Identifiers and Description

Gene Model Identifier

TTHERM_00670340

Standard Name

LRS1 ( leucyl-tRNA synthetase 1)

Aliases

PreTt01058 | 100.m00119 | 3731.m00029

Description

LRS1 cytoplasmic leucyl-tRNA synthetase; leucyl-tRNA synthetase family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IEA) | GO:0005737

Molecular Function

• aminoacyl-tRNA ligase activity (IEA) | GO:0004812
• ATP binding (IEA) | GO:0005524
• nucleotide binding (IEA) | GO:0000166

Biological Process

• translation (IEA) | GO:0006412
• tRNA aminoacylation for protein translation (IEA) | GO:0006418

Domains

• ( PF00133 ) tRNA synthetases class I (I,
• ( PF08264 ) Anticodon-binding domain
• ( PF09334 ) tRNA synthetases class I (M)
• ( TIGR00392 ) isoleucine--tRNA ligase
• ( TIGR00395 ) leucyl-tRNA synthetase
• ( TIGR00396 ) leucyl-tRNA synthetase
• ( TIGR00398 ) methionyl-tRNA synthetase
• ( TIGR00422 ) valyl-tRNA synthetase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_22485	0
	Description: None
WormBase	WBGene00003073	9.997093137033517e-262
	Description: locus:lars-1 Leucine--tRNA ligase status:Confirmed UniProt:Q09996 protein_id:CAA85280.1
Tetrahymena borealis	EI9_16448.1	9.997093137033517e-262
	Description: leucyl-tRNA synthetase (1078 aa)
DictyBase	DDB_G0285451	9.997093137033517e-262
	Description: leuS on chromosome: 4 position 3240792 to 3244287
Oxytricha	Contig579.1.g57	9.997093137033517e-262
	Description: tRNA synthetases class I (I, L, M and V)
SGD	YPL160W	9.997093137033517e-262
	Description: CDC60 Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00670340(coding)
ATGTGTATATTTGGAAAATTATATTTCAAACTATAAAAATTAAACAGTTCATAATTTAAG
ATATTTTTGCAAAAAATTAGATAAAGTTTTAGTACACTAAATTAATAAATGGAAGATAAA
CCTAAATAAAACTTCGCAAGAAGAGATCGTTTAGTCGAACTTGAAAAGTAAGCCTAAAAG
AAATGGGAAGATGAAAAGACTTATGAATCTAACCCTAATCCTGGATAAAAGAAGTACTTG
GTTACTTTCCCTTATCCTTATTTGAATGGTAGATTGCATTTGGGACACAGCTATACCATG
ACTAAAGTTGATTTCATTGCTCGTTATAAGCGTCTTAATGGATTTAATGTCGTTTTCCCC
TTCGGTTTCCATTGCACCGGTTAGCCTATTTCTGCTGCTGCCACCAAGCTTAGAAGAGAA
ATAGAAGAATATGGTCTTCCTCCAGTTTTCCCCGAAGAAAAGAAGGAGCAAAGACAATGG
AATATCCTCAAGAAGATGGGTATCCCTGATGAAGACATTCCTAAATTCTAAGAAGGTAAA
TTCTGGTGTGGTTATTTCCATCCTTTTGCCACTTAAGATTTGAAGTCTTTTGGTGTTGCT
GTTGATCACAGAAGATCCTTTATTACTACTGATGTTAATCCTTACTATGACTCATTCATT
CAATGGTAGTTCACTCTTTTGAAAGAAAGAAACTATATTCGTTATGGTAAGAGACCTTCC
ATTTTCTCCGTCGCAGATAATCAAATTTGTGCTGATCACGACAGAGCTTAAGAATCTGAA
GGTATTGGTCCATAAGAATACACTCTTATTAAGTTGAAGGTTCTCGAATTCCACGGAGCT
