Identifiers and Description

Gene Model Identifier

TTHERM_00837850

Standard Name

TTLL4D (Tubulin Tyrosine Ligase-Like )

Aliases

PreTt17798 | 146.m00099 | 3743.m00030

Description

TTLL4D tubulin-tyrosine ligase family protein; Related to tubulin polyglutamylase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• acid-amino acid ligase activity (ISS) | GO:0016881
• tubulin-tyrosine ligase activity (IEA) | GO:0004835

Biological Process

• cellular protein modification process (IEA) | GO:0006464
• protein polyglutamylation (ISS) | GO:0018095

Domains

• ( PF03133 ) Tubulin-tyrosine ligase family
• ( PF07453 ) NUMOD1 domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_19551.1	9.997093137033517e-262
	Description: tubulin-tyrosine ligase (683 aa)
Oxytricha	Contig16959.0.g38	2.9988601762256104e-132
	Description: Tubulin-tyrosine ligase family
WormBase	WBGene00008331	3.000809166761476e-75
	Description: locus:ttll-5 status:Partially_confirmed UniProt:O17720 protein_id:CAB02862.3
Stentor Coeruleus	SteCoe_27639	3.917469664450395e-64
	Description: None
DictyBase	DDB_G0281541	3.0000451088882257e-25
	Description: DDB_G0281541 on chromosome: 3 position 4627625 to 4629265
SGD	YBR094W	0.00008003872323201264
	Description: PBY1 Putative tubulin tyrosine ligase associated with P-bodies

General Information

No Data fetched for General Information

Associated Literature

1. Ref:15890843: Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM, Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S, Gaertig J, Eddé B (2005) Tubulin polyglutamylase enzymes are members of the TTL domain protein family. Science (New York, N.Y.) 308(5729):1758-62

Sequences

>TTHERM_00837850(coding)
ATGAATATTAGGTCTCAACGGCTGTAACCTATGCAATATGAATTTTATGATAGTAACTAA
AGATAAGAGTCTGCTTTGAAATAAAATTCATTTTCGAAATTTAACGAAAACAATGATGAA
GATGAATTAGATTCTCTTATTTAATTTTGTAGTTCTTTGAATAAAAATTCAAATAATGTT
GCTAAACTTCCACCTAAATTGATCCCTGTGAATTAAAATATTGTTAGATACTTATAATTT
AAACCTTGGAATGGTGTTTTATAAGATAATGTTTAAGACAGTGGCTATTATTTTAAGTTA
AACAATTGTAATATTAAACTAGTAAGAGGGCTACTAGAAGAAAATGGATTTAGAGAAACC
ATTGACAAAGATTGGACAATTATGTGGGTCGTTGGATCTATAAAATCGGAAATATATCAA
ACCATGATGGCATATTAAAAAGTTAACCACTTTCCTAAGAGTATTGAAATTACTAGGAAA
GATTTGATGAACAGAAATATAAGCAAGATGTAAATAAGATGTGGGTTATCTAACTTTAAT
TTTGTTCCTAAAACCTACATTCTACCATCAGAGTAATCTCTGCTTATAGAAGATTTTGAA
AAGATTAAATCCACAAAGTAATTATTTATTGTTAAACCTTAGAATGGTTCATAGGGAAAG
AATATATTTGTTACTGATAAGCTAAACGATATTCTGAGAGCAAATGTCGGAAGCGGTTTA
GTTGTCAGCCATTATGTAGCGAATCCTCTTTTAATTAACAATTTAAAATTCGATTTGAGA
ATATATGTTGCAATTACTTCTATTCATCCTTTAAGAGTATATATTTATGAAGATGGGCTG
GTTAGGTTTGCAACTTAAGAATATCATGCTGATATTGATCTACTTAAAGATAAGTACGTC
CACTTGACAAACTATAGCATTAACAAAAACAGCAATAATTTTGTTAGTAATAAGGATGCT
TAAGAAGATTTTAAAGGAAGTAAATGGTCACTTGCATCTCTTAAAGATTACTTAAGAGTC
AATGGGATTAATGTGGAGCAACTATTTGATAAAATAGAAGACATGATAGTAAAAACAATC
ATCTCAATTGAGGGATAAATTTTCAGTTCTTTTGAAATGCAAGTTCCATATAGAAATAAT
TGCTTTGAAGTATTAGGTTTTGATGTTTTGATAGATGACACATTAAAACCCTACCTGCTT
GAAGTTAATTTGAATTCTTCTTTAAATACTGATAGTCCTTTAGATTTAAGAATAAAAGGT
GAAATGTTAAGCGATTTATTTACTTTAGTTGGGATAGTTCCCTTAGACTAAAGGTACTCA
ATCGATTAGTCTTTCAACTTTACATTAAATAGTGCAATAAATGAAAAATAATATGCTAAC
ATAGTCAATTCGTTGACATCTAATTGGGAGTAACATAAGAAACAATTAACAAAACTTGAA
AGGGCAGTTTTAAAAGAAACTGAAGACGAGCTCAAAAGATGTAGAAAATTCAAGAGAATT
TATCCAGGTGAAACGTGCTTTAAATATAAAAATTACTTTGAATAAGATAGACCTTTTAAT
ATTTTATTGAGAAATTGGGAAATGGATAAGGCAAAGAAAAATAATATAAATCAAAGTTTA
AACAATCATAAATACAGTGCACCTGTGAGTAGACAAGCAAATCATAGTTCTGCACAAAAA
ACATCACCATCTAACACAAGCTATTACTAAAATACTTCTTTTAATAAAATTGGAGCCTCC
ACTTTAGGATAAAGAAATAGTTCTTTACTTAAATCAGTAAATATAAAAAGAAACTGA

