Identifiers and Description

Gene Model Identifier

TTHERM_00621200

Standard Name

IMA2 (IMportin Alpha 2)

Aliases

PreTt05117 | 86.m00149

Description

IMA2 armadillo/beta-catenin repeat protein; Armadillo/beta-catenin-like repeat family protein; Karyopherin/Importin alpha family member

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• micronucleus (IDA) | GO:0031040

Biological Process

• regulation of protein import into nucleus (IDA) | GO:0042306

Domains

• ( PF00514 ) Armadillo/beta-catenin-like repeat
• ( PF02985 ) HEAT repeat

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_03063.1	9.997093137033517e-262
	Description: armadillo/beta-catenin repeat family protein (583 aa)
DictyBase	DDB_G0272318	3.999672240330216e-26
	Description: DDB_G0272318 on chromosome: 2 position 1278811 to 1280712
Oxytricha	Contig20249.0.g40	1.0002869940498747e-21
	Description: Armadillo/beta-catenin-like repeat
SGD	YNL189W	7.998763385146868e-21
	Description: SRP1 Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation
WormBase	WBGene00002074	0.00000000000001000191320216021
	Description: locus:ima-3 Importin subunit alpha-3 status:Confirmed UniProt:Q19969 protein_id:CCD70435.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:18676955: Malone CD, Falkowska KA, Li AY, Galanti SE, Kanuru RC, LaMont EG, Mazzarella KC, Micev AJ, Osman MM, Piotrowski NK, Suszko JW, Timm AC, Xu MM, Liu L, Chalker DL (2008) Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryotic cell 7(9):1487-99

Sequences

>TTHERM_00621200(coding)
ATGGATATTGGATAAGACGAGGCACAACTGGTATTGTAGCATAAAAAAGATTAGTTTAGA
GTAGAGATTCGTAAGAAAAAGACAGATAGTTTAATATAGTAGAAAAGATTAAAGCTATTT
AATAAGAATTTAACAAATTTAGATAGCTTTTCTGATGCTGACAACAGTAAAAGCGATCAG
AATACTACTCAAGATCCTTAGAACAACATTTTAAGTTAACAACAAATTTAACAATAATAA
GTGTCTACTTTAGATGTTTAAGTCATTCGTGATATAGAAAGTAGGCTTTTGCAATGTTAG
AAAGATAATAATATAGAATAAATGAGATCTATTTTAATTCAGCTCGTTAAAATTGTTGGA
ACTTACCCATCACCAATAAATTAAATGTTTATGACAAGCTTACCTAAATTTGTAATTTCT
ATTGTTAATAAGCATGGCCCAGTAAATGATCCTAAATGTAAAAATTATGCTGCTCACATC
TTGGCAAATCTCACTGCAGGTACTCCTATGTAGTTGTAAGAACTTTTTTAGCTAGATTTG
ATTCACATCTTAATAGAGTAAATCCAATCCAAGGATGTAGAGTTAGCAGATCATGTCATT
TGGGCTTTTAATAATGTCTTGATTGATAATCATTAACCAGAGAACCTTGTAAGAATATTC
TAAGAGCGCCCTTTGATAATTGAAGATTTGTGCTATTATTTCACCACTTCTTGTAATAAT
CCAAATATCTAGTTTTAGCTTATTAGCTCAGTAATTCTTTCGATTTACTGTCTTTCTAGA
ATCCATAAAACTACTTAATCATATTATAATTAATTGAGGATTGCTATCCCATATCTAGCA
AAATTATTAGATGTCCATCATCCAAAAGAACCAAACACAGTAATAAATAGCATGTCTTCG
CTCCCTAATAAAAATAAATCAATGATTTTGAGCAATAATAGCAATTAGAATTAAATGAAT
TCCGAAAATTGTAAACCAACTAATTTATAAAGCACAAATAGTAATATCTAAAAAAGTGAC
TAGCAAGTTAAGTAAAAATTTCTCTGTTCTGTAGATTTAAAAATGTGCGCTCTTATAATA
ACGGATTTAAGTGAAGGTGATCCAAGAGTTATTAGCGATATGCTTAAAATTTAAGTTGAT
AGAATTATGCTTAGATATTTAGAGTAGGGAATTGATGTTAATGAGCATTTCCTCACCTTT
GTAATAAGAACTCTAGCCAACATGTCTAGTGGAAACGAGTTTCAAACTGACTAACTTCTC
TAAAAGGATATTTATTCATATCTGAACAGATTTTTGGAACATCCAAAAGAATAGATCAGA
AAAGATGTTTGTTGGCTAATAAGCAATTTGTCAGCAGGAAATGCTTCTCAAATAGATGTA
TTTTTAAATAAGAATATGCTTTAAACTTTGATTCAAAGACTTAACGTAGAGTAGAGCATA
CATGTAAAAAAAGAGATACTGTTTGCTCTGAGTAACGCAACTGCACAAGCAACAAAAGAA
CAAATAAATAAAATGGTTTCTAATGGTTTATTGAGAGTTTTTTCAGATAACCTCGACCCC
TAGTATGAAACTGAATTGCTTATTGAAATTTTAGAAGGAATAGAAAATGTAATGATGTTA
GGTCGTTCTGATGACCTCAATAATAATTAAAATGCATATAGCCATGAATTTGAAGGATCT
GGATGTTAAAGAAAAATCCAATATTTATATTACTAAAAATCAGACCAAACAGTAGTTGAA
ATTTCTGATAGAATACTCCGTTCATATGGAACTAATTGA