TTGAAGGCTCTTGAAGGCAGAAACGTTTACTTGGCTGCTGCTACTTTGAGACCTGAAACT
ATGTATGGTTAAACTAACTGTTACATTCTTCCTGATGGTGTTTATGGTGCTTTTGAAGTC
ACTAATGATGAAGTCTTTATTGTTGCTGAAAGAGCTGCTAAGAATATGGCTTACTAAGAT
TTGACTAAAGAATATGGTAAATATGTTAAAATTATGGATATTAAGGGTACTGATTTGTTG
GGCATTCCTTTGAAGGCTCCTCTTTCCACCTACGAAAAGGTTTATGCTCTCCCTATGCTT
ACTATTTCTATGGAAAAGGGTACTGGTGTTGTTACTTCAGTTCCTTCTGACTCTCCTGAT
GACTATGCTGCTCTTAGAGATTTGAAGAACAAGGCTCCTCTTAGAGAAAAGTATGGAATC
AAAGAAGAACACGTATTGCCATTTGAACCTGTTCCTATCATTAACATTCCTGAATTGGGA
GATCTTGCTGCTATTGTTGCTTGTGAAAAGCATAAAGTAGCCTCTCAAAATGATAAAGAA
AATCTTAAAAATGCTAAGGATGAGTGTTACTTGAAGGGTTTCTATGATGGTGTTATGAAA
GTTGGTAAGTACGCAGGTGTTAAGGTTTAAGACGCTAAGAATTTGGTAAAGAATGATATG
TTAGCCTCTGGTGAAGCCGCTAAGTACTGGGAACCTGAAGGAAAGGTCATTTCCAGATCT
GGTGATGAATGTATTGTTGCCCTCATGGACTAATGGTATCTTGCTTACGATGAAGAAGAA
TGGAAGAAACCAGTTAGAGATCATGTTAAAAATGTATTCAATTGTTACAACGATATCGTT
CACAAGAGCTTCATTGCTACTGTTGAATGGTTGTAACAATGGGGTTGTTCTCGTTCTTTT
GGTCTTGGTAGTTACCTTCCTTTTGATAAGAACTATCTCGTTGAATCTCTTTCTGATTCC
ACCATCTACATGGCTTATTACACTGTTGTTCACTTGTTACAAGGAAACGTTGTTGGTTCT
CAAGCAGGTCCTCTAGGAATTAACCCTGATTAGATGAACAGAGAATTCTGGGACTACGTA
TTCTTGAATGCTCCTTATTCTGATAAGATTAAAGTTGAAGAAGAAAAGATTAAACAACTT
AGAGAATCCTTTAGATATTGGTATCCTCTTGATTTGAGAGGATCTGCTAAGGATTTGGTT
AAGAACCACTTGACCATGTGTATTTTCAACCATGCTGCCATTTGGAAAGATGAACCTAAC
ATGTGGCCTCGTTCATTCTTTGTTAATGGATATATGCTTGTTGATGGTGAAAAAATGTCC
AAGTAAAAGGGTAACTTCTTTACATTGAAGGATATCGTCTCAATGTACGGTGCTGATGCT
TGCCGTTTTGCTTTATCTGAAGCCGGTGACACCCAAGATGATGCTAACTTCGAAAAGCAA
GTTGCTGATAACTCAATTCTTAAAATTTCTACTTTGGAAATGTGGTTAAAGGAATACATT
GCTAACCATCAAAATAGTAGAACTGAAAGCCCCAATGAAAATATTACTTTCTTCGATAAG
GTCTTCGAAAATTAAATTAAGAATCTCTATGTCAACTGTATAAAATCTTATGAAGATATG
CGTTTCAGAGATGTTGCTAAATTCGGCTTCCACGAATTCGGTACAATCAAAGAAGAATAT
CTTATCAATTGTGGTACTTTTGGACCTCGTAAGGACCTTATCCTTACCTGGATTTAATAT
CAACTTTTGATTATGTATCCCATCATTCCTCACTTCTGTGAAATGGCTTGGGTTATTTAC
TTCCTTCCTCTTGTTAACAACAGTGCATAATATCCTGCTACTCTTTCCCAAGCAACTTTA
CCTGAAGTTAACGCTGCCAGTATTGATGCCATCACTATCCGTGCCTACAATTGCTTATAA
TCTTTCTTGAGAAATCTCCGTGTTACTTATAAGAAATCTACTCAAACTAAGAAGGGTGCC
AAGGATGTCACTTTCACAAAGGTTACTGTTATTTATGCTCCTAAGTATCCTGATTGGTAA
CAATATGTCTTAAATATCTTGAATGAACAACTCGAAGGAAACAAGATCAAGGATGCTTGG
AAGGTCATCCTTAAGGAGAAGATTACTGATAAGAATCTCTTAAGTAAATCATTGCAATTT
GCATCTTTTGTTACCAAGGAATTCGAATAAGCAGGAAAAGAAGTTCTTGAATCTACTCTT
CCTTTCAACGAAATTTAACTCTTATAAGACAATAAGCACTTGATCCAAAAGGAACTCAAA
ATCGAAGATGTTAATTTCATTTCTGTAGATCAAGCTGAAAGTCTTAAGGACAAGACTTAC
GCACAAGCTCTTCAATCTTGTGTTCCAGGCAAGGCTCAAGTCGTTTTTGCTTGA