>TTHERM_00837850(gene)
ATGAATATTAGGTCTCAACGGCTGTAACCTATGCAATATGAATTTTATGATAGTAACTAA
AGATAAGAGTCTGCTTTGAAATAAAATTCATTTTCGAAATTTAACGAAAACAATGATGAA
GATGAATTAGATTCTCTTATTTAATTTTGTAGTTCTTTGAATAAAAATTCAAATAATGTT
GCTAAACTTCCACCTAAATTGATCCCTGTGAATTAAAATATTGTTAGATACTTATAATTT
AAACCTTGGAATGGTGTTTTATAAGATAATGTTTAAGACAGTGGCTATTATTTTAAGTTA
AACAATTGTAATATTAAACTAGTAAGAGGGCTACTAGAAGAAAATGGATTTAGAGTATTT
TTTAGCTTTCTTTAAATGGCAATTATTTTAATAAAAACTAAATGATTATTAGGAAACCAT
TGACAAAGATTGGACAATTATGTGGGTCGTTGGATCTATAAAATCGGAAATATATCAAAC
CATGATGGCATATTAAAAAGTAAATATATTTTTTGTTAGTTTTATCAATATATATATTCG
GGGATATTTAAGAAAATCAAATTAGAATTTGAATATTATACTTTAATAAATCAACAAAAA
TTTATAGTTTGAAAAGACAGCATTAAAAACAGCAACAACAATGCAAAATATATATTATTC
AAATAGGTTAACCACTTTCCTAAGAGTATTGAAATTACTAGGAAAGATTTGATGAACAGA
AATATAAGCAAGATGTAAATAAGATGTGGGTTATCTAACTTTAATTTTGTTCCTAAAACC
TACATTCTACCATCAGAGTAATCTCTGCTTATAGAAGATTTTGAAAAGATTAAATCCACA
AAGTAATTATTTATTGTTAAACCTTAGAATGGTTCATAGGGAAAGAATATATTTGTTACT
GATAAGCTAAACGATGTAATAATAATGTATTTTTTTAATTATTTACATTAAATGATTATT
AAAAGATTCTGAGAGCAAATGTCGGAAGCGGTTTAGTTGTCAGCCATTATGTAGCGAATC
CTCTTTTAATTAACAATTTAAAATTCGATTTGAGAATATATGTTGCAATTACTTCTATTC
ATCCTTTAAGAGTATATATTTATGAAGATGGGCTGGTTAGGTTTGCAACTTAAGAATATC
ATGCTGATATTGATCTACTTAAAGATAAGTAATGATAATATTAATTAAAGTAGTTTTAAT
ATTTTGAAAATGTATAAATAAGGTACGTCCACTTGACAAACTATAGCATTAACAAAAACA
GCAATAATTTTGTTAGTAATAAGGTAAATAAATATTGCTTTCATAACAAGCAACTGATTC
AATATAATAAATTATTTAGGATGCTTAAGAAGATTTTAAAGGAAGTAAATGGTCACTTGC
ATCTCTTAAAGATTACTTAAGAGTCAATGGGATTAATGTGGAGCAACTATTTGATAAAAT
AGAAGACATGATAGTAAAAACAATCATCTCAATTGAGGGATAAATTTTCAGTTCTTTTGA
AATGCAAGTTCCATATAGAAATAATTGCTTTGAAGTATTAGGTTTTGATGTTTTGATAGA
TGACACATTAAAACCCTACCTGCTTGAAGTTAATTTGAATTCTTCTTTAAATACTGATAG
TCCTTTAGATTTAAGAATAAAAGGTGAAATGTTAAGCGATTTATTTACTTTAGTTGGGAT
AGTTCCCTTAGACTAAAGGTACTCAATCGATTAGTCTTTCAACTTTACATTAAATAGTGC
AATAAATGAAAAATAATATGCTAACATAGTCAATTCGTTGACATCTAATTGGGAGTAACA
TAAGAAACAATTAACAAAACTTGAAAGGGCAGTTTTAAAAGAAACTGAAGACGAGCTCAA
AAGGTAATCTAAACCACTTATCAAATAAATGAAATTAATTAAAGATAAATATTTTTAATT
ATAGATGTAGAAAATTCAAGAGAATTTATCCAGGTGAAACGTGCTTTAAATATAAAAATT
ACTTTGAATAAGATAGACCTTTTAATATTTTATTGAGAAATTGGTAATAATCATTTTTTT
ATGAAAATACATTTAATATAAATATTTTATAAAAGGGAAATGGATAAGGCAAAGAAAAAT
AATATAAATCAAAGTTTAAACAATCATAAATACAGTGCACCTGTGAGTAGACAAGCAAAT
CATAGTTCTGCACAAAAAACATCACCATCTAACACAAGCTATTACTAAAAGTAATCAAAT
TTAAATTTTTTAAAGATATAAATAATCTAATATAAATTCAATAGTACTTCTTTTAATAAA
ATTGGAGCCTCCACTTTAGGATAAAGAAATAGTTCTTTACTTAAATCAGTAAATATAAAA
AGAAACTGA

