQVNKDIVLVKIADINDQIAQQ
KIIIEEEEYKFKKYEVENVRRRHNYIPFIVELFRQTAKKGKLAELIEKAKQKKKEKAQSQ
QQQQKKN