Identifiers and Description

Gene Model Identifier

TTHERM_00997660

Standard Name

NRK4 (NIMA-Related Kinase )

Aliases

PreTt24991 | 188.m00067

Description

NRK4 plant dual-specificity MAP kinase kinase family domain protein; NIMA-Related Kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_20932.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (552 aa)
Oxytricha	Contig16193.0.g77	6.997863935131626e-107
	Description: Protein kinase domain
DictyBase	DDB_G0270814	8.001993295941272e-61
	Description: nek2 on chromosome: 1 position 4847143 to 4848761
Stentor Coeruleus	SteCoe_34801	8.408597124803643e-50
	Description: None
SGD	YAR018C	1.000499495426459e-47
	Description: KIN3 Nonessential serine/threonine protein kinase; possible role in DNA damage response
WormBase	WBGene00008956	2.9986404383886433e-43
	Description: locus:nekl-3 status:Confirmed UniProt:G5EFM9 protein_id:CAA92169.2

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00997660(coding)
ATGTCTTTGAATGATTTTGATGTAATTAGGAAATTAGGTGAAGGTGCCTATTCCAGTGTT
TTTAAAGTTCGTAAAATCAGCAATGGTTAAGATTATGCTATGAAAAATATTAAGATGGGA
AGTCTTTCTGCCAAAGAGCAAGAAAACGCTATCAACGAAGTTAGGTTCCTTGCCTCTTTG
AGCTCATAAGAGATCATTGGATATAAAGAAGCATTTTATGATGAAAAGACTGGACTCTTA
CATATAATAATGGAATATTGTGCGGGCGGTGACCTCTTAAACAAGATTCGCAATTTAAAG
AAAAAGAACCAGTATCTTGATGAGAAGGTAGTTTGGCTGTATATAATTTAGATGATTAAA
GGTTTAAAGTGTTTACATGATTTAAATATCTTGCATAGGGATTTTAAGTGTGCCAACATT
ATGCTCACTCGTGATCATAAAAATTTGAAGCTTGGAGATTTAAATGTCTCAAAAGTCGCT
AAGAAAGGGATGCTTTACACTTAGACTGGAACTCCTTATTATGCTTCTCCTGAAGTGTGG
AGAGATAAGCCTTATAATTCAAAATCAGATGTCTGGTCTCTTGGGTGTGTAATCTACGAA
TTGGTTTCTTTAAACCCACCATTCAAGGCTCAAGATATGGAAGGCTTGTTTAAGAAAGTA
CAAAAAGGGTAATATGATCCTATCCCATCTTGGTATTCATAAGATTTAACTGACTTTCTG
AGTTTGTGCTTGTAAGTAAATCCAAAAATGAGATTAACAACTTCAGAATTACTTGAAACA
CCTTACATTTAAAGAAGACTCAACATAGCCTAAGAATTGAATGTTGACTACAATCCTTTT
AATTGTGATGTAAAGTAGGAATTGCTAAAGACTCTGAAGGTAGGGAGGAATCTTAAATAA
CTTAATAACATATTGCCAGAGCCCTAATATGAGTCAACAGCTTCTTCAGAAATGAATTCT
TTTAGCAATGAAGCTAACTCAAAAAATCCAATTTCAACACAAATCAGTGATAGTTAAATT
AACAATTAACTTAATAGCCCACTTAGGCGCAACGAATAACGAAAGCTCAGCTAACCACCA
TCTTAAAAAAATATCTCTCCTGTAATCCCAAAAAAGAGTAGCCATTACAACGGAGTATAT
TCTTAGCATATGATTCCTTCTTCTAGCAATATACCCTCAATCAATTAAATTCAATCAGAA
ATGAATTTAGATGCTTATGAGCAGCGCCACAATCCCCACATCAGCAAAGCTAGCAGAAGT
AGAAGTATTGAAAATTTAATATAAATGAAGCATCCTATGAGTTCTAAAGGTTCTTAATAA
AATCTTTAATTAGGAAATCATCGTTATTAGCAAAGCAAAGATACAATTCCAACTCTCCCA
CCAATAAATGAAAATAAGAGAAATTTAATTAAATCTGTTTAAGATAATATATTAACAAAT
ATCAAACCAGTTAATTATAATAAAAACTATGATCAAGGAAGTAACAATTCATATATATCA
AAAAATTATAGTAACAAGTTAATTAATCCTATCAGTAGCCAAAATAATATAGTAAATGGT
ATTACAACAAGCGCTAACAGCATCTCGAACACAAATCTCTAGAGAGATAATAGTGTACTT
CTTTTTGCTGGTAAAAAGCTCATTTGA

