Identifiers and Description

Gene Model Identifier

TTHERM_00641210

Standard Name

IXR1 (Intrastrand crosslink recognition protein)

Aliases

PreTt10589 | 92.m00131

Description

High mobility group (HMG) box protein; HMG box family protein. Homologue of Yeast IXR1 (Nabeel-Shah et al., 2020)

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Domains

  • ( PF00505 ) HMG (high mobility group) box
  • ( PF04212 ) MIT domain
  • ( PF08946 ) Osmosensory transporter coiled coil
  • ( TIGR00183 ) isocitrate dehydrogenase, NADP-dependent

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_05193.1 5.99779123503299e-175
Description: HMG box family protein (631 aa)
SGD YKL032C 0.000005998506718272351
Description: IXR1 Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b
Oxytricha Contig4658.0.g2 0.000009999254677478949
Description: GCC2 and GCC3
DictyBase DDB_G0282427 1
Description: DDB_G0282427 on chromosome: 3 position 5755702 to 5758268

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:31932604: Nabeel-Shah S, Ashraf K, Saettone A, Garg J, Derynck J, Lambert JP, Pearlman RE, Fillingham J (2020) Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila. Scientific reports 10(1):168

Sequences 

>TTHERM_00641210(coding)
ATGGCATTTAGTTCAAAGACTTCTTACTAAATTTATTACGAAGAGCAGTGTAAAATCTAC
AAGTAAAAAGGTATTACAGGAAATGAAGCTGCTAAGCTTATAGGAAAATAATGGAGCAGC
CTCTCTCCTTAGGAGAAAAAACCATATGATGATAAAAAGAAGGAGTATGAGTAATAAGTA
TTAAGAGAATAAAAAGTCATGAAGGACTTTTAAAAGAAGAGCTAACAAGATAATCAACAA
GCTAACAATAAATCTAATGCTACTTAGAAAAATGTAAATGATGAAAAACAAAACAGCTAA
TAAAAACAAGGAAATATTAAGAAATTTATGAAGGAAGATCTTCAAAAAGAAAAGTAAGAT
ATTCACAAAAAAGTTATTATCAAAAAGGTTGATAGCTCAGGAAAAGTATTATCATCCAAC
TCTTAGTAGCCCTAAACTTAAAGTCAGTAATCAGAAAAGTAAAAACCTTCGAATTAGCAG
CAAAAAAATACTCAAGCTAATAAAGCATCTGAGTAAAAGTAATAGAATAATAATAATAAT
AATCAAAACTCTCAAGAAAAGAAGGTCTAAAAACCAAAAGAGTAATAGCAATACTTTTAG
ATGAACAGTGAATAGGAAAATCTTAGAAAATCTAATCACTAAATTTATATTGATTTCTAC
AAAGAGAGACTTGCTTTTTACTAAAAACGCTTCCCATAGAGAACAGCAAAAGAATTAACT
CAAGTAGTTAAAGAAGAGTGGGACTGCGTTAAACTGCAAAGTAAAATTCAATAAAAAAAT
TAAAAAAAAGAAGTAAAATAAAACAAGGAAGTTTAAACAGTTTAAAAAGAAGGGAAAAAA
ATAGTTGAAATTGATGGTAAACAATTAGAAGTCCCTAAAAAACCTCTTTCAGGATATCTC
AGATACTATTAAGAAGTTTAGCATAAGCTTAAATTAAAAAATCCAGATTAAGCTTAAAAT
GAAATTGCTAAATTAGCTAGTGATTAATGGAAGGCTTTGTCAAAAGAATAATAAGAATAA
TACAATAGTTAATATCGTAAAGAATAATTGGAATATACTAATAAAATAAATGAAATCAAA
TAAAAATATAATATCGTACCTGTTGGAACAAGCTAAAAGAAAACTAAAAAGAACTCTAAA
AACTTTATTATCGTAGATAACTAAAAAGTTTTCTATCCTTTGAGACTTGGAGGCTATTTT
GTATATTAAAGAGTTGCCAGGGAACAATTAAGTAAATAAAATCATAATCGTGACTCGAGA
GAGATTTCTTCAATTATAGGATAAACATGGAAGTAGATGTCTGAGCTAGAAAAATAATAC
TATGAAAATTAAAGTGAAGTTGAATACTAGGAGCAAAAGAAAAACTTTATAGAAAAATAT
GGAGAGTTCCCTGAATAAGAAGTTAAAATAAAGCAAAAACCTAGTTAAAAAATTGAGTAA
AGCCAGTCTAAAAAGATTAATCAAAAAAGAAAAGCTCCTTCTTAAAAAGCAGAACCAGAA
ATTTCCAGTGAAGAAAAGGAAGAATAAATTAAGAAAAAGTATGAAAGAAAAATGAGAATA
AATTATGATGATGTTGAAAGTGAAATTGAAGATATTTACAGTGACATAGAAAAGGATTAA
AAGAAAAAATAAACTAGAGTTTAATACCAAGACGAAACAGATCAAGAAGAAGAAGAAGAT
GAAATTTAAGATCTTAGAAAATAGAATTTAAACAATAGAACATAGTAAAAAACAGGAAAA
GAAGAAAATTTTGATGAAATAGAAAAATAATCTACAAAAAATAAAAAAATTAAAACTGAA
AAAAGAAATTCTTCTGTGCCTAAACCAGGTTCTGCTTCTAAATAAACGAATCGTTTGTTT
GAAATGTTGAAGCAACCTATATAAGCACCAGAAGGTTTTGATTTTTAATTTGAATGA