>TTHERM_00837850(protein)
MNIRSQRLQPMQYEFYDSNQRQESALKQNSFSKFNENNDEDELDSLIQFCSSLNKNSNNV
AKLPPKLIPVNQNIVRYLQFKPWNGVLQDNVQDSGYYFKLNNCNIKLVRGLLEENGFRET
IDKDWTIMWVVGSIKSEIYQTMMAYQKVNHFPKSIEITRKDLMNRNISKMQIRCGLSNFN
FVPKTYILPSEQSLLIEDFEKIKSTKQLFIVKPQNGSQGKNIFVTDKLNDILRANVGSGL
VVSHYVANPLLINNLKFDLRIYVAITSIHPLRVYIYEDGLVRFATQEYHADIDLLKDKYV
HLTNYSINKNSNNFVSNKDAQEDFKGSKWSLASLKDYLRVNGINVEQLFDKIEDMIVKTI
ISIEGQIFSSFEMQVPYRNNCFEVLGFDVLIDDTLKPYLLEVNLNSSLNTDSPLDLRIKG
EMLSDLFTLVGIVPLDQRYSIDQSFNFTLNSAINEKQYANIVNSLTSNWEQHKKQLTKLE
RAVLKETEDELKRCRKFKRIYPGETCFKYKNYFEQDRPFNILLRNWEMDKAKKNNINQSL
NNHKYSAPVSRQANHSSAQKTSPSNTSYYQNTSFNKIGASTLGQRNSSLLKSVNIKRN