>TTHERM_00670340(gene)
ATGTGTATATTTGGAAAATTATATTTCAAACTATAAAAATTAAACAGTTCATAATTTAAG
ATATTTTTGCAAAAAATTAGATAAAGTTTTAGTACACTAAATTAATAAATGGAAGATAAA
CCTAAATAAAACTTCGCAAGAAGAGATCGTTTAGTCGAACTTGAAAAGTAAGCCTAAAAG
AAATGGGAAGATGAAAAGACTTATGAATCTAACCCTAATCCTGGATAAAAGAAGTACTTG
GTTACTTTCCCTTATCCTTATTTGAATGGTAGATTGCATTTGGGACACAGCTATACCATG
ACTAAAGTTGATTTCATTGCTCGTTATAAGCGTCTTAATGGATTTAATGTCGTTTTCCCC
TTCGGTTTCCATTGCACCGGTTAGCCTATTTCTGCTGCTGCCACCAAGCTTAGAAGAGAA
ATAGAAGAATATGGTCTTCCTCCAGTTTTCCCCGAAGAAAAGAAGGAGCAAAGACAATGG
AATATCCTCAAGAAGATGGGTATCCCTGATGAAGTAATTTTTTAATTTTCCTAATATAAA
AATAAGCAAAAAACTAGCAAATTTATGCTTTCAAAGATAGATCTTAACTAAGCATTGTTG
AATAGCTATCTTCCCATGAAAAAAGCAAAATAAATAAATCCTTCGCTAAAATATTTCAAT
AAATCAGAAGAAAAGCACTAACAAGCAGATACATTATTATTGACTGATTAGGCTGAATTT
CACTAAATACATTAAAATGAAATTTAATTAATTATTAACTAATTCAATTTTTAAAACAGG
ACATTCCTAAATTCTAAGAAGGTAAATTCTGGTGTGGTTATTTCCATCCTTTTGCCACTT
AAGATTTGAAGTCTTTTGGTGTTGCTGTTGATCACAGAAGATCCTTTATTACTACTGATG
TTAATCCTTACTATGACTCATTCATTCAATGGTAGTTCACTCTTTTGAAAGAAAGAAACT
ATATTCGTTATGGTAAGAGACCTTCCATTTTCTCCGTCGCAGATAATCAAATTTGTGCTG
ATCACGACAGAGCTTAAGAATCTGAAGGTATTGGTCCATAAGAATACACTCTTATTAAGT
TGAAGGTAAAAAAATAGAATCTTATCTAAAATTTTTTAATCTAAAATAAATCTCTTTTTT
TAAAAAGATATCTTATTATATCAATATAAACATTAAAACCTATTCAATACATTTTATCAA
TTAATTACCACAACATAATTCGTCCACTTATAGAATACCCCTTTAGCAAAACTCAATAAA
ATATTTTTTTTTTTCATAATAGGTTCTCGAATTCCACGGAGCTTTGAAGGCTCTTGAAGG
CAGAAACGTTTACTTGGCTGCTGCTACTTTGAGACCTGAAACTATGTATGGTTAAACTAA
CTGTTACATTCTTCCTGATGGTGTTTATGGTGCTTTTGAAGTCACTAATGATGAAGTATA
TATTTTATTAATATTGTTTTTTTACTTATCTATCAATCTTTGGTTAATTATTTAGCCAAA
ATTTATAATCATATTTATGATAATTTATCCTTATTTTTAAGTGATTTAAATAATGAAATG
TATTTAATAGGTCTTTATTGTTGCTGAAAGAGCTGCTAAGAATATGGCTTACTAAGATTT
GACTAAAGAATATGGTAAATATGTTAAAATTATGGATATTAAGGGTACTGATTTGTTGGG
CATTCCTTTGAAGGCTCCTCTTTCCACCTACGAAAAGGTTTATGCTCTCCCTATGCTTAC
TATTTCTATGGAAAAGGGTACTGGTGTTGTTACTTCAGTTCCTTCTGACTCTCCTGATGA
CTATGCTGCTCTTAGAGATTTGAAGAACAAGGCTCCTCTTAGAGAAAAGTATGGAATCAA
AGAAGAACACGTATTGCCATTTGAACCTGTTCCTATCATTAACATTCCTGAATTGGGAGA
TCTTGCTGCTATTGTTGCTTGTGAAAAGCATAAAGTAGCCTCTCAAAATGATAAAGAAAA
TCTTAAAAATGCTAAGGATGAGTGTTACTTGAAGGGTTTCTATGATGGTGTTATGAAAGT
