Identifiers and Description

Gene Model Identifier

TTHERM_00681750

Standard Name

PCP1 (PARP Correlated Protein 1)

Aliases

PreTt16112 | 103.m00103 | 3734.m00016

Description

Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger family protein putative. Vertebrate PARPs contain PADR and zinc finger (zf)–PARP domains. None of the Tetrahymena putative PARPs carry these domains. Instead, Tetrahymena has at least six additional proteins carrying PADR1 and zf–PARP domains(Kanwal Ashraf et al., 2019)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• macronucleus (IDA) | GO:0031039
• micronucleus (IDA) | GO:0031040

Molecular Function

• DNA binding (IEA) | GO:0003677
• zinc ion binding (IEA) | GO:0008270

Biological Process

• DNA replication (IDA) | GO:0006260

Domains

• ( PF00645 ) Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger
• ( PF08063 ) PADR1 (NUC008) domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_14722.1	6.0023901016598e-137
	Description: poly polymerase and DNA-Ligase Zn-finger region family protein (324 aa)
Stentor Coeruleus	SteCoe_10542	0.0000000000006914400106940203
	Description: None
DictyBase	DDB_G0291872	0.00006000996057121373
	Description: DDB_G0291872 on chromosome: 6 position 855161 to 857960

General Information

No Data fetched for General Information

Associated Literature

1. Ref:30796450: Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ):

Sequences

>TTHERM_00681750(coding)
ATGAGCGCGAAAGAATTAAAGTTTGATTATGCAAGCTCAAGTAGAGCTGGATGCAAAGGA
TGTAAAATGAAAATTTAAAAAAATGAGCTTAGAATAGGATTAGAAACTCTCTTTTAAGGT
GAGCATACAACGACTTCATGGAGACATTTAGAATGCTTTAGTCTTGGTAGAAAATATAAA
GATATTGATCCTAAAGAAATTGAAGGTTATTATGATTTAAAAAAGGAAGATAAAGCTAGG
GTAATAGATTACTTTGAAGGAGGTGGTCAAAAAAAATCTGTAGTTGATAAACTGATATCT
ACAATAACAGATTCAGAAAAGAAAAAAAAATAAGACGATGATGGTGATGACAATCAAGTT
TATGATTACGATGCTGAATAATAGAAGAAGAAAAATTAATAGTAAAAAGAAAAGAAAAAA
ATTACTAAACCTAAATTAAAAAGAAAGCTATCAAGTTCTTCAGAAGAGGAAGATGATTCG
TCTGATTCAGAAGATGATTTTGATGACTCAGAGACTGATAACTCAGGTAGTGATAGTGAT
TATGAAAAAGAAAAAGCTATCTAAAGAAAAAATCAACATAAAAAATTAGCAAGAAAAAAA
AAATCAAAAGGAAAAAGTAAAAGCAGCACTGAAATAAATATTGGTTACACTCCTGAATAG
TTACTTAAATTCAAAGAAAATTTAAAATTATATGAAAAAAAAACTGCAGAATACTTAAAG
GCTTTATTAGGAATTAACAATTAGCCTAAAACTGGTACAAAGGATGAATTAGTTTTGAAA
TGCGCAGATGGTAAAACACTTGGACAAATTCCAATATGTTCTGAGTGTGGTGGAGGGAAA
TTAAGGTATGATATATAAACTGGTATTTACAAATGTCCTGGATATATGGATGATGATGTT
TTTTAGCATTGTGGTAAAAAATTTACAAATGAATAAATTGTCAGATTACCTTGGATTGAT
GATATTATTTGA

>TTHERM_00681750(gene)
ATGAGCGCGAAAGAATTAAAGTTTGATTATGCAAGCTCAAGTAGAGCTGGATGCAAAGGA
TGTAAAATGAAAATTTAAAAAAATGAGCTTAGAATAGGATTAGAAACTCTCTTTTAAGGT
GAGCATACAACGACTTCATGGAGACATTTAGAATGCTTTAGTCTTGGTAGAAAATATAAA
GATATTGATCCTAAAGAAATTGAAGGTTATTATGATTTAAAAAAGGAAGATAAAGCTAGG
GTAATAGATTACTTTGAAGGAGGTGGTCAAAAAAAATCTGTAGTTGATAAACTGATATCT
ACAATAACAGATTCAGAAAAGAAAAAAAAATAAGACGATGATGGTGATGACAATCAAGTT
TATGATTACGATGCTGAATAATAGAAGAAGAAAAATTAATAGTAAAAAGAAAAGAAAAAA
ATTACTAAACCTAAATTAAAAAGAAAGCTATCAAGTTCTTCAGAAGAGGAAGATGATTCG
TCTGATTCAGAAGATGATTTTGATGACTCAGAGACTGATAACTCAGGTAGTGATAGTGAT
TATGAAAAAGAAAAAGCTATCTAAAGAAAAAATCAACATAAAAAATTAGCAAGAAAAAAA
AAATCAAAAGGAAAAAGTAAAAGCAGCACTGAAATAAATATTGGTTACACTCCTGAATAG
TTACTTAAATTCAAAGAAAATTTAAAATTATATGAAAAAAAAACTGCAGAATACTTAAAG
GCTTTATTAGGAATTAACAATTAGCCTAAAACTGGTACAAAGGATGAATTAGTTTTGAAA
TGCGCAGATGGTAAAACACTTGGACAAATTCCAATATGTTCTGAGTGTGGTGGAGGGAAA
TTAAGGTATGATATATAAACTGGTATTTACAAATGTCCTGGATATATGGATGATGATGTT
TTTTAGCATTGTGGTAAAAAATTTACAAATGAATAAATTGTCAGATTACCTTGGATTGAT
GATATTATTTGA

>TTHERM_00681750(protein)
MSAKELKFDYASSSRAGCKGCKMKIQKNELRIGLETLFQGEHTTTSWRHLECFSLGRKYK
DIDPKEIEGYYDLKKEDKARVIDYFEGGGQKKSVVDKLISTITDSEKKKKQDDDGDDNQV
YDYDAEQQKKKNQQQKEKKKITKPKLKRKLSSSSEEEDDSSDSEDDFDDSETDNSGSDSD
YEKEKAIQRKNQHKKLARKKKSKGKSKSSTEINIGYTPEQLLKFKENLKLYEKKTAEYLK
ALLGINNQPKTGTKDELVLKCADGKTLGQIPICSECGGGKLRYDIQTGIYKCPGYMDDDV
FQHCGKKFTNEQIVRLPWIDDII