>TTHERM_00641210(gene)
ATGGCATTTAGTTCAAAGACTTCTTACTAAATTTATTACGAAGAGCAGTGTAAAATCTAC
AAGTAAAAAGGTATTACAGGAAATGAAGCTGCTAAGCTTATAGGAAAATAATGGAGCAGC
CTCTCTCCTTAGGAGAAAAAACCATATGATGATAAAAAGAAGGAGTATGAGTAATAAGTA
TTAAGAGAATAAAAAGTCATGAAGGACTTTTAAAAGAAGAGCTAACAAGATAATCAACAA
GCTAACAATAAATCTAATGCTACTTAGAAAAATGTAAATGATGAAAAACAAAACAGCTAA
TAAAAACAAGGAAATATTAAGAAATTTATGAAGGAAGATCTTCAAAAAGAAAAGTAAGAT
ATTCACAAAAAAGTTATTATCAAAAAGGTTGATAGCTCAGGAAAAGTATTATCATCCAAC
TCTTAGTAGCCCTAAACTTAAAGTCAGTAATCAGAAAAGTAAAAACCTTCGAATTAGCAG
CAAAAAAATACTCAAGCTAATAAAGCATCTGAGTAAAAGTAATAGAATAATAATAATAAT
AATCAAAACTCTCAAGAAAAGAAGGTCTAAAAACCAAAAGAGTAATAGCAATACTTTTAG
ATGAACAGTGAATAGGAAAATCTTAGAAAATCTAATCACTAAATTTATATTGATTTCTAC
AAAGAGAGACTTGCTTTTTACTAAAAACGCTTCCCATAGAGAACAGCAAAAGAATTAACT
CAAGTAGTTAAAGAAGAGTGGGACTGCGTTAAACTGCAAAGTAAAATTCAATAAAAAAAT
TAAAAAAAAGAAGTAAAATAAAACAAGGAAGTTTAAACAGTTTAAAAAGAAGGGAAAAAA
ATAGTTGAAATTGATGGTAAACAATTAGAAGTCCCTAAAAAACCTCTTTCAGGATATCTC
AGATACTATTAAGAAGTTTAGCATAAGCTTAAATTAAAAAATCCAGATTAAGCTTAAAAT
GAAATTGCTAAATTAGCTAGTGATTAATGGAAGGCTTTGTCAAAAGAATAATAAGAATAA
TACAATAGTTAATATCGTAAAGAATAATTGGAATATACTAATAAAATAAATGAAATCAAA
TAAAAATATAATATCGTACCTGTTGGAACAAGCTAAAAGAAAACTAAAAAGAACTCTAAA
AACTTTATTATCGTAGATAACTAAAAAGTTTTCTATCCTTTGAGACTTGGAGGCTATTTT
GTATATTAAAGAGTTGCCAGGGAACAATTAAGTAAATAAAATCATAATCGTGACTCGAGA
GAGATTTCTTCAATTATAGGATAAACATGGAAGTAGATGTCTGAGCTAGAAAAATAATAC
TATGAAAATTAAAGTGAAGTTGAATACTAGGAGCAAAAGAAAAACTTTATAGAAAAATAT
GGAGAGTTCCCTGAATAAGAAGTTAAAATAAAGCAAAAACCTAGTTAAAAAATTGAGTAA
AGCCAGTCTAAAAAGATTAATCAAAAAAGAAAAGCTCCTTCTTAAAAAGCAGAACCAGAA
ATTTCCAGTGAAGAAAAGGAAGAATAAATTAAGAAAAAGTATGAAAGAAAAATGAGAATA
AATTATGATGATGTTGAAAGTGAAATTGAAGATATTTACAGTGACATAGAAAAGGATTAA
AAGAAAAAATAAACTAGAGTTTAATACCAAGACGAAACAGATCAAGAAGAAGAAGAAGAT
GAAATTTAAGATCTTAGAAAATAGAATTTAAACAATAGAACATAGTAAAAAACAGGAAAA
GAAGAAAATTTTGATGAAATAGAAAAATAATCTACAAAAAATAAAAAAATTAAAACTGAA
AAAAGAAATTCTTCTGTGCCTAAACCAGGTTCTGCTTCTAAATAAACGAATCGTTTGTTT
GAAATGTTGAAGCAACCTATATAAGCACCAGAAGGTTTTGATTTTTAATTTGAATGA


>TTHERM_00641210(protein)
MAFSSKTSYQIYYEEQCKIYKQKGITGNEAAKLIGKQWSSLSPQEKKPYDDKKKEYEQQV
LREQKVMKDFQKKSQQDNQQANNKSNATQKNVNDEKQNSQQKQGNIKKFMKEDLQKEKQD
IHKKVIIKKVDSSGKVLSSNSQQPQTQSQQSEKQKPSNQQQKNTQANKASEQKQQNNNNN
NQNSQEKKVQKPKEQQQYFQMNSEQENLRKSNHQIYIDFYKERLAFYQKRFPQRTAKELT
QVVKEEWDCVKLQSKIQQKNQKKEVKQNKEVQTVQKEGKKIVEIDGKQLEVPKKPLSGYL
RYYQEVQHKLKLKNPDQAQNEIAKLASDQWKALSKEQQEQYNSQYRKEQLEYTNKINEIK
QKYNIVPVGTSQKKTKKNSKNFIIVDNQKVFYPLRLGGYFVYQRVAREQLSKQNHNRDSR
EISSIIGQTWKQMSELEKQYYENQSEVEYQEQKKNFIEKYGEFPEQEVKIKQKPSQKIEQ
SQSKKINQKRKAPSQKAEPEISSEEKEEQIKKKYERKMRINYDDVESEIEDIYSDIEKDQ
KKKQTRVQYQDETDQEEEEDEIQDLRKQNLNNRTQQKTGKEENFDEIEKQSTKNKKIKTE
KRNSSVPKPGSASKQTNRLFEMLKQPIQAPEGFDFQFE