>TTHERM_00997660(gene)
ATGTCTTTGAATGATTTTGATGTAATTAGGAAATTAGGTGAAGGTGCCTATTCCAGTGTT
TTTAAAGTTCGTAAAATCAGCAATGGTTAAGATTATGCTATGAAAAATATTAAGATGGGA
AGTCTTTCTGCCAAAGAGCAAGAAAACGCTATCAACGAAGTTAGGTTCCTTGCCTCTTTG
AGCTCATAAGAGATCATTGGATATAAAGAAGCATTTTATGATGAAAAGACTGGACTCTTA
CATATAATAATGGAATATTGTGCGGGCGGTGACCTCTTAAACAAGATTCGCAATTTAAAG
AAAAAGAACCAGTATCTTGATGAGAAGGTAGTTTGGCTGTATATAATTTAGATGATTAAA
GGTTTAAAGTGTTTACATGATTTAAATATCTTGCATAGGGATTTTAAGTGTGCCAACATT
ATGCTCACTCGTGATCATAAAAATTTGAAGCTTGGAGATTTAAATGTCTCAAAAGTCGCT
AAGAAAGGGATGCTTTACACTTAGACTGGAACTCCTTATTATGCTTCTCCTGAAGTGTGG
AGAGATAAGCCTTATAATTCAAAATCAGATGTCTGGTCTCTTGGGTGTGTAATCTACGAA
TTGGTTTCTTTAAACCCACCATTCAAGGCTCAAGATATGGAAGGCTTGTTTAAGAAAGTA
CAAAAAGGGTAATATGATCCTATCCCATCTTGGTATTCATAAGATTTAACTGACTTTCTG
AGTTTGTGCTTGTAAGTAAATCCAAAAATGAGATTAACAACTTCAGAATTACTTGAAACA
CCTTACATTTAAAGAAGACTCAACATAGCCTAAGAATTGAATGTTGACTACAATCCTTTT
AATTGTGATGTAAAGTAGGAATTGCTAAAGACTCTGAAGGTAGGGAGGAATCTTAAATAA
CTTAATAACATATTGCCAGAGCCCTAATATGAGTCAACAGCTTCTTCAGAAATGAATTCT
TTTAGCAATGAAGCTAACTCAAAAAATCCAATTTCAACACAAATCAGTGATAGTTAAATT
AACAATTAACTTAATAGCCCACTTAGGCGCAACGAATAACGAAAGCTCAGCTAACCACCA
TCTTAAAAAAATATCTCTCCTGTAATCCCAAAAAAGAGTAGCCATTACAACGGAGTATAT
TCTTAGCATATGATTCCTTCTTCTAGCAATATACCCTCAATCAATTAAATTCAATCAGAA
ATGAATTTAGATGCTTATGAGCAGCGCCACAATCCCCACATCAGCAAAGCTAGCAGAAGT
AGAAGTATTGAAAATTTAATATAAATGAAGCATCCTATGAGTTCTAAAGGTTCTTAATAA
AATCTTTAATTAGGAAATCATCGTTATTAGCAAAGCAAAGATACAATTCCAACTCTCCCA
CCAATAAATGAAAATAAGAGAAATTTAATTAAATCTGTTTAAGATAATATATTAACAAAT
ATCAAACCAGTTAATTATAATAAAAACTATGATCAAGGAAGTAACAATTCATATATATCA
AAAAATTATAGTAACAAGTTAATTAATCCTATCAGTAGCCAAAATAATATAGTAAATGGT
ATTACAACAAGCGCTAACAGCATCTCGAACACAAATCTCTAGAGAGATAATAGTGTACTT
CTTTTTGCTGGTAAAAAGCTCATTTGA

>TTHERM_00997660(protein)
MSLNDFDVIRKLGEGAYSSVFKVRKISNGQDYAMKNIKMGSLSAKEQENAINEVRFLASL
SSQEIIGYKEAFYDEKTGLLHIIMEYCAGGDLLNKIRNLKKKNQYLDEKVVWLYIIQMIK
GLKCLHDLNILHRDFKCANIMLTRDHKNLKLGDLNVSKVAKKGMLYTQTGTPYYASPEVW
RDKPYNSKSDVWSLGCVIYELVSLNPPFKAQDMEGLFKKVQKGQYDPIPSWYSQDLTDFL
SLCLQVNPKMRLTTSELLETPYIQRRLNIAQELNVDYNPFNCDVKQELLKTLKVGRNLKQ
LNNILPEPQYESTASSEMNSFSNEANSKNPISTQISDSQINNQLNSPLRRNEQRKLSQPP
SQKNISPVIPKKSSHYNGVYSQHMIPSSSNIPSINQIQSEMNLDAYEQRHNPHISKASRS
RSIENLIQMKHPMSSKGSQQNLQLGNHRYQQSKDTIPTLPPINENKRNLIKSVQDNILTN
IKPVNYNKNYDQGSNNSYISKNYSNKLINPISSQNNIVNGITTSANSISNTNLQRDNSVL
LFAGKKLI