TGGTAAGTACGCAGGTGTTAAGGTTTAAGACGCTAAGAATTTGGTAAAGAATGATATGTT
AGCCTCTGGTGAAGCCGCTAAGTACTGGGAACCTGAAGGAAAGGTCATTTCCAGATCTGG
TGATGAATGTATTGTTGCCCTCATGGACTAATGGTATCTTGCTTACGATGAAGAAGAATG
GAAGAAACCAGTTAGAGATCATGTTAAAAATGTATTCAATTGTTACAACGATATCGTTCA
CAAGAGCTTCATTGCTACTGTTGAATGGTTGTAACAATGGGGTTGTTCTCGTTCTTTTGG
TCTTGGTAGTTACCTTCCTTTTGATAAGAACTATCTCGTTGAATCTCTTTCTGATTCCAC
CATCTACATGGCTTATTACACTGTTGTTCACTTGTTACAAGGTATTTATTTATTTATTTT
TTTCATTTTTTTCATTAAATTTATTATTTTTAAAACTAAATTCATTATTTTTATTCAAAA
GGAAACGTTGTTGGTTCTCAAGCAGGTCCTCTAGGAATTAACCCTGATTAGATGAACAGA
GAATTCTGGGACTACGTATTCTTGAATGCTCCTTATTCTGATAAGATTAAAGTTGAAGAA
GAAAAGATTAAACAACTTAGAGAATCCTTTAGATATTGGTATCCTCTTGATTTGAGAGGA
TCTGCTAAGGATTTGGTTAAGAACCACTTGACCATGTGTATTTTCAACCATGCTGCCATT
TGGAAAGATGAACCTAACATGTGGCCTCGTTCATTCTTTGTTAATGGGTAAATAATTATT
TTGCTTTAATTTTTTTATTTCCTCTATTTTCATAAATTAATTGATGAACATTTGCTTAAT
CATAATAATAGATATATGCTTGTTGATGGTGAAAAAATGTCCAAGTAAAAGGGTAACTTC
TTTACATTGAAGGATATCGTCTCAATGTACGGTGCTGATGCTTGCCGTTTTGCTTTATCT
GAAGCCGGTGACACCCAAGATGATGCTAACTTCGAAAAGCAAGTTGCTGATAACTCAATT
CTTAAAATTTCTACTTTGGAAATGTGGTTAAAGGAATACATTGCTAACCATCAAAATAGT
AGAACTGAAAGCCCCAATGAAAATATTACTTTCTTCGATAAGGTCTTCGAAAATTAAATT
AAGAATCTCTATGTCAACTGTATAAAATCTTATGAAGATATGCGTTTCAGAGATGTTGCT
AAATTCGGCTTCCACGAATTCGGTACAATCAAAGAAGAATATCTTATCAATTGTGGTACT
TTTGGACCTCGTAAGGACCTTATCCTTACCTGGATTTAATATCAACTTTTGATTATGTAT
CCCATCATTCCTCACTTCTGTGAAATGGCTTGGGTTATTTACTTCCTTCCTCTTGTTAAC
AACAGTGCATAATATCCTGCTACTCTTTCCCAAGCAACTTTACCTGAAGTTAACGCTGCC
AGTATTGATGCCATCACTATCCGTGCCTACAATTGCTTATAATCTTTCTTGAGAAATCTC
CGTGTTACTTATAAGAAATCTACTCAAACTAAGAAGGGTGCCAAGGATGTCACTTTCACA
AAGGTTACTGTTATTTATGCTCCTAAGTATCCTGATTGGTAACAATATGTAACATATTTT
TAAAAATATTTTCAAAAAGTAGAGTTAAATATTTTATATTTATTCATTAAAAGGTCTTAA
ATATCTTGAATGAACAACTCGAAGGAAACAAGATCAAGGATGCTTGGAAGGTCATCCTTA
AGGAGAAGATTACTGATAAGAATCTCTTAAGTAAATCATTGCAATTTGCATCTTTTGTTA
CCAAGGAATTCGAATAAGCAGGAAAAGAAGTTCTTGAATCTACTCTTCCTTTCAACGAAA
TTTAACTCTTATAAGACAATAAGCACTTGATCCAAAAGGAACTCAAAATCGAAGATGTTA
ATGTAATTAAATCAATAATGAGTAGCATAAATTAAATTATTACTTTTAATTAAAATAGTT
CATTTCTGTAGATCAAGCTGAAAGTCTTAAGGACAAGACTTACGCACAAGCTCTTCAATC
TTGTGTTCCAGGCAAGGCTCAAGTCGTTTTTGCTTGA

