Identifiers and Description

Gene Model Identifier

TTHERM_00568050

Standard Name

HMGB6 (High mobility group box protein 6)

Aliases

PreTt10434 | 76.m00136 | 3810.m01998

Description

high mobility group (HMG)-box protein; HMG box family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• nucleus (IEA) | GO:0005634

Molecular Function

• DNA binding (IEA) | GO:0003677

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_03499.1	3.999324360634196e-166
	Description: HMG box family protein (544 aa)
SGD	YKL032C	0.00000000009001903211590313
	Description: IXR1 Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b

General Information

No Data fetched for General Information

Associated Literature

1. Ref:31932604: Nabeel-Shah S, Ashraf K, Saettone A, Garg J, Derynck J, Lambert JP, Pearlman RE, Fillingham J (2020) Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila. Scientific reports 10(1):168

Sequences

>TTHERM_00568050(coding)
ATGCCAGGCAATGATGATGATGATGGATTTGATGACTTCATTAATTAATTGAAGGAAAAA
AAGGAGCATTTAAAAGTGAAATTATAGGGAGGAAGCGAAGAAATTCGCAAGCCCAAAAAG
CCATTAACTATCTTTTTAAGATTCCACATGGAGAAGTTTAATTAAATAAAAATGAAAAAT
CAAGATTGGACACCTAATATGATAACTCAATATTTAAAGAAGCAATGGGAGAGCATGAGT
GAGGCTTAAAAAGAAAGATATATCTAGACCTACGAATAGGATTTTAAAAAGTATAATAAG
TTAATTGACCTTTACAACAAGCTCACTCTTAAACCTAAGAAACCTATTACTCCTTATTTT
TAATTTTTTTCTGAAAATATTGAAGTATATTTAAAGAATTACCCTGAAAAATCGCATAAT
GAAATCACTAAATTGATTGGAGATGATTGGAATAATTTTGATTCCAAAAAAAAAAGTGAG
ATGAAAAAAGATTATGAAAAATAGAAGCAACTTTATGAAGTCTAGTTACAAAAATTTAAG
TAAAGAGAAAATAACTATATAAAATATGATGACTATAATCAAAAACTAGAAGATTATGAA
AAGGAGTTAGAAGAAGAATTAGATAATATCCGTTCTAAATTCCCAAAAGTTGCATCAACC
ATTCCAAAAAAGAAAAATTAGAAATAGAATTCAAAAGATAAATAAAATTTAAAGGATGAA
AAACAACAATAGAAGGATGAAAGCGAACAAGAATAGGAAGATCTTGAAGTGAAAATTGAA
GAAGAAGACGAACAAGGTTTAGATAAAGAAGATGAGGATGAAGGATAAGAAGAAGAAGAA
AATTTATCAAATGAAAGTGATTAAAAAAGAAATAAAAGCAAATCAAAAAGTAAGAAAGTT
TAAAAGGAGACCTAAAAAGCTTCAAATAATAAAAGAGAGTAAAAAGAGTAAAAGTTAAAA
GAAAAATCAGATAATAAAATAGATAAAGCCATTAAAGCAGCATAAGAAGAGGGCAGATCA
GGATTAAGAAAGAGGGAAGCAACTAAATAAACTAAAACTTAAGAAAATGAAAATAAATAA
GTAGAAAGAAGTGTATCTAAATCCTTAAAAACAAGATCATCTTCTAAAAAAGCATAAGAG
CATACTAAAATGAAAAGATCAAGATCTTAAATTGCACTTAAACAGTAATAAGAAAAAGAG
GAATCAAGTAAATAAGTGCCATAAGTAGCTAAAAGATCATCATCTTAATAGTCTTAAAAT
GTTACTTCTAAAGATAGTTAACAAAAAAAAACAAAGAATTAGGAAGCATCCAGATCTTCA
ACTAGAATTAAAGAGTAGAAGCTCAATGTAAAGAAAGAAGCATCAAAAAAGGTTGAAAAT
GATAAAAAGAAAGATGAAAAGAAAAAAGAAGTTTAAAGAGAAAGTTTAAAAAATATAAAA
ATCTTAAAAAGAAAGAATAAAGATAGAGATGCACAAGATGATGAAGTAGAAGAAGATATC
GAAGAGACTGTTCAAAAAAAATAAAAACTTGTTCAAGAAAAAATTATCACACACATATTA
GGAATGAGAGAATATAGAGGCAAAGTTAAATATTTATTAAGATTGAAAAATGATGAGTAA
TACTGGGCTAAGAGAGATGATCCTATTTTTAACGAAAATAAAAACCAATAAAAGTTGTCT
GTATTCTTAAAGTAAATTAAAAAACAAAAAAAGTGA