>TTHERM_00621200(gene)
ATGGATATTGGATAAGACGAGGCACAACTGGTATTGTAGCATAAAAAAGATTAGTTTAGA
GTAGAGATTCGTAAGAAAAAGACAGATAGTTTAATATAGTAGAAAAGATTAAAGCTATTT
AATAAGAATTTAACAAATTTAGATAGCTTTTCTGATGCTGACAACAGTAAAAGCGATCAG
AATACTACTCAAGATCCTTAGAACAACATTTTAAGTTAACAACAAATTTAACAATAATAA
GTGTCTACTTTAGATGTTTAAGTCATTCGTGATATAGAAAGTAGGCTTTTGCAATGTTAG
AAAGATAATAATATAGAATAAATGAGATCTATTTTAATTCAGCTCGTTAAAATTGTTGGA
ACTTACCCATCACCAATAAATTAAATGTTTATGACAAGCTTACCTAAATTTGTAATTTCT
ATTGTTAATAAGCATGGCCCAGTAAATGATCCTAAATGTAAAAATTATGCTGCTCACATC
TTGGCAAATCTCACTGCAGGTACTCCTATGTAGTTGTAAGAACTTTTTTAGCTAGATTTG
ATTCACATCTTAATAGAGTAAATCCAATCCAAGGATGTAGAGTTAGCAGATCATGTCATT
TGGGCTTTTAATAATGTCTTGATTGATAATCATTAACCAGAGAACCTTGTAAGAATATTC
TAAGAGCGCCCTTTGATAATTGAAGATTTGTGCTATTATTTCACCACTTCTTGTAATAAT
CCAAATATCTAGTTTTAGCTTATTAGCTCAGTAATTCTTTCGATTTACTGTCTTTCTAGA
ATCCATAAAACTACTTAATCATATTATAATTAATTGAGGATTGCTATCCCATATCTAGCA
AAATTATTAGATGTCCATCATCCAAAAGAACCAAACACAGTAATAAATAGCATGTCTTCG
CTCCCTAATAAAAATAAATCAATGATTTTGAGCAATAATAGCAATTAGAATTAAATGAAT
TCCGAAAATTGTAAACCAACTAATTTATAAAGCACAAATAGTAATATCTAAAAAAGTGAC
TAGCAAGTTAAGTAAAAATTTCTCTGTTCTGTAGATTTAAAAATGTGCGCTCTTATAATA
ACGGATTTAAGTGAAGGTGATCCAAGAGTTATTAGCGATATGCTTAAAATTTAAGTTGAT
AGAATTATGCTTAGATATTTAGAGTAGGGAATTGATGTTAATGAGCATTTCCTCACCTTT
GTAATAAGAACTCTAGCCAACATGTCTAGTGGAAACGAGTTTCAAACTGACTAACTTCTC
TAAAAGGATATTTATTCATATCTGAACAGATTTTTGGAACATCCAAAAGAATAGATCAGA
AAAGATGTTTGTTGGCTAATAAGCAATTTGTCAGCAGGAAATGCTTCTCAAATAGATGTA
TTTTTAAATAAGAATATGCTTTAAACTTTGATTCAAAGACTTAACGTAGAGTAGAGCATA
CATGTAAAAAAAGAGATACTGTTTGCTCTGAGTAACGCAACTGCACAAGCAACAAAAGAA
CAAATAAATAAAATGGTTTCTAATGGTTTATTGAGAGTTTTTTCAGATAACCTCGACCCC
TAGTATGAAACTGAATTGCTTATTGAAATTTTAGAAGGAATAGAAAATGTAATGATGTTA
GGTCGTTCTGATGACCTCAATAATAATTAAAATGCATATAGCCATGAATTTGAAGGATCT
GGATGTTAAAGAAAAATCCAATATTTATATTACTAAAAATCAGACCAAACAGTAGTTGAA
ATTTCTGATAGAATACTCCGTTCATATGGAACTAATTGA

>TTHERM_00621200(protein)
MDIGQDEAQLVLQHKKDQFRVEIRKKKTDSLIQQKRLKLFNKNLTNLDSFSDADNSKSDQ
NTTQDPQNNILSQQQIQQQQVSTLDVQVIRDIESRLLQCQKDNNIEQMRSILIQLVKIVG
TYPSPINQMFMTSLPKFVISIVNKHGPVNDPKCKNYAAHILANLTAGTPMQLQELFQLDL
IHILIEQIQSKDVELADHVIWAFNNVLIDNHQPENLVRIFQERPLIIEDLCYYFTTSCNN
PNIQFQLISSVILSIYCLSRIHKTTQSYYNQLRIAIPYLAKLLDVHHPKEPNTVINSMSS
LPNKNKSMILSNNSNQNQMNSENCKPTNLQSTNSNIQKSDQQVKQKFLCSVDLKMCALII
TDLSEGDPRVISDMLKIQVDRIMLRYLEQGIDVNEHFLTFVIRTLANMSSGNEFQTDQLL
QKDIYSYLNRFLEHPKEQIRKDVCWLISNLSAGNASQIDVFLNKNMLQTLIQRLNVEQSI
HVKKEILFALSNATAQATKEQINKMVSNGLLRVFSDNLDPQYETELLIEILEGIENVMML
GRSDDLNNNQNAYSHEFEGSGCQRKIQYLYYQKSDQTVVEISDRILRSYGTN