>TTHERM_00670340(protein)
MCIFGKLYFKLQKLNSSQFKIFLQKIRQSFSTLNQQMEDKPKQNFARRDRLVELEKQAQK
KWEDEKTYESNPNPGQKKYLVTFPYPYLNGRLHLGHSYTMTKVDFIARYKRLNGFNVVFP
FGFHCTGQPISAAATKLRREIEEYGLPPVFPEEKKEQRQWNILKKMGIPDEDIPKFQEGK
FWCGYFHPFATQDLKSFGVAVDHRRSFITTDVNPYYDSFIQWQFTLLKERNYIRYGKRPS
IFSVADNQICADHDRAQESEGIGPQEYTLIKLKVLEFHGALKALEGRNVYLAAATLRPET
MYGQTNCYILPDGVYGAFEVTNDEVFIVAERAAKNMAYQDLTKEYGKYVKIMDIKGTDLL
GIPLKAPLSTYEKVYALPMLTISMEKGTGVVTSVPSDSPDDYAALRDLKNKAPLREKYGI
KEEHVLPFEPVPIINIPELGDLAAIVACEKHKVASQNDKENLKNAKDECYLKGFYDGVMK
VGKYAGVKVQDAKNLVKNDMLASGEAAKYWEPEGKVISRSGDECIVALMDQWYLAYDEEE
WKKPVRDHVKNVFNCYNDIVHKSFIATVEWLQQWGCSRSFGLGSYLPFDKNYLVESLSDS
TIYMAYYTVVHLLQGNVVGSQAGPLGINPDQMNREFWDYVFLNAPYSDKIKVEEEKIKQL
RESFRYWYPLDLRGSAKDLVKNHLTMCIFNHAAIWKDEPNMWPRSFFVNGYMLVDGEKMS
KQKGNFFTLKDIVSMYGADACRFALSEAGDTQDDANFEKQVADNSILKISTLEMWLKEYI
ANHQNSRTESPNENITFFDKVFENQIKNLYVNCIKSYEDMRFRDVAKFGFHEFGTIKEEY
LINCGTFGPRKDLILTWIQYQLLIMYPIIPHFCEMAWVIYFLPLVNNSAQYPATLSQATL
PEVNAASIDAITIRAYNCLQSFLRNLRVTYKKSTQTKKGAKDVTFTKVTVIYAPKYPDWQ
QYVLNILNEQLEGNKIKDAWKVILKEKITDKNLLSKSLQFASFVTKEFEQAGKEVLESTL
PFNEIQLLQDNKHLIQKELKIEDVNFISVDQAESLKDKTYAQALQSCVPGKAQVVFA