>TTHERM_00568050(gene)
ATGCCAGGCAATGATGATGATGATGGATTTGATGACTTCATTAATTAATTGAAGGAAAAA
AAGGAGCATTTAAAAGTGAAATTATAGGGAGGAAGCGAAGAAATTCGCAAGCCCAAAAAG
CCATTAACTATCTTTTTAAGATTCCACATGGAGAAGTTTAATTAAATAAAAATGAAAAAT
CAAGATTGGACACCTAATATGATAACTCAATATTTAAAGAAGCAATGGGAGAGCATGAGT
GAGGCTTAAAAAGAAAGATATATCTAGACCTACGAATAGGATTTTAAAAAGTATAATAAG
TTAATTGACCTTTACAACAAGCTCACTCTTAAACCTAAGAAACCTATTACTCCTTATTTT
TAATTTTTTTCTGAAAATATTGAAGTATATTTAAAGAATTACCCTGAAAAATCGCATAAT
GAAATCACTAAATTGATTGGAGATGATTGGAATAATTTTGATTCCAAAAAAAAAAGTGAG
ATGAAAAAAGATTATGAAAAATAGAAGCAACTTTATGAAGTCTAGTTACAAAAATTTAAG
TAAAGAGAAAATAACTATATAAAATATGATGACTATAATCAAAAACTAGAAGATTATGAA
AAGGAGTTAGAAGAAGAATTAGATAATATCCGTTCTAAATTCCCAAAAGTTGCATCAACC
ATTCCAAAAAAGAAAAATTAGAAATAGAATTCAAAAGATAAATAAAATTTAAAGGATGAA
AAACAACAATAGAAGGATGAAAGCGAACAAGAATAGGAAGATCTTGAAGTGAAAATTGAA
GAAGAAGACGAACAAGGTTTAGATAAAGAAGATGAGGATGAAGGATAAGAAGAAGAAGAA
AATTTATCAAATGAAAGTGATTAAAAAAGAAATAAAAGCAAATCAAAAAGTAAGAAAGTT
TAAAAGGAGACCTAAAAAGCTTCAAATAATAAAAGAGAGTAAAAAGAGTAAAAGTTAAAA
GAAAAATCAGATAATAAAATAGATAAAGCCATTAAAGCAGCATAAGAAGAGGGCAGATCA
GGATTAAGAAAGAGGGAAGCAACTAAATAAACTAAAACTTAAGAAAATGAAAATAAATAA
GTAGAAAGAAGTGTATCTAAATCCTTAAAAACAAGATCATCTTCTAAAAAAGCATAAGAG
CATACTAAAATGAAAAGATCAAGATCTTAAATTGCACTTAAACAGTAATAAGAAAAAGAG
GAATCAAGTAAATAAGTGCCATAAGTAGCTAAAAGATCATCATCTTAATAGTCTTAAAAT
GTTACTTCTAAAGATAGTTAACAAAAAAAAACAAAGAATTAGGAAGCATCCAGATCTTCA
ACTAGAATTAAAGAGTAGAAGCTCAATGTAAAGAAAGAAGCATCAAAAAAGGTTGAAAAT
GATAAAAAGAAAGATGAAAAGAAAAAAGAAGTTTAAAGAGAAAGTTTAAAAAATATAAAA
ATCTTAAAAAGAAAGAATAAAGATAGAGATGCACAAGATGATGAAGTAGAAGAAGATATC
GAAGAGACTGTTCAAAAAAAATAAAAACTTGTTCAAGAAAAAATTATCACACACATATTA
GGAATGAGAGAATATAGAGGCAAAGTTAAATATTTATTAAGATTGAAAAATGATGAGTAA
TACTGGGCTAAGAGAGATGATCCTATTTTTAACGAAAATAAAAACCAATAAAAGTTGTCT
GTATTCTTAAAGTAAATTAAAAAACAAAAAAAGTGA

>TTHERM_00568050(protein)
MPGNDDDDGFDDFINQLKEKKEHLKVKLQGGSEEIRKPKKPLTIFLRFHMEKFNQIKMKN
QDWTPNMITQYLKKQWESMSEAQKERYIQTYEQDFKKYNKLIDLYNKLTLKPKKPITPYF
QFFSENIEVYLKNYPEKSHNEITKLIGDDWNNFDSKKKSEMKKDYEKQKQLYEVQLQKFK
QRENNYIKYDDYNQKLEDYEKELEEELDNIRSKFPKVASTIPKKKNQKQNSKDKQNLKDE
KQQQKDESEQEQEDLEVKIEEEDEQGLDKEDEDEGQEEEENLSNESDQKRNKSKSKSKKV
QKETQKASNNKREQKEQKLKEKSDNKIDKAIKAAQEEGRSGLRKREATKQTKTQENENKQ
VERSVSKSLKTRSSSKKAQEHTKMKRSRSQIALKQQQEKEESSKQVPQVAKRSSSQQSQN
VTSKDSQQKKTKNQEASRSSTRIKEQKLNVKKEASKKVENDKKKDEKKKEVQRESLKNIK
ILKRKNKDRDAQDDEVEEDIEETVQKKQKLVQEKIITHILGMREYRGKVKYLLRLKNDEQ
YWAKRDDPIFNENKNQQKLSVFLKQIKKQKK